Use of microvesicles in analyzing nucleic acid profiles

ABSTRACT

The invention concerns gene signatures obtained from microvesicles and a method of applying these gene signatures in helping to determine a biological condition. The determination of a biological condition may aid, for example, the diagnosis, prognosis, and therapy treatment selection for a disease in a subject.

CROSS REFERENCE TO RELATED APPLICATIONS

This application claims the benefit of priority under 35 U.S.C. §119(e)of U.S. Provisional Application Ser. No. 61/241,014 filed Sep. 9, 2009,the contents of which are incorporated herein by reference in theirentirety.

FIELD OF INVENTION

The present invention relates to the general fields of nucleic acidanalysis in human or other animal subjects, particularly the profilingof nucleic acids from a biological sample, and in particular, frommicrovesicles.

BACKGROUND

Cancer molecular diagnostics is becoming increasingly important with theaccumulating knowledge of the molecular mechanisms underlying varioustypes of cancers and the implications for diagnosis, treatment selectionand prognosis.

Various molecular diagnostic tests like mutational analysis, methylationstatus of genomic DNA and gene expression analysis are currently beingused to answer clinical questions. Differential gene expression analysisof cancer cells has so far primarily been done on cancer cells derivedfrom surgically removed tumor tissue or from tissue obtained by biopsy.However, the ability to profile gene expression using a blood samplefrom a cancer patient rather than a tissue sample is desirable because anon-invasive approach such as this has wide ranging implications interms of patient welfare, the ability to conduct longitudinal diseasemonitoring, and the ability to obtain expression profiles even whentissue cells are not easily accessible, e.g., in ovarian or brain cancerpatients.

So far, gene expression profiling using a blood sample is confined toanalyzing RNA extracted from Peripheral Blood Mononuclear Cells (PBMC)(Hakonarson et al., 2005) or Circulating Tumor Cells (CTC)(Cristofanilli and Mendelsohn, 2006). This invention discloses a novelmethod of profiling gene expressions and provides novel gene expressionsignatures associated with diseases by analyzing nucleic acids extractedfrom microvesicles from a bodily fluid, e.g., a blood sample.

BRIEF SUMMARY OF THE INVENTION

The present invention provides genetic profiles associated withbiological conditions and methods of applying these profiles inevaluating the biological conditions. As such, in one aspect, thepresent invention is directed to a profile of one or more RNAtranscripts obtained from microvesicles. The one or more RNA transcriptsare selected from those listed in Tables 1-20. In one embodiment, themicrovesicles from which the profile is obtained are isolated from abodily fluid from a subject. The bodily fluid may be blood, serum,plasma or urine. In a further embodiment, the subject is a humansubject. In an even further embodiment, the human subject is a braincancer patient such as a glioblastoma patient.

In another embodiment, the profile is obtained through analyzing RNAtranscripts obtained from microvesicles. The analysis of RNA transcriptsis performed by a method such as microarray analysis, ReverseTranscription PCR, Quantitative PCR or a combination of these abovemethods. In a further embodiment, the analysis includes an additionalstep of data analysis. The data analysis can be accomplished withClustering Analysis, Principle Component Analysis, Linear DiscriminantAnalysis, Receiver Operating Characteristic Curve Analysis, BinaryAnalysis, Cox Proportional Hazards Analysis, Support Vector Machines andRecursive Feature Elimination (SVM-RFE), Classification to NearestCentroid, Evidence-based Analysis, or a combination of the abovemethods. In yet another embodiment, the profile obtained frommicrovesicles is a profile of the one or more RNA transcripts selectedfrom any one of the Tables 1-20. In yet another embodiment, the profilefrom microvesicles is a profile of each of the RNA transcripts listed inany one of the Tables 1-20.

In another aspect, the present invention refers to a method of aidingdiagnosis, prognosis or therapy treatment planning for a subject,comprising the steps of: a) isolating microvesicles from a subject; b)measuring the expression level of one or more RNA transcripts extractedfrom the isolated microvesicles; c) determining a profile of the one ormore RNA transcripts based on the expression level; and d) comparing theprofile to a reference profile to aid diagnosis, prognosis or therapytreatment planning for the subject. In one embodiment, the microvesiclesused in the method are isolated from a bodily fluid from the subject.The bodily fluid may be blood, serum, plasma or urine. In a furtherembodiment, the subject is a human subject. In an even furtherembodiment, the human subject is a brain cancer patient such as aglioblastoma patient. The step (b) in the method is accomplished with amicroarray analysis, Reverse Transcription PCR, Quantitative PCR or acombination of the above methods. In a further embodiment, the step (c)in the method includes an additional step of data analysis. The dataanalysis can be accomplished with Clustering Analysis, PrincipleComponent Analysis, Linear Discriminant Analysis, Receiver OperatingCharacteristic Curve Analysis, Binary Analysis, Cox Proportional HazardsAnalysis, Support Vector Machines and Recursive Feature Elimination(SVM-RFE), Classification to Nearest Centroid, Evidence-based Analysis,or a combination of the above methods. The RNA transcripts whoseprofiles are determined in are one or more RNA transcripts selected fromthose listed in Tables 1-20. In yet another embodiment, the RNAtranscripts whose profiles are determined include one or more RNAtranscripts selected from any one of the Tables 1-20. In a furtherembodiment, the RNA transcripts are all of the transcripts listed in anyone of Tables 1-20.

In yet another aspect, the present invention refers to a method ofpreparing a personalized genetic profile report for a subject,comprising the steps of: (a) isolating microvesicles from a subject; (b)detecting or measuring one or more genetic aberrations within theisolated microvesicles; (c) determining one or more genetic profilesfrom the data obtained from steps (a) and (b); (d) optionally comparingthe one or more genetic profiles to one or more reference profiles; and(e) creating a report summarizing the data obtained from steps (a)through (d) and optionally including diagnostic, prognostic ortherapeutic treatment information. In one embodiment of the method, step(b) comprises the quantitative measurement of one or more nucleic acidswithin the isolated microvesicles and step (c) comprises thedetermination of one or more quantitative nucleic acid profiles. Inanother embodiment of the method, the one or more nucleic acids are RNAtranscripts selected from Tables 1-20. In a further embodiment of themethod, the one or more nucleic acids are RNA transcripts selected fromany one of Tables 1-20. In another further embodiment of the method, oneor more nucleic acids comprise each of the RNA transcripts in any one ofthe Tables 1-20.

In yet another aspect, the present invention is a kit for geneticanalysis of an exosome preparation from a body fluid sample from asubject, comprising, in a suitable container, one or more reagentssuitable for hybridizing to or amplifying one or more of the RNAtranscripts selected from Tables 1-20. In one embodiment, the kitincludes one or more reagents suitable for hybridizing to or amplifyingone or more of the RNA transcripts selected from any one of Tables 1-20.In another embodiment, the kit includes one or more reagents suitablefor hybridizing to or amplifying each of the RNA transcripts in any oneof Tables 1-20.

In yet another aspect, the present invention is a custom-designedoligonucleotide microarray for genetic analysis of an exosomepreparation from a body fluid sample from a subject, wherein the oligoson the array exclusively hybridize to one or more transcripts selectedfrom any one of Tables 1-20.

In yet another aspect, the present invention is a method of identifyingat least one potential biomarker for a disease or other medicalcondition, the method comprising: (a) isolating microvesicles fromsubjects having a disease or other medical condition of interest andfrom subjects who do not have the disease or other medical condition ofinterest; (b) measuring the expression level of a target RNA transcriptextracted from the isolated microvesicles from each of the subjects; (c)comparing the measured levels of the target RNA transcript from each ofthe subjects; and (d) determining whether there is a statisticallysignificant difference in the measured levels; wherein a determinationresulting from step (d) of a statistically significant difference in themeasured levels identifies the target RNA transcript and itscorresponding gene as potential biomarkers for the disease or othermedical condition. Preferably, the target RNA transcript is selectedfrom Tables 1-20.

In yet another aspect, the present invention is a method of profilinggenetic aberrations in a subject, comprising the steps of: (a) isolatingmicrovesicles from a subject; (b) detecting or measuring one or moregenetic aberrations within the isolated microvesicles; and (c)determining one or more genetic profiles from the data obtained fromsteps (a) and (b). In one embodiment of the method, step (b) comprisesthe quantitative measurement of one or more nucleic acids within theisolated microvesicles and step (c) comprises the determination of oneor more quantitative nucleic acid profiles. In a further embodiment ofthe method, the one or more nucleic acids are RNA transcripts selectedfrom Tables 1-20. In another embodiment, the one or more nucleic acidsare RNA transcripts selected from any one of Tables 1-20. In yet anotherfurther embodiment, the one or more nucleic acids comprise each of theRNA transcripts in any one of Tables 1-20. In any of the inventivemethods, a step of enriching the isolated microvesicles formicrovesicles originating from a specific cell type may be optionallyincluded.

The present invention may be as defined in any one of the followingnumbered paragraphs.

-   1. A profile of one or more RNA transcripts obtained from    microvesicles, wherein the one or more RNA transcripts are selected    from Tables 1-20.-   2. The profile of paragraph 1, wherein the microvesicles are    isolated from a bodily fluid from a subject.-   3. The profile of paragraph 2, wherein the bodily fluid is blood,    serum, plasma or urine.-   4. The profile of paragraph 2, wherein the subject is a human    subject.-   5. The profile of paragraph 4, wherein the human subject is a brain    cancer patient.-   6. The profile of paragraph 5, wherein the brain cancer is    glioblastoma.-   7. The profile of paragraph 1, wherein the profile is obtained    through analyzing RNA transcripts obtained from microvesicles.-   8. The profile of paragraph 7, wherein the analysis of RNA    transcripts is performed by a method comprising microarray analysis,    Reverse Transcription PCR, Quantitative PCR or a combination    thereof.-   9. The profile of paragraph 8, wherein the analytic method further    comprises data analysis.-   10. The profile of paragraph 9, wherein the data analysis comprises    Clustering Analysis,

Principle Component Analysis, Linear Discriminant Analysis, ReceiverOperating Characteristic Curve Analysis, Binary Analysis, CoxProportional Hazards Analysis, Support Vector Machines and RecursiveFeature Elimination (SVM-RFE), Classification to Nearest Centroid,Evidence-based Analysis, or a combination thereof.

-   11. The profile of paragraph 10, wherein the data analysis comprises    Clustering Analysis, Principle Component Analysis, Linear    Discriminant Analysis, or a combination thereof.-   12. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 1.-   13. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 1.-   14. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 2.-   15. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 2.-   16. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 3.-   17. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 3.-   18. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 4.-   19. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 4.-   20. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 5.-   21. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 5.-   22. The profile paragraph 1, wherein the one or more RNA transcripts    are selected from Table 6.-   23. The profile of paragraph 1, wherein the one or more RNAs    transcripts comprise each of the transcripts in Table 6.-   24. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 7.-   25. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 7.-   26. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 8.-   27. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 8.-   28. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 9.-   29. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 9.-   30. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 10.-   31. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 10.-   32. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 11.-   33. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 11.-   34. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 12.-   35. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 12.-   36. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 13.-   37. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 13.-   38. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 14.-   39. The profile of paragraph 1, wherein the one or more RNA    transcript comprise each of the transcripts in Table 14.-   40. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 15.-   41. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 15.-   42. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 16.-   43. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 16.-   44. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 17.-   45. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 17.-   46. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 18.-   47. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 18.-   48. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 19.-   49. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 19.-   50. The profile of paragraph 1, wherein the one or more RNA    transcripts are selected from Table 20.-   51. The profile of paragraph 1, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 20.-   52. A method of aiding diagnosis, prognosis or therapy treatment    planning for a subject, comprising:    -   a. isolating microvesicles from a subject;    -   b. measuring the expression level of one or more RNA transcripts        extracted from the isolated microvesicles;    -   c. determining a profile of the one or more RNA transcripts        based on the expression level; and    -   d. comparing the profile to a reference profile to aid        diagnosis, prognosis or therapy treatment planning for the        subject.-   53. The method of paragraph 52, wherein the microvesicles are    isolated from a bodily fluid from the subject.-   54. The method of paragraph 53, wherein the bodily fluid is blood,    plasma, serum or urine.-   55. The method of paragraph 53, wherein the subject is a human    subject.-   56. The method of paragraph 55, wherein the human subject is a brain    cancer patient.-   57. The method of paragraph 55, wherein the brain cancer is    glioblastoma.-   58. The method of paragraph 52, wherein step (b) is performed by a    method comprising microarray analysis, Reverse Transcription PCR,    Quantitative PCR or a combination thereof.-   59. The method of paragraph 52, wherein step (c) performed by a    method of data analysis.-   60. The method of paragraph 59, wherein the data analysis comprises    Clustering Analysis, Principle Component Analysis, Linear    Discriminant Analysis, Receiver Operating Characteristic Curve    Analysis, Binary Analysis, Cox Proportional Hazards Analysis,    Support Vector Machines and Recursive Feature Elimination (SVM-RFE),    Classification to Nearest Centroid, Evidence-based Analysis, or a    combination thereof.-   61. The method of paragraph 60, wherein the data analysis comprises    Clustering Analysis, Principle Component Analysis, Linear    Discriminant Analysis, or a combination thereof.-   62. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Tables 1-16.-   63. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 1.-   64. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 1.-   65. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 2.-   66. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 2.-   67. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 3.-   68. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 3.-   69. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 4.-   70. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 4.-   71. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 5.-   72. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 5.-   73. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 6.-   74. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 6.-   75. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 7.-   76. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 7.-   77. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 8.-   78. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 8.-   79. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 9.-   80. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 9.-   81. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 10.-   82. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 10.-   83. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 11.-   84. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 11.-   85. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 12.-   86. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 12.-   87. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 13.-   88. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts in Table 13.-   89. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 14.-   90. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 14.-   91. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 15.-   92. The method in paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 15.-   93. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 16.-   94. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 16.-   95. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 17.-   96. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 17.-   97. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 18.-   98. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 18.-   99. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 19.-   100. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 19.-   101. The method of paragraph 52, wherein the one or more RNA    transcripts are selected from Table 20.-   102. The method of paragraph 52, wherein the one or more RNA    transcripts comprise each of the transcripts from Table 20.-   103. A method of preparing a personalized genetic profile report for    a subject, comprising the steps of:    -   (a) isolating microvesicles from a subject;    -   (b) detecting or measuring one or more genetic aberrations        within the isolated microvesicles;    -   (c) determining one or more genetic profiles from the data        obtained from steps (a) and (b);    -   (d) optionally comparing the one or more genetic profiles to one        or more reference profiles; and    -   (e) creating a report summarizing the data obtained from        steps (a) through (d) and optionally including diagnostic,        prognostic or therapeutic treatment information.-   104. The method of paragraph 103, wherein step (b) comprises the    quantitative measurement of one or more nucleic acids within the    isolated microvesicles and step (c) comprises the determination of    one or more quantitative nucleic acid profiles.-   105. The method of paragraph 104, wherein the one or more nucleic    acids are RNA transcripts selected from Tables 1-20.-   106. The method of paragraph 104, wherein the one or more nucleic    acids are RNA transcripts selected from any one of Tables 1-20.-   107. The method of paragraph 104, wherein the one or more nucleic    acids comprise each of the RNA transcripts in any one of Tables    1-20.-   108. A kit for genetic analysis of an exosome preparation from a    body fluid sample from a subject, comprising, in a suitable    container, one or more reagents suitable for hybridizing to or    amplifying one or more of the RNA transcripts selected from Tables    1-20.-   109. The kit of paragraph 108, comprising one or more reagents    suitable for hybridizing to or amplifying one or more of the RNA    transcripts selected from any one of Tables 1-20.-   110. The kit of paragraph 108, comprising one or more reagents    suitable for hybridizing to or amplifying each of the RNA    transcripts in any one of Tables 1-20.-   111. An oligonucleotide microarray for genetic analysis of an    exosome preparation from a body fluid sample from a subject, wherein    the oligos on the array are custom-designed to hybridize exclusively    to one or more transcripts selected from Tables 1-20.-   112. A method of identifying at least one potential biomarker for a    disease or other medical condition, the method comprising:    -   (a) isolating microvesicles from subjects having a disease or        other medical condition of interest and from subjects who do not        have the disease or other medical condition of interest;    -   (b) measuring the expression level of a target RNA transcript        extracted from the isolated microvesicles from each of the        subjects;    -   (c) comparing the measured levels of the target RNA transcript        from each of the subjects; and    -   (d) determining whether there is a statistically significant        difference in the measured levels;-   113. The method of paragraph 112, wherein a determination resulting    from step (d) of a statistically significant difference in the    measured levels identifies the target RNA transcript and its    corresponding gene as potential biomarkers for the disease or other    medical condition, and wherein the target RNA transcript is selected    from Tables 1-20.-   114. A method of profiling genetic aberrations in a subject,    comprising the steps of:    -   (a) isolating microvesicles from a subject;    -   (b) detecting or measuring one or more genetic aberrations        within the isolated microvesicles;    -   (c) determining one or more genetic profiles from the data        obtained from steps (a) and (b).-   115. The method of paragraph 114, wherein step (b) comprises the    quantitative measurement of one or more nucleic acids within the    isolated microvesicles and step (c) comprises the determination of    one or more quantitative nucleic acid profiles.-   116. The method of paragraph 114, wherein the one or more nucleic    acids are RNA transcripts selected from Tables 1-20.-   117. The method of paragraph 114, wherein the one or more nucleic    acids are RNA transcripts selected from any one of Tables 1-20.-   118. The method of paragraph 114, wherein the one or more nucleic    acids comprise each of the RNA transcripts in any one of Tables    1-20.-   119. The method of any of paragraphs 52, 103, 112 or 114, further    comprising the step of enriching the isolated microvesicles for    microvesicles originating from a specific cell type.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1A. Heatmap and Clustering diagram illustrating microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 5×10⁻⁴ and with the log-median-ratio (i.e. the logarithm to theratio between the median expression level of a given gene in GBMs andthe same gene in Ctrls, log(median(GeneX(GBMs))/median(GeneX(Ctrls))))being at least “1” or above, or with a P value less than or equal to2×10⁻⁶. The genes included in the data set are listed in Table 1.

FIG. 1B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 1A with the same samples, thesame genes and the same inclusion criteria.

FIG. 2A. Heatmap and Clustering diagram illustrating microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 5×10⁻⁴ and with the log-median-ratio being at least “1” orabove. The genes included in the data set are listed in Table 2.

FIG. 2B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 2A with the same samples, thesame genes and the same inclusion criteria.

FIG. 3A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10⁻³ and with the log-median-ratio being at least “1” orabove. The genes included in the data set are listed in Table 3.

FIG. 3B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 3A with the same samples, thesame genes and the same inclusion criteria.

FIG. 4A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 2×10⁻⁶. The genes included in the data set are listed in Table4.

FIG. 4B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 4A with the same samples, thesame genes and the same inclusion criteria.

FIG. 5A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10⁻⁵. The genes included in the data set are listed in Table5.

FIG. 5B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 5A with the same samples, thesame genes and the same inclusion criteria.

FIG. 6A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10−4 and with the log-median-ratio being at least “0.8” orabove, or being at least “−0.8” or below. The genes included in the dataset are listed in Table 6.

FIG. 6B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 6A with the same samples, thesame genes and the same inclusion criteria.

FIG. 7A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10⁻⁵ and with the log-median-ratio being at least “0.585” orabove, the log-median-ratio being at least “0.8” or above, or being atleast “−0.585” or below. The genes included in the data set are listedin Table 7.

FIG. 7B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 7A with the same samples, thesame genes and the same inclusion criteria.

FIG. 8A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10 and with the log-median-ratio being at least “1” or above,or being at least “−1” or below. The genes included in the data set arelisted in Table 8.

FIG. 8B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 8A with the same samples, thesame genes and the same inclusion criteria.

FIG. 9A. Heatmap and Clustering diagram illustrating the microarray datashowing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10⁻⁵ and with the log-median-ratio being below “0”. The genesincluded in the data set are listed in Table 9.

FIG. 9B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 9A with the same samples, thesame genes and the same inclusion criteria.

FIG. 10A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10⁻⁵ and with the log-median-ratio being above “0”. The genesincluded in the data set are listed in Table 10.

FIG. 10B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 10A with the same samples, thesame genes and the same inclusion criteria.

FIG. 11A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. The heatmap shown is a part of theheatmap showing the expression of the genes listed in Table 11. For eachof the genes included in the data set, the expression levels in the GBMsamples and in the control samples are significantly different with a Pvalue less than or equal to 1×10⁻⁴.

FIG. 11B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 11A with the same samples, thesame genes and the same inclusion criteria.

FIG. 12A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 1×10⁻³ and with the log-median-ratio being at least “1” orabove, or being “−1” or below. The genes included in the data set arelisted in Table 12.

FIG. 12B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 12A with the same samples, thesame genes and the same inclusion criteria.

FIG. 13A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 0.05 and with the log-median-ratio being at least “1” or above,or being “−1” or below. The genes included in the data set are listed inTable 13.

FIG. 13B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 13A with the same samples, thesame genes and the same inclusion criteria.

FIG. 14A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 0.05 and with the log-median-ratio being at least “0.585” orabove. The genes included in the data set are listed in Table 14.

FIG. 14B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 14A with the same samples, thesame genes and the same inclusion criteria.

FIG. 15A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. For each of the genes included inthe data set, the expression levels in the GBM samples and in thecontrol samples are significantly different with a P value less than orequal to 0.05 and with the log-median-ratio being at least “1” or above.The genes included in the data set are listed in Table 15.

FIG. 15B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 15A with the same samples, thesame genes and the same inclusion criteria.

FIG. 16A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. The heatmap shown is a part of theheatmap showing the expression of the genes listed in Table 16. For eachof the genes included in the data set, the expression levels in the GBMsamples and in the control samples are significantly different with a Pvalue less than or equal to 0.001.

FIG. 16B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 16A with the same samples, thesame genes and the same inclusion criteria.

FIG. 17. Volcano plot of −log(p-value) of the t-test between the twogroups (GBM vs. Non-GBM) plotted against the differential expression ofeach gene between groups (M=log(GBM)-log(Ctrl), i.e. M=1 means 2-foldup-regulation).

FIG. 18A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. The heatmap shown is a part of theheatmap showing the expression of the genes listed in Table 17. For eachof the genes included in the data set, the expression levels in the GBMsamples and in the control samples are significantly different with ap≦5×10⁻² and the log-median-ratio being at least “1” or above or beingat least “−1” or below. The p-values were corrected using Benjamin andHochberg method.

FIG. 18B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 18A with the same samples, thesame genes and the same inclusion criteria.

FIG. 19A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. The heatmap shows the expressionof the genes listed in Table 18. For each of the genes included in thedata set, the expression levels in the GBM samples and in the controlsamples are significantly different with a p≦5×10⁻² and thelog-median-ratio being at least “1” or above or being at least “−1.5” orbelow. The p-values were corrected using Benjamin and Hochberg method.

FIG. 19B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 19A with the same samples, thesame genes and the same inclusion criteria.

FIG. 20A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. The heatmap shows the expressionof the genes listed in Table 19. For each of the genes included in thedata set, the expression levels in the GBM samples and in the controlsamples are significantly different with a p≦5×10⁻² and thelog-median-ratio being at least “1” or above. The p-values werecorrected using Benjamin and Hochberg method.

FIG. 20B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 20A with the same samples, thesame genes and the same inclusion criteria.

FIG. 21A. Heatmap and Clustering diagram illustrating the microarraydata showing gene expression profiles from exosomes isolated from serumsamples from Glioblastoma (GBM) and non-Glioblastoma human subjects(Ctrl). The GBM RNA samples from glioblastoma patients are named GBM11,GBM12, GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20. The controlRNA samples from non-Glioblastoma human subjects are named Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8. The heatmap shown is a part of theheatmap showing the expression of the genes listed in Table 20. For eachof the genes included in the data set, the expression levels in the GBMsamples and in the control samples are significantly different with ap≦5×10⁻² and the log-median-ratio being at least “−1.5” or below. Thep-values were corrected using Benjamin and Hochberg method.

FIG. 21B. A plot showing the result of a Principle Component Analysis(PCA) performed on the data set of FIG. 21A with the same samples, thesame genes and the same inclusion criteria.

DETAILED DESCRIPTION OF THE INVENTION

Microvesicles are shed by eukaryotic cells, or budded off of the plasmamembrane, to the exterior of the cell. These membrane vesicles areheterogeneous in size with diameters ranging from about 10 nm to about5000 nm. The small microvesicles (approximately 10 to 1000 nm, and moreoften approximately 30 to 200 nm in diameter) that are released byexocytosis of intracellular multivesicular bodies or by double inwardbudding of multivesicular bodies are referred to in the art as“exosomes.” The compositions, methods and uses described herein areequally applicable to microvesicles of all sizes; preferably 30 to 800nm; and more preferably 30 to 200 nm.

In some of the literature, the term “exosome” also refers to proteincomplexes containing exoribonucleases which are involved in mRNAdegradation and the processing of small nucleolar RNAs (snoRNAs), smallnuclear RNAs (snRNAs) and ribosomal RNAs (rRNA) (Liu et al., 2006; vanDijk et al., 2007). Such protein complexes do not have membranes and arenot “microvesicles” or “exosomes” as those terms are used here in.

Certain aspects of the present invention are based on the surprisingfinding that glioblastoma derived microvesicles can be isolated from theserum of glioblastoma patients (Skog et al., 2008). This is the firstdiscovery of microvesicles derived from cells in the brain, present in abodily fluid of a subject. Prior to this discovery it was not knownwhether glioblastoma cells produced microvesicles or whether suchmicrovesicles could cross the blood brain barrier into the rest of thebody. These microvesicles were found to contain mutant mRNA associatedwith tumor cells (Skog et al., 2008). The microvesicles also containedmicroRNAs (miRNAs) which were found to be abundant in glioblastomas(Skog et al., 2008). Glioblastoma-derived microvesicles were also foundto potently promote angiogenic features in primary human brainmicrovascular endothelial cells (HBMVEC) in culture. This angiogeniceffect was mediated at least in part through angiogenic proteins presentin the microvesicles (Skog et al., 2008). The nucleic acids found withinthese microvesicles, as well as other contents of the microvesicles suchas angiogenic proteins, can be used as valuable biomarkers for tumordiagnosis, characterization and prognosis by providing a geneticprofile. Contents within these microvesicles can also be used to monitortumor progression over time by analyzing if other mutations are acquiredduring tumor progression as well as if the levels of certain mutationsor gene expression increase or decrease over time or over a course oftreatment.

Certain aspects of the present invention are based on another findingthat most of the extracellular RNA in bodily fluid from a subject iscontained within microvesicles and thus protected from degradation byribonucleases (Skog et al., 2008). More than 90% of extracellular RNA intotal serum can be recovered in microvesicles (Skog et al., 2008).

One aspect of the present invention relates to methods for detecting,diagnosing, monitoring, treating or evaluating a disease or othermedical condition in a subject comprising the steps of, isolatingexosomes from a bodily fluid of a subject, and analyzing one or morenucleic acids contained within the exosomes. The nucleic acids areanalyzed qualitatively and/or quantitatively, and the results arecompared to results expected or obtained for one or more other subjectswho have or do not have the disease or other medical condition. Thepresence of a difference in microvesicular nucleic acid content of thesubject, as compared to that of one or more other individuals, canindicate the presence or absence of, the progression of (e.g., changesof tumor size and tumor malignancy), or the susceptibility to a diseaseor other medical condition in the subject.

The isolation methods and techniques described herein provide thefollowing heretofore unrealized advantages: 1) the opportunity toselectively analyze disease- or tumor-specific nucleic acids, which maybe realized by isolating disease- or tumor-specific microvesicles apartfrom other microvesicles within the fluid sample; 2) significantlyhigher yield of nucleic acid species with higher sequence integrity ascompared to the yield/integrity obtained by extracting nucleic acidsdirectly from the fluid sample; 3) scalability, e.g. to detect nucleicacids expressed at low levels, the sensitivity can be increased byisolating more microvesicles from a larger volume of serum; 4) purernucleic acids in that protein and lipids, debris from dead cells, andother potential contaminants and PCR inhibitors are excluded from themicrovesicle preparation before the nucleic acid extraction step; and 5)more choices in nucleic acid extraction methods as microvesiclepreparations are of much smaller volume than that of the starting serum,making it possible to extract nucleic acids from the microvesiclepreparations using small volume column filters.

The microvesicles are preferably isolated from a bodily fluid from asubject. As used herein, a “bodily fluid” refers to a sample of fluidisolated from anywhere in the body of the subject, preferably aperipheral location, including but not limited to, for example, blood,plasma, serum, urine, sputum, spinal fluid, pleural fluid, nippleaspirates, lymph fluid, fluid of the respiratory, intestinal, andgenitourinary tracts, tear fluid, saliva, breast milk, fluid from thelymphatic system, semen, cerebrospinal fluid, intra-organ system fluid,ascitic fluid, tumor cyst fluid, amniotic fluid and combinationsthereof.

The term “subject” is intended to include all animals shown to orexpected to have microvesicles. In particular embodiments, the subjectis a mammal, a human or nonhuman primate, a dog, a cat, a horse, a cow,other farm animals, or a rodent (e.g. mice, rats, guinea pig etc.). Theterm “subject” and “individual” are used interchangeably herein.

Methods of isolating microvesicles from a biological sample are known inthe art. For example, a method of differential centrifugation isdescribed in a paper by Raposo et al. (Raposo et al., 1996) and a paperby Skog et. al. (Skog et al., 2008). Methods of anion exchange and/orgel permeation chromatography are described in U.S. Pat. Nos. 6,899,863and 6,812,023. Methods of sucrose density gradients or organelleelectrophoresis are described in U.S. Pat. No. 7,198,923. A method ofmagnetic activated cell sorting (MACS) is described in (Taylor andGercel-Taylor, 2008). A method of nanomembrane ultrafiltration isdescribed in (Cheruvanky et al., 2007). Additionally, microvesicles canbe identified and isolated from bodily fluid of a subject by a recentlydeveloped microchip technology that uses a microfluidic platform toseparate tumor-derived microvesicles. This technology, as described in apaper by Nagrath et al. (Nagrath et al., 2007), can be adapted toidentify and separate microvesicles using similar principles of captureand separation as taught in the paper. Further, a method of isolatingmicrovesicles from urine samples is described in a paper by Miranda et.al. (Miranda et al., 2010) and in PCT/US2010/042365 by Russo et. al.,filed Jul. 16, 2010 (expected to publish in 2011). Each of the foregoingreferences is incorporated by reference herein for its teaching of thesemethods.

In one embodiment, the microvesicles isolated from a bodily fluid areenriched for those originating from a specific cell type, for example,lung, pancreas, stomach, intestine, bladder, kidney, ovary, testis,skin, colorectal, breast, prostate, brain, esophagus, liver, placenta,fetus cells. Because the microvesicles often carry surface moleculessuch as antigens from their donor cells, surface molecules may be usedto identify, isolate and/or enrich for microvesicles from a specificdonor cell type (Al-Nedawi et al., 2008; Taylor and Gercel-Taylor,2008). In this way, microvesicles originating from distinct cellpopulations can be analyzed for their nucleic acid content. For example,tumor (malignant and non-malignant) microvesicles carry tumor-associatedsurface antigens and may be detected, isolated and/or enriched via thesespecific tumor-associated surface antigens. In one example, the surfaceantigen is epithelial-cell-adhesion-molecule (EpCAM), which is specificto microvesicles from carcinomas of lung, colorectal, breast, prostate,head and neck, and hepatic origin, but not of hematological cell origin(Balzar et al., 1999; Went et al., 2004). In another example, thesurface antigen is CD24, which is a glycoprotein specific to urinemicrovesicles (Keller et al., 2007). In yet another example, the surfaceantigen is selected from a group of molecules including CD70,carcinoembryonic antigen (CEA), EGFR, EGFRvIII and other variants, Fasligand, TRAIL, tranferrin receptor, p38.5, p97 and HSP72. Additionally,tumor-specific microvesicles may be characterized by the lack of surfacemarkers, such as CD80 and CD86.

The isolation of microvesicles from specific cell types can beaccomplished, for example, by using antibodies, aptamers, aptameranalogs or molecularly imprinted polymers specific for a desired surfaceantigen. In one embodiment, the surface antigen is specific for a cancertype. In another embodiment, the surface antigen is specific for a celltype which is not necessarily cancerous. One example of a method ofmicrovesicle separation based on cell surface antigen is provided inU.S. Pat. No. 7,198,923. As described in, e.g., U.S. Pat. Nos. 5,840,867and 5,582,981, WO/2003/050290 and a publication by Johnson et al.(Johnson et al., 2008), aptamers and their analogs specifically bindsurface molecules and can be used as a separation tool for retrievingcell type-specific microvesicles. Molecularly imprinted polymers alsospecifically recognize surface molecules as described in, e.g., U.S.Pat. Nos. 6,525,154, 7,332,553 and 7,384,589 and a publication by Bossiet al. (Bossi et al., 2007) and are a tool for retrieving and isolatingcell type-specific microvesicles. Each of the foregoing reference isincorporated herein for its teaching of these methods.

It may be beneficial or otherwise desirable to extract the nucleic acidfrom the exosomes prior to the analysis. Nucleic acid molecules can beextracted from a microvesicle using any number of procedures, which arewell-known in the art, the particular extraction procedure chosen beingappropriate for the particular biological sample. In some instances,with some techniques, it may also be possible to analyze the nucleicacid without extraction from the microvesicle.

In one embodiment, the extracted nucleic acids, including DNA and/orRNA, are analyzed directly without an amplification step. Directanalysis may be performed with different methods including, but notlimited to, nanostring technology. NanoString technology enablesidentification and quantification of individual target molecules in abiological sample by attaching a color-coded fluorescent reporter toeach target molecule. This approach is similar to the concept ofmeasuring inventory by scanning barcodes. Reporters can be made withhundreds or even thousands of different codes allowing for highlymultiplexed analysis. The technology is described in a publication byGeiss et al. (Geiss et al., 2008) and is incorporated herein byreference for this teaching.

In another embodiment, it may be beneficial or otherwise desirable toamplify the nucleic acid of the microvesicle prior to analyzing it.Methods of nucleic acid amplification are commonly used and generallyknown in the art, many examples of which are described herein. Ifdesired, the amplification can be performed such that it isquantitative. Quantitative amplification will allow quantitativedetermination of relative amounts of the various nucleic acids, togenerate a profile as described below.

In one embodiment, the extracted nucleic acid is RNA. Preferably, theRNA is reverse-transcribed into complementary DNA before furtheramplification. Such reverse transcription may be performed alone or incombination with an amplification step. One example of a methodcombining reverse transcription and amplification steps is reversetranscription polymerase chain reaction (RT-PCR), which may be furthermodified to be quantitative, e.g., quantitative RT-PCR as described inU.S. Pat. No. 5,639,606, which is incorporated herein by reference forthis teaching.

Nucleic acid amplification methods include, without limitation,polymerase chain reaction (PCR) (U.S. Pat. No. 5,219,727) and itsvariants such as in situ polymerase chain reaction (U.S. Pat. No.5,538,871), quantitative polymerase chain reaction (U.S. Pat. No.5,219,727), nested polymerase chain reaction (U.S. Pat. No. 5,556,773),self-sustained sequence replication and its variants (Guatelli et al.,1990), transcriptional amplification system and its variants (Kwoh etal., 1989), Qb Replicase and its variants (Miele et al., 1983), cold-PCR(Li et al., 2008) or any other known nucleic acid amplification methods,followed by the detection of the amplified molecules using techniquesknown to those of skill in the art. Especially useful are thosedetection schemes designed for the detection of nucleic acid moleculesif such molecules are present in very low numbers. The foregoingreferences are incorporated herein for their teachings of these methods.

The analysis of nucleic acids present in the microvesicles isquantitative and/or qualitative. For quantitative analysis, the amounts(e.g., expression levels), either relative or absolute, of all orspecific nucleic acids of interest within the microvesicles are measuredwith methods known in the art (described below). For qualitativeanalysis, all or specific species of nucleic acids of interest withinthe microvesicles, whether wild-type or variants, are identified withmethods known in the art (described below).

A “profile” is used herein to refer to the result of a quantitativeanalysis, a qualitative analysis, or a combination of both. The analysismay be an analysis of the nucleic acids as well as other contentsextracted from a biological sample, e.g., a microvesicle. In oneembodiment, a profile of genes refers to one or more genetic aberrationsof the genes. Similarly, a profile of genes also refers to a signatureof genes herein.

A “genetic aberration” is used herein to refer to a nucleic acid amountas well as a nucleic acid variant within a biological sample, e.g., amicrovesicle. Specifically, genetic aberrations include, withoutlimitation, over-expression of a gene (e.g., oncogenes) or a panel ofgenes, under-expression of a gene (e.g., tumor suppressor genes such asp53 or RB) or a panel of genes, alternative production of splicevariants of a gene or a panel of genes, gene copy number variants (CNV)(e.g. DNA double minutes) (Hahn, 1993), nucleic acid modifications(e.g., methylation, acetylation and phosphorylations), single nucleotidepolymorphisms (SNPs), chromosomal rearrangements (e.g., inversions,deletions and duplications), and mutations (insertions, deletions,duplications, missense, nonsense, synonymous or any other nucleotidechanges) of a gene or a panel of genes, which mutations, in many cases,ultimately affect the activity and function of the gene products, leadto alternative transcriptional splicing variants and/or changes of geneexpression level.

The determination of such genetic aberrations can be performed by avariety of techniques known to the skilled practitioner. For example,expression levels of nucleic acids, alternative splicing variants,chromosome rearrangement and gene copy numbers can be determined bymicroarray analysis (U.S. Pat. Nos. 6,913,879, 7,364,848, 7,378,245,6,893,837 and 6,004,755) and quantitative PCR. Particularly, copy numberchanges may be detected with the Illumina Infinium II whole genomegenotyping assay or Agilent Human Genome CGH Microarray (Steemers etal., 2006). Nucleic acid modifications can be assayed by methodsdescribed in, e.g., U.S. Pat. No. 7,186,512 and patent publication WO2003/023065. Particularly, methylation profiles may be determined byIllumina DNA Methylation OMA003 Cancer Panel. SNPs and mutations can bedetected by hybridization with allele-specific probes, enzymaticmutation detection, chemical cleavage of mismatched heteroduplex (Cottonet al., 1988), ribonuclease cleavage of mismatched bases (Myers et al.,1985), mass spectrometry (U.S. Pat. Nos. 6,994,960, 7,074,563, and7,198,893), nucleic acid sequencing, single strand conformationpolymorphism (SSCP) (Orita et al., 1989), denaturing gradient gelelectrophoresis (DGGE) (Fischer and Lerman, 1979a; Fischer and Lerman,1979b), temperature gradient gel electrophoresis (TGGE) (Fischer andLerman, 1979a; Fischer and Lerman, 1979b), restriction fragment lengthpolymorphisms (RFLP) (Kan and Dozy, 1978a; Kan and Dozy, 1978b),oligonucleotide ligation assay (OLA), allele-specific PCR (ASPCR) (U.S.Pat. No. 5,639,611), ligation chain reaction (LCR) and its variants(Abravaya et al., 1995; Landegren et al., 1988; Nakazawa et al., 1994),flow-cytometric heteroduplex analysis (WO/2006/113590) and combinationsor modifications of any of the foregoing. Notably, gene expressionlevels may be determined by the serial analysis of gene expression(SAGE) technique (Velculescu et al., 1995). In general, the methods foranalyzing genetic aberrations are reported in numerous publications, notlimited to those cited herein, and are available to skilledpractitioners. The appropriate method of analysis will depend upon thespecific goals of the analysis, the condition and/or history of thepatient, and the specific cancer(s), diseases or other medicalconditions to be detected, monitored or treated. The forgoing referencesare incorporated herein for their teachings of these methods.

In one embodiment, the analysis is of a profile of the amounts (levels)of all or specific nucleic acids present in the microvesicle, hereinreferred to as a “quantitative nucleic acid profile” of themicrovesicles. In another embodiment, the analysis is of a profile ofthe species of all or specific nucleic acids present in themicrovesicles (both wild type as well as variants), herein referred toas a “nucleic acid species profile.” A term used herein to refer to acombination of these types of profiles is “genetic profile” which refersto the determination of the presence or absence of nucleotide species,variants and also increases or decreases in nucleic acid levels.

Once generated, these genetic profiles of the microvesicles are comparedto those expected in, or otherwise derived from a healthy normalindividual. A profile can be a genome-wide profile (representing allpossible expressed genes or DNA sequences). It can be narrower as well,such as a cancer-wide profile (representing all possible genes ornucleic acids derived from or associated with cancer). Where a specificcancer is suspected or known to exist, the profile can be specific tothat cancer (e.g., representing all possible genes or nucleic acidsderived from or associated with the cancer or various clinicallydistinct subtypes of that cancer or known drug-resistant or sensitiveforms of the cancer).

The methods of nucleic acid isolation, amplification and analysis areroutine for one skilled in the art and examples of protocols can befound, for example, in Molecular Cloning: A Laboratory Manual (3-VolumeSet) Ed. Joseph Sambrook, David W. Russel, and Joe Sambrook, Cold SpringHarbor Laboratory, 3rd edition (Jan. 15, 2001), ISBN: 0879695773. Aparticular useful protocol source for methods used in PCR amplificationis PCR Basics: From Background to Bench by Springer Verlag; 1st edition(Oct. 15, 2000), ISBN: 0387916008.

Many methods of diagnosis performed on a tumor biopsy sample can beperformed with microvesicles since tumor cells are known to shedmicrovesicles into bodily fluid and the genetic aberrations within thesemicrovesicles are reflective of those within the tumor cells themselves(Skog et al., 2008). Furthermore, methods of diagnosis usingmicrovesicles have characteristics that are absent in methods ofdiagnosis performed directly on a tumor biopsy sample. For example, oneparticular advantage of the analysis of microvesicular nucleic acids, asopposed to other forms of sampling of tumor/cancer nucleic acid, is theavailability for analysis of tumor/cancer nucleic acids derived from allfoci of a tumor or genetically heterogeneous tumors present in anindividual. Biopsy samples are limited in that they provide informationonly about the specific focus of the tumor from which the biopsy isobtained. Different tumorous/cancerous foci found within the body, oreven within a single tumor often have different genetic profiles, all ofwhich are not analyzed in a standard biopsy. However, analysis of themicrovesicular nucleic acids from an individual has the potential toprovide a sampling of all foci within an individual. This providesvaluable information with respect to recommended treatments, treatmenteffectiveness, disease prognosis, and analysis of disease recurrence,which cannot be provided by a simple biopsy.

Aspects of the present invention relate to a method for monitoringdisease (e.g. cancer) progression in a subject, and also to a method formonitoring disease recurrence in an individual. These methods comprisethe steps of isolating microvesicles from a bodily fluid of anindividual, as discussed herein, and analyzing nucleic acid within themicrovesicles as discussed herein (e.g. to create a genetic profile ofthe microvesicles). The presence or absence of a certain geneticaberration or profile is used to indicate the presence or absence of thedisease (e.g., cancer) in the subject as discussed herein. The processis performed periodically over time, and the results reviewed, tomonitor the progression or regression of the disease, or to determinerecurrence of the disease. Put another way, a change in themicrovesicular genetic profile indicates a change in the disease statein the subject. The period of time to elapse between sampling ofmicrovesicles from the subject, for performance of the isolation andanalysis of the microvesicles, will depend upon the circumstances of thesubject, and is to be determined by the skilled practitioner. Such amethod would be extremely beneficial when analyzing nucleic acid from agene that is associated with the therapy undergone by the subject. Forexample, a gene which is targeted by the therapy can be monitored forthe development of mutations which make it resistant to the therapy,upon which time the therapy can be modified accordingly. The monitoredgene may also be one which indicates specific responsiveness to aspecific therapy.

Aspects of the present invention also relate to the fact that a varietyof non-cancer diseases and/or medical conditions also have genetic linksand/or causes, and such diseases and/or medical conditions can likewisebe diagnosed and/or monitored by the methods described herein. Many suchdiseases are metabolic, infectious or degenerative in nature. One suchdisease is diabetes (e.g. diabetes insipidus) in which the vasopressintype 2 receptor (V2R) is modified. Another such disease is kidneyfibrosis in which genetic profiles for the genes of collagens,fibronectin and TGF-β are changed. Changes in genetic profiles due tosubstance abuse, viral and/or bacterial infection, and hereditarydisease states can likewise be detected by the methods described herein.

Diseases or other medical conditions for which the inventions describedherein are applicable include, but are not limited to, nephropathy,diabetes insipidus, diabetes mellitus, diabetes type I, diabetes II,renal disease glomerulonephritis, bacterial or viralglomerulonephritides, IgA nephropathy, Henoch-Schonlein Purpura,membranoproliferative glomerulonephritis, membranous nephropathy,Sjogren's syndrome, nephrotic syndrome minimal change disease, focalglomerulosclerosis and related disorders, acute renal failure, acutetubulointerstitial nephritis, pyelonephritis, GU tract inflammatorydisease, Pre-clampsia, renal graft rejection, leprosy, refluxnephropathy, nephrolithiasis, genetic renal disease, medullary cystic,medullar sponge, polycystic kidney disease, autosomal dominantpolycystic kidney disease, autosomal recessive polycystic kidneydisease, tuberous sclerosis, von Hippel-Lindau disease, familialthin-glomerular basement membrane disease, collagen III glomerulopathy,fibronectin glomerulopathy, Alport's syndrome, Fabry's disease,Nail-Patella Syndrome, congenital urologic anomalies, monoclonalgammopathies, multiple myeloma, amyloidosis and related disorders,febrile illness, familial Mediterranean fever, HIV infection-AIDS,inflammatory disease, systemic vasculitides, polyarteritis nodosa,Wegener's granulomatosis, polyarteritis, necrotizing and crecenticglomerulonephritis, polymyositis-dermatomyositis, pancreatitis,rheumatoid arthritis, systemic lupus erythematosus, gout, blooddisorders, sickle cell disease, thrombotic thrombocytopenia purpura,Fanconi's syndrome, transplantation, acute kidney injury, irritablebowel syndrome, hemolytic-uremic syndrome, acute corticol necrosis,renal thromboembolism, trauma and surgery, extensive injury, burns,abdominal and vascular surgery, induction of anesthesia, side effect ofuse of drugs or drug abuse, circulatory disease myocardial infarction,cardiac failure, peripheral vascular disease, hypertension, coronaryheart disease, non-atherosclerotic cardiovascular disease,atherosclerotic cardiovascular disease, skin disease, psoriasis,systemic sclerosis, respiratory disease, COPD, obstructive sleep apnoea,hypoia at high altitude or endocrine disease, or acromegaly.

Selection of an individual from whom the microvesicles are isolated isperformed by the skilled practitioner based upon analysis of one or moreof a variety of factors. Such factors for consideration are whether thesubject has a family history of a specific disease (e.g., a cancer), hasa genetic predisposition for such a disease, has an increased risk forsuch a disease, or has physical symptoms which indicate apredisposition, or environmental reasons. Environmental reasons includelifestyle, exposure to agents which cause or contribute to the diseasesuch as in the air, land, water or diet. In addition, having previouslyhad the disease, being currently diagnosed with the disease prior totherapy or after therapy, being currently treated for the disease(undergoing therapy), being in remission or recovery from the disease,are other reasons to select an individual for performing the methods.

The cancer diagnosed, monitored or otherwise profiled, can be any kindof cancer. This includes, without limitation, epithelial cell cancerssuch as lung, ovarian, cervical, endometrial, breast, brain, colon andprostate cancers. Also included are gastrointestinal cancer, head andneck cancer, non-small cell lung cancer, cancer of the nervous system,kidney cancer, retina cancer, skin cancer, liver cancer, pancreaticcancer, genital-urinary cancer and bladder cancer, melanoma, andleukemia. In addition, the methods and compositions of the presentinvention are equally applicable to detection, diagnosis and prognosisof non-malignant tumors in an individual (e.g., neurofibromas,meningiomas and schwannomas).

In one embodiment, the cancer is brain cancer. Types of brain tumors andcancer are well known in the art. Glioma is a general name for tumorsthat arise from the glial (supportive) tissue of the brain. Gliomas arethe most common primary brain tumors. Astrocytomas, ependymomas,oligodendrogliomas, and tumors with mixtures of two or more cell types,called mixed gliomas, are the most common gliomas. The following areother common types of brain tumors: Acoustic Neuroma (Neurilemmoma,Schwannoma. Neurinoma), Adenoma, Astracytoma, Low-Grade Astrocytoma,giant cell astrocytomas, Mid- and High-Grade Astrocytoma, Recurrenttumors, Brain Stem Glioma, Chordoma, Choroid Plexus Papilloma, CNSLymphoma (Primary Malignant Lymphoma), Cysts, Dermoid cysts, Epidermoidcysts, Craniopharyngioma, Ependymoma Anaplastic ependymoma,Gangliocytoma (Ganglioneuroma), Ganglioglioma, Glioblastoma Multiforme(GBM), Malignant Astracytoma, Glioma, Hemangioblastoma, Inoperable BrainTumors, Lymphoma, Medulloblastoma (MDL), Meningioma, Metastatic BrainTumors, Mixed Glioma, Neurofibromatosis, Oligodendroglioma. Optic NerveGlioma, Pineal Region Tumors, Pituitary Adenoma, PNET (PrimitiveNeuroectodermal Tumor), Spinal Tumors, Subependymoma, and TuberousSclerosis (Bourneville's Disease).

As an exemplary embodiment of the present invention, one aspect of thepresent invention is a method of analyzing RNA profiles usingmicrovesicles isolated from brain cancer serum samples. The methodcomprises the steps of isolating microvesicles from brain cancer serumsamples and analyzing nucleic acids extracted from the isolatedmicrovesicles.

As an exemplary embodiment of the present invention, another aspect ofthe present intention is the discovery of a series of brain cancer geneexpression profiles or signatures. The signatures were discovered byanalyzing nucleic acids extracted from brain cancer serum samples. Thesignatures can be used for the diagnosis and/or prognosis of braincaner, as well as treatment plan evaluation, selection and monitoring ofbrain cancer.

The exemplary embodiment of the present invention is illustrated in thefollowing example for both method and signature aspects. In thisexample, gene signatures for glioblastoma cancer were obtained usingmethods and materials detailed below.

Blood samples from patients diagnosed with de-novo primary GBM werecollected immediately prior to surgery, before opening of the duramater, into a BD Vacutainer SST (#367985) at Massachusetts GeneralHospital (MGH). Blood from normal healthy controls was collected fromvolunteers recruited at the MGH blood bank. All samples were collectedwith informed consent according to the appropriate protocols approved bythe Institutional Review Board at MGH. The blood was left to clot for 30min and serum was isolated according to manufacturer's recommendationswithin two hours of collection. Serum was filtered by slowly passing itthrough a 0.8 μm syringe filter, aliquoted into 1.8 milliliter (ml)cryotubes and kept at −80° C. until used. Altogether, 9 serum samplesfrom glioblastoma patients and 7 serum samples from non-glioblastomahuman subjects were obtained for the following analysis.

Isolation of microvesicles from serum samples was performed aspreviously described (Skog et al., 2008). Briefly, 1 ml serum wascentrifuged for 10 min at 300×g to eliminate any cell contamination.Supernatants were further centrifuged for 20 min at 16,500×g andfiltered through a 0.22 μm filter. Microvesicles were then pelleted byultracentrifugation at 110,000×g for 70 min. The microvesicle pelletswere washed in 13 ml PBS, pelleted again and resuspended in cold PBS.Isolated microvesicles were measured for their total protein contentusing DC Protein Assay (Bio-Rad, Hercules, Calif., USA).

For the extraction of RNA from microvesicles, the pelleted microvesicleswere incubated in an RNAse inhibitor solution for 5-10 minutes at roomtemperature. The RNase inhibitor can be from various known vendors,e.g., one inhibitor is “SUPERase” from Ambion Inc. Total RNA wasextracted from the RNAse-treated microvesicles using various commercialRNA extraction kits such as the QIAamp RNA Blood Mini Kit or themiRNeasy mini kit from Qiagen, or the MirYana RNA isolation kit fromAmbion Inc., according to the manufacturer's protocols. After treatmentwith DNAse according to the manufacturers' protocol, total RNA waseluted in 30 ul nuclease-free water. RNA quality and concentration wasassessed with the Agilent Bioanalyzer RNA Pico Chip yielding typicalconcentrations of 0.4-0.8 ng/μL for normal controls and 0.8-2.0 ng/μLfor GBM patients.

The extracted RNA was then analyzed using the Agilent 44K Whole HumanGenome Oligo Microarrays (one-color), a standard gene expressionanalysis tool, according to standard protocols. Briefly, for the linearT7-based amplification step, from 0.07 μg up to 0.46 μg of total RNA wasused, depending on the available amount of total RNA. To produceCy3-labeled cRNA, the RNA samples were amplified and labeled using theAgilent Low RNA Input Linear Amp Kit (Agilent Technologies) followingthe manufacturer's protocol. Yields of cRNA and the dye incorporationrate were measured with the ND-1000 Spectrophotometer (NanoDropTechnologies). The hybridization procedure was performed according tothe Agilent 60-mer oligo microarray processing protocol using theAgilent Gene Expression Hybridization Kit (Agilent Technologies).Briefly, 1.5-1.65 μg of Cy3-labeled fragmented cRNA in hybridizationbuffer was hybridized overnight (17 hours, 65° C.) to Agilent WholeHuman Genome Oligo Microarrays 4×44K using Agilent's recommendedhybridization chamber and oven. Finally, the microarrays were washedonce with the Agilent Gene Expression Wash Buffer 1 for 1 min at roomtemperature followed by a second wash with preheated Agilent GeneExpression Wash Buffer 2 (37° C.) for 1 min. The last washing step wasperformed with acetonitrile. Fluorescence signals of the hybridizedAgilent Microarrays were detected using Agilent's Microarray ScannerSystem (Agilent Technologies).

The Agilent Feature Extraction Software (FES) was used to read out andprocess the microarray image files. The software determines featureintensities (including background subtraction), rejects outliers andcalculates statistical confidences. For the determination ofdifferential gene expression, FES-derived output data files were furtheranalyzed using the Rosetta Resolver gene expression data analysis system(Rosetta Biosoftware). This software offers—among other features—theability to compare two single intensity profiles in a ratio experiment.All samples were labeled with Cy3. Here, the ratio experiments aredesignated as control versus (vs.) sample experiments (automated dataoutput of the Resolver system).

The raw data from Feature Extraction was pre-processed and normalized inseveral different ways using R/Bioconductor and the packages limma,Agi4×44PreProcess and vsn. To ensure that the normalization proceduredid not introduce unintended biases or artifacts, the data wasnormalized in three different ways using Quartile normalization with andwithout background subtraction and variance stabilized normalization(VSN), and the normalized data was compared to the raw values.Normalized data was transferred to Excel and filtered with differentcriteria as described below. Gene lists of interest were uploaded andanalyzed with the online Gene Ontology Tool DAVID 6.7(http://david.abcc.ncifcrf.gov/).

As a result, microvesicles (less than 0.8 μm in diameter) were isolatedfrom serum samples from 9 GBM patients (prior to surgery) and 7 normalhealthy controls. RNA from this exosomal fraction (exoRNA) wasextracted, labeled and amplified by linear amplification and hybridizedto Agilent 4×44K arrays. The raw data was corrected for background,normalized and submitted for deposit in the Gene Expression Omnibusdatabase by user name/ID Mikkell Noerholm on Sep. 4, 2010 in the formatof GEOarchive. The deposited file name isAgilentQuartileNorm_MeanSignal_GBMvsCTRL_GEO.zip. The deposited data arehere incorporated by reference in its entirety including the array oligosequences.

Clustering analysis, heat maps, and Principle Component Analysis of thenormalized data was performed by using various softwares, e.g.GeneSifter, provided various sources, e.g., dChip(http://biosun1.harvard.edu/complab/dchip). A clustering analysis forgenome-wide expression data from DNA microarray hybridization usesstandard statistical algorithms to cluster genes according to similarityin pattern of gene expression (Eisen et al., 1998). A type of PrincipleComponent Analysis is described previously (Alter et al., 2000).

Other data analysis tools, known in the art, may be substituted for thetools described and exemplified herein. In addition to ClusteringAnalysis, Principle Component Analysis, other analytic tools such asLinear Discriminant Analysis, Receiver Operating Characteristic CurveAnalysis (Zweig and Campbell, 1993), Binary Analysis (U.S. Pat. No.7,081,340), Cox Proportional Hazards Analysis (U.S. Pat. No. 7,081,340),Support Vector Machines and Recursive Feature Elimination (SVM-RFE)(U.S. Pat. No. 7,117,188), Classification to Nearest Centroid (Dabney,2005) or combinations thereof may be used to analyze the expression dataincluding microarray data.

We conducted a t-test between the two groups of samples on each gene inthe full data set to identify the genes that best separate, distinguish,or discriminate between the two groups. As shown in FIG. 17, a volcanoplot of the p-values against the level of differential expression, it isevident that substantially more genes are significantly down-regulatedthan up-regulated in the GBM samples. The level of differentialexpression is the difference of the median expression levels in the GBMand Control groups (i.e., median level in GBM−median level in Control).The typical degree of disregulation and the significance (p-value) isalso higher for the down-regulated genes than for the up-regulatedgenes.

Based on the p values and the level of differential expression, wederived 16 different groups of genes from the above microarray data. The16 groups of genes are listed in Tables 1-16, respectively. The criteriafor inclusion of the each gene in the groups in Tables 1-16 are asfollows:

-   -   Table 1: p≦5×10⁻⁴ and with the log-median-ratio being at least        “1” or above, or p≦0.000002;    -   Table 2: p≦5×10⁻⁴ and the log-median-ratio being at least “1” or        above;    -   Table 3: p≦2×10⁻³ and the log-median-ratio being at least “1” or        above;    -   Table 4: p≦2×10⁻⁶;    -   Table 5: p≦1×10⁻⁵;    -   Table 6: p≦5×10⁻⁴ and the log-median-ratio being at least “0.8”        or above, or being at least “−0.8” or below;    -   Table 7: p≦1×10⁻⁵ and the log-median-ratio being at least        “0.585” or above, or being at least “−0.585” or below;    -   Table 8: p≦1×10⁻⁴ and the log-median-ratio being at least “1” or        above, or being at least “−1” or below;    -   Table 9: p≦1×10⁻⁵ and the log-median-ratio being below “0”;    -   Table 10: p≦1×10⁻⁵ and log-median-ratio being above “0”;    -   Table 11: p≦1×10⁻⁴;    -   Table 12: p≦1×10⁻³ and the log-median-ratio being at least “1”        or above, or being “−1” or below;    -   Table 13: p≦0.05 and the log-median-ratio being at least “1” or        above, or being “−1” or below;    -   Table 14: p≦0.05 and the log-median-ratio being at least “0.585”        or above;    -   Table 15: p≦0.05 and the log-median-ratio being at least “1” or        above; and    -   Table 16: p≦0.001.

Each of the 16 groups can be a gene signature for glioblastoma. Wetested each group for its capability as a glioblastoma signature. Foreach group, two independent tests were performed. One test usedClustering Analysis. The other test used Principle Component Analysis.For each group, the results (as illustrated in FIGS. 1-16, As and Bs,respectively) showed that at least one of the two tests separated thecancer group and the control group.

Accordingly, one embodiment of the present invention is a profile of oneor more of genes selected from the genes in Tables 1-16. In anotherembodiment, the profiles are of one or more genes selected from a singleTable, e.g., from Table 1. In a further embodiment, the profiles are ofa group of genes comprising each of the genes in a single Table, e.g.,Table 1. One or more members in each group constitute a glioblastomagene signature because either Clustering Analysis or Principle ComponentAnalysis of the expression profiles of such one or more members in eachgroup can separate the disease and control samples.

Another embodiment of the present invention is a method of applying thesignatures for aiding the diagnosis, prognosis or therapy treatment fora subject. The method comprises first isolating microvesicles from thesubject, measuring the expression levels of one or more RNA transcriptsextracted from isolated microvesicles, determining a test profile of oneor more RNA transcripts based on the measured expression level(s), andcomparing the test profile to a reference profile to determine thecharacteristics of the test profile.

For example, as shown in Table 1, the group included 22 genes based onthe inclusion criteria of p≦5×10⁻⁴ and a log-median-ratio being at least“1” or above, or p≦0.000002. The 22 genes have functionalities includingas receptors, transcription factors, and enzymes. As shown in FIG. 1A,the 22-gene signature clusters control samples together in one subgroupand disease samples together in another subgroup when subjected to aClustering Analysis. The disease samples GBM11, GBM12, GBM13, GBM15,GBM16, GBM17, GBM18, GBM19, and GBM20 cluster together in one subgroup.The control samples from non-Glioblastoma human subjects, Ctrl1, Ctrl2,Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8, clustered in another subgroup. Theseparation of GBM and Control samples can be achieved by ClusteringAnalysis. As shown in FIG. 1B, the same 22-gene signature is validatedusing Principle Component Analysis. The Control group dots appear on theupper left side of the plot while the GBM group dots appear on themiddle-right side of the plot.

Furthermore, an evidence-based analysis tool, optionally together withone or more of the Heuristic methods described above, may also be usedfor analyzing expression data. For example, a gene ontology analysis maybe carried out and genes in the same biological signaling pathway grouptogether. A signature or profile comprised of a group of genes in arelevant signaling pathway may be derived and used for the purpose ofdiagnosing a corresponding biological condition.

As a further analytical step, we performed a multiple testing correctionanalysis in which a normalized data set was subjected to an unpairedt-test. The p-values were corrected using the Benjamin and HochbergMethod (Benjamini and Hochberg, 1995) with a cut-off of corrected p<0.05and fold change of ≧2.5. As a result of the application of this method,275 genes were found to be down-regulated. Using the above-mentionedcriteria, a Gene Ontology (GO) analysis with an enrichment score of64.26 showed that 210 recognized genes had GO terms related toTranslation elongation, Ribosome, or ribonucleoprotein. Furthermore, 24genes were found to be upregulated. Using the above-mentioned criteria,a GO analysis with an enrichment score of 1.27 showed that 23 recognizedgenes had GO terms related to transcription (i.e. transcription factoractivity, transcription, DNA binding, homeobox).

Based on the p values that have been corrected using the Benjamin andHochberg Method and the level of differential expression, we derived 4additional groups of genes from the above microarray data. The 4 groupsof genes are listed in Tables 17-20, respectively. The criteria toobtain the groups in Tables 17-20 are as follows:

-   -   Table 17: p≦5×10⁻² and with the log-median-ratio being at least        “1” or above, or being at least “−1” or below;    -   Table 18: p≦5×10⁻² and the log-median-ratio being at least “1”        or above, or being at least “−1.5” or below;    -   Table 19: p≦5×10⁻² and the log-median-ratio being at least “1”        or above;    -   Table 20: p≦5×10⁻² and the log-median-ratio being at least        “−1.5” or below, respectively.

Each of the 4 groups can be a gene signature for glioblastoma. We testedeach group for its capability as a glioblastoma signature. For eachgroup, two independent tests were performed. One test used ClusteringAnalysis. The other test used Principle Component Analysis. For eachgroup, the results (as illustrated in FIGS. 18-21 As and Bs,respectively) showed that at least one of the two tests can separate thecancer group and the control group.

For example, as shown in Table 18, the group includes 31 genes based inthe inclusion criteria of p≦5×10⁻² and the log-median-ratio being atleast “1” or above, or being at least “−1.5” or below. The 31 genes havevarious functionalities including as receptors, transcription factors,and enzymes. As shown in FIG. 19A, the 31-gene signature clusterscontrol samples together in one subgroup and disease samples together inanother subgroup when subjected to Clustering Analysis. The 9 tumorsamples are easily distinguishable from and clearly form a clusterdifferent from the 7 Normal Controls. The disease samples GBM11, GBM12,GBM13, GBM15, GBM16, GBM17, GBM18, GBM19, and GBM20 cluster together inone subgroup. The control samples from non-Glioblastoma human subjects,Ctrl1, Ctrl2, Ctrl3, Ctrl4, Ctrl5, Ctrl7 and Ctrl8, clustered in anothersubgroup. The separation of GBM and Control samples can be achieved byClustering Analysis. As shown in FIG. 19B, the same 31-genes signaturewas validated using Principle Component Analysis. The Control group dotsappear on the upper left side of the plot. The GBM group dots appear onthe middle-right side of the plot.

All patents, patent applications, and publications identified areexpressly incorporated herein by reference for the purpose of describingand disclosing, for example, the methodologies described in suchpublications that might be used in connection with the presentinvention. These publications are provided solely for their disclosureprior to the filing date of the present application. Nothing in thisregard should be construed as an admission that the inventors are notentitled to antedate such disclosure by virtue of prior invention or forany other reason. All statements as to the date or representation as tothe contents of these documents is based on the information available tothe applicants and does not constitute any admission as to thecorrectness of the dates or contents of these documents.

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While the present invention has been disclosed with reference to certainembodiments, numerous modifications, alterations, and changes to thedescribed embodiments are possible without departing from the scope ofthe present invention, as defined in the appended claims. Accordingly,it is intended that the present invention not be limited to theparticular described embodiments, but that it enjoy the full scopedefined by the language of the following claims, and equivalentsthereof.

TABLE 1 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻⁴and the log-median-ratio being at least “1” or above, or p ≦ 0.000002.GenBank Accession Gene Name Description NM_173833 SCARA5 Homo sapiensscavenger receptor class A, member 5 (putative) (SCARA5), mRNA[NM_173833] NM_182688 UBE2G2 Homo sapiens ubiquitin-conjugating enzymeE2G 2 (UBC7 homolog, yeast) (UBE2G2), transcript variant 2, mRNA[NM_182688] NM_024812 BAALC Homo sapiens brain and acute leukemia,cytoplasmic (BAALC), transcript variant 1, mRNA [NM_024812] XM_372498LOC390427 PREDICTED: Homo sapiens similar to TBP-associated factor 15isoform 1 (LOC390427), mRNA [XM_372498] THC2718728 THC2718728 UnknownENST00000248668 LRFN1 Leucine-rich repeat and fibronectin type IIIdomain-containing protein 1 (Fragment). [Source: Uniprot/SPTREMBL; Acc:Q9P244] [ENST00000248668] NM_175734 C17orf74 Homo sapiens chromosome 17open reading frame 74 (C17orf74), mRNA [NM_175734] NM_004750 CRLF1 Homosapiens cytokine receptor-like factor 1 (CRLF1), mRNA [NM_004750]AA418814 AA418814 AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNAclone IMAGE: 767978 3′, mRNA sequence [AA418814] NM_203374 ZNF784 Homosapiens zinc finger protein 784 (ZNF784), mRNA [NM_203374]ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI) (Serpin B1)(Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI). [Source:Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183 FOXD3 Homosapiens forkhead box D3 (FOXD3), mRNA [NM_012183] NM_138763 BAX Homosapiens BCL2-associated X protein (BAX), transcript variant delta, mRNA[NM_138763] NM_001404 EEF1G Homo sapiens eukaryotic translationelongation factor 1 gamma (EEF1G), mRNA [NM_001404] BC107865 LOC204010Homo sapiens similar to 40S ribosomal protein SA (P40) (34/67 kDalaminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4)(Multidrug resistance-associated protein MGr1- Ag), mRNA (cDNA cloneMGC: 104447 IMAGE: 4095371), complete cds... NM_203477 MGC70863 Homosapiens similar to RPL23AP7 protein (MGC70863), transcript variant 1,mRNA [NM_203477] NM_003202 TCF7 Homo sapiens transcription factor 7(T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] NM_019059 TOMM7 Homo sapiens translocase of outermitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA [NM_019059]NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcriptvariant 1, mRNA [NM_000661] NM_033060 KRTAP4-10 Homo sapiens keratinassociated protein 4-10 (KRTAP4-10), mRNA [NM_033060] XR_018133LOC389404 PREDICTED: Homo sapiens similar to 60S ribosomal protein L9(LOC389404), mRNA [XR_018133] ENST00000333351 ENST00000333351 PREDICTED:Homo sapiens hypothetical LOC391504 (LOC391504), mRNA [XR_018627]

TABLE 2 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻⁴and the log-median-ratio being at least “1” or above. GenBank AccessionGene Name Description NM_173833 SCARA5 Homo sapiens scavenger receptorclass A, member 5 (putative) (SCARA5), mRNA [NM_173833] NM_182688 UBE2G2Homo sapiens ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)(UBE2G2), transcript variant 2, mRNA [NM_182688] NM_024812 BAALC Homosapiens brain and acute leukemia, cytoplasmic (BAALC), transcriptvariant 1, mRNA [NM_024812] XM_372498 LOC390427 PREDICTED: Homo sapienssimilar to TBP-associated factor 15 isoform 1 (LOC390427), mRNA[XM_372498] THC2718728 THC2718728 Unknown ENST00000248668 LRFN1Leucine-rich repeat and fibronectin type III domain-containing protein 1(Fragment). [Source: Uniprot/SPTREMBL; Acc: Q9P244] [ENST00000248668]NM_175734 C17orf74 Homo sapiens chromosome 17 open reading frame 74(C17orf74), mRNA [NM_175734] NM_004750 CRLF1 Homo sapiens cytokinereceptor-like factor 1 (CRLF1), mRNA [NM_004750] AA418814 AA418814AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3′, mRNA sequence [AA418814] NM_203374 ZNF784 Homo sapiens zincfinger protein 784 (ZNF784), mRNA [NM_203374] ENST00000380739 SERPINB1Leukocyte elastase inhibitor (LEI) (Serpin B1) (Monocyte/neutrophilelastase inhibitor) (M/NEI) (EI). [Source: Uniprot/SWISSPROT; Acc:P30740] [ENST00000380739] NM_012183 FOXD3 Homo sapiens forkhead box D3(FOXD3), mRNA [NM_012183] NM_138763 BAX Homo sapiens BCL2-associated Xprotein (BAX), transcript variant delta, mRNA [NM_138763]

TABLE 3 Gene list generated at the inclusion criteria of p ≦ × 10⁻³ andthe log-median-ratio being at least “1” or above. GenBank Accession GeneName Description NM_173833 SCARA5 Homo sapiens scavenger receptor classA, member 5 (putative) (SCARA5), mRNA [NM_173833] NM_182688 UBE2G2 Homosapiens ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)(UBE2G2), transcript variant 2, mRNA [NM_182688] AK000420 AK000420 Homosapiens cDNA FLJ20413 fis, clone KAT02170. [AK000420] NM_024812 BAALCHomo sapiens brain and acute leukemia, cytoplasmic (BAALC), transcriptvariant 1, mRNA [NM_024812] XM_372498 LOC390427 PREDICTED: Homo sapienssimilar to TBP-associated factor 15 isoform 1 (LOC390427), mRNA[XM_372498] THC2718728 THC2718728 Unknown NM_198253 TERT Homo sapienstelomerase reverse transcriptase (TERT), transcript variant 1, mRNA[NM_198253] NM_002307 LGALS7 Homo sapiens lectin, galactoside-binding,soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307] ENST00000248668 LRFN1Leucine-rich repeat and fibronectin type III domain-containing protein 1(Fragment). [Source: Uniprot/SPTREMBL; Acc: Q9P244] [ENST00000248668]ENST00000325151 ENST00000325151 Small inducible cytokine A27 precursor(CCL27) (CC chemokine ILC) (IL-11 R-alpha-locus chemokine) (Skinkine)(ESkine) (Cutaneous T-cell-attracting chemokine) (CTACK). [Source:Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_006266 RALGDS Homosapiens ral guanine nucleotide dissociation stimulator (RALGDS),transcript variant 1, mRNA [NM_006266] NM_001138 AGRP Homo sapiensagouti related protein homolog (mouse) (AGRP), transcript variant 1,mRNA [NM_001138] NM_207377 UNQ9438 Homo sapiens TIMM9 (UNQ9438), mRNA[NM_207377] NM_015088 TNRC6B Homo sapiens trinucleotide repeatcontaining 6B (TNRC6B), transcript variant 1, mRNA [NM_015088] NM_175734C17orf74 Homo sapiens chromosome 17 open reading frame 74 (C17orf74),mRNA [NM_175734] NM_004750 CRLF1 Homo sapiens cytokine receptor-likefactor 1 (CRLF1), mRNA [NM_004750] NM_003508 FZD9 Homo sapiens frizzledhomolog 9 (Drosophila) (FZD9), mRNA [NM_003508] AA418814 AA418814AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3′, mRNA sequence [AA418814] NM_203374 ZNF784 Homo sapiens zincfinger protein 784 (ZNF784), mRNA [NM_203374] ENST00000380739 SERPINB1Leukocyte elastase inhibitor (LEI) (Serpin B1) (Monocyte/neutrophilelastase inhibitor) (M/NEI) (EI). [Source: Uniprot/SWISSPROT; Acc:P30740] [ENST00000380739] NM_012183 FOXD3 Homo sapiens forkhead box D3(FOXD3), mRNA [NM_012183] NM_019105 TNXB Homo sapiens tenascin XB(TNXB), transcript variant XB, mRNA [NM_019105] ENST00000360514ENST00000360514 Homo sapiens hypothetical LOC339483, mRNA (cDNA cloneMGC: 52427 IMAGE: 4872239), complete cds. [BC041632] NM_138763 BAX Homosapiens BCL2-associated X protein (BAX), transcript variant delta, mRNA[NM_138763] NM_203304 RKHD1 Homo sapiens ring finger and KH domaincontaining 1 (RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiensleucine-rich repeat-containing G protein-coupled receptor 4 (LGR4), mRNA[NM_018490] CV575560 CV575560 oe37f10.y1 Human keratoconus cornea,unamplified, (od [CV575560]

TABLE 4 Gene list generated at the inclusion criteria of p ≦ 2 × 10⁻⁶.GenBank Accession Gene Name Description NM_001404 EEF1G Homo sapienseukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] BC107865 LOC204010 Homo sapiens similar to 40S ribosomalprotein SA (P40) (34/67 kDa laminin receptor) (Colon carcinomalaminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associatedprotein MGr1- Ag), mRNA (cDNA clone MGC: 104447 IMAGE: 4095371),complete cds . . . NM_203477 MGC70863 Homo sapiens similar to RPL23AP7protein (MGC70863), transcript variant 1, mRNA [NM_203477] NM_003202TCF7 Homo sapiens transcription factor 7 (T-cell specific, HMG-box)(TCF7), transcript variant 1, mRNA [NM_003202] NM_019059 TOMM7 Homosapiens translocase of outer mitochondrial membrane 7 homolog (yeast)(TOMM7), mRNA [NM_019059] NM_000661 RPL9 Homo sapiens ribosomal proteinL9 (RPL9), transcript variant 1, mRNA [NM_000661] NM_033060 KRTAP4-10Homo sapiens keratin associated protein 4-10 (KRTAP4-10), mRNA[NM_033060] XR_018133 LOC389404 PREDICTED: Homo sapiens similar to 60Sribosomal protein L9 (LOC389404), mRNA [XR_018133] ENST00000333351ENST00000333351 PREDICTED: Homo sapiens hypothetical LOC391504(LOC391504), mRNA [XR_018627]

TABLE 5 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻⁵.GenBank Accession GeneName Description THC2718728 THC2718728 UnknownNM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863),transcript variant 1, mRNA [NM_203477] NR_000029 RPL23AP7 Homo sapiensribosomal protein L23a pseudogene 7 (RPL23AP7) on chromosome 2[NR_000029] BC030568 LOC376693 Homo sapiens hypothetical LOC376693, mRNA(cDNA clone MGC: 45392 IMAGE: 5526694), complete cds. [BC030568]BC006438 BC006438 Homo sapiens cDNA clone MGC: 13162 IMAGE: 3010103,complete cds. [BC006438] ENST00000303979 ENST00000303979 UnknownXR_016879 LOC388401 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L7 (LOC388401), mRNA [XR_016879] NM_001404 EEF1G Homo sapienseukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein(MGC70863), transcript variant 1, mRNA [NM_203477] NM_001040437 C6orf48Homo sapiens chromosome 6 open reading frame 48 (C6orf48), transcriptvariant 1, mRNA [NM_001040437] XM_001128309 LOC730663 PREDICTED: Homosapiens similar to 60S ribosomal protein L23a (LOC730663), mRNA[XM_001128309] NM_001214 C16orf3 Homo sapiens chromosome 16 open readingframe 3 (C16orf3), mRNA [NM_001214] NM_001082575 HRNBP3 Homo sapienshypothetical protein LOC146713 (HRNBP3), mRNA [NM_001082575] BC107865LOC204010 Homo sapiens similar to 40S ribosomal protein SA (P40) (34/67kDa laminin receptor) (Colon carcinoma laminin-binding protein)(NEM/1CHD4) (Multidrug resistance-associated protein MGr1- Ag), mRNA(cDNA clone MGC: 104447 IMAGE: 4095371), complete cds . . . NM_203477MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863), transcriptvariant 1, mRNA [NM_203477] NM_003202 TCF7 Homo sapiens transcriptionfactor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] A_24_P93052 A_24_P93052 Unknown NM_019059 TOMM7 Homo sapienstranslocase of outer mitochondrial membrane 7 homolog (yeast) (TOMM7),mRNA [NM_019059] NM_001907 CTRL Homo sapiens chymotrypsin-like (CTRL),mRNA [NM_001907] XM_372331 NKX1-2 PREDICTED: Homo sapiens NK1transcription factor related, locus 2 (Drosophila) (NKX1-2), mRNA[XM_372331] ENST00000237840 hCG_1642354 PREDICTED: Homo sapiens similarto 60S ribosomal protein L23a (LOC341511), mRNA [XM_292109] XR_015402LOC731170 PREDICTED: Homo sapiens similar to eukaryotic translationelongation factor 1 alpha 2 (LOC731170), mRNA [XR_015402] NM_138693KLF14 Homo sapiens Kruppel-like factor 14 (KLF14), mRNA [NM_138693]NM_033260 FOXQ1 Homo sapiens forkhead box Q1 (FOXQ1), mRNA [NM_033260]XM_926013 LOC642398 PREDICTED: Homo sapiens hypothetical LOC642398,transcript variant 1 (LOC642398), mRNA [XM_926013] NM_015417 C20orf28Homo sapiens chromosome 20 open reading frame 28 (C20orf28), mRNA[NM_015417] XR_018155 LOC643013 PREDICTED: Homo sapiens similar tolaminin receptor 1 (ribosomal protein SA) (LOC643013), mRNA [XR_018155]NM_004137 KCNMB1 Homo sapiens potassium large conductancecalcium-activated channel, subfamily M, beta member 1 (KCNMB1), mRNA[NM_004137] NM_198904 GABRG2 Homo sapiens gamma-aminobutyric acid (GABA)A receptor, gamma 2 (GABRG2), transcript variant 1, mRNA [NM_198904]NM_013373 ZDHHC8 Homo sapiens zinc finger, DHHC-type containing 8(ZDHHC8), mRNA [NM_013373] AA627135 AA627135 nq71a04.s1 NCI_CGAP_Pr22Homo sapiens cDNA clone IMAGE: 1157742 3′ similar to SW: R13A_HUMANP40429 60S RIBOSOMAL PROTEIN L13A;, mRNA sequence [AA627135] NM_000661RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcript variant 1,mRNA [NM_000661] XR_018553 LOC648294 PREDICTED: Homo sapienshypothetical LOC648294 (LOC648294), mRNA [XR_018553] NM_033060 KRTAP4-10Homo sapiens keratin associated protein 4-10 (KRTAP4-10), mRNA[NM_033060] NM_000984 RPL23A Homo sapiens ribosomal protein L23a(RPL23A), mRNA [NM_000984] BC002431 B4GALT2 Homo sapiens cDNA cloneIMAGE: 3347310, containing frame- shift errors. [BC002431] NM_000983RPL22 Homo sapiens ribosomal protein L22 (RPL22), mRNA [NM_000983]XM_927514 LOC644357 PREDICTED: Homo sapiens similar to Elongation factor1-delta (EF-1-delta) (Antigen NY-CO-4) (LOC644357), mRNA [XM_927514]NM_001014373 C19orf31 Homo sapiens chromosome 19 open reading frame 31(C19orf31), mRNA [NM_001014373] XR_018133 LOC389404 PREDICTED: Homosapiens similar to 60S ribosomal protein L9 (LOC389404), mRNA[XR_018133] NM_003202 TCF7 Homo sapiens transcription factor 7 (T-cellspecific, HMG-box) (TCF7), transcript variant 1, mRNA [NM_003202]A_24_P213073 A_24_P213073 Unknown THC2615996 THC2615996 UnknownNM_016337 EVL Homo sapiens Enah/Vasp-like (EVL), mRNA [NM_016337]NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1alpha 1 (EEF1A1), mRNA [NM_001402] NM_015355 SUZ12 Homo sapienssuppressor of zeste 12 homolog (Drosophila) (SUZ12), mRNA [NM_015355]ENST00000332289 ENST00000332289 PREDICTED: Homo sapiens similar to 40Sribosomal protein SA (p40) (34 [XR_019580] CR627135 CR627135 Homosapiens mRNA; cDNA DKFZp779J0122 (from clone DKFZp779J0122). [CR627135]THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homo sapiens} (exp= −1; wgp = 0; cg = 0), partial (42%) [THC2533996] A_24_P714750A_24_P714750 Unknown ENST00000333351 ENST00000333351 PREDICTED: Homosapiens hypothetical LOC391504 (LOC391504), mRNA [XR_018627] NM_178230PPIAL4 Homo sapiens peptidylprolyl isomerase A (cyclophilin A)-like 4(PPIAL4), mRNA [NM_178230] NM_003754 EIF3S5 Homo sapiens eukaryotictranslation initiation factor 3, subunit 5 epsilon, 47 kDa (EIF3S5),mRNA [NM_003754] NM_001212 C1QBP Homo sapiens complement component 1, qsubcomponent binding protein (C1QBP), nuclear gene encodingmitochondrial protein, mRNA [NM_001212] NM_006597 HSPA8 Homo sapiensheat shock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA[NM_006597]

TABLE 6 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻⁴and the log-median-ratio being at least “0.8” or above, or being atleast “−0.8” or below. GenBank Accession GeneName DescriptionNM_001039567 RPS4Y2 Homo sapiens ribosomal protein S4, Y-linked 2(RPS4Y2), mRNA [NM_001039567] NM_001008 RPS4Y1 Homo sapiens ribosomalprotein S4, Y-linked 1 (RPS4Y1), mRNA [NM_001008] NM_015646 RAP1B Homosapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant1, mRNA [NM_015646] NM_033251 RPL13 Homo sapiens ribosomal protein L13(RPL13), transcript variant 2, mRNA [NM_033251] NM_001803 CD52 Homosapiens CD52 molecule (CD52), mRNA [NM_001803] NM_006597 HSPA8 Homosapiens heat shock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA[NM_006597] NM_001402 EEF1A1 Homo sapiens eukaryotic translationelongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_001030 RPS27Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA[NM_001030] XR_017498 LOC645693 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 alpha 2 (LOC645693), mRNA[XR_017498] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_001778 CD48 Homosapiens CD48 molecule (CD48), mRNA [NM_001778] NM_001017 RPS13 Homosapiens ribosomal protein S13 (RPS13), mRNA [NM_001017] THC2544911THC2544911 MUSEFTU elongation factor Tu {Mus musculus} (exp = −1; wgp =0; cg = 0), partial (37%) [THC2544911] NM_021104 RPL41 Homo sapiensribosomal protein L41 (RPL41), transcript variant 1, mRNA [NM_021104]NM_000981 RPL19 Homo sapiens ribosomal protein L19 (RPL19), mRNA[NM_000981] NM_002300 LDHB Homo sapiens lactate dehydrogenase B (LDHB),mRNA [NM_002300] NM_033251 RPL13 Homo sapiens ribosomal protein L13(RPL13), transcript variant 2, mRNA [NM_033251] NM_003973 RPL14 Homosapiens ribosomal protein L14 (RPL14), transcript variant 2, mRNA[NM_003973] NM_000978 RPL23 Homo sapiens ribosomal protein L23 (RPL23),mRNA [NM_000978] A_24_P392195 A_24_P392195 Unknown NM_001028 RPS25 Homosapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] NM_001032 RPS29Homo sapiens ribosomal protein S29 (RPS29), transcript variant 1, mRNA[NM_001032] XR_017260 LOC646710 PREDICTED: Homo sapiens hypotheticalLOC646710 (LOC646710), mRNA [XR_017260] A_24_P333112 A_24_P333112Unknown XR_017294 LOC646949 PREDICTED: Homo sapiens similar to ribosomalprotein L23 (LOC646949), mRNA [XR_017294] NM_002085 GPX4 Homo sapiensglutathione peroxidase 4 (phospholipid hydroperoxidase) (GPX4),transcript variant 1, mRNA [NM_002085] XR_015548 LOC729449 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC729449), mRNA[XR_015548] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_001402 EEF1A1 Homosapiens eukaryotic translation elongation factor 1 alpha 1 (EEF1A1),mRNA [NM_001402] NM_001568 EIF3S6 Homo sapiens eukaryotic translationinitiation factor 3, subunit 6 48 kDa (EIF3S6), mRNA [NM_001568]A_32_P128781 A_32_P128781 Unknown ENST00000312528 ENST00000312528Unknown NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongationfactor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_025228 TRAF3IP3 Homosapiens TRAF3 interacting protein 3 (TRAF3IP3), mRNA [NM_025228]A_24_P332292 A_24_P332292 Unknown NM_198969 AES Homo sapiensamino-terminal enhancer of split (AES), transcript variant 1, mRNA[NM_198969] NM_000989 RPL30 Homo sapiens ribosomal protein L30 (RPL30),mRNA [NM_000989] A_24_P878388 A_24_P878388 Unknown XR_016879 LOC388401PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC388401),mRNA [XR_016879] NM_000967 RPL3 Homo sapiens ribosomal protein L3(RPL3), transcript variant 1, mRNA [NM_000967] NM_000967 RPL3 Homosapiens ribosomal protein L3 (RPL3), transcript variant 1, mRNA[NM_000967] A_24_P84408 A_24_P84408 Unknown NM_000661 RPL9 Homo sapiensribosomal protein L9 (RPL9), transcript variant 1, mRNA [NM_000661]NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcriptvariant 1, mRNA [NM_000661] A_24_P650893 A_24_P650893 UnknownA_24_P298238 A_24_P298238 Unknown THC2541331 THC2541331 HSU02032ribosomal protein L23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0),partial (71%) [THC2541331] XR_018025 LOC641790 PREDICTED: Homo sapienssimilar to ribosomal protein L31 (LOC641790), mRNA [XR_018025] BC018140RPS21 Homo sapiens ribosomal protein S21, mRNA (cDNA clone MGC: 9438IMAGE: 3903320), complete cds. [BC018140] ENST00000308989ENST00000308989 PREDICTED: Homo sapiens similar to ribosomal protein L31(LOC729005), mRNA [XM_001133428] A_24_P212726 A_24_P212726 UnknownNM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25), mRNA[NM_001028] XR_015402 LOC731170 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 alpha 2 (LOC731170), mRNA[XR_015402] A_24_P340886 A_24_P340886 Unknown XR_019376 LOC285260PREDICTED: Homo sapiens similar to ribosomal protein L31 (LOC285260),mRNA [XR_019376] ENST00000359449 ENST00000359449 Sequence 237 fromPatent WO0220754. [AX721277] XR_018975 LOC389644 PREDICTED: Homo sapienssimilar to ribosomal protein L5 (LOC389644), mRNA [XR_018975]A_24_P505981 A_24_P505981 Unknown ENST00000240349 NACA3P PREDICTED: Homosapiens similar to nascent polypeptide- associated complex alphapolypeptide (LOC389240), mRNA [XM_371715] A_24_P221375 A_24_P221375Unknown NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A),mRNA [NM_000984] XR_018231 LOC648027 PREDICTED: Homo sapiens similar toElongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) (LOC648027), mRNA[XR_018231] NM_013234 EIF3S12 Homo sapiens eukaryotic translationinitiation factor 3, subunit 12 (EIF3S12), mRNA [NM_013234] NM_001861COX4I1 Homo sapiens cytochrome c oxidase subunit IV isoform 1 (COX4I1),mRNA [NM_001861] XR_019544 LOC652890 PREDICTED: Homo sapiens similar to60S ribosomal protein L7 (LOC652890), mRNA [XR_019544] NM_000982 RPL21Homo sapiens ribosomal protein L21 (RPL21), mRNA [NM_000982]A_23_P210285 A_23_P210285 Unknown XR_019361 LOC442260 PREDICTED: Homosapiens similar to 60S ribosomal protein L23a (LOC442260), mRNA[XR_019361] A_24_P289884 A_24_P289884 Unknown A_24_P135242 A_24_P135242Unknown NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14),transcript variant 2, mRNA [NM_003973] XR_019386 LOC652558 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC652558), mRNA[XR_019386] THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (42%) [THC2533996]NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA[NM_000984] NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2(CDC42SE2), transcript variant 1, mRNA [NM_020240] NM_007104 RPL10A Homosapiens ribosomal protein L10a (RPL10A), mRNA [NM_007104] XR_015944LOC731681 PREDICTED: Homo sapiens similar to 60S ribosomal protein L9(LOC731681), mRNA [XR_015944] NM_001404 EEF1G Homo sapiens eukaryotictranslation elongation factor 1 gamma (EEF1G), mRNA [NM_001404]NM_021103 TMSB10 Homo sapiens thymosin, beta 10 (TMSB10), mRNA[NM_021103] NM_001011 RPS7 Homo sapiens ribosomal protein S7 (RPS7),mRNA [NM_001011] NM_016270 KLF2 Homo sapiens Kruppel-like factor 2(lung) (KLF2), mRNA [NM_016270] NM_015414 RPL36 Homo sapiens ribosomalprotein L36 (RPL36), transcript variant 2, mRNA [NM_015414] XR_018222RPL31P4 PREDICTED: Homo sapiens ribosomal protein L31 pseudogene 4(RPL31P4), mRNA [XR_018222] BC028083 TRBV5-4 Homo sapiens T cellreceptor beta variable 5-4, mRNA (cDNA clone MGC: 40031 IMAGE: 5217067),complete cds. [BC028083] NM_033625 RPL34 Homo sapiens ribosomal proteinL34 (RPL34), transcript variant 2, mRNA [NM_033625] NM_000996 RPL35AHomo sapiens ribosomal protein L35a (RPL35A), mRNA [NM_000996]A_24_P144163 A_24_P144163 Unknown A_24_P238427 A_24_P238427 UnknownAK092748 RP3-377H14.5 Homo sapiens cDNA FLJ35429 fis, cloneSMINT2002126. [AK092748] THC2560098 THC2560098 S35960 C-terminal {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (64%) [THC2560098]A_24_P324224 A_24_P324224 Unknown NM_203477 MGC70863 Homo sapienssimilar to RPL23AP7 protein (MGC70863), transcript variant 1, mRNA[NM_203477] XR_019277 LOC391719 PREDICTED: Homo sapiens similar toribosomal protein L19 (LOC391719), mRNA [XR_019277] AK098605 AK098605Homo sapiens cDNA FLJ25739 fis, clone TST05834. [AK098605] A_24_P127442A_24_P127442 Unknown NM_153236 GIMAP7 Homo sapiens GTPase, IMAP familymember 7 (GIMAP7), mRNA [NM_153236] NR_001577 NME2P1 Homo sapiensnon-metastatic cells 2, protein (NM23B) expressed in, pseudogene 1(NME2P1) on chromosome 12 [NR_001577] XR_015767 LOC731224 PREDICTED:Homo sapiens similar to 60S ribosomal protein L9 (LOC731224), mRNA[XR_015767] AK124741 AK124741 Homo sapiens cDNA FLJ42751 fis, cloneBRAWH3000491, moderately similar to 40S ribosomal protein S12.[AK124741] NM_000984 RPL23A Homo sapiens ribosomal protein L23a(RPL23A), mRNA [NM_000984] XM_001125895 LOC730452 PREDICTED: Homosapiens similar to 60S ribosomal protein L7 (LOC730452), mRNA[XM_001125895] NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3),transcript variant 1, mRNA [NM_000967] XR_018341 LOC390413 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC390413), mRNA[XR_018341] XR_018054 LOC392878 PREDICTED: Homo sapiens hypotheticalLOC392878 (LOC392878), mRNA [XR_018054] NM_006013 RPL10 Homo sapiensribosomal protein L10 (RPL10), mRNA [NM_006013] ENST00000332696ENST00000332696 similar to 60S ribosomal protein L23a (LOC644384), mRNA[Source: RefSeq_dna; Acc: XR_017413] [ENST00000332696] A_24_P204474A_24_P204474 Unknown A_32_P208856 A_32_P208856 Unknown NM_001404 EEF1GHomo sapiens eukaryotic translation elongation factor 1 gamma (EEF1G),mRNA [NM_001404] THC2506377 THC2506377 HSU02032 ribosomal protein L23a{Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (92%) [THC2506377]NM_080746 RPL10L Homo sapiens ribosomal protein L10-like (RPL10L), mRNA[NM_080746] NM_000986 RPL24 Homo sapiens ribosomal protein L24 (RPL24),mRNA [NM_000986] XM_928025 LOC644937 PREDICTED: Homo sapiens similar to60S ribosomal protein L10 (QM protein) (Tumor suppressor QM) (Lamininreceptor homolog) (LOC644937), mRNA [XM_928025] XM_930195 hCG_18290PREDICTED: Homo sapiens similar to 60S ribosomal protein L32(LOC644907), mRNA [XM_930195] NM_001080544 LOC653314 Homo sapienssimilar to ribosomal protein L19 (LOC653314), mRNA [NM_001080544]ENST00000333351 ENST00000333351 PREDICTED: Homo sapiens hypotheticalLOC391504 (LOC391504), mRNA [XR_018627] A_24_P212654 A_24_P212654Unknown XR_018509 LOC391701 PREDICTED: Homo sapiens similar to ribosomalprotein S23 (LOC391701), mRNA [XR_018509] NM_000979 RPL18 Homo sapiensribosomal protein L18 (RPL18), mRNA [NM_000979] NM_019059 TOMM7 Homosapiens translocase of outer mitochondrial membrane 7 homolog (yeast)(TOMM7), mRNA [NM_019059] A_24_P392436 A_24_P392436 UnknownENST00000361800 ENST00000361800 Unknown A_24_P32207 A_24_P32207 UnknownNM_000979 RPL18 Homo sapiens ribosomal protein L18 (RPL18), mRNA[NM_000979] A_24_P384411 A_24_P384411 Unknown NM_002258 KLRB1 Homosapiens killer cell lectin-like receptor subfamily B, member 1 (KLRB1),mRNA [NM_002258] NM_001023 RPS20 Homo sapiens ribosomal protein S20(RPS20), mRNA [NM_001023] A_24_P32836 A_24_P32836 Unknown NM_019059TOMM7 Homo sapiens translocase of outer mitochondrial membrane 7 homolog(yeast) (TOMM7), mRNA [NM_019059] A_24_P350008 A_24_P350008 UnknownXR_018553 LOC648294 PREDICTED: Homo sapiens hypothetical LOC648294(LOC648294), mRNA [XR_018553] XR_018303 LOC648378 PREDICTED: Homosapiens similar to ribosomal protein S14 (LOC648378), mRNA [XR_018303]NM_032378 EEF1D Homo sapiens eukaryotic translation elongation factor 1delta (guanine nucleotide exchange protein) (EEF1D), transcript variant1, mRNA [NM_032378] A_24_P118874 A_24_P118874 Unknown NM_001014 RPS10Homo sapiens ribosomal protein S10 (RPS10), mRNA [NM_001014] NR_000029RPL23AP7 Homo sapiens ribosomal protein L23a pseudogene 7 (RPL23AP7) onchromosome 2 [NR_000029] NM_002818 PSME2 Homo sapiens proteasome(prosome, macropain) activator subunit 2 (PA28 beta) (PSME2), mRNA[NM_002818] NM_016337 EVL Homo sapiens Enah/Vasp-like (EVL), mRNA[NM_016337] ENST00000237840 hCG_1642354 PREDICTED: Homo sapiens similarto 60S ribosomal protein L23a (LOC341511), mRNA [XM_292109] NM_001404EEF1G Homo sapiens eukaryotic translation elongation factor 1 gamma(EEF1G), mRNA [NM_001404] XR_018970 LOC391140 PREDICTED: Homo sapienssimilar to ribosomal protein L13 (LOC391140), mRNA [XR_018970] NM_000969RPL5 Homo sapiens ribosomal protein L5 (RPL5), mRNA [NM_000969]THC2494410 THC2494410 2113200F ribosomal protein S9. {Homo sapiens} (exp= −1; wgp = −1; cg = −1), complete [THC2494410] A_24_P93452 A_24_P93452Unknown A_24_P366457 A_24_P366457 Unknown NM_000661 RPL9 Homo sapiensribosomal protein L9 (RPL9), transcript variant 1, mRNA [NM_000661]XR_016930 LOC645412 PREDICTED: Homo sapiens similar to 40S ribosomalprotein S16 (LOC645412), mRNA [XR_016930] NM_001018 RPS15 Homo sapiensribosomal protein S15 (RPS15), mRNA [NM_001018] ENST00000359659ENST00000359659 Q8BT90_MOUSE (Q8BT90) 10, 11 days embryo whole bodycDNA, RIKEN full-length enriched library, clone: 2810021H19 product:ribosomal protein S17, full insert sequence. (Fragment), partial (98%)[THC2555910] A_24_P93052 A_24_P93052 Unknown NM_015853 LOC51035 Homosapiens SAPK substrate protein 1 (LOC51035), mRNA [NM_015853]A_24_P410070 A_24_P410070 Unknown A_24_P170103 A_24_P170103 UnknownAX721252 AX721252 Sequence 212 from Patent WO0220754. [AX721252]A_24_P33213 A_24_P33213 Unknown XR_018720 LOC392206 PREDICTED: Homosapiens similar to ribosomal protein L10a (LOC392206), mRNA [XR_018720]A_24_P341176 A_24_P341176 Unknown NM_000971 RPL7 Homo sapiens ribosomalprotein L7 (RPL7), mRNA [NM_000971] XR_018133 LOC389404 PREDICTED: Homosapiens similar to 60S ribosomal protein L9 (LOC389404), mRNA[XR_018133] NM_005594 NACA Homo sapiens nascent-polypeptide-associatedcomplex alpha polypeptide (NACA), mRNA [NM_005594] NM_006013 RPL10 Homosapiens ribosomal protein L10 (RPL10), mRNA [NM_006013] A_24_P101271A_24_P101271 Unknown A_24_P264549 A_24_P264549 Unknown THC2782843THC2782843 RL18A_HUMAN (Q02543) 60S ribosomal protein L18a, partial(89%) [THC2782843] XM_379885 hCG_2023776 PREDICTED: Homo sapiens similarto Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizingprotein) (Single-strand binding protein) (hnRNP core protein A1) (HDP-1)(Topoisomerase- inhibitor suppressed) (LOC402562), mRNA [XM_379885]NM_152219 GJC1 Homo sapiens gap junction protein, chi 1, 31.9 kDa(GJC1), mRNA [NM_152219] ENST00000323800 ENST00000323800 CDNA FLJ25155fis, clone CBR07976. [Source: Uniprot/SPTREMBL; Acc: Q96LR6][ENST00000323800] THC2737361 THC2737361 Q2IMJ3_ANADE (Q2IMJ3) LigA,partial (5%) [THC2737361] THC2718728 THC2718728 Unknown AA418814AA418814 AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA cloneIMAGE: 767978 3′, mRNA sequence [AA418814]

TABLE 7 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻⁵and the log-median-ratio being at least “0.585” or above, or being atleast “−0.585” or below. GenBank Accession GeneName DescriptionNM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8 (HSPA8),transcript variant 1, mRNA [NM_006597] NM_001402 EEF1A1 Homo sapienseukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA[NM_001402] XR_016879 LOC388401 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7 (LOC388401), mRNA [XR_016879] XR_015402 LOC731170PREDICTED: Homo sapiens similar to eukaryotic translation elongationfactor 1 alpha 2 (LOC731170), mRNA [XR_015402] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] THC2533996THC2533996 HSU09954 ribosomal protein L9 {Homo sapiens} (exp = −1; wgp =0; cg = 0), partial (42%) [THC2533996] NM_203477 MGC70863 Homo sapienssimilar to RPL23AP7 protein (MGC70863), transcript variant 1, mRNA[NM_203477] NM_001404 EEF1G Homo sapiens eukaryotic translationelongation factor 1 gamma (EEF1G), mRNA [NM_001404] ENST00000333351ENST00000333351 PREDICTED: Homo sapiens hypothetical LOC391504(LOC391504), mRNA [XR_018627] NM_019059 TOMM7 Homo sapiens translocaseof outer mitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA[NM_019059] XR_018553 LOC648294 PREDICTED: Homo sapiens hypotheticalLOC648294 (LOC648294), mRNA [XR_018553] NR_000029 RPL23AP7 Homo sapiensribosomal protein L23a pseudogene 7 (RPL23AP7) on chromosome 2[NR_000029] NM_016337 EVL Homo sapiens Enah/Vasp-like (EVL), mRNA[NM_016337] ENST00000237840 hCG_1642354 PREDICTED: Homo sapiens similarto 60S ribosomal protein L23a (LOC341511), mRNA [XM_292109] NM_000661RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcript variant 1,mRNA [NM_000661] A_24_P93052 A_24_P93052 Unknown XR_018133 LOC389404PREDICTED: Homo sapiens similar to 60S ribosomal protein L9 (LOC389404),mRNA [XR_018133] BC030568 LOC376693 Homo sapiens hypothetical LOC376693,mRNA (cDNA clone MGC: 45392 IMAGE: 5526694), complete cds. [BC030568]XR_018155 LOC643013 PREDICTED: Homo sapiens similar to laminin receptor1 (ribosomal protein SA) (LOC643013), mRNA [XR_018155] A_24_P213073A_24_P213073 Unknown NM_000983 RPL22 Homo sapiens ribosomal protein L22(RPL22), mRNA [NM_000983] NM_003202 TCF7 Homo sapiens transcriptionfactor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein(MGC70863), transcript variant 1, mRNA [NM_203477] AA627135 AA627135nq71a04.s1 NCI_CGAP_Pr22 Homo sapiens cDNA clone IMAGE: 1157742 3′similar to SW: R13A_HUMAN P40429 60S RIBOSOMAL PROTEIN L13A;, mRNAsequence [AA627135] ENST00000303979 ENST00000303979 Unknown NM_003754EIF3S5 Homo sapiens eukaryotic translation initiation factor 3, subunit5 epsilon, 47 kDa (EIF3S5), mRNA [NM_003754] NM_001212 C1QBP Homosapiens complement component 1, q subcomponent binding protein (C1QBP),nuclear gene encoding mitochondrial protein, mRNA [NM_001212] XM_927514LOC644357 PREDICTED: Homo sapiens similar to Elongation factor 1-delta(EF-1-delta) (Antigen NY-CO-4) (LOC644357), mRNA [XM_927514] NM_178230PPIAL4 Homo sapiens peptidylprolyl isomerase A (cyclophilin A)-like 4(PPIAL4), mRNA [NM_178230] ENST00000332289 ENST00000332289 PREDICTED:Homo sapiens similar to 40S ribosomal protein SA (p40) (34 [XR_019580]XM_001128309 LOC730663 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L23a (LOC730663), mRNA [XM_001128309] XM_372331 NKX1-2PREDICTED: Homo sapiens NK1 transcription factor related, locus 2(Drosophila) (NKX1-2), mRNA [XM_372331] THC2718728 THC2718728 Unknown

TABLE 8 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻⁴and the log-median-ratio being at least “1” or above, or being at least“−1” or below. GenBank Accession GeneName Description NM_001039567RPS4Y2 Homo sapiens ribosomal protein S4, Y-linked 2 (RPS4Y2), mRNA[NM_001039567] NM_001008 RPS4Y1 Homo sapiens ribosomal protein S4,Y-linked 1 (RPS4Y1), mRNA [NM_001008] NM_015646 RAP1B Homo sapiensRAP1B, member of RAS oncogene family (RAP1B), transcript variant 1, mRNA[NM_015646] NM_033251 RPL13 Homo sapiens ribosomal protein L13 (RPL13),transcript variant 2, mRNA [NM_033251] NM_001803 CD52 Homo sapiens CD52molecule (CD52), mRNA [NM_001803] NM_006597 HSPA8 Homo sapiens heatshock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597]NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1alpha 1 (EEF1A1), mRNA [NM_001402] NM_001030 RPS27 Homo sapiensribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA [NM_001030]XR_017498 LOC645693 PREDICTED: Homo sapiens similar to eukaryotictranslation elongation factor 1 alpha 2 (LOC645693), mRNA [XR_017498]NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8 (HSPA8),transcript variant 1, mRNA [NM_006597] NM_001778 CD48 Homo sapiens CD48molecule (CD48), mRNA [NM_001778] NM_001017 RPS13 Homo sapiens ribosomalprotein S13 (RPS13), mRNA [NM_001017] THC2544911 THC2544911 MUSEFTUelongation factor Tu {Mus musculus} (exp = −1; wgp = 0; cg = 0), partial(37%) [THC2544911] NM_021104 RPL41 Homo sapiens ribosomal protein L41(RPL41), transcript variant 1, mRNA [NM_021104] NM_000981 RPL19 Homosapiens ribosomal protein L19 (RPL19), mRNA [NM_000981] NM_002300 LDHBHomo sapiens lactate dehydrogenase B (LDHB), mRNA [NM_002300] NM_033251RPL13 Homo sapiens ribosomal protein L13 (RPL13), transcript variant 2,mRNA [NM_033251] NM_003973 RPL14 Homo sapiens ribosomal protein L14(RPL14), transcript variant 2, mRNA [NM_003973] NM_000978 RPL23 Homosapiens ribosomal protein L23 (RPL23), mRNA [NM_000978] A_24_P392195A_24_P392195 Unknown NM_001028 RPS25 Homo sapiens ribosomal protein S25(RPS25), mRNA [NM_001028] NM_001032 RPS29 Homo sapiens ribosomal proteinS29 (RPS29), transcript variant 1, mRNA [NM_001032] XR_017260 LOC646710PREDICTED: Homo sapiens hypothetical LOC646710 (LOC646710), mRNA[XR_017260] A_24_P333112 A_24_P333112 Unknown XR_017294 LOC646949PREDICTED: Homo sapiens similar to ribosomal protein L23 (LOC646949),mRNA [XR_017294] NM_002085 GPX4 Homo sapiens glutathione peroxidase 4(phospholipid hydroperoxidase) (GPX4), transcript variant 1, mRNA[NM_002085] XR_015548 LOC729449 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7 (LOC729449), mRNA [XR_015548] NM_006597 HSPA8 Homosapiens heat shock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA[NM_006597] NM_001402 EEF1A1 Homo sapiens eukaryotic translationelongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_001568 EIF3S6Homo sapiens eukaryotic translation initiation factor 3, subunit 6 48kDa (EIF3S6), mRNA [NM_001568] A_32_P128781 A_32_P128781 UnknownENST00000312528 ENST00000312528 Unknown NM_001402 EEF1A1 Homo sapienseukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA[NM_001402] NM_025228 TRAF3IP3 Homo sapiens TRAF3 interacting protein 3(TRAF3IP3), mRNA [NM_025228] A_24_P332292 A_24_P332292 Unknown NM_198969AES Homo sapiens amino-terminal enhancer of split (AES), transcriptvariant 1, mRNA [NM_198969] NM_000989 RPL30 Homo sapiens ribosomalprotein L30 (RPL30), mRNA [NM_000989] A_24_P878388 A_24_P878388 UnknownXR_016879 LOC388401 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L7 (LOC388401), mRNA [XR_016879] NM_000967 RPL3 Homo sapiensribosomal protein L3 (RPL3), transcript variant 1, mRNA [NM_000967]NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcriptvariant 1, mRNA [NM_000967] A_24_P84408 A_24_P84408 Unknown NM_000661RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcript variant 1,mRNA [NM_000661] NM_000661 RPL9 Homo sapiens ribosomal protein L9(RPL9), transcript variant 1, mRNA [NM_000661] A_24_P650893 A_24_P650893Unknown A_24_P298238 A_24_P298238 Unknown THC2541331 THC2541331 HSU02032ribosomal protein L23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0),partial (71%) [THC2541331] XR_018025 LOC641790 PREDICTED: Homo sapienssimilar to ribosomal protein L31 (LOC641790), mRNA [XR_018025] BC018140RPS21 Homo sapiens ribosomal protein S21, mRNA (cDNA clone MGC: 9438IMAGE: 3903320), complete cds. [BC018140] ENST00000308989ENST00000308989 PREDICTED: Homo sapiens similar to ribosomal protein L31(LOC729005), mRNA [XM_001133428] A_24_P212726 A_24_P212726 UnknownNM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25), mRNA[NM_001028] XR_015402 LOC731170 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 alpha 2 (LOC731170), mRNA[XR_015402] A_24_P340886 A_24_P340886 Unknown XR_019376 LOC285260PREDICTED: Homo sapiens similar to ribosomal protein L31 (LOC285260),mRNA [XR_019376] ENST00000359449 ENST00000359449 Sequence 237 fromPatent WO0220754. [AX721277] XR_018975 LOC389644 PREDICTED: Homo sapienssimilar to ribosomal protein L5 (LOC389644), mRNA [XR_018975]A_24_P505981 A_24_P505981 Unknown ENST00000240349 NACA3P PREDICTED: Homosapiens similar to nascent polypeptide- associated complex alphapolypeptide (LOC389240), mRNA [XM_371715] A_24_P221375 A_24_P221375Unknown NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A),mRNA [NM_000984] XR_018231 LOC648027 PREDICTED: Homo sapiens similar toElongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) (LOC648027), mRNA[XR_018231] NM_013234 EIF3S12 Homo sapiens eukaryotic translationinitiation factor 3, subunit 12 (EIF3S12), mRNA [NM_013234] NM_001861COX4I1 Homo sapiens cytochrome c oxidase subunit IV isoform 1 (COX4I1),mRNA [NM_001861] XR_019544 LOC652890 PREDICTED: Homo sapiens similar to60S ribosomal protein L7 (LOC652890), mRNA [XR_019544] NM_000982 RPL21Homo sapiens ribosomal protein L21 (RPL21), mRNA [NM_000982]A_23_P210285 A_23_P210285 Unknown XR_019361 LOC442260 PREDICTED: Homosapiens similar to 60S ribosomal protein L23a (LOC442260), mRNA[XR_019361] A_24_P289884 A_24_P289884 Unknown A_24_P135242 A_24_P135242Unknown NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14),transcript variant 2, mRNA [NM_003973] XR_019386 LOC652558 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC652558), mRNA[XR_019386] THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (42%) [THC2533996]NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA[NM_000984] NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2(CDC42SE2), transcript variant 1, mRNA [NM_020240] NM_007104 RPL10A Homosapiens ribosomal protein L10a (RPL10A), mRNA [NM_007104] XR_015944LOC731681 PREDICTED: Homo sapiens similar to 60S ribosomal protein L9(LOC731681), mRNA [XR_015944] NM_001404 EEF1G Homo sapiens eukaryotictranslation elongation factor 1 gamma (EEF1G), mRNA [NM_001404]NM_021103 TMSB10 Homo sapiens thymosin, beta 10 (TMSB10), mRNA[NM_021103] NM_001011 RPS7 Homo sapiens ribosomal protein S7 (RPS7),mRNA [NM_001011] NM_016270 KLF2 Homo sapiens Kruppel-like factor 2(lung) (KLF2), mRNA [NM_016270] NM_015414 RPL36 Homo sapiens ribosomalprotein L36 (RPL36), transcript variant 2, mRNA [NM_015414] XR_018222RPL31P4 PREDICTED: Homo sapiens ribosomal protein L31 pseudogene 4(RPL31P4), mRNA [XR_018222] BC028083 TRBV5-4 Homo sapiens T cellreceptor beta variable 5-4, mRNA (cDNA clone MGC: 40031 IMAGE: 5217067),complete cds. [BC028083] NM_033625 RPL34 Homo sapiens ribosomal proteinL34 (RPL34), transcript variant 2, mRNA [NM_033625] NM_000996 RPL35AHomo sapiens ribosomal protein L35a (RPL35A), mRNA [NM_000996]A_24_P144163 A_24_P144163 Unknown A_24_P238427 A_24_P238427 UnknownAK092748 RP3-377H14.5 Homo sapiens cDNA FLJ35429 fis, cloneSMINT2002126. [AK092748] THC2560098 THC2560098 S35960 C-terminal {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (64%) [THC2560098]A_24_P324224 A_24_P324224 Unknown NM_203477 MGC70863 Homo sapienssimilar to RPL23AP7 protein (MGC70863), transcript variant 1, mRNA[NM_203477] XR_019277 LOC391719 PREDICTED: Homo sapiens similar toribosomal protein L19 (LOC391719), mRNA [XR_019277] AK098605 AK098605Homo sapiens cDNA FLJ25739 fis, clone TST05834. [AK098605] A_24_P127442A_24_P127442 Unknown NM_153236 GIMAP7 Homo sapiens GTPase, IMAP familymember 7 (GIMAP7), mRNA [NM_153236] NR_001577 NME2P1 Homo sapiensnon-metastatic cells 2, protein (NM23B) expressed in, pseudogene 1(NME2P1) on chromosome 12 [NR_001577] XR_015767 LOC731224 PREDICTED:Homo sapiens similar to 60S ribosomal protein L9 (LOC731224), mRNA[XR_015767] AK124741 AK124741 Homo sapiens cDNA FLJ42751 fis, cloneBRAWH3000491, moderately similar to 40S ribosomal protein S12.[AK124741] NM_000984 RPL23A Homo sapiens ribosomal protein L23a(RPL23A), mRNA [NM_000984] XM_001125895 LOC730452 PREDICTED: Homosapiens similar to 60S ribosomal protein L7 (LOC730452), mRNA[XM_001125895] NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3),transcript variant 1, mRNA [NM_000967] XR_018341 LOC390413 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC390413), mRNA[XR_018341] XR_018054 LOC392878 PREDICTED: Homo sapiens hypotheticalLOC392878 (LOC392878), mRNA [XR_018054] NM_006013 RPL10 Homo sapiensribosomal protein L10 (RPL 10), mRNA [NM_006013] ENST00000332696ENST00000332696 similar to 60S ribosomal protein L23a (LOC644384), mRNA[Source: RefSeq_dna; Acc: XR_017413] [ENST00000332696] A_24_P204474A_24_P204474 Unknown A_32_P208856 A_32_P208856 Unknown NM_001404 EEF1GHomo sapiens eukaryotic translation elongation factor 1 gamma (EEF1G),mRNA [NM_001404] THC2506377 THC2506377 HSU02032 ribosomal protein L23a{Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (92%) [THC2506377]NM_080746 RPL10L Homo sapiens ribosomal protein L10-like (RPL10L), mRNA[NM_080746] NM_000986 RPL24 Homo sapiens ribosomal protein L24 (RPL24),mRNA [NM_000986] XM_928025 LOC644937 PREDICTED: Homo sapiens similar to60S ribosomal protein L10 (QM protein) (Tumor suppressor QM) (Lamininreceptor homolog) (LOC644937), mRNA [XM_928025] XM_930195 hCG_18290PREDICTED: Homo sapiens similar to 60S ribosomal protein L32(LOC644907), mRNA [XM_930195] NM_001080544 LOC653314 Homo sapienssimilar to ribosomal protein L19 (LOC653314), mRNA [NM_001080544]ENST00000333351 ENST00000333351 PREDICTED: Homo sapiens hypotheticalLOC391504 (LOC391504), mRNA [XR_018627] THC2718728 THC2718728 UnknownAA418814 AA418814 AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNAclone IMAGE: 767978 3′, mRNA sequence [AA418814]

TABLE 9 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻⁵and the log-median-ratio being below “0”. GenBank Accession GeneNameDescription NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_019059 TOMM7 Homosapiens translocase of outer mitochondrial membrane 7 homolog (yeast)(TOMM7), mRNA [NM_019059] NM_001402 EEF1A1 Homo sapiens eukaryotictranslation elongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402]NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863),transcript variant 1, mRNA [NM_203477] XR_016879 LOC388401 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC388401), mRNA[XR_016879] XR_015402 LOC731170 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 alpha 2 (LOC731170), mRNA[XR_015402] THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (42%) [THC2533996]NR_000029 RPL23AP7 Homo sapiens ribosomal protein L23a pseudogene 7(RPL23AP7) on chromosome 2 [NR_000029] NM_001404 EEF1G Homo sapienseukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] NM_000984 RPL23A Homo sapiens ribosomal protein L23a(RPL23A), mRNA [NM_000984] ENST00000333351 ENST00000333351 PREDICTED:Homo sapiens hypothetical LOC391504 (LOC391504), mRNA [XR_018627]XR_018553 LOC648294 PREDICTED: Homo sapiens hypothetical LOC648294(LOC648294), mRNA [XR_018553] BC030568 LOC376693 Homo sapienshypothetical LOC376693, mRNA (cDNA clone MGC: 45392 IMAGE: 5526694),complete cds. [BC030568] ENST00000237840 hCG_1642354 PREDICTED: Homosapiens similar to 60S ribosomal protein L23a (LOC341511), mRNA[XM_292109] A_24_P93052 A_24_P93052 Unknown NM_016337 EVL Homo sapiensEnah/Vasp-like (EVL), mRNA [NM_016337] NM_000661 RPL9 Homo sapiensribosomal protein L9 (RPL9), transcript variant 1, mRNA [NM_000661]ENST00000303979 ENST00000303979 Unknown NM_003202 TCF7 Homo sapienstranscription factor 7 (T-cell specific, HMG-box) (TCF7), transcriptvariant 1, mRNA [NM_003202] XR_018133 LOC389404 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L9 (LOC389404), mRNA [XR_018133]A_24_P213073 A_24_P213073 Unknown NM_000983 RPL22 Homo sapiens ribosomalprotein L22 (RPL22), mRNA [NM_000983] XR_018155 LOC643013 PREDICTED:Homo sapiens similar to laminin receptor 1 (ribosomal protein SA)(LOC643013), mRNA [XR_018155] NM_203477 MGC70863 Homo sapiens similar toRPL23AP7 protein (MGC70863), transcript variant 1, mRNA [NM_203477]NM_001212 C1QBP Homo sapiens complement component 1, q subcomponentbinding protein (C1QBP), nuclear gene encoding mitochondrial protein,mRNA [NM_001212] XM_001128309 LOC730663 PREDICTED: Homo sapiens similarto 60S ribosomal protein L23a (LOC730663), mRNA [XM_001128309] AA627135AA627135 nq71a04.s1 NCI_CGAP_Pr22 Homo sapiens cDNA clone IMAGE: 11577423′ similar to SW: R13A_HUMAN P40429 60S RIBOSOMAL PROTEIN L13A;, mRNAsequence [AA627135] NM_003754 EIF3S5 Homo sapiens eukaryotic translationinitiation factor 3, subunit 5 epsilon, 47 kDa (EIF3S5), mRNA[NM_003754] NM_178230 PPIAL4 Homo sapiens peptidylprolyl isomerase A(cyclophilin A)-like 4 (PPIAL4), mRNA [NM_178230] XM_927514 LOC644357PREDICTED: Homo sapiens similar to Elongation factor 1-delta(EF-1-delta) (Antigen NY-CO-4) (LOC644357), mRNA [XM_927514] NM_003202TCF7 Homo sapiens transcription factor 7 (T-cell specific, HMG-box)(TCF7), transcript variant 1, mRNA [NM_003202] ENST00000332289ENST00000332289 PREDICTED: Homo sapiens similar to 40S ribosomal proteinSA (p40) (34 [XR_019580] BC107865 LOC204010 Homo sapiens similar to 40Sribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinomalaminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associatedprotein MGr1- Ag), mRNA (cDNA clone MGC: 104447 IMAGE: 4095371),complete cds . . . NM_203477 MGC70863 Homo sapiens similar to RPL23AP7protein (MGC70863), transcript variant 1, mRNA [NM_203477] NM_001040437C6orf48 Homo sapiens chromosome 6 open reading frame 48 (C6orf48),transcript variant 1, mRNA [NM_001040437] BC006438 BC006438 Homo sapienscDNA clone MGC: 13162 IMAGE: 3010103, complete cds. [BC006438]

TABLE 10 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻⁵and the log-median-ratio being above “0”. GenBank Accession GeneNameDescription NM_001082575 HRNBP3 Homo sapiens hypothetical proteinLOC146713 (HRNBP3), mRNA [NM_001082575] NM_015355 SUZ12 Homo sapienssuppressor of zeste 12 homolog (Drosophila) (SUZ12), mRNA [NM_015355]NM_001014373 C19orf31 Homo sapiens chromosome 19 open reading frame 31(C19orf31), mRNA [NM_001014373] NM_004137 KCNMB1 Homo sapiens potassiumlarge conductance calcium-activated channel, subfamily M, beta member 1(KCNMB1), mRNA [NM_004137] CR627135 CR627135 Homo sapiens mRNA; cDNADKFZp779J0122 (from clone DKFZp779J0122). [CR627135] NM_198904 GABRG2Homo sapiens gamma-aminobutyric acid (GABA) A receptor, gamma 2(GABRG2), transcript variant 1, mRNA [NM_198904] NM_001907 CTRL Homosapiens chymotrypsin-like (CTRL), mRNA [NM_001907] XM_926013 LOC642398PREDICTED: Homo sapiens hypothetical LOC642398, transcript variant 1(LOC642398), mRNA [XM_926013] NM_015417 C20orf28 Homo sapiens chromosome20 open reading frame 28 (C20orf28), mRNA [NM_015417] BC002431 B4GALT2Homo sapiens cDNA clone IMAGE: 3347310, containing frame-shift errors.[BC002431] NM_013373 ZDHHC8 Homo sapiens zinc finger, DHHC-typecontaining 8 (ZDHHC8), mRNA [NM_013373] A_24_P714750 A_24_P714750Unknown NM_138693 KLF14 Homo sapiens Kruppel-like factor 14 (KLF14),mRNA [NM_138693] NM_033060 KRTAP4-10 Homo sapiens keratin associatedprotein 4-10 (KRTAP4-10), mRNA [NM_033060] NM_033260 FOXQ1 Homo sapiensforkhead box Q1 (FOXQ1), mRNA [NM_033260] THC2615996 THC2615996 UnknownXM_372331 NKX1-2 PREDICTED: Homo sapiens NK1 transcription factorrelated, locus 2 (Drosophila) (NKX1-2), mRNA [XM_372331] NM_001214C16orf3 Homo sapiens chromosome 16 open reading frame 3 (C16orf3), mRNA[NM_001214] THC2718728 THC2718728 Unknown

TABLE 11 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻⁴.GenBank Accession Gene Name Description NM_000978 RPL23 Homo sapiensribosomal protein L23 (RPL23), mRNA [NM_000978] NM_000979 RPL18 Homosapiens ribosomal protein L18 (RPL18), mRNA [NM_000979] A_32_P230059A_32_P230059 Unknown A_24_P144163 A_24_P144163 Unknown NM_013328 PYCR2Homo sapiens pyrroline-5-carboxylate reductase family, member 2 (PYCR2),mRNA [NM_013328] A_32_P128781 A_32_P128781 Unknown THC2718728 THC2718728Unknown NM_002085 GPX4 Homo sapiens glutathione peroxidase 4(phospholipid hydroperoxidase) (GPX4), transcript variant 1, mRNA[NM_002085] NM_000996 RPL35A Homo sapiens ribosomal protein L35a(RPL35A), mRNA [NM_000996] ENST00000333650 ENST00000333650 PREDICTED:Homo sapiens similar to 60S ribosomal protein L14 (CAG-ISL 7)(LOC730747), mRNA [XR_015398] CR594528 CR594528 full-length cDNA cloneCS0DM002YC17 of Fetal liver of Homo sapiens (human) [CR594528]A_32_P11425 A_32_P11425 Unknown NM_001028 RPS25 Homo sapiens ribosomalprotein S25 (RPS25), mRNA [NM_001028] NM_025004 CCDC15 Homo sapienscoiled-coil domain containing 15 (CCDC15), mRNA [NM_025004] A_24_P333112A_24_P333112 Unknown NM_001803 CD52 Homo sapiens CD52 molecule (CD52),mRNA [NM_001803] NM_000984 RPL23A Homo sapiens ribosomal protein L23a(RPL23A), mRNA [NM_000984] NM_001568 EIF3S6 Homo sapiens eukaryotictranslation initiation factor 3, subunit 6 48 kDa (EIF3S6), mRNA[NM_001568] NM_001032 RPS29 Homo sapiens ribosomal protein S29 (RPS29),transcript variant 1, mRNA [NM_001032] NM_175863 ARID1B Homo sapiens ATrich interactive domain 1B (SWI1-like) (ARID1B), transcript variant 3,mRNA [NM_175863] NM_030915 LBH Homo sapiens limb bud and heartdevelopment homolog (mouse) (LBH), mRNA [NM_030915] NM_001014 RPS10 Homosapiens ribosomal protein S10 (RPS10), mRNA [NM_001014] ENST00000312528ENST00000312528 Unknown NM_015414 RPL36 Homo sapiens ribosomal proteinL36 (RPL36), transcript variant 2, mRNA [NM_015414] CR933606 C20orf80Homo sapiens mRNA; cDNA DKFZp686M08106 (from clone DKFZp686M08106).[CR933606] NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14),transcript variant 2, mRNA [NM_003973] NM_032378 EEF1D Homo sapienseukaryotic translation elongation factor 1 delta (guanine nucleotideexchange protein) (EEF1D), transcript variant 1, mRNA [NM_032378]XM_379885 hCG_2023776 PREDICTED: Homo sapiens similar to Heterogeneousnuclear ribonucleoprotein A1 (Helix-destabilizing protein)(Single-strand binding protein) (hnRNP core protein A1) (HDP-1)(Topoisomerase- inhibitor suppressed) (LOC402562), mRNA [XM_379885]NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863),transcript variant 1, mRNA [NM_203477] XR_018975 LOC389644 PREDICTED:Homo sapiens similar to ribosomal protein L5 (LOC389644), mRNA[XR_018975] NM_194302 CCDC108 Homo sapiens coiled-coil domain containing108 (CCDC108), transcript variant 1, mRNA [NM_194302] NM_173680 ZNF775Homo sapiens zinc finger protein 775 (ZNF775), mRNA [NM_173680]NM_016085 C2orf28 Homo sapiens chromosome 2 open reading frame 28(C2orf28), transcript variant 1, mRNA [NM_016085] NR_000029 RPL23AP7Homo sapiens ribosomal protein L23a pseudogene 7 (RPL23AP7) onchromosome 2 [NR_000029] NM_007104 RPL10A Homo sapiens ribosomal proteinL10a (RPL10A), mRNA [NM_007104] NM_003752 EIF3S8 Homo sapiens eukaryotictranslation initiation factor 3, subunit 8, 110 kDa (EIF3S8), transcriptvariant 1, mRNA [NM_003752] A_24_P358578 A_24_P358578 Unknown NM_000989RPL30 Homo sapiens ribosomal protein L30 (RPL30), mRNA [NM_000989]NM_024600 C16orf30 Homo sapiens chromosome 16 open reading frame 30(C16orf30), mRNA [NM_024600] BC030568 LOC376693 Homo sapienshypothetical LOC376693, mRNA (cDNA clone MGC: 45392 IMAGE: 5526694),complete cds. [BC030568] XM_087499 LOC152663 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L7a (LOC152663), mRNA [XM_087499]A_24_P650893 A_24_P650893 Unknown XR_019277 LOC391719 PREDICTED: Homosapiens similar to ribosomal protein L19 (LOC391719), mRNA [XR_019277]NM_001005472 LOC388524 Homo sapiens similar to Laminin receptor 1(LOC388524), mRNA [NM_001005472] BC006438 BC006438 Homo sapiens cDNAclone MGC: 13162 IMAGE: 3010103, complete cds. [BC006438] NM_001030RPS27 Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27),mRNA [NM_001030] NM_015444 TMEM158 Homo sapiens transmembrane protein158 (TMEM158), mRNA [NM_015444] NM_021103 TMSB10 Homo sapiens thymosin,beta 10 (TMSB10), mRNA [NM_021103] XR_018222 RPL31P4 PREDICTED: Homosapiens ribosomal protein L31 pseudogene 4 (RPL31P4), mRNA [XR_018222]NM_006098 GNB2L1 Homo sapiens guanine nucleotide binding protein (Gprotein), beta polypeptide 2-like 1 (GNB2L1), mRNA [NM_006098]A_32_P167577 A_32_P167577 Unknown NM_003973 RPL14 Homo sapiens ribosomalprotein L14 (RPL14), transcript variant 2, mRNA [NM_003973] NM_000967RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcript variant 1,mRNA [NM_000967] NM_033251 RPL13 Homo sapiens ribosomal protein L13(RPL13), transcript variant 2, mRNA [NM_033251] XM_001131279 LOC343851PREDICTED: Homo sapiens similar to 40S ribosomal protein S10(LOC343851), mRNA [XM_001131279] A_32_P233211 A_32_P233211 UnknownNM_001018 RPS15 Homo sapiens ribosomal protein S15 (RPS15), mRNA[NM_001018] A_24_P307255 A_24_P307255 Unknown NM_000661 RPL9 Homosapiens ribosomal protein L9 (RPL9), transcript variant 1, mRNA[NM_000661] NM_206833 CTXN1 Homo sapiens cortexin 1 (CTXN1), mRNA[NM_206833] A_24_P84408 A_24_P84408 Unknown ENST00000303979ENST00000303979 Unknown NM_014765 TOMM20 Homo sapiens translocase ofouter mitochondrial membrane 20 homolog (yeast) (TOMM20), mRNA[NM_014765] A_24_P93452 A_24_P93452 Unknown NM_005594 NACA Homo sapiensnascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA[NM_005594] XR_016879 LOC388401 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7 (LOC388401), mRNA [XR_016879] NM_001404 EEF1G Homosapiens eukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] NM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25),mRNA [NM_001028] NM_021631 FKSG2 Homo sapiens apoptosis inhibitor(FKSG2), mRNA [NM_021631] NM_203477 MGC70863 Homo sapiens similar toRPL23AP7 protein (MGC70863), transcript variant 1, mRNA [NM_203477]A_24_P881608 A_24_P881608 Unknown XR_018970 LOC391140 PREDICTED: Homosapiens similar to ribosomal protein L13 (LOC391140), mRNA [XR_018970]A_32_P95502 A_32_P95502 Unknown NM_001040437 C6orf48 Homo sapienschromosome 6 open reading frame 48 (C6orf48), transcript variant 1, mRNA[NM_001040437] XM_001128309 LOC730663 PREDICTED: Homo sapiens similar to60S ribosomal protein L23a (LOC730663), mRNA [XM_001128309] NM_000986RPL24 Homo sapiens ribosomal protein L24 (RPL24), mRNA [NM_000986]NM_001214 C16orf3 Homo sapiens chromosome 16 open reading frame 3(C16orf3), mRNA [NM_001214] A_24_P366457 A_24_P366457 Unknown AK092748RP3-377H14.5 Homo sapiens cDNA FLJ35429 fis, clone SMINT2002126.[AK092748] AK090412 LOC375010 Homo sapiens mRNA for FLJ00310 protein.[AK090412] A_24_P118874 A_24_P118874 Unknown NM_001778 CD48 Homo sapiensCD48 molecule (CD48), mRNA [NM_001778] NM_000967 RPL3 Homo sapiensribosomal protein L3 (RPL3), transcript variant 1, mRNA [NM_000967]NM_000610 CD44 Homo sapiens CD44 molecule (Indian blood group) (CD44),transcript variant 1, mRNA [NM_000610] NM_144601 CMTM3 Homo sapiensCKLF-like MARVEL transmembrane domain containing 3 (CMTM3), transcriptvariant 1, mRNA [NM_144601] NM_198969 AES Homo sapiens amino-terminalenhancer of split (AES), transcript variant 1, mRNA [NM_198969]NM_021978 ST14 Homo sapiens suppression of tumorigenicity 14 (coloncarcinoma) (ST14), mRNA [NM_021978] NM_001082575 HRNBP3 Homo sapienshypothetical protein LOC146713 (HRNBP3), mRNA [NM_001082575] NM_032378EEF1D Homo sapiens eukaryotic translation elongation factor 1 delta(guanine nucleotide exchange protein) (EEF1D), transcript variant 1,mRNA [NM_032378] XR_016930 LOC645412 PREDICTED: Homo sapiens similar to40S ribosomal protein S16 (LOC645412), mRNA [XR_016930] BC107865LOC204010 Homo sapiens similar to 40S ribosomal protein SA (P40) (34/67kDa laminin receptor) (Colon carcinoma laminin-binding protein)(NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag), mRNA(cDNA clone MGC: 104447 IMAGE: 4095371), complete cds . . . BC040156LOC284570 Homo sapiens, clone IMAGE: 4941949, mRNA. [BC040156] XR_015767LOC731224 PREDICTED: Homo sapiens similar to 60S ribosomal protein L9(LOC731224), mRNA [XR_015767] ENST00000240349 NACA3P PREDICTED: Homosapiens similar to nascent polypeptide- associated complex alphapolypeptide (LOC389240), mRNA [XM_371715] NM_007286 SYNPO Homo sapienssynaptopodin (SYNPO), mRNA [NM_007286] NM_203477 MGC70863 Homo sapienssimilar to RPL23AP7 protein (MGC70863), transcript variant 1, mRNA[NM_203477] BC047708 BC047708 Homo sapiens, clone IMAGE: 5750141, mRNA.[BC047708] NM_003202 TCF7 Homo sapiens transcription factor 7 (T-cellspecific, HMG-box) (TCF7), transcript variant 1, mRNA [NM_003202]A_23_P210285 A_23_P210285 Unknown BC028232 BC028232 Homo sapiens, cloneIMAGE: 5221276, mRNA, partial cds. [BC028232] A_24_P93052 A_24_P93052Unknown XR_018303 LOC648378 PREDICTED: Homo sapiens similar to ribosomalprotein S14 (LOC648378), mRNA [XR_018303] NM_001005472 LOC388524 Homosapiens similar to Laminin receptor 1 (LOC388524), mRNA [NM_001005472]NM_001023 RPS20 Homo sapiens ribosomal protein S20 (RPS20), mRNA[NM_001023] NM_012320 LYPLA3 Homo sapiens lysophospholipase 3 (lysosomalphospholipase A2) (LYPLA3), mRNA [NM_012320] NM_001039567 RPS4Y2 Homosapiens ribosomal protein S4, Y-linked 2 (RPS4Y2), mRNA [NM_001039567]AK124741 AK124741 Homo sapiens cDNA FLJ42751 fis, clone BRAWH3000491,moderately similar to 40S ribosomal protein S12. [AK124741] NM_020212LOC56964 Homo sapiens hypothetical protein from EUROIMAGE 384293(LOC56964), mRNA [NM_020212] AK095213 AK095213 Homo sapiens cDNAFLJ37894 fis, clone BRTHA2004639. [AK095213] THC2679528 THC2679528Unknown ENST00000335083 LOC728449 annexin A8 [Source: RefSeq_peptide;Acc: NP_001621] [ENST00000335083] NM_019059 TOMM7 Homo sapienstranslocase of outer mitochondrial membrane 7 homolog (yeast) (TOMM7),mRNA [NM_019059] NM_025228 TRAF3IP3 Homo sapiens TRAF3 interactingprotein 3 (TRAF3IP3), mRNA [NM_025228] XR_018231 LOC648027 PREDICTED:Homo sapiens similar to Elongation factor 1-gamma (EF-1-gamma) (eEF-1Bgamma) (LOC648027), mRNA [XR_018231] AK096498 AK096498 Homo sapiens cDNAFLJ39179 fis, clone OCBBF2004147. [AK096498] NM_001907 CTRL Homo sapienschymotrypsin-like (CTRL), mRNA [NM_001907] ENST00000321214 C16orf81Uncharacterized protein C16orf81. [Source: Uniprot/SPTREMBL; Acc:Q8N9R0] [ENST00000321214] NM_174918 C19orf59 Homo sapiens chromosome 19open reading frame 59 (C19orf59), mRNA [NM_174918] XR_016196 LOC642652PREDICTED: Homo sapiens hypothetical LOC642652 (LOC642652), mRNA[XR_016196] XM_372331 NKX1-2 PREDICTED: Homo sapiens NK1 transcriptionfactor related, locus 2 (Drosophila) (NKX1-2), mRNA [XM_372331]A_24_P135242 A_24_P135242 Unknown NM_033625 RPL34 Homo sapiens ribosomalprotein L34 (RPL34), transcript variant 2, mRNA [NM_033625]ENST00000321566 ENST00000321566 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7a, transcript variant 3 (LOC388474), mRNA[XM_938181] XM_060535 hCG_1641703 PREDICTED: Homo sapiens similar toribosomal protein L18a (LOC127545), mRNA [XM_060535] XR_019248 LOC130728PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC130728),mRNA [XR_019248] NM_032087 PCDHGA7 Homo sapiens protocadherin gammasubfamily A, 7 (PCDHGA7), transcript variant 2, mRNA [NM_032087]NM_004420 DUSP8 Homo sapiens dual specificity phosphatase 8 (DUSP8),mRNA [NM_004420] ENST00000237840 hCG_1642354 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L23a (LOC341511), mRNA [XM_292109]A_24_P340886 A_24_P340886 Unknown A_24_P464798 A_24_P464798 UnknownAA418814 AA418814 AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNAclone IMAGE: 767978 3′, mRNA sequence [AA418814] XM_928025 LOC644937PREDICTED: Homo sapiens similar to 60S ribosomal protein L10 (QMprotein) (Tumor suppressor QM) (Laminin receptor homolog) (LOC644937),mRNA [XM_928025] NM_006032 CPNE6 Homo sapiens copine VI (neuronal)(CPNE6), mRNA [NM_006032] XR_015402 LOC731170 PREDICTED: Homo sapienssimilar to eukaryotic translation elongation factor 1 alpha 2(LOC731170), mRNA [XR_015402] NM_002512 NME2 Homo sapiens non-metastaticcells 2, protein (NM23B) expressed in (NME2), transcript variant 1, mRNA[NM_002512] AK074447 FLJ23867 Homo sapiens cDNA FLJ23867 fis, cloneLNG09729. [AK074447] NM_138693 KLF14 Homo sapiens Kruppel-like factor 14(KLF14), mRNA [NM_138693] BG209258 LOC728315 RST28773 Athersys RAGELibrary Homo sapiens cDNA, mRNA sequence [BG209258] AK025430 AK025430Homo sapiens cDNA: FLJ21777 fis, clone HEP00173. [AK025430]ENST00000273794 LOC90113 Homo sapiens mRNA; cDNA DKFZp761K032 (fromclone DKFZp761K032). [AL834499] THC2541331 THC2541331 HSU02032 ribosomalprotein L23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (71%)[THC2541331] A_24_P32207 A_24_P32207 Unknown BX115782 BX115782 BX115782Soares_testis_NHT Homo sapiens cDNA clone IMAGp998E224413, mRNA sequence[BX115782] NM_001014 RPS10 Homo sapiens ribosomal protein S10 (RPS10),mRNA [NM_001014] THC2704973 THC2704973 Unknown NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] NM_006302 GCS1Homo sapiens glucosidase I (GCS1), mRNA [NM_006302] NM_006597 HSPA8 Homosapiens heat shock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA[NM_006597] XR_019376 LOC285260 PREDICTED: Homo sapiens similar toribosomal protein L31 (LOC285260), mRNA [XR_019376] NM_006235 POU2AF1Homo sapiens POU domain, class 2, associating factor 1 (POU2AF1), mRNA[NM_006235] AK095945 AK095945 Homo sapiens cDNA FLJ38626 fis, cloneHEART2009599. [AK095945] A_24_P221375 A_24_P221375 Unknown A_24_P341386A_24_P341386 Unknown NM_194278 C14orf43 Homo sapiens chromosome 14 openreading frame 43 (C14orf43), transcript variant 1, mRNA [NM_194278]NM_033625 RPL34 Homo sapiens ribosomal protein L34 (RPL34), transcriptvariant 2, mRNA [NM_033625] NM_003202 TCF7 Homo sapiens transcriptionfactor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] A_24_P878388 A_24_P878388 Unknown NM_033260 FOXQ1 Homosapiens forkhead box Q1 (FOXQ1), mRNA [NM_033260] XR_018786 LOC649303PREDICTED: Homo sapiens similar to ribosomal protein S10 (LOC649303),mRNA [XR_018786] NM_005356 LCK Homo sapiens lymphocyte-specific proteintyrosine kinase (LCK), transcript variant 2, mRNA [NM_005356] NM_024099C11orf48 Homo sapiens chromosome 11 open reading frame 48 (C11orf48),mRNA [NM_024099] THC2540532 THC2540532 Unknown ENST00000372073 TMEM164Transmembrane protein 164. [Source: Uniprot/SWISSPROT; Acc: Q5U3C3][ENST00000372073] BC006438 BC006438 Homo sapiens cDNA clone MGC: 13162IMAGE: 3010103, complete cds. [BC006438] A_24_P32836 A_24_P32836 UnknownENST00000359659 ENST00000359659 Q8BT90_MOUSE (Q8BT90) 10, 11 days embryowhole body cDNA, RIKEN full-length enriched library, clone: 2810021H19product: ribosomal protein S17, full insert sequence. (Fragment),partial (98%) [THC2555910] AK057177 L3MBTL2 Homo sapiens cDNA FLJ32615fis, clone STOMA2000148. [AK057177] AK025353 AK025353 Homo sapiens cDNA:FLJ21700 fis, clone COL09849, highly similar to HSU14972 Human ribosomalprotein S10 mRNA. [AK025353] ENST00000359449 ENST00000359449 Sequence237 from Patent WO0220754. [AX721277] XM_926013 LOC642398 PREDICTED:Homo sapiens hypothetical LOC642398, transcript variant 1 (LOC642398),mRNA [XM_926013] NM_052952 DIRC1 Homo sapiens disrupted in renalcarcinoma 1 (DIRC1), mRNA [NM_052952] NM_003202 TCF7 Homo sapienstranscription factor 7 (T-cell specific, HMG-box) (TCF7), transcriptvariant 1, mRNA [NM_003202] NM_052940 LRRC42 Homo sapiens leucine richrepeat containing 42 (LRRC42), mRNA [NM_052940] NM_015417 C20orf28 Homosapiens chromosome 20 open reading frame 28 (C20orf28), mRNA [NM_015417]A_24_P341176 A_24_P341176 Unknown XR_019059 LOC654170 PREDICTED: Homosapiens similar to 40S ribosomal protein S16 (LOC654170), mRNA[XR_019059] NM_014343 CLDN15 Homo sapiens claudin 15 (CLDN15),transcript variant 1, mRNA [NM_014343] A_23_P58072 A_23_P58072 UnknownTHC2611974 THC2611974 AY250221 nogo receptor-like 3 {Homo sapiens} (exp= −1; wgp = 0; cg = 0), partial (12%) [THC2611974] NM_153236 GIMAP7 Homosapiens GTPase, IMAP family member 7 (GIMAP7), mRNA [NM_153236]NM_032810 ATAD1 Homo sapiens ATPase family, AAA domain containing 1(ATAD1), mRNA [NM_032810] NM_000164 GIPR Homo sapiens gastric inhibitorypolypeptide receptor (GIPR), mRNA [NM_000164] BC011940 BC011940 Homosapiens cDNA clone IMAGE: 4329532, partial cds. [BC011940] NM_001798CDK2 Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant1, mRNA [NM_001798] A_24_P551530 A_24_P551530 Unknown NM_021130 PPIAHomo sapiens peptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA[NM_021130] XR_018155 LOC643013 PREDICTED: Homo sapiens similar tolaminin receptor 1 (ribosomal protein SA) (LOC643013), mRNA [XR_018155]NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2),transcript variant 1, mRNA [NM_020240] NM_005828 WDR68 Homo sapiens WDrepeat domain 68 (WDR68), mRNA [NM_005828] NM_004137 KCNMB1 Homo sapienspotassium large conductance calcium-activated channel, subfamily M, betamember 1 (KCNMB1), mRNA [NM_004137] NM_005309 GPT Homo sapiensglutamic-pyruvate transaminase (alanine aminotransferase) (GPT), mRNA[NM_005309] NM_198904 GABRG2 Homo sapiens gamma-aminobutyric acid (GABA)A receptor, gamma 2 (GABRG2), transcript variant 1, mRNA [NM_198904]NM_013373 ZDHHC8 Homo sapiens zinc finger, DHHC-type containing 8(ZDHHC8), mRNA [NM_013373] NM_001077710 FAM110C Homo sapiens family withsequence similarity 110, member C (FAM110C), mRNA [NM_001077710]BC018140 RPS21 Homo sapiens ribosomal protein S21, mRNA (cDNA clone MGC:9438 IMAGE: 3903320), complete cds. [BC018140] AA627135 AA627135nq71a04.s1 NCI_CGAP_Pr22 Homo sapiens cDNA clone IMAGE: 1157742 3′similar to SW: R13A_HUMAN P40429 60S RIBOSOMAL PROTEIN L13A;, mRNAsequence [AA627135] NM_000661 RPL9 Homo sapiens ribosomal protein L9(RPL9), transcript variant 1, mRNA [NM_000661] XR_018720 LOC392206PREDICTED: Homo sapiens similar to ribosomal protein L10a (LOC392206),mRNA [XR_018720] A_24_P127442 A_24_P127442 Unknown NM_016155 MMP17 Homosapiens matrix metallopeptidase 17 (membrane-inserted) (MMP17), mRNA[NM_016155] A_24_P384411 A_24_P384411 Unknown THC2506377 THC2506377HSU02032 ribosomal protein L23a {Homo sapiens} (exp = −1; wgp = 0; cg =0), partial (92%) [THC2506377] NM_001080544 LOC653314 Homo sapienssimilar to ribosomal protein L19 (LOC653314), mRNA [NM_001080544]NM_024324 CRELD2 Homo sapiens cysteine-rich with EGF-like domains 2(CRELD2), mRNA [NM_024324] BC067080 FCRLB Homo sapiens Fc receptor-likeB, mRNA (cDNA clone MGC: 71141 IMAGE: 3529386), complete cds. [BC067080]NM_004689 MTA1 Homo sapiens metastasis associated 1 (MTA1), mRNA[NM_004689] NM_002333 LRP3 Homo sapiens low density lipoproteinreceptor-related protein 3 (LRP3), mRNA [NM_002333] THC2618720THC2618720 Unknown NM_021104 RPL41 Homo sapiens ribosomal protein L41(RPL41), transcript variant 1, mRNA [NM_021104] AL834350 PPP2R5C Homosapiens mRNA; cDNA DKFZp761H0317 (from clone DKFZp761H0317). [AL834350]BCO28083 TRBV5-4 Homo sapiens T cell receptor beta variable 5-4, mRNA(cDNA clone MGC: 40031 IMAGE: 5217067), complete cds. [BC028083]ENST00000332696 ENST00000332696 similar to 60S ribosomal protein L23a(LOC644384), mRNA [Source: RefSeq_dna; Acc: XR_017413] [ENST00000332696]XR_015944 LOC731681 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L9 (LOC731681), mRNA [XR_015944] XR_019544 LOC652890 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC652890), mRNA[XR_019544] ENST00000361800 ENST00000361800 Unknown N47494 N47494 N47494yy90a12.s1 Soares_multiple_sclerosis_2NbHMSP Homo sapiens cDNA cloneIMAGE: 280798 3′ similar to gb: M23115 CALCIUM-TRANSPORTING ATPASESARCOPLASMIC RETICULUM TYPE, SLOW (HUMAN);, mRNA sequence [N47494]XR_018553 LOC648294 PREDICTED: Homo sapiens hypothetical LOC648294(LOC648294), mRNA [XR_018553] AK096778 AK096778 Homo sapiens cDNAFLJ39459 fis, clone PROST2011439. [AK096778] CN304251 CN30425117000532640995 GRN_ES Homo sapiens cDNA 5′, mRNA sequence [CN304251]NM_000545 TCF1 Homo sapiens transcription factor 1, hepatic; LF-B1,hepatic nuclear factor (HNF1), albumin proximal factor (TCF1), mRNA[NM_000545] XM_929928 LOC646960 PREDICTED: Homo sapiens similar totransmembrane protease, serine 9 (LOC646960), mRNA [XM_929928] NM_002258KLRB1 Homo sapiens killer cell lectin-like receptor subfamily B, member1 (KLRB1), mRNA [NM_002258] NM_031478 FAM57B Homo sapiens family withsequence similarity 57, member B (FAM57B), mRNA [NM_031478] A_24_P238427A_24_P238427 Unknown NM_000971 RPL7 Homo sapiens ribosomal protein L7(RPL7), mRNA [NM_000971] NR_002797 LOC255783 Homo sapiens hypotheticalprotein LOC255783 (LOC255783) on chromosome 19 [NR_002797] NM_015284KIAA0467 Homo sapiens KIAA0467 (KIAA0467), mRNA [NM_015284] NM_033060KRTAP4-10 Homo sapiens keratin associated protein 4-10 (KRTAP4-10), mRNA[NM_033060] AA451906 AA451906 AA451906 zx16h04.s1Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA clone IMAGE: 786679 3′,mRNA sequence [AA451906] AK093171 AK093171 Homo sapiens cDNA FLJ35852fis, clone TESTI2007074. [AK093171] THC2658813 THC2658813 UnknownBF822111 BF822111 BF822111 CM3-RT0011-051200-531-f10 RT0011 Homo sapienscDNA, mRNA sequence [BF822111] NM_022139 GFRA4 Homo sapiens GDNF familyreceptor alpha 4 (GFRA4), transcript variant 1, mRNA [NM_022139]AL133632 AL133632 PREDICTED: Homo sapiens hypothetical LOC648245(LOC648245), mRNA [XM_001127731] NM_152219 GJC1 Homo sapiens gapjunction protein, chi 1, 31.9 kDa (GJC1), mRNA [NM_152219] A_24_P264549A_24_P264549 Unknown NM_006013 RPL10 Homo sapiens ribosomal protein L10(RPL10), mRNA [NM_006013] A_24_P789842 A_24_P789842 Unknown NM_005356LCK Homo sapiens lymphocyte-specific protein tyrosine kinase (LCK),transcript variant 2, mRNA [NM_005356] XR_019361 LOC442260 PREDICTED:Homo sapiens similar to 60S ribosomal protein L23a (LOC442260), mRNA[XR_019361] NM_000972 RPL7A Homo sapiens ribosomal protein L7a (RPL7A),mRNA [NM_000972] ENST00000308989 ENST00000308989 PREDICTED: Homo sapienssimilar to ribosomal protein L31 (LOC729005), mRNA [XM_001133428]NM_003202 TCF7 Homo sapiens transcription factor 7 (T-cell specific,HMG-box) (TCF7), transcript variant 1, mRNA [NM_003202] NM_003775 EDG6Homo sapiens endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6 (EDG6), mRNA [NM_003775] ENST00000323800ENST00000323800 CDNA FLJ25155 fis, clone CBR07976. [Source:Uniprot/SPTREMBL; Acc: Q96LR6] [ENST00000323800] NM_002300 LDHB Homosapiens lactate dehydrogenase B (LDHB), mRNA [NM_002300] NM_000984RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984]NM_130759 GIMAP1 Homo sapiens GTPase, IMAP family member 1 (GIMAP1),mRNA [NM_130759] ENST00000307437 ENST00000307437 PREDICTED: Homo sapienssimilar to ribosomal protein S12 (LOC727997), mRNA [XM_001127053]BC002431 B4GALT2 Homo sapiens cDNA clone IMAGE: 3347310, containingframe-shift errors. [BC002431] NM_033405 PRIC285 Homo sapiensperoxisomal proliferator-activated receptor A interacting complex 285(PRIC285), transcript variant 2, mRNA [NM_033405] NM_000983 RPL22 Homosapiens ribosomal protein L22 (RPL22), mRNA [NM_000983] NM_152636METT5D1 Homo sapiens methyltransferase 5 domain containing 1 (METT5D1),mRNA [NM_152636] NM_015481 ZNF385 Homo sapiens zinc finger protein 385(ZNF385), mRNA [NM_015481] AY090769 AY090769 Homo sapiens ribosomalprotein S18/S6-like mRNA, complete sequence. [AY090769] NM_001402 EEF1A1Homo sapiens eukaryotic translation elongation factor 1 alpha 1(EEF1A1), mRNA [NM_001402] NM_182796 MAT2B Homo sapiens methionineadenosyltransferase II, beta (MAT2B), transcript variant 2, mRNA[NM_182796] XM_927514 LOC644357 PREDICTED: Homo sapiens similar toElongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) (LOC644357),mRNA [XM_927514] NM_002818 PSME2 Homo sapiens proteasome (prosome,macropain) activator subunit 2 (PA28 beta) (PSME2), mRNA [NM_002818]NM_176812 CHMP4B Homo sapiens chromatin modifying protein 4B (CHMP4B),mRNA [NM_176812] A_24_P298238 A_24_P298238 Unknown NM_003202 TCF7 Homosapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7),transcript variant 1, mRNA [NM_003202] A_24_P212654 A_24_P212654 UnknownA_24_P392436 A_24_P392436 Unknown A_24_P350008 A_24_P350008 UnknownENST00000367058 CR2 Complement receptor type 2 precursor (Cr2)(Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor)(CD21 antigen). [Source: Uniprot/SWISSPROT; Acc: P20023][ENST00000367058] A_24_P33213 A_24_P33213 Unknown NM_001014373 C19orf31Homo sapiens chromosome 19 open reading frame 31 (C19orf31), mRNA[NM_001014373] NM_001039842 LOC339229 Homo sapiens hypothetical proteinLOC339229 (LOC339229), mRNA [NM_001039842] NM_012423 RPL13A Homo sapiensribosomal protein L13a (RPL13A), mRNA [NM_012423] NM_025247 ACAD10 Homosapiens acyl-Coenzyme A dehydrogenase family, member 10 (ACAD10), mRNA[NM_025247] THC2494410 THC2494410 2113200F ribosomal protein S9. {Homosapiens} (exp = −1; wgp = −1; cg = −1), complete [THC2494410] NM_005581BCAM Homo sapiens basal cell adhesion molecule (Lutheran blood group)(BCAM), transcript variant 1, mRNA [NM_005581] XR_018133 LOC389404PREDICTED: Homo sapiens similar to 60S ribosomal protein L9 (LOC389404),mRNA [XR_018133] AK025669 AK025669 Homo sapiens cDNA: FLJ22016 fis,clone HEP07422. [AK025669] NM_201286 USP51 Homo sapiens ubiquitinspecific peptidase 51 (USP51), mRNA [NM_201286] NM_003202 TCF7 Homosapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7),transcript variant 1, mRNA [NM_003202] XR_019386 LOC652558 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC652558), mRNA[XR_019386] A_24_P213073 A_24_P213073 Unknown NM_021173 POLD4 Homosapiens polymerase (DNA-directed), delta 4 (POLD4), mRNA [NM_021173]A_24_P392195 A_24_P392195 Unknown THC2782843 THC2782843 RL18A_HUMAN(Q02543) 60S ribosomal protein L18a, partial (89%) [THC2782843]NM_152889 CHST13 Homo sapiens carbohydrate (chondroitin 4)sulfotransferase 13 (CHST13), mRNA [NM_152889] NM_001017 RPS13 Homosapiens ribosomal protein S13 (RPS13), mRNA [NM_001017] THC2737361THC2737361 Q2IMJ3_ANADE (Q2IMJ3) LigA, partial (5%) [THC2737361]XR_018509 LOC391701 PREDICTED: Homo sapiens similar to ribosomal proteinS23 (LOC391701), mRNA [XR_018509] THC2615996 THC2615996 UnknownNM_080660 ZC3HAV1L Homo sapiens zinc finger CCCH-type, antiviral 1-like(ZC3HAV1L), mRNA [NM_080660] NM_203305 FAM102A Homo sapiens family withsequence similarity 102, member A (FAM102A), transcript variant 2, mRNA[NM_203305] XM_930195 hCG_18290 PREDICTED: Homo sapiens similar to 60Sribosomal protein L32 (LOC644907), mRNA [XM_930195] NM_013284 POLM Homosapiens polymerase (DNA directed), mu (POLM), mRNA [NM_013284] NM_138425C12orf57 Homo sapiens chromosome 12 open reading frame 57 (C12orf57),mRNA [NM_138425] AK098605 AK098605 Homo sapiens cDNA FLJ25739 fis, cloneTST05834. [AK098605] THC2544911 THC2544911 MUSEFTU elongation factor Tu{Mus musculus} (exp = −1; wgp = 0; cg = 0), partial (37%) [THC2544911]BC063671 LOC92659 Homo sapiens hypothetical protein BC009233, mRNA (cDNAclone IMAGE: 3924188), partial cds. [BC063671] NM_001404 EEF1G Homosapiens eukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] NM_014931 SAPS1 Homo sapiens SAPS domain family, member 1(SAPS1), mRNA [NM_014931] XM_001125895 LOC730452 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L7 (LOC730452), mRNA [XM_001125895]AK021957 COL27A1 Homo sapiens cDNA FLJ11895 fis, clone HEMBA1007301,weakly similar to COLLAGEN ALPHA 1(III) CHAIN. [AK021957] NM_006291TNFAIP2 Homo sapiens tumor necrosis factor, alpha-induced protein 2(TNFAIP2), mRNA [NM_006291] NM_006597 HSPA8 Homo sapiens heat shock 70kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597] THC2694215THC2694215 Q3W9Q7_9ACTO (Q3W9Q7) Pyridoxamine 5′-phosphate oxidase,partial (3%) [THC2694215] NM_021959 PPP1R11 Homo sapiens proteinphosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA[NM_021959] A_32_P208856 A_32_P208856 Unknown NM_177458 LYNX1 Homosapiens Ly6/neurotoxin 1 (LYNX1), transcript variant SLURP2, mRNA[NM_177458] THC2650296 THC2650296 RL18A_MOUSE (P62717) 60S ribosomalprotein L18a, complete [THC2650296] NM_138732 NRXN2 Homo sapiensneurexin 2 (NRXN2), transcript variant alpha-2, mRNA [NM_138732]NM_080746 RPL10L Homo sapiens ribosomal protein L10-like (RPL10L), mRNA[NM_080746] NM_001005291 SREBF1 Homo sapiens sterol regulatory elementbinding transcription factor 1 (SREBF1), transcript variant 1, mRNA[NM_001005291] A_24_P194954 A_24_P194954 Unknown NM_145245 EVI5L Homosapiens ecotropic viral integration site 5-like (EVI5L), mRNA[NM_145245] NM_016337 EVL Homo sapiens Enah/Vasp-like (EVL), mRNA[NM_016337] NM_032152 PRAM1 Homo sapiens PML-RARA regulated adaptormolecule 1 (PRAM1), mRNA [NM_032152] NM_003202 TCF7 Homo sapienstranscription factor 7 (T-cell specific, HMG-box) (TCF7), transcriptvariant 1, mRNA [NM_003202] THC2560098 THC2560098 S35960 C-terminal{Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (64%) [THC2560098]A_24_P273074 A_24_P273074 Unknown AX721252 AX721252 Sequence 212 fromPatent WO0220754. [AX721252] NM_000972 RPL7A Homo sapiens ribosomalprotein L7a (RPL7A), mRNA [NM_000972] NM_006013 RPL10 Homo sapiensribosomal protein L10 (RPL10), mRNA [NM_006013] NM_003202 TCF7 Homosapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7),transcript variant 1, mRNA [NM_003202] A_24_P101271 A_24_P101271 UnknownXR_019375 LOC645326 PREDICTED: Homo sapiens similar to laminin receptor1 (ribosomal protein SA) (LOC645326), mRNA [XR_019375] A_24_P332292A_24_P332292 Unknown NM_001402 EEF1A1 Homo sapiens eukaryotictranslation elongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402]NM_000981 RPL19 Homo sapiens ribosomal protein L19 (RPL19), mRNA[NM_000981] NM_152525 ALS2CR11 Homo sapiens amyotrophic lateralsclerosis 2 (juvenile) chromosome region, candidate 11 (ALS2CR11), mRNA[NM_152525] NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9),transcript variant 1, mRNA [NM_000661] NM_033625 RPL34 Homo sapiensribosomal protein L34 (RPL34), transcript variant 2, mRNA [NM_033625]NM_175065 HIST2H2AB Homo sapiens histone cluster 2, H2ab (HIST2H2AB),mRNA [NM_175065] NM_015355 SUZ12 Homo sapiens suppressor of zeste 12homolog (Drosophila) (SUZ12), mRNA [NM_015355] A_24_P170103 A_24_P170103Unknown A_32_P25838 A_32_P25838 Unknown ENST00000332289 ENST00000332289PREDICTED: Homo sapiens similar to 40S ribosomal protein SA (p40) (34[XR_019580] CR627135 CR627135 Homo sapiens mRNA; cDNA DKFZp779J0122(from clone DKFZp779J0122). [CR627135] A_32_P101195 A_32_P101195 UnknownNM_000969 RPL5 Homo sapiens ribosomal protein L5 (RPL5), mRNA[NM_000969] NM_033184 KRTAP2-4 Homo sapiens keratin associated protein2-4 (KRTAP2-4), mRNA [NM_033184] NM_024012 HTR5A Homo sapiens5-hydroxytryptamine (serotonin) receptor 5A (HTR5A), mRNA [NM_024012]A_24_P410070 A_24_P410070 Unknown XM_374010 LOC389033 PREDICTED: Homosapiens hypothetical LOC389033 (LOC389033), mRNA [XM_374010] NM_033251RPL13 Homo sapiens ribosomal protein L13 (RPL13), transcript variant 2,mRNA [NM_033251] XR_015548 LOC729449 PREDICTED: Homo sapiens similar to60S ribosomal protein L7 (LOC729449), mRNA [XR_015548] THC2533996THC2533996 HSU09954 ribosomal protein L9 {Homo sapiens} (exp = −1; wgp =0; cg = 0), partial (42%) [THC2533996] NM_015937 PIGT Homo sapiensphosphatidylinositol glycan anchor biosynthesis, class T (PIGT), mRNA[NM_015937] NM_019059 TOMM7 Homo sapiens translocase of outermitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA [NM_019059]NM_001778 CD48 Homo sapiens CD48 molecule (CD48), mRNA [NM_001778]NR_002778 RPL29P2 Homo sapiens ribosomal protein L29 pseudogene 2(RPL29P2) on chromosome 17 [NR_002778] THC2689192 THC2689192Q7XC69_ORYSA (Q7XC69) Expressed protein, partial (6%) [THC2689192]BE843546 BE843546 BE843546 CM3-TN0066-080800-269-g03 TN0066 Homo sapienscDNA, mRNA sequence [BE843546] A_24_P714750 A_24_P714750 UnknownNM_017801 CMTM6 Homo sapiens CKLF-like MARVEL transmembrane domaincontaining 6 (CMTM6), mRNA [NM_017801] NM_016270 KLF2 Homo sapiensKruppel-like factor 2 (lung) (KLF2), mRNA [NM_016270] XR_017260LOC646710 PREDICTED: Homo sapiens hypothetical LOC646710 (LOC646710),mRNA [XR_017260] XR_018341 LOC390413 PREDICTED: Homo sapiens similar to60S ribosomal protein L7 (LOC390413), mRNA [XR_018341] NM_023078 PYCRLHomo sapiens pyrroline-5-carboxylate reductase-like (PYCRL), mRNA[NM_023078] NM_000979 RPL18 Homo sapiens ribosomal protein L18 (RPL18),mRNA [NM_000979] XR_018054 LOC392878 PREDICTED: Homo sapienshypothetical LOC392878 (LOC392878), mRNA [XR_018054] NM_001005472LOC388524 Homo sapiens similar to Laminin receptor 1 (LOC388524), mRNA[NM_001005472] NM_018326 GIMAP4 Homo sapiens GTPase, IMAP family member4 (GIMAP4), mRNA [NM_018326] NM_013234 EIF3S12 Homo sapiens eukaryotictranslation initiation factor 3, subunit 12 (EIF3S12), mRNA [NM_013234]BC024303 FLJ35390 Homo sapiens hypothetical protein FLJ35390, mRNA (cDNAclone IMAGE: 4328569), with apparent retained intron. [BC024303]NM_000982 RPL21 Homo sapiens ribosomal protein L21 (RPL21), mRNA[NM_000982] NM_032611 PTP4A3 Homo sapiens protein tyrosine phosphatasetype IVA, member 3 (PTP4A3), transcript variant 1, mRNA [NM_032611]A_24_P67308 A_24_P67308 Unknown NM_001404 EEF1G Homo sapiens eukaryotictranslation elongation factor 1 gamma (EEF1G), mRNA [NM_001404]NM_001039211 ATAD3C Homo sapiens ATPase family, AAA domain containing 3C(ATAD3C), mRNA [NM_001039211] NM_001967 EIF4A2 Homo sapiens eukaryotictranslation initiation factor 4A, isoform 2 (EIF4A2), mRNA [NM_001967]NM_001011 RPS7 Homo sapiens ribosomal protein S7 (RPS7), mRNA[NM_001011] ENST00000333351 ENST00000333351 PREDICTED: Homo sapienshypothetical LOC391504 (LOC391504), mRNA [XR_018627] A_24_P204474A_24_P204474 Unknown NM_001861 COX4I1 Homo sapiens cytochrome c oxidasesubunit IV isoform 1 (COX4I1), mRNA [NM_001861] NM_178230 PPIAL4 Homosapiens peptidylprolyl isomerase A (cyclophilin A)-like 4 (PPIAL4), mRNA[NM_178230] NM_017549 EPDR1 Homo sapiens ependymin related protein 1(zebrafish) (EPDR1), mRNA [NM_017549] AL547890 AL547890 AL547890AL547890 Homo sapiens PLACENTA COT 25- NORMALIZED Homo sapiens cDNAclone CS0DI033YB09 5- PRIME, mRNA sequence [AL547890] A_24_P392790A_24_P392790 Unknown XR_017498 LOC645693 PREDICTED: Homo sapiens similarto eukaryotic translation elongation factor 1 alpha 2 (LOC645693), mRNA[XR_017498] NM_003754 EIF3S5 Homo sapiens eukaryotic translationinitiation factor 3, subunit 5 epsilon, 47 kDa (EIF3S5), mRNA[NM_003754] NM_001008 RPS4Y1 Homo sapiens ribosomal protein S4, Y-linked1 (RPS4Y1), mRNA [NM_001008] NM_002405 MFNG Homo sapiens MFNGO-fucosylpeptide 3-beta-N- acetylglucosaminyltransferase (MFNG), mRNA[NM_002405] A_24_P324224 A_24_P324224 Unknown A_24_P714620 A_24_P714620Unknown NM_001017418 SPRR2B Homo sapiens small proline-rich protein 2B(SPRR2B), mRNA [NM_001017418] NM_015853 LOC51035 Homo sapiens SAPKsubstrate protein 1 (LOC51035), mRNA [NM_015853] NM_018949 UTS2R Homosapiens urotensin 2 receptor (UTS2R), mRNA [NM_018949] NM_001005472LOC388524 Homo sapiens similar to Laminin receptor 1 (LOC388524), mRNA[NM_001005472] A_24_P375435 A_24_P375435 Unknown NM_000967 RPL3 Homosapiens ribosomal protein L3 (RPL3), transcript variant 1, mRNA[NM_000967] NM_015646 RAP1B Homo sapiens RAP1B, member of RAS oncogenefamily (RAP1B), transcript variant 1, mRNA [NM_015646] A_24_P212726A_24_P212726 Unknown NM_006682 FGL2 Homo sapiens fibrinogen-like 2(FGL2), mRNA [NM_006682] NM_001014 RPS10 Homo sapiens ribosomal proteinS10 (RPS10), mRNA [NM_001014] XR_017294 LOC646949 PREDICTED: Homosapiens similar to ribosomal protein L23 (LOC646949), mRNA [XR_017294]NM_001212 C1QBP Homo sapiens complement component 1, q subcomponentbinding protein (C1QBP), nuclear gene encoding mitochondrial protein,mRNA [NM_001212] XR_018025 LOC641790 PREDICTED: Homo sapiens similar toribosomal protein L31 (LOC641790), mRNA [XR_018025] A_24_P289884A_24_P289884 Unknown NR_001577 NME2P1 Homo sapiens non-metastatic cells2, protein (NM23B) expressed in, pseudogene 1 (NME2P1) on chromosome 12[NR_001577] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] BC005008 CEACAM6 Homosapiens carcinoembryonic antigen-related cell adhesion molecule 6(non-specific cross reacting antigen), mRNA (cDNA clone MGC: 10467IMAGE: 3640231), complete cds. [BC005008] NM_003757 EIF3S2 Homo sapienseukaryotic translation initiation factor 3, subunit 2 beta, 36 kDa(EIF3S2), mRNA [NM_003757] NM_001402 EEF1A1 Homo sapiens eukaryotictranslation elongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402]NM_001005472 LOC388524 Homo sapiens similar to Laminin receptor 1(LOC388524), mRNA [NM_001005472] NM_021130 PPIA Homo sapienspeptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA [NM_021130]A_24_P505981 A_24_P505981 Unknown NM_005401 PTPN14 Homo sapiens proteintyrosine phosphatase, non-receptor type 14 (PTPN14), mRNA [NM_005401]NM_031918 KLF16 Homo sapiens Kruppel-like factor 16 (KLF16), mRNA[NM_031918]

TABLE 12 Gene list generated at the inclusion criteria of p ≦ 1 × 10⁻³and the log-median-ratio being below being at least “1” or above, orbeing “−1” or below. GenBank Accession GeneName Description NM_001039567RPS4Y2 Homo sapiens ribosomal protein S4, Y-linked 2 (RPS4Y2), mRNA[NM_001039567] NM_001008 RPS4Y1 Homo sapiens ribosomal protein S4,Y-linked 1 (RPS4Y1), mRNA [NM_001008] NM_002985 CCL5 Homo sapienschemokine (C-C motif) ligand 5 (CCL5), mRNA [NM_002985] NM_004907 IER2Homo sapiens immediate early response 2 (IER2), mRNA [NM_004907]NM_015646 RAP1B Homo sapiens RAP1B, member of RAS oncogene family(RAP1B), transcript variant 1, mRNA [NM_015646] NM_002490 NDUFA6 Homosapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14 kDa(NDUFA6), nuclear gene encoding mitochondrial protein, mRNA [NM_002490]AL049447 AL049447 Homo sapiens mRNA; cDNA DKFZp586A0722 (from cloneDKFZp586A0722). [AL049447] NM_012329 MMD Homo sapiens monocyte tomacrophage differentiation-associated (MMD), mRNA [NM_012329] NM_004048B2M Homo sapiens beta-2-microglobulin (B2M), mRNA [NM_004048] NM_001004RPLP2 Homo sapiens ribosomal protein, large, P2 (RPLP2), mRNA[NM_001004] NM_033251 RPL13 Homo sapiens ribosomal protein L13 (RPL13),transcript variant 2, mRNA [NM_033251] ENST00000383061 ENST00000383061PREDICTED: Homo sapiens similar to myosin regulatory light chain-like(LOC442204), mRNA [XM_498088] NM_004907 IER2 Homo sapiens immediateearly response 2 (IER2), mRNA [NM_004907] NM_001803 CD52 Homo sapiensCD52 molecule (CD52), mRNA [NM_001803] NM_145113 MAX Homo sapiens MYCassociated factor X (MAX), transcript variant 3, mRNA [NM_145113]NM_002954 RPS27A Homo sapiens ribosomal protein S27a (RPS27A), mRNA[NM_002954] A_24_P144383 A_24_P144383 Unknown NM_006471 MRCL3 Homosapiens myosin regulatory light chain MRCL3 (MRCL3), mRNA [NM_006471]NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8 (HSPA8),transcript variant 1, mRNA [NM_006597] NM_001402 EEF1A1 Homo sapienseukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA[NM_001402] NM_001030 RPS27 Homo sapiens ribosomal protein S27(metallopanstimulin 1) (RPS27), mRNA [NM_001030] NM_080425 GNAS Homosapiens GNAS complex locus (GNAS), transcript variant 2, mRNA[NM_080425] NM_001032 RPS29 Homo sapiens ribosomal protein S29 (RPS29),transcript variant 1, mRNA [NM_001032] NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] NM_007262 PARK7 Homosapiens Parkinson disease (autosomal recessive, early onset) 7 (PARK7),mRNA [NM_007262] NM_001012 RPS8 Homo sapiens ribosomal protein S8(RPS8), mRNA [NM_001012] NM_005594 NACA Homo sapiensnascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA[NM_005594] XR_017498 LOC645693 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 alpha 2 (LOC645693), mRNA[XR_017498] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_001778 CD48 Homosapiens CD48 molecule (CD48), mRNA [NM_001778] NM_001017 RPS13 Homosapiens ribosomal protein S13 (RPS13), mRNA [NM_001017] NM_001030 RPS27Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA[NM_001030] NM_000968 RPL4 Homo sapiens ribosomal protein L4 (RPL4),mRNA [NM_000968] NM_004657 SDPR Homo sapiens serum deprivation response(phosphatidylserine binding protein) (SDPR), mRNA [NM_004657] XR_018386LOC392358 PREDICTED: Homo sapiens similar to 40S ribosomal protein S6(LOC392358), mRNA [XR_018386] NM_002945 RPA1 Homo sapiens replicationprotein A1, 70 kDa (RPA1), mRNA [NM_002945] THC2544911 THC2544911MUSEFTU elongation factor Tu {Mus musculus} (exp = −1; wgp = 0; cg = 0),partial (37%) [THC2544911] NM_001017 RPS13 Homo sapiens ribosomalprotein S13 (RPS13), mRNA [NM_001017] NM_021104 RPL41 Homo sapiensribosomal protein L41 (RPL41), transcript variant 1, mRNA [NM_021104]NM_000981 RPL19 Homo sapiens ribosomal protein L19 (RPL19), mRNA[NM_000981] THC2527647 THC2527647 Q59GY2_HUMAN (Q59GY2) Ribosomalprotein L4 variant (Fragment), partial (51%) [THC2527647] A_24_P929974A_24_P929974 Unknown NM_002300 LDHB Homo sapiens lactate dehydrogenase B(LDHB), mRNA [NM_002300] NM_033251 RPL13 Homo sapiens ribosomal proteinL13 (RPL13), transcript variant 2, mRNA [NM_033251] NM_001031 RPS28 Homosapiens ribosomal protein S28 (RPS28), mRNA [NM_001031] M36647 UQCRHHomo sapiens mitochondrial hinge protein precursor, mRNA, complete cds.[M36647] NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14),transcript variant 2, mRNA [NM_003973] NM_000978 RPL23 Homo sapiensribosomal protein L23 (RPL23), mRNA [NM_000978] NM_033251 RPL13 Homosapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] NM_001003 RPLP1 Homo sapiens ribosomal protein, large, P1(RPLP1), transcript variant 1, mRNA [NM_001003] NM_001568 EIF3S6 Homosapiens eukaryotic translation initiation factor 3, subunit 6 48 kDa(EIF3S6), mRNA [NM_001568] A_24_P392195 A_24_P392195 Unknown NM_001028RPS25 Homo sapiens ribosomal protein S25 (RPS25), mRNA [NM_001028]NM_003756 EIF3S3 Homo sapiens eukaryotic translation initiation factor3, subunit 3 gamma, 40 kDa (EIF3S3), mRNA [NM_003756] NM_001032 RPS29Homo sapiens ribosomal protein S29 (RPS29), transcript variant 1, mRNA[NM_001032] A_24_P238426 A_24_P238426 Unknown BX096698 BX096698 BX096698Soares breast 2NbHBst Homo sapiens cDNA clone IMAGp998E11242, mRNAsequence [BX096698] XR_017260 LOC646710 PREDICTED: Homo sapienshypothetical LOC646710 (LOC646710), mRNA [XR_017260] A_24_P333112A_24_P333112 Unknown NM_001003 RPLP1 Homo sapiens ribosomal protein,large, P1 (RPLP1), transcript variant 1, mRNA [NM_001003] NM_002823 PTMAHomo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA[NM_002823] NM_033251 RPL13 Homo sapiens ribosomal protein L13 (RPL13),transcript variant 2, mRNA [NM_033251] XR_017294 LOC646949 PREDICTED:Homo sapiens similar to ribosomal protein L23 (LOC646949), mRNA[XR_017294] XR_016779 LOC440311 PREDICTED: Homo sapiens similar toGlioma tumor suppressor candidate region gene 2 protein (p60)(LOC440311), mRNA [XR_016779] NM_002085 GPX4 Homo sapiens glutathioneperoxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant1, mRNA [NM_002085] NM_000993 RPL31 Homo sapiens ribosomal protein L31(RPL31), mRNA [NM_000993] XR_015548 LOC729449 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L7 (LOC729449), mRNA [XR_015548]NM_199290 NACA2 Homo sapiens nascent-polypeptide-associated complexalpha polypeptide-like (NACAL), mRNA [NM_199290] BC052613 LOC728131 Homosapiens cDNA clone MGC: 59872 IMAGE: 6301163, complete cds. [BC052613]A_24_P306968 A_24_P306968 Unknown A_32_P49392 A_32_P49392 UnknownXM_497657 LOC441876 PREDICTED: Homo sapiens similar to 40S ribosomalprotein S16, transcript variant 1 (LOC441876), mRNA [XM_497657]NM_001025 RPS23 Homo sapiens ribosomal protein S23 (RPS23), mRNA[NM_001025] BU956542 BU956542 BU956542 AGENCOURT_10615527 NIH_MGC_107Homo sapiens cDNA clone IMAGE: 6730153 5′, mRNA sequence [BU956542]AK027315 AK027315 Homo sapiens cDNA FLJ14409 fis, clone HEMBA1004408,moderately similar to PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 10 (EC5.2.1.8). [AK027315] NM_006597 HSPA8 Homo sapiens heat shock 70 kDaprotein 8 (HSPA8), transcript variant 1, mRNA [NM_006597] NM_001006RPS3A Homo sapiens ribosomal protein S3A (RPS3A), mRNA [NM_001006]NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1alpha 1 (EEF1A1), mRNA [NM_001402] NM_001568 EIF3S6 Homo sapienseukaryotic translation initiation factor 3, subunit 6 48 kDa (EIF3S6),mRNA [NM_001568] NM_001436 FBL Homo sapiens fibrillarin (FBL), mRNA[NM_001436] NM_000975 RPL11 Homo sapiens ribosomal protein L11 (RPL11),mRNA [NM_000975] NM_033546 MRLC2 Homo sapiens myosin regulatory lightchain MRLC2 (MRLC2), mRNA [NM_033546] A_32_P128781 A_32_P128781 UnknownXR_018063 LOC392030 PREDICTED: Homo sapiens hypothetical LOC392030(LOC392030), mRNA [XR_018063] A_24_P298835 A_24_P298835 UnknownA_23_P200955 A_23_P200955 Unknown A_24_P341376 A_24_P341376 UnknownNM_080392 PTP4A2 Homo sapiens protein tyrosine phosphatase type IVA,member 2 (PTP4A2), transcript variant 2, mRNA [NM_080392]ENST00000312528 ENST00000312528 Unknown NM_015710 GLTSCR2 Homo sapiensglioma tumor suppressor candidate region gene 2 (GLTSCR2), mRNA[NM_015710] NM_001402 EEF1A1 Homo sapiens eukaryotic translationelongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_025228TRAF3IP3 Homo sapiens TRAF3 interacting protein 3 (TRAF3IP3), mRNA[NM_025228] NM_002624 PFDN5 Homo sapiens prefoldin subunit 5 (PFDN5),transcript variant 1, mRNA [NM_002624] A_24_P160920 A_24_P160920 UnknownA_24_P332292 A_24_P332292 Unknown NM_198969 AES Homo sapiensamino-terminal enhancer of split (AES), transcript variant 1, mRNA[NM_198969] NM_000989 RPL30 Homo sapiens ribosomal protein L30 (RPL30),mRNA [NM_000989] A_24_P878388 A_24_P878388 Unknown NM_001402 EEF1A1 Homosapiens eukaryotic translation elongation factor 1 alpha 1 (EEF1A1),mRNA [NM_001402] NM_000989 RPL30 Homo sapiens ribosomal protein L30(RPL30), mRNA [NM_000989] XR_016879 LOC388401 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L7 (LOC388401), mRNA [XR_016879]NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcriptvariant 1, mRNA [NM_000967] ENST00000337102 ENST00000337102 40Sribosomal protein S21. [Source: Uniprot/SWISSPROT; Acc: P63220][ENST00000337102] NM_006263 PSME1 Homo sapiens proteasome (prosome,macropain) activator subunit 1 (PA28 alpha) (PSME1), transcript variant1, mRNA [NM_006263] XR_018138 LOC392497 PREDICTED: Homo sapiens similarto 40S ribosomal protein S6 (LOC392497), mRNA [XR_018138] NM_002341 LTBHomo sapiens lymphotoxin beta (TNF superfamily, member 3) (LTB),transcript variant 1, mRNA [NM_002341] NM_000967 RPL3 Homo sapiensribosomal protein L3 (RPL3), transcript variant 1, mRNA [NM_000967]A_24_P84408 A_24_P84408 Unknown NM_002121 HLA-DPB1 Homo sapiens majorhistocompatibility complex, class II, DP beta 1 (HLA-DPB1), mRNA[NM_002121] NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9),transcript variant 1, mRNA [NM_000661] NM_000991 RPL28 Homo sapiensribosomal protein L28 (RPL28), mRNA [NM_000991] NM_001006 RPS3A Homosapiens ribosomal protein S3A (RPS3A), mRNA [NM_001006] NM_001006 RPS3AHomo sapiens ribosomal protein S3A (RPS3A), mRNA [NM_001006] NM_000661RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcript variant 1,mRNA [NM_000661] A_24_P650893 A_24_P650893 Unknown A_24_P50567A_24_P50567 Unknown A_24_P136011 A_24_P136011 Unknown A_24_P298238A_24_P298238 Unknown THC2541331 THC2541331 HSU02032 ribosomal proteinL23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (71%)[THC2541331] XR_018025 LOC641790 PREDICTED: Homo sapiens similar toribosomal protein L31 (LOC641790), mRNA [XR_018025] NM_003295 TPT1 Homosapiens tumor protein, translationally-controlled 1 (TPT1), mRNA[NM_003295] NM_001867 COX7C Homo sapiens cytochrome c oxidase subunitVIIc (COX7C), nuclear gene encoding mitochondrial protein, mRNA[NM_001867] BC018140 RPS21 Homo sapiens ribosomal protein S21, mRNA(cDNA clone MGC: 9438 IMAGE: 3903320), complete cds. [BC018140]NM_005340 HINT1 Homo sapiens histidine triad nucleotide binding protein1 (HINT1), mRNA [NM_005340] BC067891 LOC645683 Homo sapiens cDNA cloneMGC: 87657 IMAGE: 5271409, complete cds. [BC067891] ENST00000308989ENST00000308989 PREDICTED: Homo sapiens similar to ribosomal protein L31(LOC729005), mRNA [XM_001133428] A_24_P212726 A_24_P212726 UnknownNM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25), mRNA[NM_001028] NM_000998 RPL37A Homo sapiens ribosomal protein L37a(RPL37A), mRNA [NM_000998] XR_015402 LOC731170 PREDICTED: Homo sapienssimilar to eukaryotic translation elongation factor 1 alpha 2(LOC731170), mRNA [XR_015402] A_24_P340886 A_24_P340886 UnknownNM_016480 PAIP2 Homo sapiens poly(A) binding protein interacting protein2 (PAIP2), transcript variant 2, mRNA [NM_016480] THC2567891 THC2567891Q6NXR8_HUMAN (Q6NXR8) Ribosomal protein S3a, partial (91%) [THC2567891]XR_019376 LOC285260 PREDICTED: Homo sapiens similar to ribosomal proteinL31 (LOC285260), mRNA [XR_019376] ENST00000359449 ENST00000359449Sequence 237 from Patent WO0220754. [AX721277] NM_000988 RPL27 Homosapiens ribosomal protein L27 (RPL27), mRNA [NM_000988] XR_018975LOC389644 PREDICTED: Homo sapiens similar to ribosomal protein L5(LOC389644), mRNA [XR_018975] XR_019168 LOC391847 PREDICTED: Homosapiens similar to ribosomal protein L19 (LOC391847), mRNA [XR_019168]A_24_P505981 A_24_P505981 Unknown CD174733 CD174733 CD174733AGENCOURT_13961604 NIH_MGC_172 Homo sapiens cDNA 5′, mRNA sequence[CD174733] ENST00000240349 NACA3P PREDICTED: Homo sapiens similar tonascent polypeptide- associated complex alpha polypeptide (LOC389240),mRNA [XM_371715] A_24_P221375 A_24_P221375 Unknown NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] XR_018231LOC648027 PREDICTED: Homo sapiens similar to Elongation factor 1-gamma(EF-1-gamma) (eEF-1B gamma) (LOC648027), mRNA [XR_018231] NM_003753EIF3S7 Homo sapiens eukaryotic translation initiation factor 3, subunit7 zeta, 66/67 kDa (EIF3S7), mRNA [NM_003753] NM_000978 RPL23 Homosapiens ribosomal protein L23 (RPL23), mRNA [NM_000978] BC001697 RPS15AHomo sapiens ribosomal protein S15a, mRNA (cDNA clone MGC: 2466 IMAGE:2967511), complete cds. [BC001697] NM_013234 EIF3S12 Homo sapienseukaryotic translation initiation factor 3, subunit 12 (EIF3S12), mRNA[NM_013234] NM_001022 RPS19 Homo sapiens ribosomal protein S19 (RPS19),mRNA [NM_001022] NM_001007074 RPL32 Homo sapiens ribosomal protein L32(RPL32), transcript variant 3, mRNA [NM_001007074] NM_001861 COX4I1 Homosapiens cytochrome c oxidase subunit IV isoform 1 (COX4I1), mRNA[NM_001861] XR_019544 LOC652890 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7 (LOC652890), mRNA [XR_019544] A_24_P41979A_24_P41979 Unknown NM_003746 DYNLL1 Homo sapiens dynein, light chain,LC8-type 1 (DYNLL1), transcript variant 3, mRNA [NM_003746] NM_000982RPL21 Homo sapiens ribosomal protein L21 (RPL21), mRNA [NM_000982]A_23_P210285 A_23_P210285 Unknown NM_002539 ODC1 Homo sapiens ornithinedecarboxylase 1 (ODC1), mRNA [NM_002539] XR_019361 LOC442260 PREDICTED:Homo sapiens similar to 60S ribosomal protein L23a (LOC442260), mRNA[XR_019361] A_24_P289884 A_24_P289884 Unknown A_24_P135242 A_24_P135242Unknown NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14),transcript variant 2, mRNA [NM_003973] XR_019386 LOC652558 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC652558), mRNA[XR_019386] ENST00000381140 ENST00000381140 Transcription factor IIIA(Factor A) (TFIIIA). [Source: Uniprot/SWISSPROT; Acc: Q92664][ENST00000381140] NM_003145 SSR2 Homo sapiens signal sequence receptor,beta (translocon-associated protein beta) (SSR2), mRNA [NM_003145]THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homo sapiens} (exp= −1; wgp = 0; cg = 0), partial (42%) [THC2533996] NM_001344 DAD1 Homosapiens defender against cell death 1 (DAD1), mRNA [NM_001344]A_24_P255252 A_24_P255252 Unknown NM_002954 RPS27A Homo sapiensribosomal protein S27a (RPS27A), mRNA [NM_002954] NM_145808 MTPN Homosapiens myotrophin (MTPN), mRNA [NM_145808] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] NM_020240CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcriptvariant 1, mRNA [NM_020240] NM_001016 RPS12 Homo sapiens ribosomalprotein S12 (RPS12), mRNA [NM_001016] NM_175738 RAB37 Homo sapiensRAB37, member RAS oncogene family (RAB37), transcript variant 3, mRNA[NM_175738] A_24_P170147 A_24_P170147 Unknown NM_007104 RPL10A Homosapiens ribosomal protein L10a (RPL10A), mRNA [NM_007104] XR_015944LOC731681 PREDICTED: Homo sapiens similar to 60S ribosomal protein L9(LOC731681), mRNA [XR_015944] XR_018963 LOC442237 PREDICTED: Homosapiens similar to 40S ribosomal protein S7 (S8) (LOC442237), mRNA[XR_018963] NM_021149 COTL1 Homo sapiens coactosin-like 1(Dictyostelium) (COTL1), mRNA [NM_021149] NM_003295 TPT1 Homo sapienstumor protein, translationally-controlled 1 (TPT1), mRNA [NM_003295]NM_016269 LEF1 Homo sapiens lymphoid enhancer-binding factor 1 (LEF1),mRNA [NM_016269] NM_016274 PLEKHO1 Homo sapiens pleckstrin homologydomain containing, family O member 1 (PLEKHO1), mRNA [NM_016274]NM_006830 UQCR Homo sapiens ubiquinol-cytochrome c reductase, 6.4 kDasubunit (UQCR), mRNA [NM_006830] NM_001404 EEF1G Homo sapiens eukaryotictranslation elongation factor 1 gamma (EEF1G), mRNA [NM_001404]A_24_P755505 A_24_P755505 Unknown ENST00000078131 ENST00000078131OTTHUMP00000016594. [Source: Uniprot/SPTREMBL; Acc: Q9NU98][ENST00000078131] NM_021103 TMSB10 Homo sapiens thymosin, beta 10(TMSB10), mRNA [NM_021103] XR_018554 LOC402219 PREDICTED: Homo sapienssimilar to ribosomal protein L5 (LOC402219), mRNA [XR_018554] NM_033625RPL34 Homo sapiens ribosomal protein L34 (RPL34), transcript variant 2,mRNA [NM_033625] XR_015936 LOC731457 PREDICTED: Homo sapiens similar toribosomal protein S27a (LOC731457), mRNA [XR_015936] AF147412 AF147412Homo sapiens full length insert cDNA clone YP59C02. [AF147412] NM_001011RPS7 Homo sapiens ribosomal protein S7 (RPS7), mRNA [NM_001011]A_24_P730256 A_24_P730256 Unknown A_24_P587803 A_24_P587803 UnknownNM_016270 KLF2 Homo sapiens Kruppel-like factor 2 (lung) (KLF2), mRNA[NM_016270] NM_015414 RPL36 Homo sapiens ribosomal protein L36 (RPL36),transcript variant 2, mRNA [NM_015414] XR_017130 LOC158345 PREDICTED:Homo sapiens similar to ribosomal protein L4 (LOC158345), mRNA[XR_017130] XR_018222 RPL31P4 PREDICTED: Homo sapiens ribosomal proteinL31 pseudogene 4 (RPL31P4), mRNA [XR_018222] BC028083 TRBV5-4 Homosapiens T cell receptor beta variable 5-4, mRNA (cDNA clone MGC: 40031IMAGE: 5217067), complete cds. [BC028083] NM_000997 RPL37 Homo sapiensribosomal protein L37 (RPL37), mRNA [NM_000997] A_24_P367063A_24_P367063 Unknown NM_001010 RPS6 Homo sapiens ribosomal protein S6(RPS6), mRNA [NM_001010] THC2553216 THC2553216 HUMRRL3A ribosomalprotein L3 {Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (24%)[THC2553216] NM_033625 RPL34 Homo sapiens ribosomal protein L34 (RPL34),transcript variant 2, mRNA [NM_033625] A_24_P685729 A_24_P685729 UnknownNM_022551 RPS18 Homo sapiens ribosomal protein S18 (RPS18), mRNA[NM_022551] NM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25),mRNA [NM_001028] NM_000996 RPL35A Homo sapiens ribosomal protein L35a(RPL35A), mRNA [NM_000996] XR_018695 RPL31P10 PREDICTED: Homo sapienssimilar to ribosomal protein L31 (LOC390283), mRNA [XR_018695]A_24_P144163 A_24_P144163 Unknown A_24_P238427 A_24_P238427 UnknownAK092748 RP3-377H14.5 Homo sapiens cDNA FLJ35429 fis, cloneSMINT2002126. [AK092748] THC2560098 THC2560098 S35960 C-terminal {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (64%) [THC2560098]DW451363 DW451363 HHAGE004093 Human liver regeneration after partialhepatectomy Homo sapiens cDNA, mRNA sequence [DW451363] A_24_P324224A_24_P324224 Unknown NM_000970 RPL6 Homo sapiens ribosomal protein L6(RPL6), transcript variant 2, mRNA [NM_000970] ENST00000356196 hCG_26523PREDICTED: Homo sapiens similar to 60S ribosomal protein L26(LOC646161), mRNA [XR_018048] NM_203477 MGC70863 Homo sapiens similar toRPL23AP7 protein (MGC70863), transcript variant 1, mRNA [NM_203477]ENST00000356196 hCG_26523 PREDICTED: Homo sapiens similar to 60Sribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)(LOC400055), mRNA [XM_374987] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] NM_000454SOD1 Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateralsclerosis 1 (adult)) (SOD1), mRNA [NM_000454] NM_001013 RPS9 Homosapiens ribosomal protein S9 (RPS9), mRNA [NM_001013] XR_018048LOC646161 PREDICTED: Homo sapiens similar to 60S ribosomal protein L26(LOC646161), mRNA [XR_018048] THC2584902 THC2584902 Q5M9L9_MOUSE(Q5M9L9) Ribosomal protein S8, partial (73%) [THC2584902] XR_015398LOC730747 PREDICTED: Homo sapiens similar to 60S ribosomal protein L14(CAG-ISL 7) (LOC730747), mRNA [XR_015398] XR_019277 LOC391719 PREDICTED:Homo sapiens similar to ribosomal protein L19 (LOC391719), mRNA[XR_019277] XR_019597 LOC401863 PREDICIED: Homo sapiens similar toribosomal protein L10a (LOC401863), mRNA [XR_019597] AK098605 AK098605Homo sapiens cDNA FLJ25739 fis, clone TST05834. [AK098605] A_24_P127442A_24_P127442 Unknown NM_203495 COMMD6 Homo sapiens COMM domaincontaining 6 (COMMD6), transcript variant 2, mRNA [NM_203495] NM_153236GIMAP7 Homo sapiens GTPase, IMAP family member 7 (GIMAP7), mRNA[NM_153236] XM_935576 LOC641827 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 beta 2 (LOC641827), mRNA[XM_935576] NR_001577 NME2P1 Homo sapiens non-metastatic cells 2,protein (NM23B) expressed in pseudogene 1 (NME2P1) on chromosome 12[NR_001577] XR_015767 LOC731224 PREDICTED: Homo sapiens similar to 60Sribosomal protein L9 (LOC731224), mRNA [XR_015767] NM_007104 RPL10A Homosapiens ribosomal protein L10a (RPL10A), mRNA [NM_007104] NM_003295 TPT1Homo sapiens tumor protein, translationally-controlled 1 (TPT1), mRNA[NM_003295] AK124741 AK124741 Homo sapiens cDNA FLJ42751 fis, cloneBRAWH3000491, moderately similar to 40S ribosomal protein S12.[AK124741] NM_005617 RPS14 Homo sapiens ribosomal protein S14 (RPS14),transcript variant 3, mRNA [NM_005617] NM_000986 RPL24 Homo sapiensribosomal protein L24 (RPL24), mRNA [NM_000986] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] XM_001125895LOC730452 PREDICTED: Homo sapiens similar to 60S ribosomal protein L7(LOC730452), mRNA [XM_001125895] NM_001011 RPS7 Homo sapiens ribosomalprotein S7 (RPS7), mRNA [NM_001011] XR_018994 LOC391181 PREDICTED: Homosapiens similar to 60S ribosomal protein L6 (TAX-responsive enhancerelement-binding protein 107) (TAXREB107) (Neoplasm-related protein C140)(LOC391181), mRNA [XR_018994] A_24_P332441 A_24_P332441 UnknownNM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcriptvariant 1, mRNA [NM_000967] NM_006013 RPL10 Homo sapiens ribosomalprotein L10 (RPL10), mRNA [NM_006013] NM_000982 RPL21 Homo sapiensribosomal protein L21 (RPL21), mRNA [NM_000982] XR_018341 LOC390413PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC390413),mRNA [XR_018341] XR_018054 LOC392878 PREDICTED: Homo sapienshypothetical LOC392878 (LOC392878), mRNA [XR_018054] NM_006013 RPL10Homo sapiens ribosomal protein L10 (RPL10), mRNA [NM_006013] NM_001011RPS7 Homo sapiens ribosomal protein S7 (RPS7), mRNA [NM_001011]ENST00000332696 ENST00000332696 similar to 60S ribosomal protein L23a(LOC644384), mRNA [Source: RefSeq dna; Acc: XR_017413] [ENST00000332696]NM_006360 PCID1 Homo sapiens PCI domain containing 1 (herpesvirus entrymediator) (PCID1), mRNA [NM_006360] A_24_P204474 A_24_P204474 UnknownA_32_P208856 A_32_P208856 Unknown NM_001404 EEF1G Homo sapienseukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] ENST00000313620 LOC342994 PREDICTED: Homo sapiens similar toribosomal protein L34 (LOC342994), mRNA [XM_938484] A_24_P126902A_24_P126902 Unknown THC2506377 THC2506377 HSU02032 ribosomal proteinL23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (92%)[THC2506377] NM_000998 RPL37A Homo sapiens ribosomal protein L37a(RPL37A), mRNA [NM_000998] NM_000454 SOD1 Homo sapiens superoxidedismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1),mRNA [NM_000454] NM_005340 HINT1 Homo sapiens histidine triad nucleotidebinding protein 1 (HINT1), mRNA [NM_005340] NM_006013 RPL10 Homo sapiensribosomal protein L10 (RPL10), mRNA [NM_006013] NM_080746 RPL10L Homosapiens ribosomal protein L10-like (RPL10L), mRNA [NM_080746]A_24_P50489 A_24_P50489 Unknown XR_019242 LOC402149 PREDICTED: Homosapiens similar to ribosomal protein L28 (LOC402149), mRNA [XR_019242]NM_002568 PABPC1 Homo sapiens poly(A) binding protein, cytoplasmic 1(PABPC1), mRNA [NM_002568] NP1252191 NP1252191GB|AACC02000041.1|EAL24419.1 similar to 60S ribosomal protein L32 [Homosapiens] [NP1252191] NM_000997 RPL37 Homo sapiens ribosomal protein L37(RPL37), mRNA [NM_000997] NM_000986 RPL24 Homo sapiens ribosomal proteinL24 (RPL24), mRNA [NM_000986] XR_019052 LOC391738 PREDICTED: Homosapiens similar to 60S ribosomal protein L29 (Cell surfaceheparin-binding protein HIP) (LOC391738), mRNA [XR_019052] XR_018303LOC648378 PREDICTED: Homo sapiens similar to ribosomal protein S14(LOC648378), mRNA [XR_018303] XM_928025 LOC644937 PREDICTED: Homosapiens similar to 60S ribosomal protein L10 (QM protein) (Tumorsuppressor QM) (Laminin receptor homolog) (LOC644937), mRNA [XM_928025]AL137354 AL137354 Homo sapiens mRNA; cDNA DKFZp434A0326 (from cloneDKFZp434A0326). [AL137354] XM_930195 hCG_18290 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L32 (LOC644907), mRNA [XM_930195]NM_001080544 LOC653314 Homo sapiens similar to ribosomal protein L19(LOC653314), mRNA [NM_001080544] ENST00000333351 ENST00000333351PREDICTED: Homo sapiens hypothetical LOC391504 (LOC391504), mRNA[XR_018627] NM_173833 SCARA5 Homo sapiens scavenger receptor class A,member 5 (putative) (SCARA5), mRNA [NM_173833] NM_182688 UBE2G2 Homosapiens ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)(UBE2G2), transcript variant 2, mRNA [NM_182688] AK000420 AK000420 Homosapiens cDNA FLJ20413 fis, clone KAT02170. [AK000420] NM_024812 BAALCHomo sapiens brain and acute leukemia, cytoplasmic (BAALC), transcriptvariant 1, mRNA [NM_024812] XM_372498 LOC390427 PREDICTED: Homo sapienssimilar to TBP-associated factor 15 isoform 1 (LOC390427), mRNA[XM_372498] THC2718728 THC2718728 Unknown NM_198253 TERT Homo sapienstelomerase reverse transcriptase (TERT), transcript variant 1, mRNA[NM_198253] NM_002307 LGALS7 Homo sapiens lectin, galactoside-binding,soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307] ENST00000248668 LRFN1Leucine-rich repeat and fibronectin type III domain-containing protein 1(Fragment). [Source: Uniprot/SPTREMBL; Acc: Q9P244] [ENST00000248668]ENST00000325151 ENST00000325151 Small inducible cytokine A27 precursor(CCL27) (CC chemokine ILC) (IL-11 R-alpha-locus chemokine) (Skinkine)(ESkine) (Cutaneous T-cell-attracting chemokine) (CTACK). [Source:Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_006266 RALGDS Homosapiens ral guanine nucleotide dissociation stimulator (RALGDS),transcript variant 1, mRNA [NM_006266] NM_001138 AGRP Homo sapiensagouti related protein homolog (mouse) (AGRP), transcript variant 1,mRNA [NM_001138] NM_207377 UNQ9438 Homo sapiens TIMM9 (UNQ9438), mRNA[NM_207377] NM_015088 TNRC6B Homo sapiens trinucleotide repeatcontaining 6B (TNRC6B), transcript variant 1, mRNA [NM_015088] NM_175734C17orf74 Homo sapiens chromosome 17 open reading frame 74 (C17orf74),mRNA [NM_175734] NM_004750 CRLF1 Homo sapiens cytokine receptor-likefactor 1 (CRLF1), mRNA [NM_004750] NM_003508 FZD9 Homo sapiens frizzledhomolog 9 (Drosophila) (FZD9), mRNA [NM_003508] AA418814 AA418814AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3′, mRNA sequence [AA418814] NM_203374 ZNF784 Homo sapiens zincfinger protein 784 (ZNF784), mRNA [NM_203374] ENST00000380739 SERPINB1Leukocyte elastase inhibitor (LEI) (Serpin B1) (Monocyte/neutrophilelastase inhibitor) (M/NEI) (EI). [Source: Uniprot/SWISSPROT; Acc:P30740] [ENST00000380739] NM_012183 FOXD3 Homo sapiens forkhead box D3(FOXD3), mRNA [NM_012183] NM_019105 TNXB Homo sapiens tenascin XB(TNXB), transcript variant XB, mRNA [NM_019105] ENST00000360514ENST00000360514 Homo sapiens hypothetical LOC339483, mRNA (cDNA cloneMGC: 52427 IMAGE: 4872239), complete cds. [BC041632] NM_138763 BAX Homosapiens BCL2-associated X protein (BAX), transcript variant delta, mRNA[NM_138763] NM_203304 RKHD1 Homo sapiens ring finger and KH domaincontaining 1 (RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiensleucine-rich repeat-containing G protein-coupled receptor 4 (LGR4), mRNA[NM_018490] CV575560 CV575560 oe37f10.y1 Human keratoconus cornea,unamplified, (od [CV575560]

TABLE 13 Gene list generated at the inclusion criteria of p ≦ 0.05 andthe log-median-ratio being below being at least “1” or above, or being“−1” or below. GenBank Accession GeneName Description NM_002619 PF4 Homosapiens platelet factor 4 (chemokine (C—X—C motif) ligand 4) (PF4), mRNA[NM_002619] NM_001039567 RPS4Y2 Homo sapiens ribosomal protein S4,Y-linked 2 (RPS4Y2), mRNA [NM_001039567] NM_183049 TMSL3 Homo sapiensthymosin-like 3 (TMSL3), mRNA [NM_183049] NM_001008 RPS4Y1 Homo sapiensribosomal protein S4, Y-linked 1 (RPS4Y1), mRNA [NM_001008] NM_004126GNG11 Homo sapiens guanine nucleotide binding protein (G protein), gamma11 (GNG11), mRNA [NM_004126] NM_002985 CCL5 Homo sapiens chemokine (C-Cmotif) ligand 5 (CCL5), mRNA [NM_002985] NM_002704 PPBP Homo sapienspro-platelet basic protein (chemokine (C—X—C motif) ligand 7) (PPBP),mRNA [NM_002704] NM_183049 TMSL3 Homo sapiens thymosin-like 3 (TMSL3),mRNA [NM_183049] A_24_P530977 A_24_P530977 Unknown NM_004048 B2M Homosapiens beta-2-microglobulin (B2M), mRNA [NM_004048] ENST00000334647ENST00000334647 Thymosin-like 4. [Source: Uniprot/SPTREMBL; Acc: Q5T4B6][ENST00000334647] NM_004907 IER2 Homo sapiens immediate early response 2(IER2), mRNA [NM_004907] NM_004048 B2M Homo sapiens beta-2-microglobulin(B2M), mRNA [NM_004048] NM_001005339 RGS10 Homo sapiens regulator ofG-protein signalling 10 (RGS10), transcript variant 1, mRNA[NM_001005339] NM_201397 GPX1 Homo sapiens glutathione peroxidase 1(GPX1), transcript variant 2, mRNA [NM_201397] NM_006176 NRGN Homosapiens neurogranin (protein kinase C substrate, RC3) (NRGN), mRNA[NM_006176] NM_015646 RAP1B Homo sapiens RAP1B, member of RAS oncogenefamily (RAP1B), transcript variant 1, mRNA [NM_015646] NM_130782 RGS18Homo sapiens regulator of G-protein signalling 18 (RGS18), mRNA[NM_130782] NM_015714 G0S2 Homo sapiens G0/G1switch 2 (G0S2), mRNA[NM_015714] NM_002490 NDUFA6 Homo sapiens NADH dehydrogenase(ubiquinone) 1 alpha subcomplex, 6, 14 kDa (NDUFA6), nuclear geneencoding mitochondrial protein, mRNA [NM_002490] AL049447 AL049447 Homosapiens mRNA; cDNA DKFZp586A0722 (from clone DKFZp586A0722). [AL049447]NM_031286 SH3BGRL3 Homo sapiens SH3 domain binding glutamic acid-richprotein like 3 (SH3BGRL3), mRNA [NM_031286] NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] ENST00000375806 C6orf25 G6bprotein precursor. [Source: Uniprot/SWISSPROT; Acc: O95866][ENST00000375806] NM_021109 TMSB4X Homo sapiens thymosin, beta 4,X-linked (TMSB4X), mRNA [NM_021109] NM_000407 GP1BB Homo sapiensglycoprotein Ib (platelet), beta polypeptide (GP1BB), mRNA [NM_000407]BC000845 BC000845 Homo sapiens cDNA clone IMAGE: 3457769, partial cds.[BC000845] NM_012329 MMD Homo sapiens monocyte to macrophagedifferentiation-associated (MMD), mRNA [NM_012329] AK025280 THRAP2 Homosapiens cDNA: FLJ21627 fis, clone COL08058. [AK025280] NM_004048 B2MHomo sapiens beta-2-microglobulin (B2M), mRNA [NM_004048] NM_002620PF4V1 Homo sapiens platelet factor 4 variant 1 (PF4V1), mRNA [NM_002620]NM_032489 ACRBP Homo sapiens acrosin binding protein (ACRBP), mRNA[NM_032489] NM_001004 RPLP2 Homo sapiens ribosomal protein, large, P2(RPLP2), mRNA [NM_001004] NM_033251 RPL13 Homo sapiens ribosomal proteinL13 (RPL13), transcript variant 2, mRNA [NM_033251] NM_002073 GNAZ Homosapiens guanine nucleotide binding protein (G protein), alpha zpolypeptide (GNAZ), mRNA [NM_002073] NM_203339 CLU Homo sapiensclusterin (CLU), transcript variant 2, mRNA [NM_203339] NM_014857RABGAP1L Homo sapiens RAB GTPase activating protein 1-like (RABGAP1L),transcript variant 1, mRNA [NM_014857] ENST00000383061 ENST00000383061PREDICTED: Homo sapiens similar to myosin regulatory light chain-like(LOC442204), mRNA [XM_498088] NM_004152 OAZ1 Homo sapiens ornithinedecarboxylase antizyme 1 (OAZ1), mRNA [NM_004152] NM_004907 IER2 Homosapiens immediate early response 2 (IER2), mRNA [NM_004907] NM_001803CD52 Homo sapiens CD52 molecule (CD52), mRNA [NM_001803] NM_004048 B2MHomo sapiens beta-2-microglobulin (B2M), mRNA [NM_004048] NM_145113 MAXHomo sapiens MYC associated factor X (MAX), transcript variant 3, mRNA[NM_145113] NM_002954 RPS27A Homo sapiens ribosomal protein S27a(RPS27A), mRNA [NM_002954] A_24_P144383 A_24_P144383 Unknown NM_006471MRCL3 Homo sapiens myosin regulatory light chain MRCL3 (MRCL3), mRNA[NM_006471] NM_014380 NGFRAP1 Homo sapiens nerve growth factor receptor(TNFRSF16) associated protein 1 (NGFRAP1), transcript variant 3, mRNA[NM_014380] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_004048 B2M Homosapiens beta-2-microglobulin (B2M), mRNA [NM_004048] NM_001402 EEF1A1Homo sapiens eukaryotic translation elongation factor 1 alpha 1(EEF1A1), mRNA [NM_001402] NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] AY029066 AY029066 Homosapiens Humanin (HN1) mRNA, complete cds. [AY029066] NM_001030 RPS27Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA[NM_001030] NM_080425 GNAS Homo sapiens GNAS complex locus (GNAS),transcript variant 2, mRNA [NM_080425] NM_001032 RPS29 Homo sapiensribosomal protein S29 (RPS29), transcript variant 1, mRNA [NM_001032]NM_014372 RNF11 Homo sapiens ring finger protein 11 (RNF11), mRNA[NM_014372] NM_004048 B2M Homo sapiens beta-2-microglobulin (B2M), mRNA[NM_004048] NM_007262 PARK7 Homo sapiens Parkinson disease (autosomalrecessive, early onset) 7 (PARK7), mRNA [NM_007262] NM_001012 RPS8 Homosapiens ribosomal protein S8 (RPS8), mRNA [NM_001012] NM_006000 TUBA4AHomo sapiens tubulin, alpha 4a (TUBA4A), mRNA [NM_006000] NM_005594 NACAHomo sapiens nascent-polypeptide-associated complex alpha polypeptide(NACA), mRNA [NM_005594] XR_017498 LOC645693 PREDICTED: Homo sapienssimilar to eukaryotic translation elongation factor 1 alpha 2(LOC645693), mRNA [XR_017498] NM_006597 HSPA8 Homo sapiens heat shock 70kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597] NM_001778CD48 Homo sapiens CD48 molecule (CD48), mRNA [NM_001778] NM_016489 NT5C3Homo sapiens 5′-nucleotidase, cytosolic III (NT5C3), transcript variant3, mRNA [NM_016489] ENST00000361789 CYTB Cytochrome b. [Source:Uniprot/SWISSPROT; Acc: P00156] [ENST00000361789] NM_001800 CDKN2D Homosapiens cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)(CDKN2D), transcript variant 1, mRNA [NM_001800] NM_001017 RPS13 Homosapiens ribosomal protein S13 (RPS13), mRNA [NM_001017] NM_001030 RPS27Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA[NM_001030] NM_000968 RPL4 Homo sapiens ribosomal protein L4 (RPL4),mRNA [NM_000968] NM_004657 SDPR Homo sapiens serum deprivation response(phosphatidylserine binding protein) (SDPR), mRNA [NM_004657] NM_002032FTH1 Homo sapiens ferritin, heavy polypeptide 1 (FTH1), mRNA [NM_002032]NM_002032 FTH1 Homo sapiens ferritin, heavy polypeptide 1 (FTH1), mRNA[NM_002032] XR_018386 LOC392358 PREDICTED: Homo sapiens similar to 40Sribosomal protein S6 (LOC392358), mRNA [XR_018386] NM_002436 MPP1 Homosapiens membrane protein, palmitoylated 1, 55 kDa (MPP1), mRNA[NM_002436] A_24_P229756 A_24_P229756 Unknown NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] NM_024299 C20orf149 Homosapiens chromosome 20 open reading frame 149 (C20orf149), mRNA[NM_024299] NM_002945 RPA1 Homo sapiens replication protein A1, 70 kDa(RPA1), mRNA [NM_002945] NM_002032 FTH1 Homo sapiens ferritin, heavypolypeptide 1 (FTH1), mRNA [NM_002032] THC2544911 THC2544911 MUSEFTUelongation factor Tu {Mus musculus} (exp = −1; wgp = 0; cg = 0), partial(37%) [THC2544911] NM_001017 RPS13 Homo sapiens ribosomal protein S13(RPS13), mRNA [NM_001017] NM_002107 H3F3A Homo sapiens H3 histone,family 3A (H3F3A), mRNA [NM_002107] NM_001005 RPS3 Homo sapiensribosomal protein S3 (RPS3), mRNA [NM_001005] NM_021104 RPL41 Homosapiens ribosomal protein L41 (RPL41), transcript variant 1, mRNA[NM_021104] NM_000981 RPL19 Homo sapiens ribosomal protein L19 (RPL19),mRNA [NM_000981] THC2527647 THC2527647 Q59GY2_HUMAN (Q59GY2) Ribosomalprotein L4 variant (Fragment), partial (51%) [THC2527647] A_24_P929974A_24_P929974 Unknown NM_002300 LDHB Homo sapiens lactate dehydrogenase B(LDHB), mRNA [NM_002300] NM_152793 C7orf41 Homo sapiens chromosome 7open reading frame 41 (C7orf41), mRNA [NM_152793] NM_033251 RPL13 Homosapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] NM_001031 RPS28 Homo sapiens ribosomal protein S28 (RPS28),mRNA [NM_001031] M36647 UQCRH Homo sapiens mitochondrial hinge proteinprecursor, mRNA, complete cds. [M36647] NM_003973 RPL14 Homo sapiensribosomal protein L14 (RPL14), transcript variant 2, mRNA [NM_003973]NM_000978 RPL23 Homo sapiens ribosomal protein L23 (RPL23), mRNA[NM_000978] NM_003118 SPARC Homo sapiens secreted protein, acidic,cysteine-rich (osteonectin) (SPARC), mRNA [NM_003118] NM_033251 RPL13Homo sapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] NM_001003 RPLP1 Homo sapiens ribosomal protein, large, P1(RPLP1), transcript variant 1, mRNA [NM_001003] NM_001568 EIF3S6 Homosapiens eukaryotic translation initiation factor 3, subunit 6 48 kDa(EIF3S6), mRNA [NM_001568] A_24_P392195 A_24_P392195 Unknown NM_000129F13A1 Homo sapiens coagulation factor XIII, A1 polypeptide (F13A1), mRNA[NM_000129] NM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25),mRNA [NM_001028] NM_003756 EIF3S3 Homo sapiens eukaryotic translationinitiation factor 3, subunit 3 gamma, 40 kDa (EIF3S3), mRNA [NM_003756]NM_001032 RPS29 Homo sapiens ribosomal protein S29 (RPS29), transcriptvariant 1, mRNA [NM_001032] NM_002107 H3F3A Homo sapiens H3 histone,family 3A (H3F3A), mRNA [NM_002107] A_24_P238426 A_24_P238426 UnknownNM_018447 TMEM111 Homo sapiens transmembrane protein 111 (TMEM111), mRNA[NM_018447] A_24_P127051 A_24_P127051 Unknown BX096698 BX096698 BX096698Soares breast 2NbHBst Homo sapiens cDNA clone IMAGp998E11242, mRNAsequence [BX096698] XR_017260 LOC646710 PREDICTED: Homo sapienshypothetical LOC646710 (LOC646710), mRNA [XR_017260] A_24_P333112A_24_P333112 Unknown NM_001003 RPLP1 Homo sapiens ribosomal protein,large, P1 (RPLP1), transcript variant 1, mRNA [NM_001003] NM_002823 PTMAHomo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA[NM_002823] NM_033251 RPL13 Homo sapiens ribosomal protein L13 (RPL13),transcript variant 2, mRNA [NM_033251] XR_017294 LOC646949 PREDICTED:Homo sapiens similar to ribosomal protein L23 (LOC646949), mRNA[XR_017294] XR_016779 LOC440311 PREDICTED: Homo sapiens similar toGlioma tumor suppressor candidate region gene 2 protein (p60)(LOC440311), mRNA [XR_016779] NM_002085 GPX4 Homo sapiens glutathioneperoxidase 4 (phospholipid hydroperoxidase) (GPX4), transcript variant1, mRNA [NM_002085] NM_000993 RPL31 Homo sapiens ribosomal protein L31(RPL31), mRNA [NM_000993] XR_015548 LOC729449 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L7 (LOC729449), mRNA [XR_015548]NM_001964 EGR1 Homo sapiens early growth response 1 (EGR1), mRNA[NM_001964] NM_199290 NACA2 Homo sapiens nascent-polypeptide-associatedcomplex alpha polypeptide-like (NACAL), mRNA [NM_199290] BC052613LOC728131 Homo sapiens cDNA clone MGC: 59872 IMAGE: 6301163, completecds. [BC052613] A_24_P306968 A_24_P306968 Unknown A_32_P49392A_32_P49392 Unknown XM_497657 LOC441876 PREDICTED: Homo sapiens similarto 40S ribosomal protein S16, transcript variant 1 (LOC441876), mRNA[XM_497657] NM_001025 RPS23 Homo sapiens ribosomal protein S23 (RPS23),mRNA [NM_001025] BU956542 BU956542 BU956542 AGENCOURT_10615527NIH_MGC_107 Homo sapiens cDNA clone IMAGE: 6730153 5′, mRNA sequence[BU956542] AK027315 AK027315 Homo sapiens cDNA FLJ14409 fis, cloneHEMBA1004408, moderately similar to PEPTIDYL-PROLYL CIS-TRANS ISOMERASE10 (EC 5.2.1.8). [AK027315] NM_001997 FAU Homo sapiensFinkel-Biskis-Reilly murine sarcoma virus (FBR- MuSV) ubiquitouslyexpressed (fox derived); ribosomal protein S30 (FAU), mRNA [NM_001997]NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8 (HSPA8),transcript variant 1, mRNA [NM_006597] NM_007285 GABARAPL2 Homo sapiensGABA(A) receptor-associated protein-like 2 (GABARAPL2), mRNA [NM_007285]NM_001006 RPS3A Homo sapiens ribosomal protein S3A (RPS3A), mRNA[NM_001006] NM_001402 EEF1A1 Homo sapiens eukaryotic translationelongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_001568 EIF3S6Homo sapiens eukaryotic translation initiation factor 3, subunit 6 48kDa (EIF3S6), mRNA [NM_001568] NM_001436 FBL Homo sapiens fibrillarin(FBL), mRNA [NM_001436] NM_000975 RPL11 Homo sapiens ribosomal proteinL11 (RPL11), mRNA [NM_000975] NM_033546 MRLC2 Homo sapiens myosinregulatory light chain MRLC2 (MRLC2), mRNA [NM_033546] NR_003038 SNHG5Homo sapiens small nucleolar RNA host gene (non-protein coding) 5(SNHG5) on chromosome 6 [NR_003038] A_32_P128781 A_32_P128781 UnknownXR_018063 LOC392030 PREDICTED: Homo sapiens hypothetical LOC392030(LOC392030), mRNA [XR_018063] NM_003407 ZFP36 Homo sapiens zinc fingerprotein 36, C3H type, homolog (mouse) (ZFP36), mRNA [NM_003407]A_24_P298835 A_24_P298835 Unknown THC2740013 THC2740013 Q2U8W6_ASPOR(Q2U8W6) Predicted protein, partial (14%) [THC2740013] ENST00000343149ENST00000343149 Unknown A_23_P200955 A_23_P200955 Unknown A_24_P341376A_24_P341376 Unknown NM_003498 SNN Homo sapiens stannin (SNN), mRNA[NM_003498] NM_080392 PTP4A2 Homo sapiens protein tyrosine phosphatasetype IVA, member 2 (PTP4A2), transcript variant 2, mRNA [NM_080392]NM_020152 C21orf7 Homo sapiens chromosome 21 open reading frame 7(C21orf7), mRNA [NM_020152] NM_213611 SLC25A3 Homo sapiens solutecarrier family 25 (mitochondrial carrier; phosphate carrier), member 3(SLC25A3), nuclear gene encoding mitochondrial protein, transcriptvariant 3, mRNA [NM_213611] NM_003279 TNNC2 Homo sapiens troponin C type2 (fast) (TNNC2), mRNA [NM_003279] ENST00000312528 ENST00000312528Unknown NM_015710 GLTSCR2 Homo sapiens glioma tumor suppressor candidateregion gene 2 (GLTSCR2), mRNA [NM_015710] NR_002205 FTHL12 Homo sapiensferritin, heavy polypeptide-like 12 (FTHL12) on chromosome 9 [NR_002205]NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1alpha 1 (EEF1A1), mRNA [NM_001402] AY029066 AY029066 Homo sapiensHumanin (HN1) mRNA, complete cds. [AY029066] NM_025228 TRAF3IP3 Homosapiens TRAF3 interacting protein 3 (TRAF3IP3), mRNA [NM_025228]NM_003529 HIST1H3A Homo sapiens histone cluster 1, H3a (HIST1H3A), mRNA[NM_003529] NM_002624 PFDN5 Homo sapiens prefoldin subunit 5 (PFDN5),transcript variant 1, mRNA [NM_002624] NM_005801 EIF1 Homo sapienseukaryotic translation initiation factor 1 (EIF1), mRNA [NM_005801]THC2567111 THC2567111 RL37_HUMAN (P61927) 60S ribosomal protein L37(G1.16), complete [THC2567111] ENST00000361789 CYTB Cytochrome b.[Source: Uniprot/SWISSPROT; Acc: P00156] [ENST00000361789] A_24_P160920A_24_P160920 Unknown A_24_P332292 A_24_P332292 Unknown NM_198969 AESHomo sapiens amino-terminal enhancer of split (AES), transcript variant1, mRNA [NM_198969] NM_000989 RPL30 Homo sapiens ribosomal protein L30(RPL30), mRNA [NM_000989] A_24_P878388 A_24_P878388 Unknown NM_003532HIST1H3E Homo sapiens histone cluster 1, H3e (HIST1H3E), mRNA[NM_003532] NM_001402 EEF1A1 Homo sapiens eukaryotic translationelongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_000989 RPL30Homo sapiens ribosomal protein L30 (RPL30), mRNA [NM_000989] XR_016879LOC388401 PREDICTED: Homo sapiens similar to 60S ribosomal protein L7(LOC388401), mRNA [XR_016879] CR620748 LOC729329 full-length cDNA cloneCS0DK011YI14 of HeLa cells Cot 25- normalized of Homo sapiens (human)[CR620748] NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3),transcript variant 1, mRNA [NM_000967] ENST00000337102 ENST0000033710240S ribosomal protein S21. [Source: Uniprot/SWISSPROT; Acc: P63220][ENST00000337102] A_24_P384239 A_24_P384239 Unknown NM_006263 PSME1 Homosapiens proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)(PSME1), transcript variant 1, mRNA [NM_006263] XR_018138 LOC392497PREDICTED: Homo sapiens similar to 40S ribosomal protein S6 (LOC392497),mRNA [XR_018138] NM_002341 LTB Homo sapiens lymphotoxin beta (TNFsuperfamily, member 3) (LTB), transcript variant 1, mRNA [NM_002341]NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcriptvariant 1, mRNA [NM_000967] A_24_P84408 A_24_P84408 Unknown NM_004566PFKFB3 Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase3 (PFKFB3), mRNA [NM_004566] A_24_P918875 A_24_P918875 Unknown NM_002121HLA-DPB1 Homo sapiens major histocompatibility complex, class II, DPbeta 1 (HLA-DPB1), mRNA [NM_002121] NM_007161 LST1 Homo sapiensleukocyte specific transcript 1 (LST1), transcript variant 1, mRNA[NM_007161] NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9),transcript variant 1, mRNA [NM_000661] NM_002107 H3F3A Homo sapiens H3histone, family 3A (H3F3A), mRNA [NM_002107] NM_000991 RPL28 Homosapiens ribosomal protein L28 (RPL28), mRNA [NM_000991] XR_018482LOC120318 PREDICTED: Homo sapiens similar to 40S ribosomal protein S6(LOC120318), mRNA [XR_018482] NM_003333 UBA52 Homo sapiens ubiquitinA-52 residue ribosomal protein fusion product 1 (UBA52), transcriptvariant 2, mRNA [NM_003333] NM_001006 RPS3A Homo sapiens ribosomalprotein S3A (RPS3A), mRNA [NM_001006] NM_001006 RPS3A Homo sapiensribosomal protein S3A (RPS3A), mRNA [NM_001006] NM_000661 RPL9 Homosapiens ribosomal protein L9 (RPL9), transcript variant 1, mRNA[NM_000661] NM_002952 RPS2 Homo sapiens ribosomal protein S2 (RPS2),mRNA [NM_002952] A_24_P650893 A_24_P650893 Unknown A_24_P50567A_24_P50567 Unknown A_24_P136011 A_24_P136011 Unknown A_24_P298238A_24_P298238 Unknown THC2541331 THC2541331 HSU02032 ribosomal proteinL23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (71%)[THC2541331] XR_018025 LOC641790 PREDICTED: Homo sapiens similar toribosomal protein L31 (LOC641790), mRNA [XR_018025] NM_014301 ISCU Homosapiens iron-sulfur cluster scaffold homolog (E. coli) (ISCU), nucleargene encoding mitochondrial protein, transcript variant 1, mRNA[NM_014301] NM_003295 TPT1 Homo sapiens tumor protein,translationally-controlled 1 (TPT1), mRNA [NM_003295] ENST00000332101ENST00000332101 PREDICTED: Homo sapiens similar to HIStone family member(his-72) (LOC391769), mRNA [XM_373079] NM_001867 COX7C Homo sapienscytochrome c oxidase subunit VIIc (COX7C), nuclear gene encodingmitochondrial protein, mRNA [NM_001867] BC018140 RPS21 Homo sapiensribosomal protein S21, mRNA (cDNA clone MGC: 9438 IMAGE: 3903320),complete cds. [BC018140] NM_005340 HINT1 Homo sapiens histidine triadnucleotide binding protein 1 (HINT1), mRNA [NM_005340] BC067891LOC645683 Homo sapiens cDNA clone MGC: 87657 IMAGE: 5271409, completecds. [BC067891] NM_001018108 SERF2 Homo sapiens small EDRK-rich factor 2(SERF2), mRNA [NM_001018108] ENST00000308989 ENST00000308989 PREDICTED:Homo sapiens similar to ribosomal protein L31 (LOC729005), mRNA[XM_001133428] A_24_P212726 A_24_P212726 Unknown NM_001028 RPS25 Homosapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] NM_000998 RPL37AHomo sapiens ribosomal protein L37a (RPL37A), mRNA [NM_000998] XR_015402LOC731170 PREDICTED: Homo sapiens similar to eukaryotic translationelongation factor 1 alpha 2 (LOC731170), mRNA [XR_015402] A_24_P340886A_24_P340886 Unknown NM_016480 PAIP2 Homo sapiens poly(A) bindingprotein interacting protein 2 (PAIP2), transcript variant 2, mRNA[NM_016480] THC2567891 THC2567891 Q6NXR8_HUMAN (Q6NXR8) Ribosomalprotein S3a, partial (91%) [THC2567891] ENST00000361227 ND3NADH-ubiquinone oxidoreductase chain 3 (EC 1.6.5.3) (NADH dehydrogenasesubunit 3). [Source: Uniprot/SWISSPROT; Acc: P03897] [ENST00000361227]XR_019376 LOC285260 PREDICTED: Homo sapiens similar to ribosomal proteinL31 (LOC285260), mRNA [XR_019376] ENST00000359449 ENST00000359449Sequence 237 from Patent WO0220754. [AX721277] NM_000988 RPL27 Homosapiens ribosomal protein L27 (RPL27), mRNA [NM_000988] A_24_P410256A_24_P410256 Unknown NM_021009 UBC Homo sapiens ubiquitin C (UBC), mRNA[NM_021009] XR_018975 LOC389644 PREDICTED: Homo sapiens similar toribosomal protein L5 (LOC389644), mRNA [XR_018975] XR_019168 LOC391847PREDICTED: Homo sapiens similar to ribosomal protein L19 (LOC391847),mRNA [XR_019168] NM_079423 MYL6 Homo sapiens myosin, light chain 6,alkali, smooth muscle and non-muscle (MYL6), transcript variant 2, mRNA[NM_079423] A_24_P505981 A_24_P505981 Unknown CD174733 CD174733 CD174733AGENCOURT_13961604 NIH_MGC_172 Homo sapiens cDNA 5′, mRNA sequence[CD174733] ENST00000240349 NACA3P PREDICTED: Homo sapiens similar tonascent polypeptide- associated complex alpha polypeptide (LOC389240),mRNA [XM_371715] A_24_P221375 A_24_P221375 Unknown NM_001743 CALM2 Homosapiens calmodulin 2 (phosphorylase kinase, delta) (CALM2), mRNA[NM_001743] NM_005801 EIF1 Homo sapiens eukaryotic translationinitiation factor 1 (EIF1), mRNA [NM_005801] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] NM_003746DYNLL1 Homo sapiens dynein, light chain, LC8-type 1 (DYNLL1), transcriptvariant 3, mRNA [NM_003746] XR_018231 LOC648027 PREDICTED: Homo sapienssimilar to Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma)(LOC648027), mRNA [XR_018231] NM_003753 EIF3S7 Homo sapiens eukaryotictranslation initiation factor 3, subunit 7 zeta, 66/67 kDa (EIF3S7),mRNA [NM_003753] NM_000978 RPL23 Homo sapiens ribosomal protein L23(RPL23), mRNA [NM_000978] BC001697 RPS15A Homo sapiens ribosomal proteinS15a, mRNA (cDNA clone MGC: 2466 IMAGE: 2967511), complete cds.[BC001697] NM_013234 EIF3S12 Homo sapiens eukaryotic translationinitiation factor 3, subunit 12 (EIF3S12), mRNA [NM_013234] NM_001022RPS19 Homo sapiens ribosomal protein S19 (RPS19), mRNA [NM_001022]A_24_P862524 A_24_P862524 Unknown NM_001007074 RPL32 Homo sapiensribosomal protein L32 (RPL32), transcript variant 3, mRNA [NM_001007074]NM_001861 COX4I1 Homo sapiens cytochrome c oxidase subunit IV isoform 1(COX4I1), mRNA [NM_001861] NM_006004 UQCRH Homo sapiensubiquinol-cytochrome c reductase hinge protein (UQCRH), mRNA [NM_006004]NM_006930 SKP1A Homo sapiens S-phase kinase-associated protein 1A (p19A)(SKP1A), transcript variant 1, mRNA [NM_006930] XR_019544 LOC652890PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC652890),mRNA [XR_019544] NM_021009 UBC Homo sapiens ubiquitin C (UBC), mRNA[NM_021009] A_24_P41979 A_24_P41979 Unknown NM_003746 DYNLL1 Homosapiens dynein, light chain, LC8-type 1 (DYNLL1), transcript variant 3,mRNA [NM_003746] NM_001344 DAD1 Homo sapiens defender against cell death1 (DAD1), mRNA [NM_001344] NM_000982 RPL21 Homo sapiens ribosomalprotein L21 (RPL21), mRNA [NM_000982] A_23_P210285 A_23_P210285 UnknownNM_002539 ODC1 Homo sapiens ornithine decarboxylase 1 (ODC1), mRNA[NM_002539] XR_019361 LOC442260 PREDICTED: Homo sapiens similar to 60Sribosomal protein L23a (LOC442260), mRNA [XR_019361] A_24_P289884A_24_P289884 Unknown NM_006357 UBE2E3 Homo sapiens ubiquitin-conjugatingenzyme E2E 3 (UBC4/5 homolog, yeast) (UBE2E3), transcript variant 1,mRNA [NM_006357] NM_000990 RPL27A Homo sapiens ribosomal protein L27a(RPL27A), mRNA [NM_000990] NM_003404 YWHAB Homo sapiens tyrosine3-monooxygenase/tryptophan 5- monooxygenase activation protein, betapolypeptide (YWHAB), transcript variant 1, mRNA [NM_003404] A_24_P135242A_24_P135242 Unknown NM_003973 RPL14 Homo sapiens ribosomal protein L14(RPL14), transcript variant 2, mRNA [NM_003973] XR_019386 LOC652558PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC652558),mRNA [XR_019386] NM_021009 UBC Homo sapiens ubiquitin C (UBC), mRNA[NM_021009] ENST00000381140 ENST00000381140 Transcription factor IIIA(Factor A) (TFIIIA). [Source: Uniprot/SWISSPROT; Acc: Q92664][ENST00000381140] NM_003145 SSR2 Homo sapiens signal sequence receptor,beta (translocon-associated protein beta) (SSR2), mRNA [NM_003145]NM_004905 PRDX6 Homo sapiens peroxiredoxin 6 (PRDX6), mRNA [NM_004905]THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homo sapiens} (exp= −1; wgp = 0; cg = 0), partial (42%) [THC2533996] NM_002796 PSMB4 Homosapiens proteasome (prosome, macropain) subunit, beta type, 4 (PSMB4),mRNA [NM_002796] NM_001344 DAD1 Homo sapiens defender against cell death1 (DAD1), mRNA [NM_001344] A_24_P255252 A_24_P255252 UnknownENST00000361453 ND2 NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3)(NADH dehydrogenase subunit 2). [Source: Uniprot/SWISSPROT; Acc: P03891][ENST00000361453] NM_002954 RPS27A Homo sapiens ribosomal protein S27a(RPS27A), mRNA [NM_002954] NM_079423 MYL6 Homo sapiens myosin, lightchain 6, alkali, smooth muscle and non-muscle (MYL6), transcript variant2, mRNA [NM_079423] NM_145808 MTPN Homo sapiens myotrophin (MTPN), mRNA[NM_145808] NM_003277 CLDN5 Homo sapiens claudin 5 (transmembraneprotein deleted in velocardiofacial syndrome) (CLDN5), mRNA [NM_003277]NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA[NM_000984] NM_020240 CDC42SE2 Homo sapiens CDC42 small effector 2(CDC42SE2), transcript variant 1, mRNA [NM_020240] NM_001016 RPS12 Homosapiens ribosomal protein S12 (RPS12), mRNA [NM_001016] NM_175738 RAB37Homo sapiens RAB37, member RAS oncogene family (RAB37), transcriptvariant 3, mRNA [NM_175738] A_24_P170147 A_24_P170147 Unknown NM_007104RPL10A Homo sapiens ribosomal protein L10a (RPL10A), mRNA [NM_007104]XR_015944 LOC731681 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L9 (LOC731681), mRNA [XR_015944] XR_018963 LOC442237 PREDICTED:Homo sapiens similar to 40S ribosomal protein S7 (S8) (LOC442237), mRNA[XR_018963] NM_021149 COTL1 Homo sapiens coactosin-like 1(Dictyostelium) (COTL1), mRNA [NM_021149] NM_003295 TPT1 Homo sapienstumor protein, translationally-controlled 1 (TPT1), mRNA [NM_003295]NM_016269 LEF1 Homo sapiens lymphoid enhancer-binding factor 1 (LEF1),mRNA [NM_016269] NM_016274 PLEKHO1 Homo sapiens pleckstrin homologydomain containing, family O member 1 (PLEKHO1), mRNA [NM_016274]NM_006830 UQCR Homo sapiens ubiquinol-cytochrome c reductase, 6.4 kDasubunit (UQCR), mRNA [NM_006830] NM_080425 GNAS Homo sapiens GNAScomplex locus (GNAS), transcript variant 2, mRNA [NM_080425] NM_001404EEF1G Homo sapiens eukaryotic translation elongation factor 1 gamma(EEF1G), mRNA [NM_001404] A_24_P755505 A_24_P755505 UnknownENST00000078131 ENST00000078131 OTTHUMP00000016594. [Source:Uniprot/SPTREMBL; Acc: Q9NU98] [ENST00000078131] NM_021103 TMSB10 Homosapiens thymosin, beta 10 (TMSB10), mRNA [NM_021103] XR_018554 LOC402219PREDICTED: Homo sapiens similar to ribosomal protein L5 (LOC402219),mRNA [XR_018554] NM_033625 RPL34 Homo sapiens ribosomal protein L34(RPL34), transcript variant 2, mRNA [NM_033625] NM_004152 OAZ1 Homosapiens ornithine decarboxylase antizyme 1 (OAZ1), mRNA [NM_004152]XR_015936 LOC731457 PREDICTED: Homo sapiens similar to ribosomal proteinS27a (LOC731457), mRNA [XR_015936] AF147412 AF147412 Homo sapiens fulllength insert cDNA clone YP59C02. [AF147412] NM_001011 RPS7 Homo sapiensribosomal protein S7 (RPS7), mRNA [NM_001011] A_24_P730256 A_24_P730256Unknown A_24_P587803 A_24_P587803 Unknown NM_016270 KLF2 Homo sapiensKruppel-like factor 2 (lung) (KLF2), mRNA [NM_016270] NM_015414 RPL36Homo sapiens ribosomal protein L36 (RPL36), transcript variant 2, mRNA[NM_015414] NM_001658 ARF1 Homo sapiens ADP-ribosylation factor 1(ARF1), transcript variant 4, mRNA [NM_001658] XR_017130 LOC158345PREDICTED: Homo sapiens similar to ribosomal protein L4 (LOC158345),mRNA [XR_017130] A_24_P281853 A_24_P281853 Unknown XR_018222 RPL31P4PREDICTED: Homo sapiens ribosomal protein L31 pseudogene 4 (RPL31P4),mRNA [XR_018222] XR_015278 LOC730588 PREDICTED: Homo sapiens similar tosuppressor of initiator codon mutations, related sequence 1 (LOC730588),mRNA [XR_015278] NM_003333 UBA52 Homo sapiens ubiquitin A-52 residueribosomal protein fusion product 1 (UBA52), transcript variant 2, mRNA[NM_003333] BC028083 TRBV5-4 Homo sapiens T cell receptor beta variable5-4, mRNA (cDNA clone MGC: 40031 IMAGE: 5217067), complete cds.[BC028083] NM_001101 ACTB Homo sapiens actin, beta (ACTB), mRNA[NM_001101] NM_000997 RPL37 Homo sapiens ribosomal protein L37 (RPL37),mRNA [NM_000997] A_24_P367063 A_24_P367063 Unknown NM_001010 RPS6 Homosapiens ribosomal protein S6 (RPS6), mRNA [NM_001010] THC2553216THC2553216 HUMRRL3A ribosomal protein L3 {Homo sapiens} (exp = −1; wgp =0; cg = 0), partial (24%) [THC2553216] NM_033625 RPL34 Homo sapiensribosomal protein L34 (RPL34), transcript variant 2, mRNA [NM_033625]A_24_P685729 A_24_P685729 Unknown NM_022551 RPS18 Homo sapiens ribosomalprotein S18 (RPS18), mRNA [NM_022551] NM_001028 RPS25 Homo sapiensribosomal protein S25 (RPS25), mRNA [NM_001028] NM_000996 RPL35A Homosapiens ribosomal protein L35a (RPL35A), mRNA [NM_000996] NM_003493HIST3H3 Homo sapiens histone cluster 3, H3 (HIST3H3), mRNA [NM_003493]BC089454 BC089454 Homo sapiens cDNA clone MGC: 105145 IMAGE: 30563285,complete cds. [BC089454] XR_018695 RPL31P10 PREDICTED: Homo sapienssimilar to ribosomal protein L31 (LOC390283), mRNA [XR_018695] NM_005184CALM3 Homo sapiens calmodulin 3 (phosphorylase kinase, delta) (CALM3),mRNA [NM_005184] A_24_P144163 A_24_P144163 Unknown A_24_P238427A_24_P238427 Unknown NM_000636 SOD2 Homo sapiens superoxide dismutase 2,mitochondrial (SOD2), nuclear gene encoding mitochondrial protein,transcript variant 1, mRNA [NM_000636] NM_004152 OAZ1 Homo sapiensornithine decarboxylase antizyme 1 (OAZ1), mRNA [NM_004152] AK092748RP3-377H14.5 Homo sapiens cDNA FLJ35429 fis, clone SMINT2002126.[AK092748] THC2560098 THC2560098 S35960 C-terminal {Homo sapiens} (exp =−1; wgp = 0; cg = 0), partial (64%) [THC2560098] NM_002121 HLA-DPB1 Homosapiens major histocompatibility complex, class II, DP beta 1(HLA-DPB1), mRNA [NM_002121] NM_002107 H3F3A Homo sapiens H3 histone,family 3A (H3F3A), mRNA [NM_002107] DW451363 DW451363 HHAGE004093 Humanliver regeneration after partial hepatectomy Homo sapiens cDNA, mRNAsequence [DW451363] A_24_P324224 A_24_P324224 Unknown NM_000970 RPL6Homo sapiens ribosomal protein L6 (RPL6), transcript variant 2, mRNA[NM_000970] ENST00000356196 hCG_26523 PREDICTED: Homo sapiens similar to60S ribosomal protein L26 (LOC646161), mRNA [XR_018048] NM_203477MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863), transcriptvariant 1, mRNA [NM_203477] ENST00000356196 hCG_26523 PREDICTED: Homosapiens similar to 60S ribosomal protein L26 (Silica-induced gene 20protein) (SIG-20) (LOC400055), mRNA [XM_374987] NM_004832 GSTO1 Homosapiens glutathione S-transferase omega 1 (GSTO1), mRNA [NM_004832]NM_005617 RPS14 Homo sapiens ribosomal protein S14 (RPS14), transcriptvariant 3, mRNA [NM_005617] NM_000454 SOD1 Homo sapiens superoxidedismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1),mRNA [NM_000454] A_23_P165819 A_23_P165819 Unknown NM_002298 LCP1 Homosapiens lymphocyte cytosolic protein 1 (L-plastin) (LCP1), mRNA[NM_002298] NM_001013 RPS9 Homo sapiens ribosomal protein S9 (RPS9),mRNA [NM_001013] XR_018048 LOC646161 PREDICTED: Homo sapiens similar to60S ribosomal protein L26 (LOC646161), mRNA [XR_018048] NM_005252 FOSHomo sapiens v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS),mRNA [NM_005252] THC2584902 THC2584902 Q5M9L9_MOUSE (Q5M9L9) Ribosomalprotein S8, partial (73%) [THC2584902] XR_015398 LOC730747 PREDICTED:Homo sapiens similar to 60S ribosomal protein L14 (CAG-ISL 7)(LOC730747), mRNA [XR_015398] XR_019277 LOC391719 PREDICTED: Homosapiens similar to ribosomal protein L19 (LOC391719), mRNA [XR_019277]XR_019597 LOC401863 PREDICTED: Homo sapiens similar to ribosomal proteinL10a (LOC401863), mRNA [XR_019597] AK098605 AK098605 Homo sapiens cDNAFLJ25739 fis, clone TST05834. [AK098605] A_24_P127442 A_24_P127442Unknown NM_022736 MFSD1 Homo sapiens major facilitator superfamilydomain containing 1 (MFSD1), mRNA [NM_022736] NM_203495 COMMD6 Homosapiens COMM domain containing 6 (COMMD6), transcript variant 2, mRNA[NM_203495] NM_153236 GIMAP7 Homo sapiens GTPase, IMAP family member 7(GIMAP7), mRNA [NM_153236] XM_935576 LOC641827 PREDICTED: Homo sapienssimilar to eukaryotic translation elongation factor 1 beta 2(LOC641827), mRNA [XM_935576] NM_004713 SDCCAG1 Homo sapiensserologically defined colon cancer antigen 1 (SDCCAG1), mRNA [NM_004713]NR_001577 NME2P1 Homo sapiens non-metastatic cells 2, protein (NM23B)expressed in, pseudogene 1 (NME2P1) on chromosome 12 [NR_001577]NM_000569 FCGR3A Homo sapiens Fc fragment of IgG, low affinity IIIa,receptor (CD16a) (FCGR3A), mRNA [NM_000569] NM_007308 SNCA Homo sapienssynuclein, alpha (non A4 component of amyloid precursor) (SNCA),transcript variant NACP112, mRNA [NM_007308] XR_015767 LOC731224PREDICTED: Homo sapiens similar to 60S ribosomal protein L9 (LOC731224),mRNA [XR_015767] NM_007104 RPL10A Homo sapiens ribosomal protein L10a(RPL10A), mRNA [NM_007104] NM_016039 C14orf166 Homo sapiens chromosome14 open reading frame 166 (C14orf166), mRNA [NM_016039] NM_003295 TPT1Homo sapiens tumor protein, translationally-controlled 1 (TPT1), mRNA[NM_003295] AK124741 AK124741 Homo sapiens cDNA FLJ42751 fis, cloneBRAWH3000491, moderately similar to 40S ribosomal protein S12.[AK124741] NM_005617 RPS14 Homo sapiens ribosomal protein S14 (RPS14),transcript variant 3, mRNA [NM_005617] NM_000986 RPL24 Homo sapiensribosomal protein L24 (RPL24), mRNA [NM_000986] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] XM_001125895LOC730452 PREDICTED: Homo sapiens similar to 60S ribosomal protein L7(LOC730452), mRNA [XM_001125895] NM_001011 RPS7 Homo sapiens ribosomalprotein S7 (RPS7), mRNA [NM_001011] XR_018994 LOC391181 PREDICTED: Homosapiens similar to 60S ribosomal protein L6 (TAX-responsive enhancerelement-binding protein 107) (TAXREB107) (Neoplasm-related protein C140)(LOC391181), mRNA [XR_018994] A_24_P332441 A_24_P332441 UnknownNM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcriptvariant 1, mRNA [NM_000967] NM_002414 CD99 Homo sapiens CD99 molecule(CD99), mRNA [NM_002414] NM_006013 RPL10 Homo sapiens ribosomal proteinL10 (RPL10), mRNA [NM_006013] NM_000982 RPL21 Homo sapiens ribosomalprotein L21 (RPL21), mRNA [NM_000982] NM_000969 RPL5 Homo sapiensribosomal protein L5 (RPL5), mRNA [NM_000969] XR_018341 LOC390413PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC390413),mRNA [XR_018341] NM_014369 PTPN18 Homo sapiens protein tyrosinephosphatase, non-receptor type 18 (brain-derived) (PTPN18), mRNA[NM_014369] XR_018054 LOC392878 PREDICTED: Homo sapiens hypotheticalLOC392878 (LOC392878), mRNA [XR_018054] NM_006013 RPL10 Homo sapiensribosomal protein L10 (RPL10), mRNA [NM_006013] A_24_P608790A_24_P608790 Unknown NM_001011 RPS7 Homo sapiens ribosomal protein S7(RPS7), mRNA [NM_001011] ENST00000332696 ENST00000332696 similar to 60Sribosomal protein L23a (LOC644384), mRNA [Source: RefSeq_dna; Acc:XR_017413] [ENST00000332696] NM_006360 PCID1 Homo sapiens PCI domaincontaining 1 (herpesvirus entry mediator) (PCID1), mRNA [NM_006360]A_24_P204474 A_24_P204474 Unknown NM_018943 TUBA8 Homo sapiens tubulin,alpha 8 (TUBA8), mRNA [NM_018943] A_32_P208856 A_32_P208856 UnknownNM_001404 EEF1G Homo sapiens eukaryotic translation elongation factor 1gamma (EEF1G), mRNA [NM_001404] ENST00000313620 LOC342994 PREDICTED:Homo sapiens similar to ribosomal protein L34 (LOC342994), mRNA[XM_938484] A_24_P126902 A_24_P126902 Unknown THC2506377 THC2506377HSU02032 ribosomal protein L23a {Homo sapiens} (exp = −1; wgp = 0; cg =0), partial (92%) [THC2506377] NM_000998 RPL37A Homo sapiens ribosomalprotein L37a (RPL37A), mRNA [NM_000998] AY033611 AY033611 Homo sapiensplacenta immunoregulatory factor PLIF mRNA, complete cds. [AY033611]NM_000454 SOD1 Homo sapiens superoxide dismutase 1, soluble (amyotrophiclateral sclerosis 1 (adult)) (SOD1), mRNA [NM_000454] NM_005340 HINT1Homo sapiens histidine triad nucleotide binding protein 1 (HINT1), mRNA[NM_005340] NM_006013 RPL10 Homo sapiens ribosomal protein L10 (RPL10),mRNA [NM_006013] NM_080746 RPL10L Homo sapiens ribosomal proteinL10-like (RPL10L), mRNA [NM_080746] ENST00000361390 ND1 NADH-ubiquinoneoxidoreductase chain 1 (EC 1.6.5.3) (NADH dehydrogenase subunit 1).[Source: Uniprot/SWISSPROT; Acc: P03886] [ENST00000361390] A_24_P50489A_24_P50489 Unknown NM_005437 NCOA4 Homo sapiens nuclear receptorcoactivator 4 (NCOA4), mRNA [NM_005437] NM_175839 SMOX Homo sapiensspermine oxidase (SMOX), transcript variant 1, mRNA [NM_175839]XR_019242 LOC402149 PREDICTED: Homo sapiens similar to ribosomal proteinL28 (LOC402149), mRNA [XR_019242] NM_002568 PABPC1 Homo sapiens poly(A)binding protein, cytoplasmic 1 (PABPC1), mRNA [NM_002568] NP1252191NP1252191 GB|AACC02000041.1|EAL24419.1 similar to 60S ribosomal proteinL32 [Homo sapiens] [NP1252191] NM_000997 RPL37 Homo sapiens ribosomalprotein L37 (RPL37), mRNA [NM_000997] NM_000986 RPL24 Homo sapiensribosomal protein L24 (RPL24), mRNA [NM_000986] NM_003752 EIF3S8 Homosapiens eukaryotic translation initiation factor 3, subunit 8, 110 kDa(EIF3S8), transcript variant 1, mRNA [NM_003752] NM_015933 CCDC72 Homosapiens coiled-coil domain containing 72 (CCDC72), mRNA [NM_015933]XR_019052 LOC391738 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L29 (Cell surface heparin-binding protein HIP) (LOC391738), mRNA[XR_019052] NM_004548 NDUFB10 Homo sapiens NADH dehydrogenase(ubiquinone) 1 beta subcomplex, 10, 22 kDa (NDUFB10), mRNA [NM_004548]XR_018303 LOC648378 PREDICTED: Homo sapiens similar to ribosomal proteinS14 (LOC648378), mRNA [XR_018303] XM_928025 LOC644937 PREDICTED: Homosapiens similar to 60S ribosomal protein L10 (QM protein) (Tumorsuppressor QM) (Laminin receptor homolog) (LOC644937), mRNA [XM_928025]NM_032310 C9orf89 Homo sapiens chromosome 9 open reading frame 89(C9orf89), mRNA [NM_032310] AL137354 AL137354 Homo sapiens mRNA; cDNADKFZp434A0326 (from clone DKFZp434A0326). [AL137354] NM_002032 FTH1 Homosapiens ferritin, heavy polypeptide 1 (FTH1), mRNA [NM_002032] NM_001101ACTB Homo sapiens actin, beta (ACTB), mRNA [NM_001101] XM_930195hCG_18290 PREDICTED: Homo sapiens similar to 60S ribosomal protein L32(LOC644907), mRNA [XM_930195] BC089454 BC089454 Homo sapiens cDNA cloneMGC: 105145 IMAGE: 30563285, complete cds. [BC089454] NM_001865 COX7A2Homo sapiens cytochrome c oxidase subunit VIIa polypeptide 2 (liver)(COX7A2), mRNA [NM_001865] NM_005319 HIST1H1C Homo sapiens histonecluster 1, H1c (HIST1H1C), mRNA [NM_005319] NM_001080544 LOC653314 Homosapiens similar to ribosomal protein L19 (LOC653314), mRNA[NM_001080544] NM_021009 UBC Homo sapiens ubiquitin C (UBC), mRNA[NM_021009] ENST00000333351 ENST00000333351 PREDICTED: Homo sapienshypothetical LOC391504 (LOC391504), mRNA [XR_018627] A_24_P843921A_24_P843921 Unknown NM_198253 TERT Homo sapiens telomerase reversetranscriptase (TERT), transcript variant 1, mRNA [NM_198253] NM_198253TERT Homo sapiens telomerase reverse transcriptase (TERT), transcriptvariant 1, mRNA [NM_198253] NM_130766 SKIP Homo sapiens skeletal muscleand kidney enriched inositol phosphatase (SKIP), transcript variant 2,mRNA [NM_130766] NM_002617 PEX10 Homo sapiens peroxisome biogenesisfactor 10 (PEX10), transcript variant 2, mRNA [NM_002617] NM_173833SCARA5 Homo sapiens scavenger receptor class A, member 5 (putative)(SCARA5), mRNA [NM_173833] NM_152339 SPATA2L Homo sapiensspermatogenesis associated 2-like (SPATA2L), mRNA [NM_152339] NM_007185TNRC4 Homo sapiens trinucleotide repeat containing 4 (TNRC4), mRNA[NM_007185] NM_182688 UBE2G2 Homo sapiens ubiquitin-conjugating enzymeE2G 2 (UBC7 homolog, yeast) (UBE2G2), transcript variant 2, mRNA[NM_182688] A_24_P636974 A_24_P636974 Unknown NM_015901 NUDT13 Homosapiens nudix (nucleoside diphosphate linked moiety X)-type motif 13(NUDT13), mRNA [NM_015901] NM_002141 HOXA4 Homo sapiens homeobox A4(HOXA4), mRNA [NM_002141] NM_001837 CCR3 Homo sapiens chemokine (C-Cmotif) receptor 3 (CCR3), transcript variant 1, mRNA [NM_001837]NM_201999 ELF2 Homo sapiens E74-like factor 2 (ets domain transcriptionfactor) (ELF2), transcript variant 1, mRNA [NM_201999] AK000420 AK000420Homo sapiens cDNA FLJ20413 fis, clone KAT02170. [AK000420] NM_024812BAALC Homo sapiens brain and acute leukemia, cytoplasmic (BAALC),transcript variant 1, mRNA [NM_024812] A_23_P129405 A_23_P129405 UnknownNM_000539 RHO Homo sapiens rhodopsin (opsin 2, rod pigment) (retinitispigmentosa 4, autosomal dominant) (RHO), mRNA [NM_000539] NM_198253 TERTHomo sapiens telomerase reverse transcriptase (TERT), transcript variant1, mRNA [NM_198253] XM_372498 LOC390427 PREDICTED: Homo sapiens similarto TBP-associated factor 15 isoform 1 (LOC390427), mRNA [XM_372498]THC2726959 THC2726959 Unknown THC2760960 THC2760960 Unknown THC2718728THC2718728 Unknown NM_173728 ARHGEF15 Homo sapiens Rho guaninenucleotide exchange factor (GEF) 15 (ARHGEF15), mRNA [NM_173728]NM_198253 TERT Homo sapiens telomerase reverse transcriptase (TERT),transcript variant 1, mRNA [NM_198253] THC2667666 THC2667666 UnknownA_24_P636834 A_24_P636834 Unknown NM_173078 SLITRK4 Homo sapiens SLITand NTRK-like family, member 4 (SLITRK4), mRNA [NM_173078] NM_002307LGALS7 Homo sapiens lectin, galactoside-binding, soluble, 7 (galectin 7)(LGALS7), mRNA [NM_002307] ENST00000248668 LRFN1 Leucine-rich repeat andfibronectin type III domain-containing protein 1 (Fragment). [Source:Uniprot/SPTREMBL; Acc: Q9P244] [ENST00000248668] THC2532155 THC2532155Q8K2W0_MOUSE (Q8K2W0) Procollagen, type IX, alpha 2, partial (3%)[THC2532155] ENST00000325151 ENST00000325151 Small inducible cytokineA27 precursor (CCL27) (CC chemokine ILC) (IL-11 R-alpha-locus chemokine)(Skinkine) (ESkine) (Cutaneous T-cell-attracting chemokine) (CTACK).[Source: Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_006266RALGDS Homo sapiens ral guanine nucleotide dissociation stimulator(RALGDS), transcript variant 1, mRNA [NM_006266] NM_198253 TERT Homosapiens telomerase reverse transcriptase (TERT), transcript variant 1,mRNA [NM_198253] NM_004703 RABEP1 Homo sapiens rabaptin, RAB GTPasebinding effector protein 1 (RABEP1), transcript variant 1, mRNA[NM_004703] NM_001138 AGRP Homo sapiens agouti related protein homolog(mouse) (AGRP), transcript variant 1, mRNA [NM_001138] XM_001133403LOC732417 PREDICTED: Homo sapiens hypothetical protein LOC732417(LOC732417), mRNA [XM_001133403] NM_207377 UNQ9438 Homo sapiens TIMM9(UNQ9438), mRNA [NM_207377] NM_002307 LGALS7 Homo sapiens lectin,galactoside-binding, soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307]BI262095 BI262095 BI262095 602953519T1 NIH_MGC_99 Homo sapiens cDNAclone IMAGE: 5087621 3′, mRNA sequence [BI262095] NM_145234 CHRDL1 Homosapiens chordin-like 1 (CHRDL1), mRNA [NM_145234] NM_016219 MAN1B1 Homosapiens mannosidase, alpha, class 1B, member 1 (MAN1B1), mRNA[NM_016219] NM_018670 MESP1 Homo sapiens mesoderm posterior 1 homolog(mouse) (MESP1), mRNA [NM_018670] NM_004819 SYMPK Homo sapiens symplekin(SYMPK), mRNA [NM_004819] BU561469 BU561469 AGENCOURT_10278709NIH_MGC_82 Homo sapiens cDNA clone IMAGE: 6592525 5′, mRNA sequence[BU561469] NM_015088 TNRC6B Homo sapiens trinucleotide repeat containing6B (TNRC6B), transcript variant 1, mRNA [NM_015088] ENST00000299974ENST00000299974 ATP/GTP binding protein-like 1 [Source: RefSeq_peptide;Acc: NP_689549] [ENST00000299974] NM_175734 C17orf74 Homo sapienschromosome 17 open reading frame 74 (C17orf74), mRNA [NM_175734]NM_152384 BBS5 Homo sapiens Bardet-Biedl syndrome 5 (BBS5), mRNA[NM_152384] J03651 J03651 Human DF3 breast carcinoma-associated antigenmRNA, partial cds. [J03651] A_23_P46070 A_23_P46070 Unknown NM_004750CRLF1 Homo sapiens cytokine receptor-like factor 1 (CRLF1), mRNA[NM_004750] NM_003508 FZD9 Homo sapiens frizzled homolog 9 (Drosophila)(FZD9), mRNA [NM_003508] AL566332 AL566332 AL566332 AL566332 Homosapiens FETAL BRAIN Homo sapiens cDNA clone CS0DF015YB18 3-PRIME, mRNAsequence [AL566332] A_24_P144625 A_24_P144625 Unknown AA418814 AA418814AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3′, mRNA sequence [AA418814] A_32_P186382 A_32_P186382 UnknownNM_203374 ZNF784 Homo sapiens zinc finger protein 784 (ZNF784), mRNA[NM_203374] ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI)(Serpin B1) (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI).[Source: Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183FOXD3 Homo sapiens forkhead box D3 (FOXD3), mRNA [NM_012183]ENST00000328043 ENST00000328043 LRP11 protein (Fragment). [Source:Uniprot/SPTREMBL; Acc: Q96AT3] [ENST00000328043] NM_019105 TNXB Homosapiens tenascin XB (TNXB), transcript variant XB, mRNA [NM_019105]ENST00000325371 ENST00000325371 Homo sapiens cDNA clone IMAGE: 4819956.[BC018035] THC2504037 THC2504037 ALU1_HUMAN (P39188) Alu subfamily Jsequence contamination warning entry, partial (7%) [THC2504037]NM_174903 RNF151 Homo sapiens ring finger protein 151 (RNF151), mRNA[NM_174903] NM_022555 HLA-DRB3 Homo sapiens major histocompatibilitycomplex, class II, DR beta 3 (HLA-DRB3), mRNA [NM_022555]ENST00000360514 ENST00000360514 Homo sapiens hypothetical LOC339483,mRNA (cDNA clone MGC: 52427 IMAGE: 4872239), complete cds. [BC041632]THC2694242 THC2694242 Unknown NM_138763 BAX Homo sapiens BCL2-associatedX protein (BAX), transcript variant delta, mRNA [NM_138763] NM_002691POLD1 Homo sapiens polymerase (DNA directed), delta 1, catalytic subunit125 kDa (POLD1), mRNA [NM_002691] ENST00000331849 FLJ20581 CDNA FLJ20581fis, clone REC00491. [Source: Uniprot/SPTREMBL; Acc: Q9NWV3][ENST00000331849] XR_018717 FDPSL4 PREDICTED: Homo sapiens similar tofarnesyl diphosphate synthase (LOC390580), mRNA [XR_018717] NM_152418WDR21C Homo sapiens WD repeat domain 21C (WDR21C), mRNA [NM_152418]NM_203304 RKHD1 Homo sapiens ring finger and KH domain containing 1(RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiens leucine-richrepeat-containing G protein-coupled receptor 4 (LGR4), mRNA [NM_018490]NM_001611 ACP5 Homo sapiens acid phosphatase 5, tartrate resistant(ACP5), mRNA [NM_001611] NM_174976 ZDHHC22 Homo sapiens zinc finger,DHHC-type containing 22 (ZDHHC22), mRNA [NM_174976] CV575560 CV575560oe37f10.y1 Human keratoconus cornea, unamplified, (od [CV575560]

TABLE 14 Gene list generated at the inclusion criteria of p ≦ 0.05 andthe log-median-ratio being at least “0.585” or above. GenBank AccessionGene Name Description NR_001543 TTTY14 Homo sapiens testis-specifictranscript, Y-linked 14 (TTTY14) on chromosome Y [NR_001543] NM_004864GDF15 Homo sapiens growth differentiation factor 15 (GDF15), mRNA[NM_004864] BF822111 BF822111 BF822111 CM3-RT0011-051200-531-f10 RT0011Homo sapiens cDNA, mRNA sequence [BF822111] A_23_P329062 A_23_P329062Unknown NM_019064 SDK2 Homo sapiens sidekick homolog 2 (chicken) (SDK2),mRNA [NM_019064] NM_145173 DIRAS1 Homo sapiens DIRAS family, GTP-bindingRAS-like 1 (DIRAS1), mRNA [NM_145173] NM_016434 RTEL1 Homo sapiensregulator of telomere elongation helicase 1 (RTEL1), transcript variant1, mRNA [NM_016434] NM_013246 CLCF1 Homo sapiens cardiotrophin-likecytokine factor 1 (CLCF1), mRNA [NM_013246] THC2726026 THC2726026Q3X600_9ACTN (Q3X600) Adenine deaminase, partial (4%) [THC2726026]NM_178013 PRIMA1 Homo sapiens proline rich membrane anchor 1 (PRIMA1),mRNA [NM_178013] AK091355 LOC284926 Homo sapiens cDNA FLJ34036 fis,clone FCBBF2005069. [AK091355] A_24_P853410 A_24_P853410 UnknownA_24_P780709 A_24_P780709 Unknown NM_178428 LCE2A Homo sapiens latecornified envelope 2A (LCE2A), mRNA [NM_178428] NM_006864 LILRB3 Homosapiens leukocyte immunoglobulin-like receptor, subfamily B (with TM andITIM domains), member 3 (LILRB3), transcript variant 2, mRNA [NM_006864]AK057167 AK057167 Homo sapiens cDNA FLJ32605 fis, clone STOMA1000175.[AK057167] NM_003748 ALDH4A1 Homo sapiens aldehyde dehydrogenase 4family, member A1 (ALDH4A1), nuclear gene encoding mitochondrialprotein, transcript variant P5CDhL, mRNA [NM_003748] THC2679528THC2679528 Unknown AF355801 CYP3A5 Homo sapiens CYP3A5 mRNA, alleleCYP3A5*3, exon 4B and partial cds, alternatively spliced. [AF355801]NM_001005862 ERBB2 Homo sapiens v-erb-b2 erythroblastic leukemia viraloncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)(ERBB2), transcript variant 2, mRNA [NM_001005862] A_24_P471099A_24_P471099 Unknown NM_006283 TACC1 Homo sapiens transforming, acidiccoiled-coil containing protein 1 (TACC1), mRNA [NM_006283] NM_025004CCDC15 Homo sapiens coiled-coil domain containing 15 (CCDC15), mRNA[NM_025004] NM_002124 HLA-DRB1 Homo sapiens major histocompatibilitycomplex, class II, DR beta 1 (HLA-DRB1), mRNA [NM_002124] NM_012435 SHC2Homo sapiens SHC (Src homology 2 domain containing) transforming protein2 (SHC2), mRNA [NM_012435] AF116688 AF116688 Homo sapiens PRO2133 mRNA,complete cds. [AF116688] NM_021959 PPP1R11 Homo sapiens proteinphosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA[NM_021959] A_24_P786912 A_24_P786912 Unknown NM_030914 URM1 Homosapiens ubiquitin related modifier 1 homolog (S. cerevisiae) (URM1),mRNA [NM_030914] NM_014408 TRAPPC3 Homo sapiens trafficking proteinparticle complex 3 (TRAPPC3), mRNA [NM_014408] NM_003142 SSB Homosapiens Sjogren syndrome antigen B (autoantigen La) (SSB), mRNA[NM_003142] NM_031918 KLF16 Homo sapiens Kruppel-like factor 16 (KLF16),mRNA [NM_031918] THC2700213 THC2700213 Q5VZP2_HUMAN (Q5VZP2) HERV-HLTR-associating 3, partial (21%) [THC2700213] THC2553131 THC2553131Q59FA2_HUMAN (Q59FA2) Splicing factor, arginine/serine-rich 1 (Splicingfactor 2, alternate splicing factor) variant (Fragment), partial (18%)[THC2553131] THC2729352 THC2729352 Unknown NM_001492 GDF1 Homo sapiensgrowth differentiation factor 1 (GDF1), mRNA [NM_001492] NM_006907 PYCR1Homo sapiens pyrroline-5-carboxylate reductase 1 (PYCR1), transcriptvariant 1, mRNA [NM_006907] NM_006653 FRS3 Homo sapiens fibroblastgrowth factor receptor substrate 3 (FRS3), mRNA [NM_006653] AL096727AL096727 Homo sapiens mRNA; cDNA DKFZp434B104 (from clone DKFZp434B104).[AL096727] NM_022139 GFRA4 Homo sapiens GDNF family receptor alpha 4(GFRA4), transcript variant 1, mRNA [NM_022139] A_32_P161913A_32_P161913 Unknown AK074447 FLJ23867 Homo sapiens cDNA FLJ23867 fis,clone LNG09729. [AK074447] NM_015271 TRIM2 Homo sapiens tripartitemotif-containing 2 (TRIM2), mRNA [NM_015271] A_32_P101195 A_32_P101195Unknown U19144 GAGE3 Human GAGE-3 protein mRNA, complete cds. [U19144]THC2503819 THC2503819 BC010854 amyloid beta A4 precursorprotein-binding, family B, member 1, isoform delta E9 {Homo sapiens}(exp = −1; wgp = 0; cg = 0), partial (22%) [THC2503819] THC2618720THC2618720 Unknown NM_194248 OTOF Homo sapiens otoferlin (OTOF),transcript variant 1, mRNA [NM_194248] NM_014580 SLC2A8 Homo sapienssolute carrier family 2, (facilitated glucose transporter) member 8(SLC2A8), mRNA [NM_014580] NM_080606 BHLHB4 Homo sapiens basichelix-loop-helix domain containing, class B, 4 (BHLHB4), mRNA[NM_080606] NM_032478 MRPL38 Homo sapiens mitochondrial ribosomalprotein L38 (MRPL38), nuclear gene encoding mitochondrial protein, mRNA[NM_032478] A_32_P90178 A_32_P90178 Unknown N75427 N75427 za82f07.s1Soares_fetal_lung_NbHL19W Homo sapiens cDNA clone IMAGE: 299077 3′similar to gb: X69654 40S RIBOSOMAL PROTEIN S26 (HUMAN);, mRNA sequence[N75427] A_32_P144634 A_32_P144634 Unknown NM_015481 ZNF385 Homo sapienszinc finger protein 385 (ZNF385), mRNA [NM_015481] NM_001988 EVPL Homosapiens envoplakin (EVPL), mRNA [NM_001988] AK097411 FLJ40092 Homosapiens cDNA FLJ40092 fis, clone TESTI2003756. [AK097411] AA436686AA436686 AA436686 zv59a12.s1 Soares_testis_NHT Homo sapiens cDNA cloneIMAGE: 757918 3′ similar to contains Alu repetitive element;, mRNAsequence [AA436686] A_32_P227496 A_32_P227496 Unknown BC024303 FLJ35390Homo sapiens hypothetical protein FLJ35390, mRNA (cDNA clone IMAGE:4328569), with apparent retained intron. [BC024303] NM_003833 MATN4 Homosapiens matrilin 4 (MATN4), transcript variant 1, mRNA [NM_003833]XM_926898 LOC643594 PREDICTED: Homo sapiens similar to CG13731-PA(LOC643594), mRNA [XM_926898] BX111592 BX111592 BX111592Soares_testis_NHT Homo sapiens cDNA clone IMAGp998D162621, mRNA sequence[BX111592] NM_080825 C20orf144 Homo sapiens chromosome 20 open readingframe 144 (C20orf144), mRNA [NM_080825] AF161342 AF161342 Homo sapiensHSPC079 mRNA, partial cds. [AF161342] NM_003614 GALR3 Homo sapiensgalanin receptor 3 (GALR3), mRNA [NM_003614] NM_001005862 ERBB2 Homosapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 2,neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcriptvariant 2, mRNA [NM_001005862] A_24_P461664 A_24_P461664 UnknownNM_004609 TCF15 Homo sapiens transcription factor 15 (basichelix-loop-helix) (TCF15), mRNA [NM_004609] X56681 JUND Human junD mRNA.[X56681] ENST00000330598 ENST00000330598 Homo sapiens HSPC088 mRNA,partial cds. [AF161351] NM_006270 RRAS Homo sapiens related RAS viral(r-ras) oncogene homolog (RRAS), mRNA [NM_006270] NM_030974 SHARPIN Homosapiens SHANK-associated RH domain interactor (SHARPIN), mRNA[NM_030974] THC2744561 THC2744561 Unknown NM_178430 LCE2D Homo sapienslate cornified envelope 2D (LCE2D), mRNA [NM_178430] THC2529614THC2529614 Q3VHI9_9SPHN (Q3VHI9) Manganese and iron superoxide dismutaseprecursor, partial (8%) [THC2529614] AK096674 AK096674 Homo sapiens cDNAFLJ39355 fis, clone PEBLM2003426. [AK096674] ENST00000356572ENST00000356572 FAM39B protein. [Source: Uniprot/SPTREMBL; Acc: Q6GMS0][ENST00000356572] A_23_P105732 A_23_P105732 Unknown NM_032789 PARP10Homo sapiens poly (ADP-ribose) polymerase family, member 10 (PARP10),mRNA [NM_032789] NM_005634 SOX3 Homo sapiens SRY (sex determining regionY)-box 3 (SOX3), mRNA [NM_005634] BC035978 ATP6V1B1 Homo sapiens ATPase,H+ transporting, lysosomal 56/58 kDa, V1 subunit B1 (Renal tubularacidosis with deafness), mRNA (cDNA clone MGC: 32642 IMAGE: 4594171),complete cds. [BC035978] A_32_P11425 A_32_P11425 Unknown BX094246BX094246 BX094246 Soares_testis_NHT Homo sapiens cDNA cloneIMAGp998N201862, mRNA sequence [BX094246] THC2646425 THC2646425 UnknownBC000408 ACAT2 Homo sapiens acetyl-Coenzyme A acetyltransferase 2(acetoacetyl Coenzyme A thiolase), mRNA (cDNA clone MGC: 8573 IMAGE:2823036), complete cds. [BC000408] AK055960 AK055960 Homo sapiens cDNAFLJ31398 fis, clone NT2NE1000175. [AK055960] AF116619 AF116619 Homosapiens PRO1051 mRNA, complete cds. [AF116619] THC2641678 THC2641678Unknown NM_005781 TNK2 Homo sapiens tyrosine kinase, non-receptor, 2(TNK2), transcript variant 1, mRNA [NM_005781] A_32_P220567 A_32_P220567Unknown AF095737 SARDH Homo sapiens SARDH mRNA, alternatively spliced,complete cds. [AF095737] NM_004364 CEBPA Homo sapiens CCAAT/enhancerbinding protein (C/EBP), alpha (CEBPA), mRNA [NM_004364] A_32_P138939A_32_P138939 Unknown XM_209227 LOC653464 PREDICTED: Homo sapiens similarto SLIT-ROBO Rho GTPase- activating protein 2 (srGAP2) (Formin-bindingprotein 2) (LOC653464), mRNA [XM_209227] NM_033506 FBXO24 Homo sapiensF-box protein 24 (FBXO24), transcript variant 1, mRNA [NM_033506]THC2688313 THC2688313 Q6NUK7_HUMAN (Q6NUK7) LYN protein (Fragment),partial (9%) [THC2688313] CN304251 CN304251 17000532640995 GRN_ES Homosapiens cDNA 5′, mRNA sequence [CN304251] A_32_P15706 A_32_P15706Unknown ENST00000332863 ENST00000332863 Q3RT01_RALME (Q3RT01) 2OG-Fe(II)oxygenase superfamily, partial (6%) [THC2740296] AK027211 AK027211 Homosapiens cDNA: FLJ23558 fis, clone LNG09703. [AK027211] NM_001004321FLJ45445 Homo sapiens FLJ45445 protein (FLJ45445), mRNA [NM_001004321]A_24_P533990 A_24_P533990 Unknown AF010315 TP53I11 Homo sapiens Pig11(PIG11) mRNA, complete cds. [AF010315] NM_022036 GPRC5C Homo sapiens Gprotein-coupled receptor, family C, group 5, member C (GPRC5C),transcript variant 1, mRNA [NM_022036] NM_001005862 ERBB2 Homo sapiensv-erb-b2 erythroblastic leukemia viral oncogene homolog 2,neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcriptvariant 2, mRNA [NM_001005862] NM_019067 GNL3L Homo sapiens guaninenucleotide binding protein-like 3 (nucleolar)-like (GNL3L), mRNA[NM_019067] NM_020182 TMEPAI Homo sapiens transmembrane, prostateandrogen induced RNA (TMEPAI), transcript variant 1, mRNA [NM_020182]THC2654007 THC2654007 Unknown NM_006522 WNT6 Homo sapiens wingless-typeMMTV integration site family, member 6 (WNT6), mRNA [NM_006522] BC037255LOC389634 Homo sapiens hypothetical LOC389634, mRNA (cDNA clone IMAGE:4157715). [BC037255] THC2693842 THC2693842 Unknown A_32_P112100A_32_P112100 Unknown NM_005772 RCL1 Homo sapiens RNA terminal phosphatecyclase-like 1 (RCL1), mRNA [NM_005772] THC2557053 THC2557053Q95HC0_HUMAN (Q95HC0) HLA-F protein (Fragment), partial (15%)[THC2557053] NM_024407 NDUFS7 Homo sapiens NADH dehydrogenase(ubiquinone) Fe—S protein 7, 20 kDa (NADH-coenzyme Q reductase)(NDUFS7), mRNA [NM_024407] AI751518 AI751518 AI751518 cn10d09.y1 NormalHuman Trabecular Bone Cells Homo sapiens cDNA clone NHTBC_cn10d09random, mRNA sequence [AI751518] NM_152636 METT5D1 Homo sapiensmethyltransferase 5 domain containing 1 (METT5D1), mRNA [NM_152636]THC2694215 THC2694215 Q3W9Q7_9ACTO (Q3W9Q7) Pyridoxamine 5′-phosphateoxidase, partial (3%) [THC2694215] A_24_P350252 A_24_P350252 UnknownNM_006885 ATBF1 Homo sapiens AT-binding transcription factor 1 (ATBF1),mRNA [NM_006885] NM_020654 SENP7 Homo sapiens SUMO1/sentrin specificpeptidase 7 (SENP7), transcript variant 1, mRNA [NM_020654] NM_016148SHANK1 Homo sapiens SH3 and multiple ankyrin repeat domains 1 (SHANK1),mRNA [NM_016148] NP111770 NP111770 GB|M18679.1|AAA67373.1 putative[NP111770] NM_018991 DKFZP434A0131 Homo sapiens DKFZp434A0131 protein(DKFZP434A0131), transcript variant 1, mRNA [NM_018991] NM_000761 CYP1A2Homo sapiens cytochrome P450, family 1, subfamily A, polypeptide 2(CYP1A2), mRNA [NM_000761] ENST00000355748 ENST00000355748 Endogenousretrovirus H D1 leader region/integrase-derived ORF1, ORF2, and putativeenvelope protein (Endogenous retrovirus H protease/integrase-derivedORF1, ORF2, and putative envelope protein). [Source: Uniprot/SPTREMBL;Acc: O00627] [ENST00000355748] NM_145316 C6orf128 Homo sapienschromosome 6 open reading frame 128 (C6orf128), mRNA [NM_145316]NM_022978 SERF1B Homo sapiens small EDRK-rich factor 1B (centromeric)(SERF1B), mRNA [NM_022978] NM_021637 TMEM35 Homo sapiens transmembraneprotein 35 (TMEM35), mRNA [NM_021637] XM_372331 NKX1-2 PREDICTED: Homosapiens NK1 transcription factor related, locus 2 (Drosophila) (NKX1-2),mRNA [XM_372331] NM_005581 BCAM Homo sapiens basal cell adhesionmolecule (Lutheran blood group) (BCAM), transcript variant 1, mRNA[NM_005581] AF119889 AF119889 Homo sapiens PRO2667 mRNA, complete cds.[AF119889] NM_018231 FLJ10815 Homo sapiens amino acid transporter(FLJ10815), mRNA [NM_018231] NM_032792 ZBTB45 Homo sapiens zinc fingerand BTB domain containing 45 (ZBTB45), mRNA [NM_032792] BC047032BC047032 Homo sapiens, clone IMAGE: 3894105, mRNA. [BC047032]ENST00000302932 ENST00000302932 Uncharacterized protein C20orf181(Fragment). [Source: Uniprot/SPTREMBL; Acc: Q92884] [ENST00000302932]BC040051 BC040051 Homo sapiens, clone IMAGE: 6018828, mRNA. [BC040051]NM_139025 ADAMTS13 Homo sapiens ADAM metallopeptidase withthrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 1, mRNA[NM_139025] NM_152764 C16orf73 Homo sapiens chromosome 16 open readingframe 73 (C16orf73), mRNA [NM_152764] NM_015444 TMEM158 Homo sapienstransmembrane protein 158 (TMEM158), mRNA [NM_015444] NM_021170 HES4Homo sapiens hairy and enhancer of split 4 (Drosophila) (HES4), mRNA[NM_021170] ENST00000380295 ENST00000380295 Homo sapiens cDNA cloneIMAGE: 4794059, partial cds. [BC022562] NM_184041 ALDOA Homo sapiensaldolase A, fructose-bisphosphate (ALDOA), transcript variant 2, mRNA[NM_184041] NM_178354 LCE1F Homo sapiens late cornified envelope 1F(LCE1F), mRNA [NM_178354] NM_020764 CASKIN1 Homo sapiens CASKinteracting protein 1 (CASKIN1), mRNA [NM_020764] NM_000427 LOR Homosapiens loricrin (LOR), mRNA [NM_000427] NM_031213 FAM108A1 Homo sapiensfamily with sequence similarity 108, member A1 (FAM108A1), mRNA[NM_031213] NM_006778 TRIM10 Homo sapiens tripartite motif-containing 10(TRIM10), transcript variant 1, mRNA [NM_006778] ENST00000302932ENST00000302932 Uncharacterized protein C20orf181 (Fragment). [Source:Uniprot/SPTREMBL; Acc: Q92884] [ENST00000302932] THC2707284 THC2707284Q214U3_RHOPA (Q214U3) Penicillin-binding protein 1C precursor, partial(3%) [THC2707284] XR_015423 LOC731262 PREDICTED: Homo sapienshypothetical protein LOC731262 (LOC731262), mRNA [XR_015423] M14087M14087 Human HL14 gene encoding beta-galactoside-binding lectin, 3′ end,clone 2. [M14087] A_32_P138933 A_32_P138933 Unknown THC2728513THC2728513 Q26195_PLAVI (Q26195) Pva1 protein, partial (20%)[THC2728513] NM_001080414 KIAA1509 Homo sapiens KIAA1509 (KIAA1509),mRNA [NM_001080414] X74861 HPX-2 H. sapiens HPX-2 mRNA. [X74861]NM_020857 VPS18 Homo sapiens vacuolar protein sorting 18 homolog (S.cerevisiae) (VPS18), mRNA [NM_020857] NM_001395 DUSP9 Homo sapiens dualspecificity phosphatase 9 (DUSP9), mRNA [NM_001395] NM_024742 ARMC5 Homosapiens armadillo repeat containing 5 (ARMC5), mRNA [NM_024742] BC063531SIN3B Homo sapiens SIN3 homolog B, transcription regulator (yeast), mRNA(cDNA clone IMAGE: 4417458), complete cds. [BC063531] NM_000501 ELN Homosapiens elastin (supravalvular aortic stenosis, Williams- Beurensyndrome) (ELN), transcript variant 1, mRNA [NM_000501] NM_020644 TMEM9BHomo sapiens TMEM9 domain family, member B (TMEM9B), mRNA [NM_020644]THC2718728 THC2718728 Unknown NM_032391 PRAC Homo sapiens small nuclearprotein PRAC (PRAC), mRNA [NM_032391] NM_033184 KRTAP2-4 Homo sapienskeratin associated protein 2-4 (KRTAP2-4), mRNA [NM_033184] AK124097AK124097 Homo sapiens cDNA FLJ42103 fis, clone TESOP2007041. [AK124097]NM_014417 BBC3 Homo sapiens BCL2 binding component 3 (BBC3), mRNA[NM_014417] AA151106 AA151106 z148e07.s1 Soares_pregnant_uterus_NbHPUHomo sapiens cDNA clone IMAGE: 505188 3′, mRNA sequence [AA151106]A_24_P417922 A_24_P417922 Unknown THC2666258 THC2666258 P13985_HUMAN(P13985) P25 protein, partial (97%) [THC2666258] A_23_P47220 A_23_P47220Unknown NM_030966 KRTAP1-3 Homo sapiens keratin associated protein 1-3(KRTAP1-3), mRNA [NM_030966] BC017972 BC017972 Homo sapiens, cloneIMAGE: 4693260, mRNA. [BC017972] THC2610890 THC2610890 Q54TC3_DICDI(Q54TC3) FVYE domain-containing protein, partial (3%) [THC2610890]ENST00000248606 PMS2L3 postmeiotic segregation increased 2-like 3isoform 2 [Source: RefSeq_peptide; Acc: NP_001003686] [ENST00000248606]M55405 MUC3A Homo sapiens mucin (MUC-3) mRNA, partial cds. [M55405]NM_032560 SMEK1 Homo sapiens SMEK homolog 1, suppressor of mek1(Dictyostelium) (SMEK1), mRNA [NM_032560] NM_016378 VCX2 Homo sapiensvariable charge, X-linked 2 (VCX2), mRNA [NM_016378] NM_024029 YIPF2Homo sapiens Yip1 domain family, member 2 (YIPF2), mRNA [NM_024029]BC067830 LOC653391 Homo sapiens similar to hypothetical proteinLOC153561, mRNA (cDNA clone MGC: 87375 IMAGE: 5299741), complete cds.[BC067830] CD607715 CD607715 CD607715 56025722H1 FLP Homo sapiens cDNA,mRNA sequence [CD607715] BC080624 BC080624 Homo sapiens cDNA clone MGC:99790 IMAGE: 6304510, complete cds. [BC080624] NM_004386 NCAN Homosapiens neurocan (NCAN), mRNA [NM_004386] A_32_P62137 A_32_P62137Unknown NM_015559 SETBP1 Homo sapiens SET binding protein 1 (SETBP1),mRNA [NM_015559] THC2664581 THC2664581 Q948Y7_VOLCA (Q948Y7) VMP3protein, partial (3%) [THC2664581] AK024440 OXCT2 Homo sapiens mRNA forFLJ00030 protein, partial cds. [AK024440] NM_018645 HES6 Homo sapienshairy and enhancer of split 6 (Drosophila) (HES6), mRNA [NM_018645]XR_018458 LOC440181 PREDICTED: Homo sapiens hypothetical LOC440181(LOC440181), mRNA [XR_018458] NM_001037582 SCD5 Homo sapiensstearoyl-CoA desaturase 5 (SCD5), transcript variant 1, mRNA[NM_001037582] ENST00000379563 VISA Mitochondrial antiviral-signalingprotein (Interferon-beta promoter stimulator protein 1) (IPS-1)(Virus-induced-signaling adapter) (CARD adapter inducinginterferon-beta) (Cardif) (Putative NF- kappa-B-activating protein 031N). . . THC2658813 THC2658813 Unknown NM_017592 IXL Homo sapiensintersex-like (Drosophila) (IXL), mRNA [NM_017592] THC2679528 THC2679528Unknown BU540282 BU540282 AGENCOURT_10326456 NIH_MGC_141 Homo sapienscDNA clone IMAGE: 6571686 5′, mRNA sequence [BU540282] A_24_P392910A_24_P392910 Unknown NM_001080395 AATK Homo sapiens apoptosis-associatedtyrosine kinase (AATK), mRNA [NM_001080395] NM_032536 NTNG2 Homo sapiensnetrin G2 (NTNG2), mRNA [NM_032536] THC2579650 THC2579650 N47124yy53b06.r1 Soares_multiple_sclerosis_2NbHMSP Homo sapiens cDNA cloneIMAGE: 277235 5′, mRNA sequence [N47124] NM_147150 PALM2-AKAP2 Homosapiens PALM2-AKAP2 protein (PALM2-AKAP2), transcript variant 2, mRNA[NM_147150] A_24_P341616 A_24_P341616 Unknown AA484677 AA484677 AA484677ne64a07.s1 NCI_CGAP_Alv1 Homo sapiens cDNA clone IMAGE: 909012, mRNAsequence [AA484677] XR_015273 LOC728371 PREDICTED: Homo sapiens similarto ankyrin repeat domain 20A (LOC728371), mRNA [XR_015273] AB014602SLC24A1 Homo sapiens mRNA for KIAA0702 protein, partial cds. [AB014602]NM_024897 PAQR6 Homo sapiens progestin and adipoQ receptor family memberVI (PAQR6), transcript variant 1, mRNA [NM_024897] NM_181688 KRTAP10-10Homo sapiens keratin associated protein 10-10 (KRTAP10-10), mRNA[NM_181688] THC2654039 THC2654039 ALU2_HUMAN (P39189) Alu subfamily SBsequence contamination warning entry, partial (4%) [THC2654039]NM_033377 CGB1 Homo sapiens chorionic gonadotropin, beta polypeptide 1(CGB1), mRNA [NM_033377] AW467174 AW467174 AW467174 ha35g06.x1NCI_CGAP_Kid12 Homo sapiens cDNA clone IMAGE: 2875738 3′ similar to gb:X60673_rnal GTP:AMP PHOSPHOTRANSFERASE MITOCHONDRIAL (HUMAN);, mRNAsequence [AW467174] NM_001080209 TTMA Homo sapiens two transmembranedomain family member A (TTMA), mRNA [NM_001080209] A_32_P235293A_32_P235293 Unknown NM_004785 SLC9A3R2 Homo sapiens solute carrierfamily 9 (sodium/hydrogen exchanger), member 3 regulator 2 (SLC9A3R2),mRNA [NM_004785] NM_007056 SFRS16 Homo sapiens splicing factor,arginine/serine-rich 16 (SFRS16), mRNA [NM_007056] NM_012148 DUX3 Homosapiens double homeobox, 3 (DUX3), mRNA [NM_012148] NM_001005862 ERBB2Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 2,neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcriptvariant 2, mRNA [NM_001005862] ENST00000340381 ENST00000340381 Novelprotein. [Source: Uniprot/SPTREMBL; Acc: Q5SNT2] [ENST00000340381]AK096255 AK096255 Homo sapiens cDNA FLJ38936 fis, clone NT2NE2015275.[AK096255] A_23_P211603 A_23_P211603 Unknown AK098372 AK098372 Homosapiens cDNA FLJ25506 fis, clone CBR05185. [AK098372] NM_000683 ADRA2CHomo sapiens adrenergic, alpha-2C-, receptor (ADRA2C), mRNA [NM_000683]A_23_P113762 A_23_P113762 Unknown A_23_P119407 A_23_P119407 UnknownAK127569 AK127569 Homo sapiens cDNA FLJ45662 fis, clone CTONG2027150.[AK127569] NM_014460 CSDC2 Homo sapiens cold shock domain containing C2,RNA binding (CSDC2), mRNA [NM_014460] NM_033315 RASL10B Homo sapiensRAS-like, family 10, member B (RASL10B), mRNA [NM_033315] NM_013356SLC16A8 Homo sapiens solute carrier family 16, member 8 (monocarboxylicacid transporter 3) (SLC16A8), mRNA [NM_013356] NM_152219 GJC1 Homosapiens gap junction protein, chi 1, 31.9 kDa (GJC1), mRNA [NM_152219]NM_013452 VCX Homo sapiens variable charge, X-linked (VCX), mRNA[NM_013452] NM_015654 NAT9 Homo sapiens N-acetyltransferase 9 (NAT9),mRNA [NM_015654] NM_004914 RAB36 Homo sapiens RAB36, member RAS oncogenefamily RAB36), mRNA [NM_004914] NM_015335 THRAP2 Homo sapiens thyroidhormone receptor associated protein 2 (THRAP2), mRNA [NM_015335]NM_012147 DUX2 Homo sapiens double homeobox, 2 (DUX2), mRNA [NM_012147]NM_000587 C7 Homo sapiens complement component 7 (C7), mRNA [NM_000587]AK127966 AK127966 Homo sapiens cDNA FLJ46080 fis, clone TESTI2004971.[AK127966] NM_014501 UBE2S Homo sapiens ubiquitin-conjugating enzyme E2S(UBE2S), mRNA [NM_014501] THC2670603 THC2670603 BQ690425AGENCOURT_8176614 NIH_MGC_110 Homo sapiens cDNA clone IMAGE: 6252524 5′,mRNA sequence [BQ690425] NM_001277 CHKA Homo sapiens choline kinasealpha (CHKA), transcript variant 1, mRNA [NM_001277] ENST00000323800ENST00000323800 CDNA FLJ25155 fis, clone CBR07976. [Source:Uniprot/SPTREMBL; Acc: Q96LR6] [ENST00000323800] BQ018742 BQ018742BQ018742 UI-H-DH1-awu-d-06-0-UI.s1 NCI_CGAP_DH1 Homo sapiens cDNA cloneIMAGE: 5823701 3′, mRNA sequence [BQ018742] AK057576 AK057576 Homosapiens cDNA FLJ33014 fis, clone THYMU1000382. [AK057576] THC2737361THC2737361 Q2IMJ3_ANADE (Q2IMJ3) LigA, partial (5%) [THC2737361]XM_209227 LOC653464 PREDICTED: Homo sapiens similar to SLIT-ROBO RhoGTPase- activating protein 2 (srGAP2) (Formin-binding protein 2)(LOC653464), mRNA [XM_209227] THC2755576 THC2755576 ALU1_HUMAN (P39188)Alu subfamily J sequence contamination warning entry, partial (13%)[THC2755576] NM_020061 OPN1LW Homo sapiens opsin 1 (cone pigments),long-wave-sensitive (color blindness, protan) (OPN1LW), mRNA [NM_020061]AK128592 DNHD2 Homo sapiens cDNA FLJ46751 fis, clone TRACH3022960,weakly similar to Dynein beta chain, ciliary. [AK128592] NM_006889 CD86Homo sapiens CD86 molecule (CD86), transcript variant 2, mRNA[NM_006889] THC2528011 THC2528011 O46172_NEPCL (O46172) Dragline silkprotein spidroin 1 (Fragment), partial (7%) [THC2528011] A_23_P206568A_23_P206568 Unknown A_24_P383934 A_24_P383934 Unknown NM_015341 NCAPHHomo sapiens non-SMC condensin I complex, subunit H (NCAPH), mRNA[NM_015341] AK092875 AK092875 Homo sapiens cDNA FLJ35556 fis, cloneSPLEN2004844. [AK092875] THC2712687 THC2712687 Unknown NM_005357 LIPEHomo sapiens lipase, hormone-sensitive (LIPE), mRNA [NM_005357]NM_198253 TERT Homo sapiens telomerase reverse transcriptase (TERT),transcript variant 1, mRNA [NM_198253] THC2520542 THC2520542Q9XDH2_MYCTU (Q9XDH2) Proline-rich mucin homolog, partial (3%)[THC2520542] NM_144670 A2ML1 Homo sapiens alpha-2-macroglobulin-like 1(A2ML1), mRNA [NM_144670] A_24_P638608 A_24_P638608 Unknown THC2725746THC2725746 Unknown AK129982 AK129982 Homo sapiens cDNA FLJ26472 fis,clone KDN04506. [AK129982] NM_198253 TERT Homo sapiens telomerasereverse transcriptase (TERT), transcript variant 1, mRNA [NM_198253]NM_002102 GYPE Homo sapiens glycophorin E (GYPE), transcript variant 1,mRNA [NM_002102] THC2732966 THC2732966 Unknown BC040619 LOC346887 Homosapiens similar to solute carrier family 16 (monocarboxylic acidtransporters), member 14, mRNA (cDNA clone IMAGE: 5726657). [BC040619]NM_198253 TERT Homo sapiens telomerase reverse transcriptase (TERT),transcript variant 1, mRNA [NM_198253] NM_178831 GATS Homo sapiensopposite strand transcription unit to STAG3 (GATS), mRNA [NM_178831]NM_018125 ARHGEF10L Homo sapiens Rho guanine nucleotide exchange factor(GEF) 10- like (ARHGEF10L), transcript variant 1, mRNA [NM_018125]XM_001133211 LOC729003 PREDICTED: Homo sapiens hypothetical proteinLOC729003 (LOC729003), mRNA [XM_001133211] NM_016379 VCX3A Homo sapiensvariable charge, X-linked 3A (VCX3A), mRNA [NM_016379] NM_198253 TERTHomo sapiens telomerase reverse transcriptase (TERT), transcript variant1, mRNA [NM_198253] ENST00000359466 ENST00000359466 chromosome X openreading frame 18 (CXorf18), misc RNA [Source: RefSeq_dna; Acc:XR_018001] [ENST00000359466] NM_033059 KRTAP4-14 Homo sapiens keratinassociated protein 4-14 (KRTAP4-14), mRNA [NM_033059] NM_016423 ZNF219Homo sapiens zinc fmger protein 219 (ZNF219), mRNA [NM_016423]A_24_P940079 A_24_P940079 Unknown AF116718 HDLBP Homo sapiens PRO2900mRNA, complete cds. [AF116718] NM_198253 TERT Homo sapiens telomerasereverse transcriptase (TERT), transcript variant 1, mRNA [NM_198253]AL512711 HDAC10 Homo sapiens mRNA; cDNA DKEZp761B039 (from cloneDKFZp761B039). [AL512711] AK056449 AK056449 Homo sapiens cDNA FLJ31887fis, clone NT2RP7003050. [AK056449] NM_001008661 CCBL2 Homo sapienscysteine conjugate-beta lyase 2 (CCBL2), transcript variant 1, mRNA[NM_001008661] NM_020932 MAGEE1 Homo sapiens melanoma antigen family E,1 (MAGEE1), mRNA [NM_020932] NM_018402 IL26 Homo sapiens interleukin 26(IL26), mRNA [NM_018402] ENST00000357697 ENST00000357697 UnknownA_24_P843921 A_24_P843921 Unknown NM_198253 TERT Homo sapiens telomerasereverse transcriptase (TERT), transcript variant 1, mRNA [NM_198253]NM_198253 TERT Homo sapiens telomerase reverse transcriptase (TERT),transcript variant 1, mRNA [NM_198253] NM_130766 SKIP Homo sapiensskeletal muscle and kidney enriched inositol phosphatase (SKIP),transcript variant 2, mRNA [NM_130766] NM_002617 PEX10 Homo sapiensperoxisome biogenesis factor 10 (PEX10), transcript variant 2, mRNA[NM_002617] NM_173833 SCARA5 Homo sapiens scavenger receptor class A,member 5 (putative) (SCARA5), mRNA [NM_173833] NM_152339 SPATA2L Homosapiens spermatogenesis associated 2-like (SPATA2L), mRNA [NM_152339]NM_007185 TNRC4 Homo sapiens trinucleotide repeat containing 4 (TNRC4),mRNA [NM_007185] NM_182688 UBE2G2 Homo sapiens ubiquitin-conjugatingenzyme E2G 2 (UBC7 homolog, yeast) (UBE2G2), transcript variant 2, mRNA[NM_182688] A_24_P636974 A_24_P636974 Unknown NM_015901 NUDT13 Homosapiens nudix (nucleoside diphosphate linked moiety X)-type motif 13(NUDT13), mRNA [NM_015901] NM_002141 HOXA4 Homo sapiens homeobox A4(HOXA4), mRNA [NM_002141] NM_001837 CCR3 Homo sapiens chemokine (C-Cmotif) receptor 3 (CCR3), transcript variant 1, mRNA [NM_001837]NM_201999 ELF2 Homo sapiens E74-like factor 2 (ets domain transcriptionfactor) (ELF2), transcript variant 1, mRNA [NM_201999] AK000420 AK000420Homo sapiens cDNA FLJ20413 fis, clone KAT02170. [AK000420] NM_024812BAALC Homo sapiens brain and acute leukemia, cytoplasmic (BAALC),transcript variant 1, mRNA [NM_024812] A_23_P129405 A_23_P129405 UnknownNM_000539 RHO Homo sapiens rhodopsin (opsin 2, rod pigment) (retinitispigmentosa 4, autosomal dominant) (RHO), mRNA [NM_000539] NM_198253 TERTHomo sapiens telomerase reverse transcriptase (TERT), transcript variant1, mRNA [NM_198253] XM_372498 LOC390427 PREDICTED: Homo sapiens similarto TBP-associated factor 15 isoform 1 (LOC390427), mRNA [XM_372498]THC2726959 THC2726959 Unknown THC2760960 THC2760960 Unknown THC2718728THC2718728 Unknown NM_173728 ARHGEF15 Homo sapiens Rho guaninenucleotide exchange factor (GEF) 15 (ARHGEF15), mRNA [NM_173728]NM_198253 TERT Homo sapiens telomerase reverse transcriptase (TERT),transcript variant 1, mRNA [NM_198253] THC2667666 THC2667666 UnknownA_24_P636834 A_24_P636834 Unknown NM_173078 SLITRK4 Homo sapiens SLITand NTRK-like family, member 4 (SLITRK4), mRNA [NM_173078] NM_002307LGALS7 Homo sapiens lectin, galactoside-binding, soluble, 7 (galectin 7)(LGALS7), mRNA [NM_002307] ENST00000248668 LRFN1 Leucine-rich repeat andfibronectin type III domain-containing protein 1 (Fragment). [Source:Uniprot/SPTREMBL; Acc: Q9P244] [ENST00000248668] THC2532155 THC2532155Q8K2W0_MOUSE (Q8K2W0) Procollagen, type IX, alpha 2, partial (3%)[THC2532155] ENST00000325151 ENST00000325151 Small inducible cytokineA27 precursor (CCL27) (CC chemokine ILC) (IL-11 R-alpha-locus chemokine)(Skinkine) (ESkine) (Cutaneous T-cell-attracting chemokine) (CTACK).[Source: Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_006266RALGDS Homo sapiens ral guanine nucleotide dissociation stimulator(RALGDS), transcript variant 1, mRNA [NM_006266] NM_198253 TERT Homosapiens telomerase reverse transcriptase (TERT), transcript variant 1,mRNA [NM_198253] NM_004703 RABEP1 Homo sapiens rabaptin, RAB GTPasebinding effector protein 1 (RABEP1), transcript variant 1, mRNA[NM_004703] NM_001138 AGRP Homo sapiens agouti related protein homolog(mouse) (AGRP), transcript variant 1, mRNA [NM_001138] XM_001133403LOC732417 PREDICTED: Homo sapiens hypothetical protein LOC732417(LOC732417), mRNA [XM_001133403] NM_207377 UNQ9438 Homo sapiens TIMM9(UNQ9438), mRNA [NM_207377] NM_002307 LGALS7 Homo sapiens lectin,galactoside-binding, soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307]BI262095 BI262095 BI262095 602953519T1 NIH_MGC_99 Homo sapiens cDNAclone IMAGE: 5087621 3′, mRNA sequence [BI262095] NM_145234 CHRDL1 Homosapiens chordin-like 1 (CHRDL1), mRNA [NM_145234] NM_016219 MAN1B1 Homosapiens mannosidase, alpha, class 1B, member 1 (MAN1B1), mRNA[NM_016219] NM_018670 MESP1 Homo sapiens mesoderm posterior 1 homolog(mouse) (MESP1), mRNA [NM_018670] NM_004819 SYMPK Homo sapiens symplekin(SYMPK), mRNA [NM_004819] BU561469 BU561469 AGENCOURT_10278709NIH_MGC_82 Homo sapiens cDNA clone IMAGE: 6592525 5′, mRNA sequence[BU561469] NM_015088 TNRC6B Homo sapiens trinucleotide repeat containing6B (TNRC6B), transcript variant 1, mRNA [NM_015088] ENST00000299974ENST00000299974 ATP/GTP binding protein-like 1 [Source: RefSeq_peptide;Acc: NP_689549] [ENST00000299974] NM_175734 C17orf74 Homo sapienschromosome 17 open reading frame 74 (C17orf74), mRNA [NM_175734]NM_152384 BBS5 Homo sapiens Bardet-Biedl syndrome 5 (BBS5), mRNA[NM_152384] J03651 J03651 Human DF3 breast carcinoma-associated antigenmRNA, partial cds. [J03651] A_23_P46070 A_23_P46070 Unknown NM_004750CRLF1 Homo sapiens cytokine receptor-like factor 1 (CRLF1), mRNA[NM_004750] NM_003508 FZD9 Homo sapiens frizzled homolog 9 (Drosophila)(FZD9), mRNA [NM_003508] AL566332 AL566332 AL566332 AL566332 Homosapiens FETAL BRAIN Homo sapiens cDNA clone CS0DF015YB18 3-PRIME, mRNAsequence [AL566332] A_24_P144625 A_24_P144625 Unknown AA418814 AA418814AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE:767978 3′, mRNA sequence [AA418814] A_32_P186382 A_32_P186382 UnknownNM_203374 ZNF784 Homo sapiens zinc finger protein 784 (ZNF784), mRNA[NM_203374] ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI)(Serpin B1) (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI).[Source: Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183FOXD3 Homo sapiens forkhead box D3 (FOXD3), mRNA [NM_012183]ENST00000328043 ENST00000328043 LRP11 protein (Fragment). [Source:Uniprot/SPTREMBL; Acc: Q96AT3] [ENST00000328043] NM_019105 TNXB Homosapiens tenascin XB (TNXB), transcript variant XB, mRNA [NM_019105]ENST00000325371 ENST00000325371 Homo sapiens cDNA clone IMAGE: 4819956.[BC018035] THC2504037 THC2504037 ALU1_HUMAN (P39188) Alu subfamily Jsequence contamination warning entry, partial (7%) [THC2504037]NM_174903 RNF151 Homo sapiens ring finger protein 151 (RNF151), mRNA[NM_174903] NM_022555 HLA-DRB3 Homo sapiens major histocompatibilitycomplex, class II, DR beta 3 (HLA-DRB3), mRNA [NM_022555]ENST00000360514 ENST00000360514 Homo sapiens hypothetical LOC339483,mRNA (cDNA clone MGC: 52427 IMAGE: 4872239), complete cds. [BC041632]THC2694242 THC2694242 Unknown NM_138763 BAX Homo sapiens BCL2-associatedX protein (BAX), transcript variant delta, mRNA [NM_138763] NM_002691POLD1 Homo sapiens polymerase (DNA directed), delta 1, catalytic subunit125 kDa (POLD1), mRNA [NM_002691] ENST00000331849 FLJ20581 CDNA FLJ20581fis, clone REC00491. [Source: Uniprot/SPTREMBL; Acc: Q9NWV3][ENST00000331849] XR_018717 FDPSL4 PREDICTED: Homo sapiens similar tofarnesyl diphosphate synthase (LOC390580), mRNA [XR_018717] NM_152418WDR21C Homo sapiens WD repeat domain 21C (WDR21C), mRNA [NM_152418]NM_203304 RKHD1 Homo sapiens ring fmger and KH domain containing 1(RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiens leucine-richrepeat-containing G protein-coupled receptor 4 (LGR4), mRNA [NM_018490]NM_001611 ACP5 Homo sapiens acid phosphatase 5, tartrate resistant(ACP5), mRNA [NM_001611] NM_174976 ZDHHC22 Homo sapiens zinc finger,DHHC-type containing 22 (ZDHHC22), mRNA [NM_174976] CV575560 CV575560oe37f10.y1 Human keratoconus cornea, unamplified, (od [CV575560]

TABLE 15 Gene list generated at the inclusion criteria of p ≦ 0.05 andthe log-median-ratio being at least “1” or above. GenBank Accession GeneName Description A_24_P843921 A_24_P843921 Unknown NM_198253 TERT Homosapiens telomerase reverse transcriptase (TERT), transcript variant 1,mRNA [NM_198253] NM_198253 TERT Homo sapiens telomerase reversetranscriptase (TERT), transcript variant 1, mRNA [NM_198253] NM_130766SKIP Homo sapiens skeletal muscle and kidney enriched inositolphosphatase (SKIP), transcript variant 2, mRNA [NM_130766] NM_002617PEX10 Homo sapiens peroxisome biogenesis factor 10 (PEX10), transcriptvariant 2, mRNA [NM_002617] NM_173833 SCARA5 Homo sapiens scavengerreceptor class A, member 5 (putative) (SCARA5), mRNA [NM_173833]NM_152339 SPATA2L Homo sapiens spermatogenesis associated 2-like(SPATA2L), mRNA [NM_152339] NM_007185 TNRC4 Homo sapiens trinucleotiderepeat containing 4 (TNRC4), mRNA [NM_007185] NM_182688 UBE2G2 Homosapiens ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)(UBE2G2), transcript variant 2, mRNA [NM_182688] A_24_P636974A_24_P636974 Unknown NM_015901 NUDT13 Homo sapiens nudix (nucleosidediphosphate linked moiety X)-type motif 13 (NUDT13), mRNA [NM_015901]NM_002141 HOXA4 Homo sapiens homeobox A4 (HOXA4), mRNA [NM_002141]NM_001837 CCR3 Homo sapiens chemokine (C-C motif) receptor 3 (CCR3),transcript variant 1, mRNA [NM_001837] NM_201999 ELF2 Homo sapiensE74-like factor 2 (ets domain transcription factor) (ELF2), transcriptvariant 1, mRNA [NM_201999] AK000420 AK000420 Homo sapiens cDNA FLJ20413fis, clone KAT02170. [AK000420] NM_024812 BAALC Homo sapiens brain andacute leukemia, cytoplasmic (BAALC), transcript variant 1, mRNA[NM_024812] A_23_P129405 A_23_P129405 Unknown NM_000539 RHO Homo sapiensrhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomaldominant) (RHO), mRNA [NM_000539] NM_198253 TERT Homo sapiens telomerasereverse transcriptase (TERT), transcript variant 1, mRNA [NM_198253]XM_372498 LOC390427 PREDICTED: Homo sapiens similar to TBP-associatedfactor 15 isoform 1 (LOC390427), mRNA [XM_372498] THC2726959 THC2726959Unknown THC2760960 THC2760960 Unknown THC2718728 THC2718728 UnknownNM_173728 ARHGEF15 Homo sapiens Rho guanine nucleotide exchange factor(GEF) 15 (ARHGEF15), mRNA [NM_173728] NM_198253 TERT Homo sapienstelomerase reverse transcriptase (TERT), transcript variant 1, mRNA[NM_198253] THC2667666 THC2667666 Unknown A_24_P636834 A_24_P636834Unknown NM_173078 SLITRK4 Homo sapiens SLIT and NTRK-like family, member4 (SLITRK4), mRNA [NM_173078] NM_002307 LGALS7 Homo sapiens lectin,galactoside-binding, soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307]ENST00000248668 LRFN1 Leucine-rich repeat and fibronectin type IIIdomain-containing protein 1 (Fragment). [Source: Uniprot/SPTREMBL; Acc:Q9P244] [ENST00000248668] THC2532155 THC2532155 Q8K2W0_MOUSE (Q8K2W0)Procollagen, type IX, alpha 2, partial (3%) [THC2532155] ENST00000325151ENST00000325151 Small inducible cytokine A27 precursor (CCL27) (CCchemokine ILC) (IL-11 R-alpha-locus chemokine) (Skinkine) (ESkine)(Cutaneous T-cell-attracting chemokine) (CTACK). [Source:Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_006266 RALGDS Homosapiens ral guanine nucleotide dissociation stimulator (RALGDS),transcript variant 1, mRNA [NM_006266] NM_198253 TERT Homo sapienstelomerase reverse transcriptase (TERT), transcript variant 1, mRNA[NM_198253] NM_004703 RABEP1 Homo sapiens rabaptin, RAB GTPase bindingeffector protein 1 (RABEP1), transcript variant 1, mRNA [NM_004703]NM_001138 AGRP Homo sapiens agouti related protein homolog (mouse)(AGRP), transcript variant 1, mRNA [NM_001138] XM_001133403 LOC732417PREDICTED: Homo sapiens hypothetical protein LOC732417 (LOC732417), mRNA[XM_001133403] NM_207377 UNQ9438 Homo sapiens TIMM9 (UNQ9438), mRNA[NM_207377] NM_002307 LGALS7 Homo sapiens lectin, galactoside-binding,soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307] BI262095 BI262095BI262095 602953519T1 NIH_MGC_99 Homo sapiens cDNA clone IMAGE: 50876213′, mRNA sequence [BI262095] NM_145234 CHRDL1 Homo sapiens chordin-like1 (CHRDL1), mRNA [NM_145234] NM_016219 MAN1B1 Homo sapiens mannosidase,alpha, class 1B, member 1 (MAN1B1), mRNA [NM_016219] NM_018670 MESP1Homo sapiens mesoderm posterior 1 homolog (mouse) (MESP1), mRNA[NM_018670] NM_004819 SYMPK Homo sapiens symplekin (SYMPK), mRNA[NM_004819] BU561469 BU561469 AGENCOURT_10278709 NIH_MGC_82 Homo sapienscDNA clone IMAGE: 6592525 5′, mRNA sequence [BU561469] NM_015088 TNRC6BHomo sapiens trinucleotide repeat containing 6B (TNRC6B), transcriptvariant 1, mRNA [NM_015088] ENST00000299974 ENST00000299974 ATP/GTPbinding protein-like 1 [Source: RefSeq_peptide; Acc: NP_689549][ENST00000299974] NM_175734 C17orf74 Homo sapiens chromosome 17 openreading frame 74 (C17orf74), mRNA [NM_175734] NM_152384 BBS5 Homosapiens Bardet-Biedl syndrome 5 (BBS5), mRNA [NM_152384] J03651 J03651Human DF3 breast carcinoma-associated antigen mRNA, partial cds.[J03651] A_23_P46070 A_23_P46070 Unknown NM_004750 CRLF1 Homo sapienscytokine receptor-like factor 1 (CRLF1), mRNA [NM_004750] NM_003508 FZD9Homo sapiens frizzled homolog 9 (Drosophila) (FLD9), mRNA [NM_003508]AL566332 AL566332 AL566332 AL566332 Homo sapiens FETAL BRAIN Homosapiens cDNA clone CS0DF015YB18 3-PRIME, mRNA sequence [AL566332]A_24_P144625 A_24_P144625 Unknown AA418814 AA418814 AA418814 zw01a02.s1Soares_NhHMPu_S1 Homo sapiens cDNA clone IMAGE: 767978 3′, mRNA sequence[AA418814] A_32_P186382 A_32_P186382 Unknown NM_203374 ZNF784 Homosapiens zinc finger protein 784 (ZNF784), mRNA [NM_203374]ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI) (Serpin B1)(Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI). [Source:Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183 FOXD3 Homosapiens forkhead box D3 (FOXD3), mRNA [NM_012183] ENST00000328043ENST00000328043 LRP11 protein (Fragment). [Source: Uniprot/SPTREMBL;Acc: Q96AT3] [ENST00000328043] NM_019105 TNXB Homo sapiens tenascin XB(TNXB), transcript variant XB, mRNA [NM_019105] ENST00000325371ENST00000325371 Homo sapiens cDNA clone IMAGE: 4819956. [BC018035]THC2504037 THC2504037 ALU1_HUMAN (P39188) Alu subfamily J sequencecontamination warning entry, partial (7%) [THC2504037] NM_174903 RNF151Homo sapiens ring finger protein 151 (RNF151), mRNA [NM_174903]NM_022555 HLA-DRB3 Homo sapiens major histocompatibility complex, classII, DR beta 3 (HLA-DRB3), mRNA [NM_022555] ENST00000360514ENST00000360514 Homo sapiens hypothetical LOC339483, mRNA (cDNA cloneMGC: 52427 IMAGE: 4872239), complete cds. [BC041632] THC2694242THC2694242 Unknown NM_138763 BAX Homo sapiens BCL2-associated X protein(BAX), transcript variant delta, mRNA [NM_138763] NM_002691 POLD1 Homosapiens polymerase (DNA directed), delta 1, catalytic subunit 125 kDa(POLD1), mRNA [NM_002691] ENST00000331849 FLJ20581 CDNA FLJ20581 fis,clone REC00491. [Source: Uniprot/SPTREMBL; Acc: Q9NWV3][ENST00000331849] XR_018717 FDPSL4 PREDICTED: Homo sapiens similar tofarnesyl diphosphate synthase (LOC390580), mRNA [XR_018717] NM_152418WDR21C Homo sapiens WD repeat domain 21C (WDR21C), mRNA [NM_152418]NM_203304 RKHD1 Homo sapiens ring finger and KH domain containing 1(RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiens leucine-richrepeat-containing G protein-coupled receptor 4 (LGR4), mRNA [NM_018490]NM_001611 ACP5 Homo sapiens acid phosphatase 5, tartrate resistant(ACP5), mRNA [NM_001611] NM_174976 ZDHHC22 Homo sapiens zinc finger,DHHC-type containing 22 (ZDHHC22), mRNA [NM_174976] CV575560 CV575560oe37f10.y1 Human keratoconus cornea, unamplified, (od [CV575560]

TABLE 16 Gene list generated at the inclusion criteria of p ≦ 0.001.GenBank Accession GeneName Description NM_006709 EHMT2 Homo sapienseuchromatic histone-lysine N-methyltransferase 2 (EHMT2), transcriptvariant NG36/G9a, mRNA [NM_006709] NM_000978 RPL23 Homo sapiensribosomal protein L23 (RPL23), mRNA [NM_000978] NM_001017 RPS13 Homosapiens ribosomal protein S13 (RPS13), mRNA [NM_001017] A_24_P50489A_24_P50489 Unknown NM_139280 ORMDL3 Homo sapiens ORM1-like 3 (S.cerevisiae) (ORMDL3), mRNA [NM_139280] NM_000979 RPL18 Homo sapiensribosomal protein L18 (RPL18), mRNA [NM_000979] A_32_P230059A_32_P230059 Unknown XR_019168 LOC391847 PREDICTED: Homo sapiens similarto ribosomal protein L19 (LOC391847), mRNA [XR_019168] BC065737 BC065737Homo sapiens cDNA clone IMAGE: 30404477, partial cds. [BC065737] M55405MUC3A Homo sapiens mucin (MUC-3) mRNA, partial cds. [M55405] AF335478KLK3 Homo sapiens prostate-specific antigen variant 2 mRNA, completecds, alternatively spliced. [AF335478] NM_018090 NECAP2 Homo sapiensNECAP endocytosis associated 2 (NECAP2), mRNA [NM_018090] NM_001080484KIAA1751 Homo sapiens KIAA1751 (KIAA1751), mRNA [NM_001080484]A_24_P144163 A_24_P144163 Unknown NM_013328 PYCR2 Homo sapienspyrroline-5-carboxylate reductase family, member 2 (PYCR2), mRNA[NM_013328] NM_052854 CREB3L1 Homo sapiens cAMP responsive elementbinding protein 3-like 1 (CREB3L1), mRNA [NM_052854] A_32_P128781A_32_P128781 Unknown NM_000610 CD44 Homo sapiens CD44 molecule (Indianblood group) (CD44), transcript variant 1, mRNA [NM_000610] THC2718728THC2718728 Unknown NM_002085 GPX4 Homo sapiens glutathione peroxidase 4(phospholipid hydroperoxidase) (GPX4), transcript variant 1, mRNA[NM_002085] NM_004657 SDPR Homo sapiens serum deprivation response(phosphatidylserine binding protein) (SDPR), mRNA [NM_004657] NM_000996RPL35A Homo sapiens ribosomal protein L35a (RPL35A), mRNA [NM_000996]NM_005601 NKG7 Homo sapiens natural killer cell group 7 sequence (NKG7),mRNA [NM_005601] NM_175744 RHOC Homo sapiens ras homolog gene family,member C (RHOC), transcript variant 1, mRNA [NM_175744] ENST00000333650ENST00000333650 PREDICTED: Homo sapiens similar to 60S ribosomal proteinL14 (CAG-ISL 7) (LOC730747), mRNA [XR_015398] THC2527647 THC2527647Q59GY2_HUMAN (Q59GY2) Ribosomal protein L4 variant (Fragment), partial(51%) [THC2527647] CR594528 CR594528 full-length cDNA clone CS0DM002YC17of Fetal liver of Homo sapiens (human) [CR594528] NM_006013 RPL10 Homosapiens ribosomal protein L10 (RPL10), mRNA [NM_006013] A_32_P11425A_32_P11425 Unknown NM_001028 RPS25 Homo sapiens ribosomal protein S25(RPS25), mRNA [NM_001028] NM_006482 DYRK2 Homo sapiens dual-specificitytyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2), transcriptvariant 2, mRNA [NM_006482] NM_025004 CCDC15 Homo sapiens coiled-coildomain containing 15 (CCDC15), mRNA [NM_025004] A_24_P333112A_24_P333112 Unknown NM_015894 STMN3 Homo sapiens stathmin-like 3(STMN3), mRNA [NM_015894] NM_001803 CD52 Homo sapiens CD52 molecule(CD52), mRNA [NM_001803] NM_000984 RPL23A Homo sapiens ribosomal proteinL23a (RPL23A), mRNA [NM_000984] NM_000486 AQP2 Homo sapiens aquaporin 2(collecting duct) (AQP2), mRNA [NM_000486] NM_001000 RPL39 Homo sapiensribosomal protein L39 (RPL39), mRNA [NM_001000] NM_001568 EIF3S6 Homosapiens eukaryotic translation initiation factor 3, subunit 6 48 kDa(EIF3S6), mRNA [NM_001568] NM_001032 RPS29 Homo sapiens ribosomalprotein S29 (RPS29), transcript variant 1, mRNA [NM_001032] NM_005553KRTAP5-9 Homo sapiens keratin associated protein 5-9 (KRTAP5-9), mRNA[NM_005553] NM_006280 SSR4 Homo sapiens signal sequence receptor, delta(translocon- associated protein delta) (SSR4), mRNA [NM_006280]A_24_P212605 A_24_P212605 Unknown XR_018868 LOC645000 PREDICTED: Homosapiens similar to 40S ribosomal protein S3 (LOC645000), mRNA[XR_018868] A_24_P392661 A_24_P392661 Unknown NM_018127 ELAC2 Homosapiens elaC homolog 2 (E. coli) (ELAC2), mRNA [NM_018127] NM_175863ARID1B Homo sapiens AT rich interactive domain 1B (SWI1-like) (ARID1B),transcript variant 3, mRNA [NM_175863] NM_030915 LBH Homo sapiens limbbud and heart development homolog (mouse) (LBH), mRNA [NM_030915]NM_000968 RPL4 Homo sapiens ribosomal protein L4 (RPL4), mRNA[NM_000968] NM_001014 RPS10 Homo sapiens ribosomal protein S10 (RPS10),mRNA [NM_001014] A_24_P160920 A_24_P160920 Unknown NM_014183 DYNLRB1Homo sapiens dynein, light chain, roadblock-type 1 (DYNLRB1), mRNA[NM_014183] ENST00000312528 ENST00000312528 Unknown BC104478 RPL21 Homosapiens ribosomal protein L21, mRNA (cDNA clone IMAGE: 6605832),complete cds. [BC104478] THC2481836 THC2481836 Q412F2_KINRA (Q412F2)MOSC, partial (10%) [THC2481836] NM_015088 TNRC6B Homo sapienstrinucleotide repeat containing 6B (TNRC6B), transcript variant 1, mRNA[NM_015088] NM_015414 RPL36 Homo sapiens ribosomal protein L36 (RPL36),transcript variant 2, mRNA [NM_015414] CR933606 C20orf80 Homo sapiensmRNA; cDNA DKFZp686M08106 (from clone DKFZp686M08106). [CR933606]A_24_P332441 A_24_P332441 Unknown BC052613 LOC728131 Homo sapiens cDNAclone MGC: 59872 IMAGE: 6301163, complete cds. [BC052613] NM_020939CPNE5 Homo sapiens copine V (CPNE5), mRNA [NM_020939] NM_003973 RPL14Homo sapiens ribosomal protein L14 (RPL14), transcript variant 2, mRNA[NM_003973] NM_032378 EEF1D Homo sapiens eukaryotic translationelongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D),transcript variant 1, mRNA [NM_032378] NM_001014 RPS10 Homo sapiensribosomal protein S10 (RPS10), mRNA [NM_001014] A_24_P853410A_24_P853410 Unknown XR_019052 LOC391738 PREDICTED: Homo sapiens similarto 60S ribosomal protein L29 (Cell surface heparin-binding protein HIP)(LOC391738), mRNA [XR_019052] NM_032351 MRPL45 Homo sapiensmitochondrial ribosomal protein L45 (MRPL45), nuclear gene encodingmitochondrial protein, mRNA [NM_032351] XM_379885 hCG_2023776 PREDICTED:Homo sapiens similar to Heterogeneous nuclear ribonucleoprotein A1(Helix-destabilizing protein) (Single-strand binding protein) (hnRNPcore protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed)(LOC402562), mRNA [XM_379885] AA279208 AA279208 AA279208 zs83e07.s1NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE: 704100 3′, mRNA sequence[AA279208] NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein(MGC70863), transcript variant 1, mRNA [NM_203477] NM_032476 MRPS6 Homosapiens mitochondrial ribosomal protein S6 (MRPS6), nuclear geneencoding mitochondrial protein, mRNA [NM_032476] NM_001005472 LOC388524Homo sapiens similar to Laminin receptor 1 (LOC388524), mRNA[NM_001005472] THC2717131 THC2717131 Q7NI46_GLOVI (Q7NI46) Cytochromec550, partial (8%) [THC2717131] XR_018975 LOC389644 PREDICTED: Homosapiens similar to ribosomal protein L5 (LOC389644), mRNA [XR_018975]A_24_P306968 A_24_P306968 Unknown NM_194302 CCDC108 Homo sapienscoiled-coil domain containing 108 (CCDC108), transcript variant 1, mRNA[NM_194302] NM_173680 ZNF775 Homo sapiens zinc finger protein 775(ZNF775), mRNA [NM_173680] NM_001344 DAD1 Homo sapiens defender againstcell death 1 (DAD1), mRNA [NM_001344] NM_016085 C2orf28 Homo sapienschromosome 2 open reading frame 28 (C2orf28), transcript variant 1, mRNA[NM_016085] NM_031901 MRPS21 Homo sapiens mitochondrial ribosomalprotein S21 (MRPS21), nuclear gene encoding mitochondrial protein,transcript variant 1, mRNA [NM_031901] NM_000999 RPL38 Homo sapiensribosomal protein L38 (RPL38), transcript variant 1, mRNA [NM_000999]NM_001988 EVPL Homo sapiens envoplakin (EVPL), mRNA [NM_001988]NM_203374 ZNF784 Homo sapiens zinc finger protein 784 (ZNF784), mRNA[NM_203374] NR_000029 RPL23AP7 Homo sapiens ribosomal protein L23apseudogene 7 (RPL23AP7) on chromosome 2 [NR_000029] THC2537928THC2537928 HUMRPL4X ribosomal protein L4 {Homo sapiens} (exp = −1; wgp =0; cg = 0), partial (34%) [THC2600839] NM_001001 RPL36AL Homo sapiensribosomal protein L36a-like (RPL36AL), mRNA [NM_001001] AK024389FLJ14327 Homo sapiens cDNA FLJ14327 fis, clone PLACE4000250. [AK024389]NM_007104 RPL10A Homo sapiens ribosomal protein L10a (RPL10A), mRNA[NM_007104] NM_001018 RPS15 Homo sapiens ribosomal protein S15 (RPS15),mRNA [NM_001018] NM_003752 EIF3S8 Homo sapiens eukaryotic translationinitiation factor 3, subunit 8, 110 kDa (EIF3S8), transcript variant 1,mRNA [NM_003752] A_24_P161459 A_24_P161459 Unknown NM_178449 TIP39 Homosapiens tuberoinfundibular 39 residue protein precursor (TIP39), mRNA[NM_178449] XR_018430 LOC391102 PREDICTED: Homo sapiens similar to 60Sacidic ribosomal protein P0 (L10E) (LOC391102), mRNA [XR_018430]NM_002490 NDUFA6 Homo sapiens NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 6, 14 kDa (NDUFA6), nuclear gene encoding mitochondrialprotein, mRNA [NM_002490] A_24_P358578 A_24_P358578 Unknown NM_000989RPL30 Homo sapiens ribosomal protein L30 (RPL30), mRNA [NM_000989]BC014606 BC014606 Homo sapiens cDNA clone IMAGE: 4826808. [BC014606]XR_015710 LOC731048 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L17 (L23) (LOC731048), mRNA [XR_015710] XM_928198 LOC645161PREDICTED: Homo sapiens similar to 60S ribosomal protein L12(LOC645161), mRNA [XM_928198] XR_017813 RPLP0-like PREDICTED: Homosapiens similar to ribosomal protein P0 (RPLP0-like), misc RNA[XR_017813] NM_001011724 RP11-78J21.1 Homo sapiens heterogeneous nuclearribonucleoprotein A1-like (LOC144983), transcript variant 1, mRNA[NM_001011724] NM_024600 C16orf30 Homo sapiens chromosome 16 openreading frame 30 (C16orf30), mRNA [NM_024600] NM_000761 CYP1A2 Homosapiens cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2),mRNA [NM_000761] NM_002568 PABPC1 Homo sapiens poly(A) binding protein,cytoplasmic 1 (PABPC1), mRNA [NM_002568] BC030568 LOC376693 Homo sapienshypothetical LOC376693, mRNA (cDNA clone MGC: 45392 IMAGE: 5526694),complete cds. [BC030568] NM_198053 CD247 Homo sapiens CD247 molecule(CD247), transcript variant 1, mRNA [NM_198053] NM_080425 GNAS Homosapiens GNAS complex locus (GNAS), transcript variant 2, mRNA[NM_080425] XM_087499 LOC152663 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7a (LOC152663), mRNA [XM_087499] A_24_P650893A_24_P650893 Unknown NM_012329 MMD Homo sapiens monocyte to macrophagedifferentiation-associated (MMD), mRNA [NM_012329] XR_019277 LOC391719PREDICTED: Homo sapiens similar to ribosomal protein L19 (LOC391719),mRNA [XR_019277] A_24_P238426 A_24_P238426 Unknown NM_003576 STK24 Homosapiens serine/threonine kinase 24 (STE20 homolog, yeast) (STK24),transcript variant 1, mRNA [NM_003576] NM_153719 NUP62 Homo sapiensnucleoporin 62 kDa (NUP62), transcript variant 1, mRNA [NM_153719]NM_002539 ODC1 Homo sapiens ornithine decarboxylase 1 (ODC1), mRNA[NM_002539] NM_001005472 LOC388524 Homo sapiens similar to Lamininreceptor 1 (LOC388524), mRNA [NM_001005472] NM_000454 SOD1 Homo sapienssuperoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1(adult)) (SOD1), mRNA [NM_000454] NM_005594 NACA Homo sapiensnascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA[NM_005594] NM_052871 MGC4677 Homo sapiens hypothetical protein MGC4677(MGC4677), mRNA [NM_052871] NM_006826 YWHAQ Homo sapiens tyrosine3-monooxygenase/tryptophan 5- monooxygenase activation protein, thetapolypeptide (YWHAQ), mRNA [NM_006826] ENST00000310391 ENST00000310391Unknown NM_000398 CYB5R3 Homo sapiens cytochrome b5 reductase 3(CYB5R3), transcript variant M, mRNA [NM_000398] NM_032932 RAB11FIP4Homo sapiens RAB11 family interacting protein 4 (class II) (RAB11FIP4),mRNA [NM_032932] XR_018048 LOC646161 PREDICTED: Homo sapiens similar to60S ribosomal protein L26 (LOC646161), mRNA [XR_018048] BC006438BC006438 Homo sapiens cDNA clone MGC: 13162 IMAGE: 3010103, completecds. [BC006438] NM_002121 HLA-DPB1 Homo sapiens major histocompatibilitycomplex, class II, DP beta 1 (HLA-DPB1), mRNA [NM_002121] NM_013939OR10H2 Homo sapiens olfactory receptor, family 10, subfamily H, member 2(OR10H2), mRNA [NM_013939] NM_001030 RPS27 Homo sapiens ribosomalprotein S27 (metallopanstimulin 1) (RPS27), mRNA [NM_001030]ENST00000340005 LOC731959 similar to 60S ribosomal protein L12(LOC644202), mRNA [Source: RefSeq_dna; Acc: XR_016588] [ENST00000340005]NM_015444 TMEM158 Homo sapiens transmembrane protein 158 (TMEM158), mRNA[NM_015444] NM_005340 HINT1 Homo sapiens histidine triad nucleotidebinding protein 1 (HINT1), mRNA [NM_005340] NM_001032 RPS29 Homo sapiensribosomal protein S29 (RPS29), transcript variant 1, mRNA [NM_001032]AF147412 AF147412 Homo sapiens full length insert cDNA clone YP59C02.[AF147412] NM_000732 CD3D Homo sapiens CD3d molecule, delta (CD3-TCRcomplex) (CD3D), transcript variant 1, mRNA [NM_000732] THC2586367THC2586367 Q9D7P1_MOUSE (Q9D7P1) Adult male tongue cDNA, RIKENfull-length enriched library, clone: 2300009C10 product: ribosomalprotein S24, full insert sequence, partial (95%) [THC2586367] BX427435BX427435 BX427435 Homo sapiens FETAL LIVER Homo sapiens cDNA cloneCS0DM010YK16 3-PRIME, mRNA sequence [BX427435] NM_006266 RALGDS Homosapiens ral guanine nucleotide dissociation stimulator (RALGDS),transcript variant 1, mRNA [NM_006266] NM_000978 RPL23 Homo sapiensribosomal protein L23 (RPL23), mRNA [NM_000978] A_24_P195257A_24_P195257 Unknown NM_021103 TMSB10 Homo sapiens thymosin, beta 10(TMSB10), mRNA [NM_021103] XR_018222 RPL31P4 PREDICTED: Homo sapiensribosomal protein L31 pseudogene 4 (RPL31P4), mRNA [XR_018222]ENST00000360514 ENST00000360514 Homo sapiens hypothetical LOC339483,mRNA (cDNA clone MGC: 52427 IMAGE: 4872239), complete cds. [BC041632]NM_006098 GNB2L1 Homo sapiens guanine nucleotide binding protein (Gprotein), beta polypeptide 2-like 1 (GNB2L1), mRNA [NM_006098]A_32_P167577 A_32_P167577 Unknown U19144 GAGE3 Human GAGE-3 proteinmRNA, complete cds. [U19144] NM_003973 RPL14 Homo sapiens ribosomalprotein L14 (RPL14), transcript variant 2, mRNA [NM_003973] NM_005950MT1G Homo sapiens metallothionein 1G (MT1G), mRNA [NM_005950] NM_000967RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcript variant 1,mRNA [NM_000967] NM_033251 RPL13 Homo sapiens ribosomal protein L13(RPL13), transcript variant 2, mRNA [NM_033251] A_24_P578641A_24_P578641 Unknown XM_001131279 LOC343851 PREDICTED: Homo sapienssimilar to 40S ribosomal protein S10 (LOC343851), mRNA [XM_001131279]A_32_P233211 A_32_P233211 Unknown NM_178352 LCE1D Homo sapiens latecornified envelope 1D (LCE1D), mRNA [NM_178352] NM_003932 ST13 Homosapiens suppression of tumorigenicity 13 (colon carcinoma) (Hsp70interacting protein) (ST13), mRNA [NM_003932] NM_003295 TPT1 Homosapiens tumor protein, translationally-controlled 1 (TPT1), mRNA[NM_003295] NM_001018 RPS15 Homo sapiens ribosomal protein S15 (RPS15),mRNA [NM_001018] NM_001618 PARP1 Homo sapiens poly (ADP-ribose)polymerase family, member 1 (PARP1), mRNA [NM_001618] A_24_P307255A_24_P307255 Unknown NM_000661 RPL9 Homo sapiens ribosomal protein L9(RPL9), transcript variant 1, mRNA [NM_000661] NM_206833 CTXN1 Homosapiens cortexin 1 (CTXN1), mRNA [NM_206833] NM_005694 COX17 Homosapiens COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)(COX17), nuclear gene encoding mitochondrial protein, mRNA [NM_005694]NM_001080403 FLJ22184 Homo sapiens hypothetical protein FLJ22184(FLJ22184), mRNA [NM_001080403] M36647 UQCRH Homo sapiens mitochondrialhinge protein precursor, mRNA, complete cds. [M36647] NM_001007074 RPL32Homo sapiens ribosomal protein L32 (RPL32), transcript variant 3, mRNA[NM_001007074] A_24_P84408 A_24_P84408 Unknown NM_001003845 SP5 Homosapiens Sp5 transcription factor (SP5), mRNA [NM_001003845]ENST00000303979 ENST00000303979 Unknown NM_014765 TOMM20 Homo sapienstranslocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20),mRNA [NM_014765] XR_018138 LOC392497 PREDICTED: Homo sapiens similar to40S ribosomal protein S6 (LOC392497), mRNA [XR_018138] NM_004048 B2MHomo sapiens beta-2-microglobulin (B2M), mRNA [NM_004048] NM_014328RUSC1 Homo sapiens RUN and SH3 domain containing 1 (RUSC1), mRNA[NM_014328] AK090444 AYTL2 Homo sapiens mRNA for FLJ00365 protein.[AK090444] A_24_P93452 A_24_P93452 Unknown NM_005594 NACA Homo sapiensnascent-polypeptide-associated complex alpha polypeptide (NACA), mRNA[NM_005594] NM_002985 CCL5 Homo sapiens chemokine (C-C motif) ligand 5(CCL5), mRNA [NM_002985] NM_000998 RPL37A Homo sapiens ribosomal proteinL37a (RPL37A), mRNA [NM_000998] NM_000983 RPL22 Homo sapiens ribosomalprotein L22 (RPL22), mRNA [NM_000983] NM_003746 DYNLL1 Homo sapiensdynein, light chain, LC8-type 1 (DYNLL1), transcript variant 3, mRNA[NM_003746] XR_016879 LOC388401 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7 (LOC388401), mRNA [XR_016879] NM_012322 LSM5 Homosapiens LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)(LSM5), mRNA [NM_012322] NM_001404 EEF1G Homo sapiens eukaryotictranslation elongation factor 1 gamma (EEF1G), mRNA [NM_001404]NM_001105 ACVR1 Homo sapiens activin A receptor, type I (ACVR1), mRNA[NM_001105] A_32_P20040 A_32_P20040 Unknown BF931515 BF931515 BF931515IL2-NT0202-141200-308-H03 NT0202 Homo sapiens cDNA, mRNA sequence[BF931515] XR_019504 LOC391126 PREDICTED: Homo sapiens similar to 60Sribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)(LOC391126), mRNA [XR_019504] NM_001021 RPS17 Homo sapiens ribosomalprotein S17 (RPS17), mRNA [NM_001021] NM_006013 RPL10 Homo sapiensribosomal protein L10 (RPL10), mRNA [NM_006013] NM_001028 RPS25 Homosapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] NM_021631 FKSG2Homo sapiens apoptosis inhibitor (FKSG2), mRNA [NM_021631] NM_203477MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863), transcriptvariant 1, mRNA [NM_203477] NM_000986 RPL24 Homo sapiens ribosomalprotein L24 (RPL24), mRNA [NM_000986] A_24_P881608 A_24_P881608 UnknownNM_001022 RPS19 Homo sapiens ribosomal protein S19 (RPS19), mRNA[NM_001022] A_32_P49392 A_32_P49392 Unknown XR_018970 LOC391140PREDICTED: Homo sapiens similar to ribosomal protein L13 (LOC391140),mRNA [XR_018970] NM_000987 RPL26 Homo sapiens ribosomal protein L26(RPL26), mRNA [NM_000987] A_24_P936393 A_24_P936393 Unknown AK074778LOC388152 Homo sapiens cDNA FLJ90297 fis, clone NT2RP2000447, moderatelysimilar to GOLGIN-95. [AK074778] A_32_P95502 A_32_P95502 UnknownNM_001040437 C6orf48 Homo sapiens chromosome 6 open reading frame 48(C6orf48), transcript variant 1, mRNA [NM_001040437] NM_014849 SV2A Homosapiens synaptic vesicle glycoprotein 2A (SV2A), mRNA [NM_014849]AL049447 AL049447 Homo sapiens mRNA; cDNA DKFZp586A0722 (from cloneDKFZp586A0722). [AL049447] NM_024670 SUV39H2 Homo sapiens suppressor ofvariegation 3-9 homolog 2 (Drosophila) (SUV39H2), mRNA [NM_024670]XM_001128309 LOC730663 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L23a (LOC730663), mRNA [XM_001128309] A_32_P194182 A_32_P194182Unknown NM_021148 ZNF273 Homo sapiens zinc finger protein 273 (ZNF273),transcript variant 1, mRNA [NM_021148] NM_017971 MRPL20 Homo sapiensmitochondrial ribosomal protein L20 (MRPL20), nuclear gene encodingmitochondrial protein, mRNA [NM_017971] NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] BM979607 BM979607 BM979607UI-CF-DU1-adt-k-11-0-UI.s1 UI-CF-DU1 Homo sapiens cDNA cloneUI-CF-DU1-adt-k-11-0-UI 3′, mRNA sequence [BM979607] A_24_P417922A_24_P417922 Unknown NM_000997 RPL37 Homo sapiens ribosomal protein L37(RPL37), mRNA [NM_000997] THC2755576 THC2755576 ALU1_HUMAN (P39188) Alusubfamily J sequence contamination warning entry, partial (13%)[THC2755576] NM_152789 FAM133B Homo sapiens hypothetical proteinMGC40405 (MGC40405), transcript variant 1, mRNA [NM_152789] NM_000336SCNN1B Homo sapiens sodium channel, nonvoltage-gated 1, beta (Liddlesyndrome) (SCNN1B), mRNA [NM_000336] NM_000986 RPL24 Homo sapiensribosomal protein L24 (RPL24), mRNA [NM_000986] NM_000633 BCL2 Homosapiens B-cell CLL/lymphoma 2 (BCL2), nuclear gene encodingmitochondrial protein, transcript variant alpha, mRNA [NM_000633]THC2679528 THC2679528 Unknown BX090181 BX090181 BX090181 NCI_CGAP_Lu5Homo sapiens cDNA clone IMAGp998M204062; IMAGE: 1602235, mRNA sequence[BX090181] NM_001214 C16orf3 Homo sapiens chromosome 16 open readingframe 3 (C16orf3), mRNA [NM_001214] AF113008 AF113008 Homo sapiens cloneFLB0708 mRNA sequence. [AF113008] NM_014625 NPHS2 Homo sapiens nephrosis2, idiopathic, steroid-resistant (podocin) (NPHS2), mRNA [NM_014625]A_24_P366457 A_24_P366457 Unknown NM_014189 ADD1 Homo sapiens adducin 1(alpha) (ADD1), transcript variant 2, mRNA [NM_014189] AK092748RP3-377H14.5 Homo sapiens cDNA FL135429 fis, clone SMINT2002126.[AK092748] NM_021046 KRTAP5-8 Homo sapiens keratin associated protein5-8 (KRTAP5-8), mRNA [NM_021046] NM_145019 FAM124A Homo sapiens familywith sequence similarity 124A (FAM124A), mRNA [NM_145019] NM_033318C22orf32 Homo sapiens chromosome 22 open reading frame 32 (C22orf32),mRNA [NM_033318] A_24_P144275 A_24_P144275 Unknown NM_002490 NDUFA6 Homosapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14 kDa(NDUFA6), nuclear gene encoding mitochondrial protein, mRNA [NM_002490]AK090412 LOC375010 Homo sapiens mRNA for FLJ00310 protein. [AK090412]AK124946 DPF3 Homo sapiens cDNA FLJ42956 fis, clone BRSTN2009899.[AK124946] ENST00000337102 ENST00000337102 40S ribosomal protein S21.[Source: Uniprot/SWISSPROT; Acc: P63220] [ENST00000337102] NM_001861COX4I1 Homo sapiens cytochrome c oxidase subunit IV isoform 1 (COX4I1),mRNA [NM_001861] NM_207121 FAM110A Homo sapiens family with sequencesimilarity 110, member A (FAM110A), transcript variant 2, mRNA[NM_207121] NM_145308 C11orf76 Homo sapiens chromosome 11 open readingframe 76 (C11orf76), mRNA [NM_145308] NM_014417 BBC3 Homo sapiens BCL2binding component 3 (BBC3), mRNA [NM_014417] NM_001012 RPS8 Homo sapiensribosomal protein S8 (RPS8), mRNA [NM_001012] NM_181698 CCNY Homosapiens cyclin Y (CCNY), transcript variant 2, mRNA [NM_181698]A_24_P629163 A_24_P629163 Unknown AL137354 AL137354 Homo sapiens mRNA;cDNA DKFZp434A0326 (from clone DKFZp434A0326). [AL137354] NM_001011 RPS7Homo sapiens ribosomal protein S7 (RPS7), mRNA [NM_001011]ENST00000341376 NFYA Nuclear transcription factor Y subunit alpha(Nuclear transcription factor Y subunit A) (NF-YA) (CAAT-box DNA-bindingprotein subunit A). [Source: Uniprot/SWISSPROT; Acc: P23511][ENST00000341376] NM_001025295 IFITM5 Homo sapiens interferon inducedtransmembrane protein 5 (IFITM5), mRNA [NM_001025295] A_24_P730256A_24_P730256 Unknown NM_021640 C12orf10 Homo sapiens chromosome 12 openreading frame 10 (C12orf10), mRNA [NM_021640] NM_199249 C19orf48 Homosapiens chromosome 19 open reading frame 48 (C19orf48), mRNA [NM_199249]XR_018695 RPL31P10 PREDICTED: Homo sapiens similar to ribosomal proteinL31 (LOC390283), mRNA [XR_018695] A_24_P118874 A_24_P118874 UnknownXR_017377 LOC647094 PREDICTED: Homo sapiens similar to acidic ribosomalphosphoprotein P0 (LOC647094), mRNA [XR_017377] NM_001778 CD48 Homosapiens CD48 molecule (CD48), mRNA [NM_001778] NM_000967 RPL3 Homosapiens ribosomal protein L3 (RPL3), transcript variant 1, mRNA[NM_000967] NM_000610 CD44 Homo sapiens CD44 molecule (Indian bloodgroup) (CD44), transcript variant 1, mRNA [NM_000610] NM_001006 RPS3AHomo sapiens ribosomal protein S3A (RPS3A), mRNA [NM_001006] NM_178428LCE2A Homo sapiens late cornified envelope 2A (LCE2A), mRNA [NM_178428]NM_144601 CMTM3 Homo sapiens CKLF-like MARVEL transmembrane domaincontaining 3 (CMTM3), transcript variant 1, mRNA [NM_144601] NM_198969AES Homo sapiens amino-terminal enhancer of split (AES), transcriptvariant 1, mRNA [NM_198969] NM_016404 HSPC152 Homo sapiens hypotheticalprotein HSPC152 (HSPC152), mRNA [NM_016404] NM_021978 ST14 Homo sapienssuppression of tumorigenicity 14 (colon carcinoma) (ST14), mRNA[NM_021978] A_24_P921980 A_24_P921980 Unknown ENST00000310218ENST00000310218 PREDICTED: Homo sapiens similar to large subunitribosomal protein L36a (LOC729621), mRNA [XM_001133900] NM_001082575HRNBP3 Homo sapiens hypothetical protein LOC146713 (HRNBP3), mRNA[NM_001082575] XR_018803 LOC649915 PREDICTED: Homo sapiens similar toGlyceraldehyde-3- phosphate dehydrogenase (GAPDH) (LOC649915), mRNA[XR_018803] NM_001019 RPS15A Homo sapiens ribosomal protein S15a(RPS15A), transcript variant 2, mRNA [NM_001019] NM_016091 EIF3S6IP Homosapiens eukaryotic translation initiation factor 3, subunit 6interacting protein (EIF3S6IP), mRNA [NM_016091] NM_080614 WFDC3 Homosapiens WAP four-disulfide core domain 3 (WFDC3), mRNA [NM_080614]NM_001989 EVX1 Homo sapiens even-skipped homeobox 1 (EVX1), mRNA[NM_001989] BC039555 SNHG8 Homo sapiens cDNA clone IMAGE: 4184613,partial cds. [BC039555] NM_032378 EEF1D Homo sapiens eukaryotictranslation elongation factor 1 delta (guanine nucleotide exchangeprotein) (EEF1D), transcript variant 1, mRNA [NM_032378] NM_025207 FLAD1Homo sapiens FAD1 flavin adenine dinucleotide synthetase homolog (S.cerevisiae) (FLAD1), transcript variant 1, mRNA [NM_025207] NR_001564XIST Homo sapiens X (inactive)-specific transcript (XIST) on chromosomeX [NR_001564] NM_001031 RPS28 Homo sapiens ribosomal protein S28(RPS28), mRNA [NM_001031] XR_016930 LOC645412 PREDICTED: Homo sapienssimilar to 40S ribosomal protein S16 (LOC645412), mRNA [XR_016930]BC107865 LOC204010 Homo sapiens similar to 40S ribosomal protein SA(P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-bindingprotein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1- Ag),mRNA (cDNA clone MGC: 104447 IMAGE: 4095371), complete cds...A_32_P235293 A_32_P235293 Unknown BC040156 LOC284570 Homo sapiens, cloneIMAGE: 4941949, mRNA. [BC040156] A_24_P204454 A_24_P204454 UnknownNM_014507 MCAT Homo sapiens malonyl CoA:ACP acyltransferase(mitochondrial) (MCAT), nuclear gene encoding mitochondrial protein,transcript variant 2, mRNA [NM_014507] XR_015767 LOC731224 PREDICTED:Homo sapiens similar to 60S ribosomal protein L9 (LOC731224), mRNA[XR_015767] A_32_P760762 A_32_P760762 Unknown NM_012266 DNAJB5 Homosapiens DnaJ (Hsp40) homolog, subfamily B, member 5 (DNAJB5), mRNA[NM_012266] NM_001088 AANAT Homo sapiens arylalkylamineN-acetyltransferase (AANAT), mRNA [NM_001088] A_24_P229438 A_24_P229438Unknown NM_000980 RPL18A Homo sapiens ribosomal protein L18a (RPL18A),mRNA [NM_000980] A_24_P533990 A_24_P533990 Unknown BX648200 BX648200Homo sapiens mRNA; cDNA DKFZp779C0742 (from clone DKFZp779C0742).[BX648200] XR_018411 LOC390993 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7a (LOC390993), mRNA [XR_018411] NM_001402 EEF1A1Homo sapiens eukaryotic translation elongation factor 1 alpha 1(EEF1A1), mRNA [NM_001402] A_24_P375932 A_24_P375932 UnknownENST00000247761 ENST00000247761 Unknown NM_054023 SCGB3A2 Homo sapienssecretoglobin, family 3A, member 2 (SCGB3A2), mRNA [NM_054023]NM_001078171 FAM127A Homo sapiens family with sequence similarity 127,member A (FAM127A), mRNA [NM_001078171] NM_182513 SPC24 Homo sapiensSPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)(SPC24), mRNA [NM_182513] NM_024407 NDUFS7 Homo sapiens NADHdehydrogenase (ubiquinone) Fe—S protein 7, 20 kDa (NADH-coenzyme Qreductase) (NDUFS7), mRNA [NM_024407] BC009038 BC009038 Homo sapiens,clone IMAGE: 4179482, mRNA. [BC009038] ENST00000240349 NACA3P PREDICTED:Homo sapiens similar to nascent polypeptide- associated complex alphapolypeptide (LOC389240), mRNA [XM_371715] THC2518594 THC2518594Q6PJD4_HUMAN (Q6PJD4) LOC389906 protein (Fragment), partial (10%)[THC2518594] NM_007286 SYNPO Homo sapiens synaptopodin (SYNPO), mRNA[NM_007286] NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein(MGC70863), transcript variant 1, mRNA [NM_203477] NM_173502 PRSS36 Homosapiens protease, serine, 36 (PRSS36), mRNA [NM_173502] NM_053274 GLMNHomo sapiens glomulin, FKBP associated protein (GLMN), mRNA [NM_053274]NM_203495 COMMD6 Homo sapiens COMM domain containing 6 (COMMD6),transcript variant 2, mRNA [NM_203495] BC047708 BC047708 Homo sapiens,clone IMAGE: 5750141, mRNA. [BC047708] NM_003202 TCF7 Homo sapienstranscription factor 7 (T-cell specific, HMG-box) (TCF7), transcriptvariant 1, mRNA [NM_003202] NM_001688 ATP5F1 Homo sapiens ATP synthase,H+ transporting, mitochondrial F0 complex, subunit B1 (ATP5F1), nucleargene encoding mitochondrial protein, mRNA [NM_001688] NM_194248 OTOFHomo sapiens otoferlin (OTOF), transcript variant 1, mRNA [NM_194248]A_23_P210285 A_23_P210285 Unknown NM_000610 CD44 Homo sapiens CD44molecule (Indian blood group) (CD44), transcript variant 1, mRNA[NM_000610] A_24_P136011 A_24_P136011 Unknown L10123 SPAR Homo sapienssurfactant protein A mRNA, complete cds. [L10123] BC028232 BC028232 Homosapiens, clone IMAGE: 5221276, mRNA, partial cds. [BC028232] NM_007311TSPO Homo sapiens translocator protein (18 kDa) (TSPO), transcriptvariant PBR-S, mRNA [NM_007311] NM_001020 RPS16 Homo sapiens ribosomalprotein S16 (RPS16), mRNA [NM_001020] A_24_P93052 A_24_P93052 UnknownNM_014567 BCAR1 Homo sapiens breast cancer anti-estrogen resistance 1(BCAR1), mRNA [NM_014567] NM_014272 ADAMTS7 Homo sapiens ADAMmetallopeptidase with thrombospondin type 1 motif, 7 (ADAMTS7), mRNA[NM_014272] XR_018303 LOC648378 PREDICTED: Homo sapiens similar toribosomal protein S14 (LOC648378), mRNA [XR_018303] NM_175738 RAB37 Homosapiens RAB37, member RAS oncogene family (RAB37), transcript variant 3,mRNA [NM_175738] NM_001005472 LOC388524 Homo sapiens similar to Lamininreceptor 1 (LOC388524), mRNA [NM_001005472] A_24_P145787 A_24_P145787Unknown BC035978 ATP6V1B1 Homo sapiens ATPase, H+ transporting,lysosomal 56/58 kDa, VI subunit B1 (Renal tubular acidosis withdeafness), mRNA (cDNA clone MGC: 32642 IMAGE: 4594171), complete cds.[BC035978] A_24_P135771 A_24_P135771 Unknown NM_002954 RPS27A Homosapiens ribosomal protein S27a (RPS27A), mRNA [NM_002954] NM_001045548LOC441743 Homo sapiens similar to C367G8.3 (novel protein similar toRPL23A (60S ribosomal protein L23A)) (LOC441743), mRNA [NM_001045548]NM_013279 C11orf9 Homo sapiens chromosome 11 open reading frame 9(C11orf9), mRNA [NM_013279] A_24_P7785 A_24_P7785 Unknown BC067830LOC653391 Homo sapiens similar to hypothetical protein LOC153561, mRNA(cDNA clone MGC: 87375 IMAGE: 5299741), complete cds. [BC067830]NM_000980 RPL18A Homo sapiens ribosomal protein L18a (RPL18A), mRNA[NM_000980] BC041959 BC041959 Homo sapiens cDNA clone IMAGE: 5302136.[BC041959] NM_022731 NUCKS1 Homo sapiens nuclear casein kinase andcyclin-dependent kinase substrate 1 (NUCKS1), mRNA [NM_022731]A_24_P724106 A_24_P724106 Unknown NM_001023 RPS20 Homo sapiens ribosomalprotein S20 (RPS20), mRNA [NM_001023] A_24_P229848 A_24_P229848 UnknownNM_012320 LYPLA3 Homo sapiens lysophospholipase 3 (lysosomalphospholipase A2) (LYPLA3), mRNA [NM_012320] NM_001039567 RPS4Y2 Homosapiens ribosomal protein S4, Y-linked 2 (RPS4Y2), mRNA [NM_001039567]A_24_P178784 A_24_P178784 Unknown AK091931 AK091931 Homo sapiens cDNAFLJ34612 fis, clone KIDNE2014170, highly similar to 40S RIBOSOMALPROTEIN S4, X ISOFORM. [AK091931] BC007394 MGC16291 Homo sapienshypothetical protein MGC16291, mRNA (cDNA clone MGC: 16291 IMAGE:3834089), complete cds. [BC007394] NM_003973 RPL14 Homo sapiensribosomal protein L14 (RPL14), transcript variant 2, mRNA [NM_003973]NM_030913 SEMA6C Homo sapiens sema domain, transmembrane domain (TM),and cytoplasmic domain, (semaphorin) 6C (SEMA6C), mRNA [NM_030913]XM_497657 LOC441876 PREDICTED: Homo sapiens similar to 40S ribosomalprotein S16, transcript variant 1 (LOC441876), mRNA [XM_497657] BF149382BF149382 BF149382 28_15 Human Epidermal Keratinocyte SubtractionLibrary-Upregulated Transcripts Homo sapiens cDNA similar to thiosulfatesulfurtransferase (TST), mRNA sequence [BF149382] NM_170683 P2RX2 Homosapiens purinergic receptor P2X, ligand-gated ion channel, 2 (P2RX2),transcript variant 4, mRNA [NM_170683] NM_025228 TRAF3IP3 Homo sapiensTRAF3 interacting protein 3 (TRAF3IP3), mRNA [NM_025228] AK124741AK124741 Homo sapiens cDNA FLJ42751 fis, clone BRAWH3000491, moderatelysimilar to 40S ribosomal protein S12. [AK124741] NM_020212 LOC56964 Homosapiens hypothetical protein from EUROIMAGE 384293 (LOC56964), mRNA[NM_020212] NM_000940 PON3 Homo sapiens paraoxonase 3 (PON3), mRNA[NM_000940] NM_004386 NCAN Homo sapiens neurocan (NCAN), mRNA[NM_004386] NM_001010853 ACY1L2 Homo sapiens aminoacylase 1-like 2(ACY1L2), mRNA [NM_001010853] AK095213 AK095213 Homo sapiens cDNAFLJ37894 fis, clone BRTHA2004639. [AK095213] NM_000985 RPL17 Homosapiens ribosomal protein L17 (RPL17), transcript variant 1, mRNA[NM_000985] THC2666258 THC2666258 P13985_HUMAN (P13985) P25 protein,partial (97%) [THC2666258] BC033528 BC033528 Homo sapiens cDNA cloneIMAGE: 4822684. [BC033528] NM_003724 JRK Homo sapiens jerky homolog(mouse) (JRK), transcript variant 1, mRNA [NM_003724] THC2679528THC2679528 Unknown ENST00000336505 ENST00000336505 Uncharacterizedprotein C9orf126. [Source: Uniprot/SWISSPROT; Acc: Q8N9R8][ENST00000336505] NM_000455 STK11 Homo sapiens serine/threonine kinase11 (STK11), mRNA [NM_000455] ENST00000335083 LOC728449 annexin A8[Source: RefSeq_peptide; Acc: NP_001621] [ENST00000335083] A_24_P298835A_24_P298835 Unknown NM_001006 RPS3A Homo sapiens ribosomal protein S3A(RPS3A), mRNA [NM_001006] NM_019059 TOMM7 Homo sapiens translocase ofouter mitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA [NM_019059]NM_025228 TRAF3IP3 Homo sapiens TRAF3 interacting protein 3 (TRAF3IP3),mRNA [NM_025228] A_24_P685729 A_24_P685729 Unknown XR_018231 LOC648027PREDICTED: Homo sapiens similar to Elongation factor 1-gamma(EF-1-gamma) (eEF-1B gamma) (LOC648027), mRNA [XR_018231] AK096498AK096498 Homo sapiens cDNA FLJ39179 fis, clone OCBBF2004147. [AK096498]XR_017130 LOC158345 PREDICTED: Homo sapiens similar to ribosomal proteinL4 (LOC158345), mRNA [XR_017130] NM_014276 RBPJL Homo sapiensrecombination signal binding protein for immunoglobulin kappa Jregion-like (RBPJL), mRNA [NM_014276] NM_003950 F2RL3 Homo sapienscoagulation factor II (thrombin) receptor-like 3 (F2RL3), mRNA[NM_003950] NM_001907 CTRL Homo sapiens chymotrypsin-like (CTRL), mRNA[NM_001907] NM_001618 PARP1 Homo sapiens poly (ADP-ribose) polymerasefamily, member 1 (PARP1), mRNA [NM_001618] A_24_P24724 A_24_P24724Unknown ENST00000321214 C16orf81 Uncharacterized protein C16orf81.[Source: Uniprot/SPTREMBL; Acc: Q8N9R0] [ENST00000321214] NM_198253 TERTHomo sapiens telomerase reverse transcriptase (TERT), transcript variant1, mRNA [NM_198253] NM_153338 GGT6 Homo sapiensgamma-glutamyltransferase 6 homolog (rat) (GGT6), mRNA [NM_153338]NM_182924 MICALL2 Homo sapiens MICAL-like 2 (MICALL2), transcriptvariant 1, mRNA [NM_182924] NM_174918 C19orf59 Homo sapiens chromosome19 open reading frame 59 (C19orf59), mRNA [NM_174918] NR_002182 NACAP1Homo sapiens nascent-polypeptide-associated complex alpha polypeptidepseudogene 1 (NACAP1) on chromosome 8 [NR_002182] XR_016196 LOC642652PREDICTED: Homo sapiens hypothetical LOC642652 (LOC642652), mRNA[XR_016196] AA807824 AA807824 AA807824 nu96g07.s1 NCI_CGAP_Pr22 Homosapiens cDNA clone IMAGE: 1218588 3′, mRNA sequence [AA807824] NM_053275RPLP0 Homo sapiens ribosomal protein, large, P0 (RPLP0), transcriptvariant 2, mRNA [NM_053275] XM_372331 NKX1-2 PREDICTED: Homo sapiens NK1transcription factor related, locus 2 (Drosophila) (NKX1-2), mRNA[XM_372331] XR_019454 LOC130865 PREDICTED: Homo sapiens similar to 60Sribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)(LOC130865), mRNA [XR_019454] THC2504576 THC2504576 RL26_BOVIN (P61257)60S ribosomal protein L26, complete [THC2504576] A_24_P101694A_24_P101694 Unknown THC2668710 THC2668710 Q8NI81_HUMAN (Q8NI81)OK/SW-CL.41, partial (21%) [THC2668710] NM_001432 EREG Homo sapiensepiregulin (EREG), mRNA [NM_001432] NM_005568 LHX1 Homo sapiens LIMhomeobox 1 (LHX1), mRNA [NM_005568] NM_001153 ANXA4 Homo sapiens annexinA4 (ANXA4), mRNA [NM_001153] A_24_P135242 A_24_P135242 Unknown NM_014351SULT4A1 Homo sapiens sulfotransferase family 4A, member 1 (SULT4A1),mRNA [NM_014351] NM_019064 SDK2 Homo sapiens sidekick homolog 2(chicken) (SDK2), mRNA [NM_019064] NM_032219 MFSD7 Homo sapiens majorfacilitator superfamily domain containing 7 (MFSD7), mRNA [NM_032219]NM_033625 RPL34 Homo sapiens ribosomal protein L34 (RPL34), transcriptvariant 2, mRNA [NM_033625] ENST00000321566 ENST00000321566 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7a, transcript variant 3(LOC388474), mRNA [XM_938181] XM_060535 hCG_1641703 PREDICTED: Homosapiens similar to ribosomal protein L18a (LOC127545), mRNA [XM_060535]ENST00000297544 hCG_1818237 PREDICTED: Homo sapiens similar to 60Sacidic ribosomal protein P1 (LOC133609), mRNA [XM_068430] NR_002797LOC255783 Homo sapiens hypothetical protein LOC255783 (LOC255783) onchromosome 19 [NR_002797] NM_014501 UBE2S Homo sapiensubiquitin-conjugating enzyme E2S (UBE2S), mRNA [NM_014501] NM_145015MRGPRF Homo sapiens MAS-related GPR, member F (MRGPRF), mRNA [NM_145015]XR_019248 LOC130728 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L7 (LOC130728), mRNA [XR_019248] ENST00000356196 hCG_26523PREDICTED: Homo sapiens similar to 60S ribosomal protein L26(LOC646161), mRNA [XR_018048] NM_000955 PTGER1 Homo sapiensprostaglandin E receptor 1 (subtype EP1), 42 kDa (PTGER1), mRNA[NM_000955] ENST00000273844 ENST00000273844 PREDICTED: Homo sapienssimilar to ribosomal protein S15a (LOC391656), mRNA [XM_373027]NM_032087 PCDHGA7 Homo sapiens protocadherin gamma subfamily A, 7(PCDHGA7), transcript variant 2, mRNA [NM_032087] AK092739 MCF2L Homosapiens cDNA FLJ35420 fis, clone SMINT2001183. [AK092739] NM_021008DEAF1 Homo sapiens deformed epidermal autoregulatory factor 1(Drosophila) (DEAF1), mRNA [NM_021008] NM_004420 DUSP8 Homo sapiens dualspecificity phosphatase 8 (DUSP8), mRNA [NM_004420] ENST00000237840hCG_1642354 PREDICTED: Homo sapiens similar to 60S ribosomal proteinL23a (LOC341511), mRNA [XM_292109] THC2722749 THC2722749 Q4RTW1_TETNG(Q4RTW1) Chromosome 12 SCAF14996, whole genome shotgun sequence.(Fragment), partial (77%) [THC2722749] NM_005987 SPRR1A Homo sapienssmall proline-rich protein 1A (SPRR1A), mRNA [NM_005987] AK096241AK096241 Homo sapiens cDNA FLJ38922 fis, clone NT2NE2011691. [AK096241]NM_006506 RASA2 Homo sapiens RAS p21 protein activator 2 (RASA2), mRNA[NM_006506] THC2612025 THC2612025 Q883S2_PSESM (Q883S2) Universal stressprotein family, partial (9%) [THC2612025] A_24_P340886 A_24_P340886Unknown THC2533242 THC2533242 FRG1_HUMAN (Q14331) FRG1 protein (FSHDregion gene 1 protein), partial (21%) [THC2533242] A_24_P367063A_24_P367063 Unknown A_24_P464798 A_24_P464798 Unknown NM_173828 C5orf16Homo sapiens chromosome 5 open reading frame 16 (C5orf16), mRNA[NM_173828] NM_016274 PLEKHO1 Homo sapiens pleckstrin homology domaincontaining, family O member 1 (PLEKHO1), mRNA [NM_016274] AK000420AK000420 Homo sapiens cDNA FLJ20413 fis, clone KAT02170. [AK000420]A_32_P78164 A_32_P78164 Unknown XM_070233 LOC137107 PREDICTED: Homosapiens similar to ribosomal protein L10a (LOC137107), mRNA [XM_070233]NM_000998 RPL37A Homo sapiens ribosomal protein L37a (RPL37A), mRNA[NM_000998] A_24_P169493 A_24_P169493 Unknown NM_007209 RPL35 Homosapiens ribosomal protein L35 (RPL35), mRNA [NM_007209] NM_030966KRTAP1-3 Homo sapiens keratin associated protein 1-3 (KRTAP1-3), mRNA[NM_030966] AA418814 AA418814 AA418814 zw01a02.s1 Soares_NhHMPu_S1 Homosapiens cDNA clone IMAGE: 767978 3′, mRNA sequence [AA418814]ENST00000361461 LOC387867 Homo sapiens cDNA clone IMAGE: 30318308,partial cds. [BC070327] BG036557 BG036557 602326332F1 NIH_MGC_91 Homosapiens cDNA clone IMAGE: 4428126 5′, mRNA sequence [BG036557] BC080624BC080624 Homo sapiens cDNA clone MGC: 99790 IMAGE: 6304510, completecds. [BC080624] AK024362 LOC147650 Homo sapiens cDNA FLJ14300 fis, clonePLACE1011891. [AK024362] XM_928025 LOC644937 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L10 (QM protein) (Tumor suppressor QM)(Laminin receptor homolog) (LOC644937), mRNA [XM_928025] NM_006032 CPNE6Homo sapiens copine VI (neuronal) (CPNE6), mRNA [NM_006032] XR_015402LOC731170 PREDICTED: Homo sapiens similar to eukaryotic translationelongation factor 1 alpha 2 (LOC731170), mRNA [XR_015402] NM_002512 NME2Homo sapiens non-metastatic cells 2, protein (NM23B) expressed in(NME2), transcript variant 1, mRNA [NM_002512] AK074447 FLJ23867 Homosapiens cDNA FLJ23867 fis, clone LNG09729. [AK074447] NM_138693 KLF14Homo sapiens Kruppel-like factor 14 (KLF14), mRNA [NM_138693] NM_033347KCNK7 Homo sapiens potassium channel, subfamily K, member 7 (KCNK7),transcript variant A, mRNA [NM_033347] BG209258 LOC728315 RST28773Athersys RAGE Library Homo sapiens cDNA, mRNA sequence [BG209258]AF111848 AF111848 Homo sapiens PRO0529 mRNA, complete cds. [AF111848]XM_372498 LOC390427 PREDICTED: Homo sapiens similar to TBP-associatedfactor 15 isoform 1 (LOC390427), mRNA [XM_372498] AK025430 AK025430 Homosapiens cDNA: FLJ21777 fis, clone HEP00173. [AK025430] NM_153266 TMEM151Homo sapiens transmembrane protein 151 (TMEM151), mRNA [NM_153266]A_24_P315654 A_24_P315654 Unknown THC2649348 THC2649348 AY491776 alpha1A adrenoceptor isoform 2c {Homo sapiens} (exp = −1; wgp = 0; cg = 0),partial (11%) [THC2649348] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] NM_012183FOXD3 Homo sapiens forkhead box D3 (FOXD3), mRNA [NM_012183]ENST00000273794 LOC90113 Homo sapiens mRNA; cDNA DKFZp761K032 (fromclone DKFZp761K032). [AL834499] NM_007209 RPL35 Homo sapiens ribosomalprotein L35 (RPL35), mRNA [NM_007209] A_24_P307466 A_24_P307466 UnknownTHC2541331 THC2541331 HSU02032 ribosomal protein L23a {Homo sapiens}(exp = −1; wgp = 0; cg = 0), partial (71%) [THC2541331] A_24_P32207A_24_P32207 Unknown A_24_P118382 A_24_P118382 Unknown NM_017805 RASIP1Homo sapiens Ras interacting protein 1 (RASIP1), mRNA [NM_017805]THC2545510 THC2545510 ALU1_HUMAN (P39188) Alu subfamily J sequencecontamination warning entry, partial (13%) [THC2545510] AK131261 TMPRSS9Homo sapiens cDNA FLJ16193 fis, clone BRTHA2018011, weakly similar toEPITHIN (EC 3.4.21.—). [AK131261] NM_002823 PTMA Homo sapiensprothymosin, alpha (gene sequence 28) (PTMA), mRNA [NM_002823] BX115782BX115782 BX115782 Soares_testis_NHT Homo sapiens cDNA cloneIMAGp998E224413, mRNA sequence [BX115782] ENST00000380739 SERPINB1Leukocyte elastase inhibitor (LEI) (Serpin B1) (Monocyte/neutrophilelastase inhibitor) (M/NEI) (EI). [Source: Uniprot/SWISSPROT; Acc:P30740] [ENST00000380739] AW269579 AW269579 xv43d08.x1Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE: 2815887 3′ similar togb: Z23090 HEAT SHOCK 27 KD PROTEIN (HUMAN);, mRNA sequence [AW269579]ENST00000323057 ENST00000323057 Uncharacterized protein C1orf46(Skin-specific protein xp33) (Fragment). [Source: Uniprot/SPTREMBL; Acc:O14635] [ENST00000323057] THC2655508 THC2655508 Q4SPR8_TETNG (Q4SPR8)Chromosome 16 SCAF14537, whole genome shotgun sequence. (Fragment),partial (16%) [THC2655508] NM_001014 RPS10 Homo sapiens ribosomalprotein S10 (RPS10), mRNA [NM_001014] NM_003560 PLA2G6 Homo sapiensphospholipase A2, group VI (cytosolic, calcium- independent) (PLA2G6),transcript variant 1, mRNA [NM_003560] THC2704973 THC2704973 UnknownNM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA[NM_000984] NM_003107 SOX4 Homo sapiens SRY (sex determining regionY)-box 4 (SOX4), mRNA [NM_003107] AL080233 AL080233 Homo sapiens mRNA;cDNA DKFZp586L111 (from clone DKFZp586L111). [AL080233] NM_006302 GCS1Homo sapiens glucosidase I (GCS1), mRNA [NM_006302] A_24_P358390A_24_P358390 Unknown NM_020433 JPH2 Homo sapiens junctophilin 2 (JPH2),transcript variant 1, mRNA [NM_020433] NM_006597 HSPA8 Homo sapiens heatshock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597]NM_032792 ZBTB45 Homo sapiens zinc finger and BTB domain containing 45(ZBTB45), mRNA [NM_032792] XR_019376 LOC285260 PREDICTED: Homo sapienssimilar to ribosomal protein L31 (LOC285260), mRNA [XR_019376]A_24_P587803 A_24_P587803 Unknown NM_006235 POU2AF1 Homo sapiens POUdomain, class 2, associating factor 1 (POU2AF1), mRNA [NM_006235]AK095945 AK095945 Homo sapiens cDNA FLJ38626 fis, clone HEART2009599.[AK095945] A_24_P221375 A_24_P221375 Unknown A_24_P341386 A_24_P341386Unknown NM_032378 EEF1D Homo sapiens eukaryotic translation elongationfactor 1 delta (guanine nucleotide exchange protein) (EEF1D), transcriptvariant 1, mRNA [NM_032378] A_24_P358205 A_24_P358205 Unknown NM_194278C14orf43 Homo sapiens chromosome 14 open reading frame 43 (C14orf43),transcript variant 1, mRNA [NM_194278] AF136171 RPL22 Homo sapiensheparin-binding protein HBp15 mRNA, complete cds. [AF136171] NM_033625RPL34 Homo sapiens ribosomal protein L34 (RPL34), transcript variant 2,mRNA [NM_033625] NM_003202 TCF7 Homo sapiens transcription factor 7(T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] NM_178013 PRIMA1 Homo sapiens proline rich membrane anchor 1(PRIMA1), mRNA [NM_178013] A_24_P878388 A_24_P878388 Unknown NM_021025TLX3 Homo sapiens T-cell leukemia homeobox 3 (TLX3), mRNA [NM_021025]A_24_P349489 A_24_P349489 Unknown NM_033260 FOXQ1 Homo sapiens forkheadbox Q1 (FOXQ1), mRNA [NM_033260] NM_025187 C16orf70 Homo sapienschromosome 16 open reading frame 70 (C16orf70), mRNA [NM_025187]NM_018490 LGR4 Homo sapiens leucine-rich repeat-containing Gprotein-coupled receptor 4 (LGR4), mRNA [NM_018490] XR_018554 LOC402219PREDICTED: Homo sapiens similar to ribosomal protein L5 (LOC402219),mRNA [XR_018554] XR_018010 LOC641727 PREDICTED: Homo sapiens similar to60S ribosomal protein L7a (LOC641727), mRNA [XR_018010] NM_002723 PRB4Homo sapiens proline-rich protein BstNI subfamily 4 (PRB4), mRNA[NM_002723] NM_019095 CRLS1 Homo sapiens cardiolipin synthase 1 (CRLS1),mRNA [NM_019095] NM_022558 GH2 Homo sapiens growth hormone 2 (GH2),transcript variant 3, mRNA [NM_022558] XR_018786 LOC649303 PREDICTED:Homo sapiens similar to ribosomal protein S10 (LOC649303), mRNA[XR_018786] NM_005356 LCK Homo sapiens lymphocyte-specific proteintyrosine kinase (LCK), transcript variant 2, mRNA [NM_005356] NM_001006RPS3A Homo sapiens ribosomal protein S3A (RPS3A), mRNA [NM_001006]NM_020932 MAGEE1 Homo sapiens melanoma antigen family E, 1 (MAGEE1),mRNA [NM_020932] NM_024099 C11orf48 Homo sapiens chromosome 11 openreading frame 48 (C11orf48), mRNA [NM_024099] THC2540532 THC2540532Unknown ENST00000372073 TMEM164 Transmembrane protein 164. [Source:Uniprot/SWISSPROT; Acc: Q5U3C3] [ENST00000372073] NM_153813 ZFPM1 Homosapiens zinc finger protein, multitype 1 (ZFPM1), mRNA [NM_153813]NM_006270 RRAS Homo sapiens related RAS viral (r-ras) oncogene homolog(RRAS), mRNA [NM_006270] NM_001006 RPS3A Homo sapiens ribosomal proteinS3A (RPS3A), mRNA [NM_001006] NM_021044 DHH Homo sapiens desert hedgehoghomolog (Drosophila) (DHH), mRNA [NM_021044] BC006438 BC006438 Homosapiens cDNA clone MGC: 13162 IMAGE: 3010103, complete cds. [BC006438]NM_001012361 WDR31 Homo sapiens WD repeat domain 31 (WDR31), transcriptvariant 1, mRNA [NM_001012361] A_24_P32836 A_24_P32836 UnknownA_24_P862251 A_24_P862251 Unknown NM_002823 PTMA Homo sapiensprothymosin, alpha (gene sequence 28) (PTMA), mRNA [NM_002823] NM_022036GPRC5C Homo sapiens G protein-coupled receptor, family C, group 5,member C (GPRC5C), transcript variant 1, mRNA [NM_022036] NM_133328DEDD2 Homo sapiens death effector domain containing 2 (DEDD2), mRNA[NM_133328] NM_005632 SOLH Homo sapiens small optic lobes homolog(Drosophila) (SOLH), mRNA [NM_005632] ENST00000359659 ENST00000359659Q8BT90_MOUSE (Q8BT90) 10, 11 days embryo whole body cDNA, RIKENfull-length enriched library, clone: 2810021H19 product: ribosomalprotein S17, full insert sequence. (Fragment), partial (98%)[THC2555910] A_32_P25809 A_32_P25809 Unknown NM_000041 APOE Homo sapiensapolipoprotein E (APOE), mRNA [NM_000041] AK057177 L3MBTL2 Homo sapienscDNA FLJ32615 fis, clone STOMA2000148. [AK057177] NM_152571 C9orf163Homo sapiens chromosome 9 open reading frame 163 (C9orf163), mRNA[NM_152571] NM_024901 DENND2D Homo sapiens DENN/MADD domain containing2D (DENND2D), mRNA [NM_024901] NM_001021 RPS17 Homo sapiens ribosomalprotein S17 (RPS17), mRNA [NM_001021] NM_005284 GPR6 Homo sapiens Gprotein-coupled receptor 6 (GPR6), mRNA [NM_005284] NM_001042535 CENTG3Homo sapiens centaurin, gamma 3 (CENTG3), transcript variant 2, mRNA[NM_001042535] NM_152243 CDC42EP1 Homo sapiens CDC42 effector protein(Rho GTPase binding) 1 (CDC42EP1), transcript variant 1, mRNA[NM_152243] NM_001009 RPS5 Homo sapiens ribosomal protein S5 (RPS5),mRNA [NM_001009] NM_002801 PSMB10 Homo sapiens proteasome (prosome,macropain) subunit, beta type, 10 (PSMB10), mRNA [NM_002801] AK025353AK025353 Homo sapiens cDNA: FLJ21700 fis, clone COL09849, highly similarto HSU14972 Human ribosomal protein S10 mRNA. [AK025353] AB019568AB019568 Homo sapiens mRNA expressed only in placental villi, cloneSMAP83. [AB019568] NM_006476 ATP5L Homo sapiens ATP synthase, H+transporting, mitochondrial F0 complex, subunit G (ATP5L), nuclear geneencoding mitochondrial protein, mRNA [NM_006476] NM_005586 MDFI Homosapiens MyoD family inhibitor (MDFI), mRNA [NM_005586] AI537201 AI537201AI537201 tp06e06.x1 NCI_CGAP_Gas4 Homo sapiens cDNA clone IMAGE: 21870103′, mRNA sequence [AI537201] NM_021136 RTN1 Homo sapiens reticulon 1(RTN1), transcript variant 1, mRNA [NM_021136] NM_001959 EEF1B2 Homosapiens eukaryotic translation elongation factor 1 beta 2 (EEF1B2),transcript variant 1, mRNA [NM_001959] ENST00000359449 ENST00000359449Sequence 237 from Patent WO0220754. [AX721277] A_24_P745960 A_24_P745960Unknown A_24_P247493 A_24_P247493 Unknown NM_016579 CD320 Homo sapiensCD320 molecule (CD320), mRNA [NM_016579] NM_024933 ANKRD53 Homo sapiensankyrin repeat domain 53 (ANKRD53), mRNA [NM_024933] XM_926013 LOC642398PREDICTED: Homo sapiens hypothetical LOC642398, transcript variant 1(LOC642398), mRNA [XM_926013] AI971459 AI971459 AI971459 wq86e07.x1NCI_CGAP_GC6 Homo sapiens cDNA clone IMAGE: 2478948 3′, mRNA sequence[AI971459] A_24_P752279 A_24_P752279 Unknown NM_001522 GUCY2F Homosapiens guanylate cyclase 2F, retinal (GUCY2F), mRNA [NM_001522]NM_052952 DIRC1 Homo sapiens disrupted in renal carcinoma 1 (DIRC1),mRNA [NM_052952] NM_003202 TCF7 Homo sapiens transcription factor 7(T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] NM_052940 LRRC42 Homo sapiens leucine rich repeat containing42 (LRRC42), mRNA [NM_052940] NM_004265 FADS2 Homo sapiens fatty aciddesaturase 2 (FADS2), mRNA [NM_004265] BC071734 BC071734 Homo sapienscDNA clone MGC: 88072 IMAGE: 5549882, complete cds. [BC071734] NM_002466MYBL2 Homo sapiens v-myb myeloblastosis viral oncogene homolog(avian)-like 2 (MYBL2), mRNA [NM_002466] NM_017645 FAM29A Homo sapiensfamily with sequence similarity 29, member A (FAM29A), mRNA [NM_017645]NM_145273 CD300LG Homo sapiens CD300 molecule-like family member g(CD300LG), mRNA [NM_145273] A_32_P71864 A_32_P71864 Unknown NM_015417C20orf28 Homo sapiens chromosome 20 open reading frame 28 (C20orf28),mRNA [NM_015417] NM_002446 MAP3K10 Homo sapiens mitogen-activatedprotein kinase kinase kinase 10 (MAP3K10), mRNA [NM_002446] A_24_P341176A_24_P341176 Unknown XR_019059 LOC654170 PREDICTED: Homo sapiens similarto 40S ribosomal protein S16 (LOC654170), mRNA [XR_019059] NM_001022RPS19 Homo sapiens ribosomal protein S19 (RPS19), mRNA [NM_001022]NM_001632 ALPP Homo sapiens alkaline phosphatase, placental (Reganisozyme) (ALPP), mRNA [NM_001632] NM_014343 CLDN15 Homo sapiens claudin15 (CLDN15), transcript variant 1, mRNA [NM_014343] A_24_P272735A_24_P272735 Unknown NM_004977 KCNC3 Homo sapiens potassiumvoltage-gated channel, Shaw-related subfamily, member 3 (KCNC3), mRNA[NM_004977] AK074960 AK074960 Homo sapiens cDNA FLJ90479 fis, cloneNT2RP3002836, highly similar to Plexin A2. [AK074960] NM_002081 GPC1Homo sapiens glypican 1 (GPC1), mRNA [NM_002081] AF086468 AF086468 Homosapiens full length insert cDNA clone ZD86H05. [AF086468] XR_015398LOC730747 PREDICTED: Homo sapiens similar to 60S ribosomal protein L14(CAG-ISL 7) (LOC730747), mRNA [XR_015398] ENST00000332804ENST00000332804 PREDICTED: Homo sapiens similar to 60S ribosomal proteinL22 (Heparin-binding protein HBp15) (LOC727747), mRNA [XR_015114]XM_935576 LOC641827 PREDICTED: Homo sapiens similar to eukaryotictranslation elongation factor 1 beta 2 (LOC641827), mRNA [XM_935576]NM_054114 TAGAP Homo sapiens T-cell activation GTPase activating protein(TAGAP), transcript variant 2, mRNA [NM_054114] NM_012423 RPL13A Homosapiens ribosomal protein L13a (RPL13A), mRNA [NM_012423] A_23_P58072A_23_P58072 Unknown BC034005 LOC388494 Homo sapiens hypothetical genesupported by AL365406; BC034005, mRNA (cDNA clone IMAGE: 5276795).[BC034005] NM_000982 RPL21 Homo sapiens ribosomal protein L21 (RPL21),mRNA [NM_000982] THC2611974 THC2611974 AY250221 nogo receptor-like 3{Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial (12%) [THC2611974]NM_002124 HLA-DRB1 Homo sapiens major histocompatibility complex, classII, DR beta 1 (HLA-DRB1), mRNA [NM_002124] NM_153236 GIMAP7 Homo sapiensGTPase, IMAP family member 7 (GIMAP7), mRNA [NM_153236] AK096674AK096674 Homo sapiens cDNA FLJ39355 fis, clone PEBLM2003426. [AK096674]NM_024345 WDR32 Homo sapiens WD repeat domain 32 (WDR32), mRNA[NM_024345] A_24_P384469 A_24_P384469 Unknown NM_058219 EXOSC6 Homosapiens exosome component 6 (EXOSC6), mRNA [NM_058219] NM_032810 ATAD1Homo sapiens ATPase family, AAA domain containing 1 (ATAD1), mRNA[NM_032810] NM_003202 TCF7 Homo sapiens transcription factor 7 (T-cellspecific, HMG-box) (TCF7), transcript variant 1, mRNA [NM_003202]NM_006690 MMP24 Homo sapiens matrix metallopeptidase 24(membrane-inserted) (MMP24), mRNA [NM_006690] NM_006360 PCID1 Homosapiens PCI domain containing 1 (herpesvirus entry mediator) (PCID1),mRNA [NM_006360] NM_138573 NRG4 Homo sapiens neuregulin 4 (NRG4), mRNA[NM_138573] AK056421 TNRC6C Homo sapiens cDNA FLJ31859 fis, cloneNT2RP7001231. [AK056421] NM_000164 GIPR Homo sapiens gastric inhibitorypolypeptide receptor (GIPR), mRNA [NM_000164] XR_015445 LOC730773PREDICTED: Homo sapiens similar to 60S ribosomal protein L7a (Surfeitlocus protein 3) (LOC730773), mRNA [XR_015445] NM_000587 C7 Homo sapienscomplement component 7 (C7), mRNA [NM_000587] A_24_P383934 A_24_P383934Unknown NM_001042413 GLIS3 Homo sapiens GLIS family zinc finger 3(GLIS3), transcript variant 1, mRNA [NM_001042413] XM_931016 LOC388076PREDICTED: Homo sapiens similar to ribosomal protein S8, transcriptvariant 2 (LOC388076), mRNA [XM_931016] NM_001007176 C8orf22 Homosapiens chromosome 8 open reading frame 22 (C8orf22), mRNA[NM_001007176] A_24_P238996 A_24_P238996 Unknown NM_005338 HIP1 Homosapiens huntingtin interacting protein 1 (HIP1), mRNA [NM_005338]NM_014395 DAPP1 Homo sapiens dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1), mRNA [NM_014395] NM_018231 FLJ10815 Homosapiens amino acid transporter (FLJ10815), mRNA [NM_018231] XR_019444LOC122589 PREDICTED: Homo sapiens similar to 60S acidic ribosomalprotein P0 (L10E) (LOC122589), mRNA [XR_019444] NM_001747 CAPG Homosapiens capping protein (actin filament), gelsolin-like (CAPG), mRNA[NM_001747] BC011940 BC011940 Homo sapiens cDNA clone IMAGE: 4329532,partial cds. [BC011940] NM_001798 CDK2 Homo sapiens cyclin-dependentkinase 2 (CDK2), transcript variant 1, mRNA [NM_001798] A_24_P551530A_24_P551530 Unknown NM_000607 ORM1 Homo sapiens orosomucoid 1 (ORM1),mRNA [NM_000607] NM_021130 PPIA Homo sapiens peptidylprolyl isomerase A(cyclophilin A) (PPIA), mRNA [NM_021130] XR_018155 LOC643013 PREDICTED:Homo sapiens similar to laminin receptor 1 (ribosomal protein SA)(LOC643013), mRNA [XR_018155] NM_002973 ATXN2 Homo sapiens ataxin 2(ATXN2), mRNA [NM_002973] NM_012272 PRPF40B Homo sapiens PRP40 pre-mRNAprocessing factor 40 homolog B (S. cerevisiae) (PRPF40B), transcriptvariant 2, mRNA [NM_012272] NM_003456 ZNF205 Homo sapiens zinc fingerprotein 205 (ZNF205), transcript variant 1, mRNA [NM_003456] BC025734BC025734 Homo sapiens, clone IMAGE: 5204729, mRNA. [BC025734] NM_020240CDC42SE2 Homo sapiens CDC42 small effector 2 (CDC42SE2), transcriptvariant 1, mRNA [NM_020240] AB011149 AB011149 Homo sapiens mRNA forKIAA0577 protein, partial cds. [AB011149] NM_005828 WDR68 Homo sapiensWD repeat domain 68 (WDR68), mRNA [NM_005828] NM_004137 KCNMB1 Homosapiens potassium large conductance calcium-activated channel, subfamilyM, beta member 1 (KCNMB1), mRNA [NM_004137] NM_016263 FZR1 Homo sapiensfizzy/cell division cycle 20 related 1 (Drosophila) (FZR1), mRNA[NM_016263] ENST00000383061 ENST00000383061 PREDICTED: Homo sapienssimilar to myosin regulatory light chain-like (LOC442204), mRNA[XM_498088] DQ786228 DQ786228 Homo sapiens clone HLS_IMAGE _1699118 mRNAsequence. [DQ786228] XM_941195 LOC388621 PREDICTED: Homo sapiens similarto ribosomal protein L21 (LOC388621), mRNA [XM_941195] NM_002824 PTMSHomo sapiens parathymosin (PTMS), mRNA [NM_002824] AA725389 AA725389ai17f05.s1 Soares_parathyroid_tumor_NbHPA Homo sapiens cDNA clone1343073 3′ similar to TR: P79324 P79324 RIBOSOMAL PROTEIN L15;, mRNAsequence [AA725389] DW451363 DW451363 HHAGE004093 Human liverregeneration after partial hepatectomy Homo sapiens cDNA, mRNA sequence[DW451363] NM_057088 KRT3 Homo sapiens keratin 3 (KRT3), mRNA[NM_057088] NM_174910 TCTE3 Homo sapienst-complex-associated-testis-expressed 3 (TCTE3), mRNA [NM_174910]BE551270 BE551270 BE551270 7b62a07.x1 NCI_CGAP_Lu24 Homo sapiens cDNAclone IMAGE: 3232788 3′, mRNA sequence [BE551270] NM_002948 RPL15 Homosapiens ribosomal protein L15 (RPL15), mRNA [NM_002948] NM_000610 CD44Homo sapiens CD44 molecule (Indian blood group) (CD44), transcriptvariant 1, mRNA [NM_000610] A_24_P919283 A_24_P919283 Unknown CD174733CD174733 CD174733 AGENCOURT_13961604 NIH_MGC_172 Homo sapiens cDNA 5′,mRNA sequence [CD174733] NM_002341 LTB Homo sapiens lymphotoxin beta(TNF superfamily, member 3) (LTB), transcript variant 1, mRNA[NM_002341] NM_005356 LCK Homo sapiens lymphocyte-specific proteintyrosine kinase (LCK), transcript variant 2, mRNA [NM_005356]A_32_P22679 A_32_P22679 Unknown NM_005309 GPT Homo sapiensglutamic-pyruvate transaminase (alanine aminotransferase) (GPT), mRNA[NM_005309] NM_198904 GABRG2 Homo sapiens gamma-aminobutyric acid (GABA)A receptor, gamma 2 (GABRG2), transcript variant 1, mRNA [NM_198904]NM_015335 THRAP2 Homo sapiens thyroid hormone receptor associatedprotein 2 (THRAP2), mRNA [NM_015335] AK096229 AK096229 Homo sapiens cDNAFLJ38910 fis, clone NT2NE2006813, weakly similar to CELL SURFACEGLYCOPROTEIN 1 PRECURSOR. [AK096229] NM_013373 ZDHHC8 Homo sapiens zincfinger, DHHC-type containing 8 (ZDHHC8), mRNA [NM_013373] XR_018405LOC391655 PREDICTED: Homo sapiens similar to 60S ribosomal protein L17(L23) (LOC391655), mRNA [XR_018405] A_24_P916759 A_24_P916759 UnknownBC016140 MVK Homo sapiens mevalonate kinase (mevalonic aciduria), mRNA(cDNA clone MGC: 9001 IMAGE: 3921543), complete cds. [BC016140] BC105992SYNGR2 Homo sapiens synaptogyrin 2, mRNA (cDNA clone MGC: 102914 IMAGE:4746277), complete cds. [BC105992] NM_001077710 FAM110C Homo sapiensfamily with sequence similarity 110, member C (FAM110C), mRNA[NM_001077710] BC018140 RPS21 Homo sapiens ribosomal protein S21, mRNA(cDNA clone MGC: 9438 IMAGE: 3903320), complete cds. [BC018140] AA627135AA627135 nq71a04.s1 NCI_CGAP_Pr22 Homo sapiens cDNA clone IMAGE: 11577423′ similar to SW: R13A_HUMAN P40429 60S RIBOSOMAL PROTEIN L13A;, mRNAsequence [AA627135] NM_000661 RPL9 Homo sapiens ribosomal protein L9(RPL9), transcript variant 1, mRNA [NM_000661] AB075859 ZNF525 Homosapiens mRNA for KIAA1979 protein. [AB075859] NM_003052 SLC34A1 Homosapiens solute carrier family 34 (sodium phosphate), member 1 (SLC34A1),mRNA [NM_003052] XR_018720 LOC392206 PREDICTED: Homo sapiens similar toribosomal protein L10a (LOC392206), mRNA [XR_018720] NM_138763 BAX Homosapiens BCL2-associated X protein (BAX), transcript variant delta, mRNA[NM_138763] NM_001410 MEGF8 Homo sapiens multiple EGF-like-domains 8(MEGF8), mRNA [NM_001410] NM_014807 TMEM24 Homo sapiens transmembraneprotein 24 (TMEM24), mRNA [NM_014807] NM_001014980 FAM132A Homo sapiensC1q domain containing 2 (C1QDC2), mRNA [NM_001014980] NM_001356 DDX3XHomo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X- linked(DDX3X), mRNA [NM_001356] NM_198149 TMEM58 Homo sapiens transmembraneprotein 58 (TMEM58), mRNA [NM_198149] A_24_P127442 A_24_P127442 UnknownNM_016155 MMP17 Homo sapiens matrix metallopeptidase 17(membrane-inserted) (MMP17), mRNA [NM_016155] U79275 HSU79275 Humanclone 23947 mRNA, partial cds. [U79275] NM_021569 GRIN1 Homo sapiensglutamate receptor, ionotropic, N-methyl D-aspartate 1 (GRIN1),transcript variant NR1-2, mRNA [NM_021569] THC2567891 THC2567891Q6NXR8_HUMAN (Q6NXR8) Ribosomal protein S3a, partial (91%) [THC2567891]NM_003295 TPT1 Homo sapiens tumor protein, translationally-controlled 1(TPT1), mRNA [NM_003295] NM_016428 ABI3 Homo sapiens ABI gene family,member 3 (ABI3), mRNA [NM_016428] AK091355 LOC284926 Homo sapiens cDNAFLJ34036 fis, clone FCBBF2005069. [AK091355] NM_001823 CKB Homo sapienscreatine kinase, brain (CKB), mRNA [NM_001823] THC2655417 THC2655417Q5TDX9_HUMAN (Q5TDX9) OTTHUMP00000030619 (Fragment), complete[THC2655417] ENST00000302096 ENST00000302096 bA299N6.3 (LOC198437), mRNA[Source: RefSeq_dna; Acc: NM_001007125] [ENST00000302096] NM_001958EEF1A2 Homo sapiens eukaryotic translation elongation factor 1 alpha 2(EEF1A2), mRNA [NM_001958] NM_000610 CD44 Homo sapiens CD44 molecule(Indian blood group) (CD44), transcript variant 1, mRNA [NM_000610]ENST00000338509 ENST00000338509 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7a (LOC641727), mRNA [XR_018010] BC060766 SLC2A14Homo sapiens solute carrier family 2 (facilitated glucose transporter),member 14, mRNA (cDNA clone MGC: 71510 IMAGE: 5297510), complete cds.[BC060766] NM_005634 SOX3 Homo sapiens SRY (sex determining regionY)-box 3 (SOX3), mRNA [NM_005634] A_24_P384411 A_24_P384411 UnknownNM_000982 RPL21 Homo sapiens ribosomal protein L21 (RPL21), mRNA[NM_000982] THC2506377 THC2506377 HSU02032 ribosomal protein L23a {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (92%) [THC2506377]NM_001080544 LOC653314 Homo sapiens similar to ribosomal protein L19(LOC653314), mRNA [NM_001080544] NM_003809 TNFSF12 Homo sapiens tumornecrosis factor (ligand) superfamily, member 12 (TNFSF12), mRNA[NM_003809] NM_053275 RPLP0 Homo sapiens ribosomal protein, large, P0(RPLP0), transcript variant 2, mRNA [NM_053275] XR_019597 LOC401863PREDICTED: Homo sapiens similar to ribosomal protein L10a (LOC401863),mRNA [XR_019597] NM_080862 SPSB4 Homo sapiens splA/ryanodine receptordomain and SOCS box containing 4 (SPSB4), mRNA [NM_080862] NM_024324CRELD2 Homo sapiens cysteine-rich with EGF-like domains 2 (CRELD2), mRNA[NM_024324] AA282192 AA282192 AA282192 zs89b10.r1 NCI_CGAP_GCB1 Homosapiens cDNA clone IMAGE: 704635 5′, mRNA sequence [AA282192] NM_182688UBE2G2 Homo sapiens ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog,yeast) (UBE2G2), transcript variant 2, mRNA [NM_182688] NM_001395 DUSP9Homo sapiens dual specificity phosphatase 9 (DUSP9), mRNA [NM_001395]A_24_P547010 A_24_P547010 Unknown ENST00000259289 ENST00000259289Unknown BC067080 FCRLB Homo sapiens Fc receptor-like B, mRNA (cDNA cloneMGC: 71141 IMAGE: 3529386), complete cds. [BC067080] NM_004689 MTA1 Homosapiens metastasis associated 1 (MTA1), mRNA [NM_004689] NM_005250 FOXL1Homo sapiens forkhead box L1 (FOXL1), mRNA [NM_005250] ENST00000355748ENST00000355748 Endogenous retrovirus H D1 leaderregion/integrase-derived ORF1, ORF2, and putative envelope protein(Endogenous retrovirus H protease/integrase-derived ORF1, ORF2, andputative envelope protein). [Source: Uniprot/SPTREMBL; Acc: O00627][ENST00000355748] AK130207 LOC442325 Homo sapiens cDNA FLJ26697 fis,clone PCD00618. [AK130207] NM_138778 WDR85 Homo sapiens WD repeat domain85 (WDR85), mRNA [NM_138778] A_24_P714316 A_24_P714316 Unknown NM_003021SGTA Homo sapiens small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha (SGTA), mRNA [NM_003021] NM_002333 LRP3 Homo sapienslow density lipoprotein receptor-related protein 3 (LRP3), mRNA[NM_002333] NM_001997 FAU Homo sapiens Finkel-Biskis-Reilly murinesarcoma virus (FBR- MuSV) ubiquitously expressed (fox derived);ribosomal protein S30 (FAU), mRNA [NM_001997] NM_020150 SAR1A Homosapiens SAR1 gene homolog A (S. cerevisiae) (SAR1A), mRNA [NM_020150]A_32_P79515 A_32_P79515 Unknown XR_018574 LOC402214 PREDICTED: Homosapiens hypothetical LOC402214 (LOC402214), mRNA [XR_018574] NM_178354LCE1F Homo sapiens late cornified envelope 1F (LCE1F), mRNA [NM_178354]THC2618720 THC2618720 Unknown NM_001728 BSG Homo sapiens basigin (Okblood group) (BSG), transcript variant 1, mRNA [NM_001728] NM_024742ARMC5 Homo sapiens armadillo repeat containing 5 (ARMC5), mRNA[NM_024742] NM_053275 RPLP0 Homo sapiens ribosomal protein, large, P0(RPLP0), transcript variant 2, mRNA [NM_053275] NM_021104 RPL41Homo_sapiens ribosomal protein L41 (RPL41), transcript variant 1, mRNA[NM_021104] XR_019574 LOC400064 PREDICTED: Homo sapiens hypotheticalLOC400064 (LOC400064), mRNA [XR_019574] AL834350 PPP2R5C Homo sapiensmRNA; cDNA DKFZp761H0317 (from clone DKFZp761H0317). [AL834350] BC040412BC040412 Homo sapiens, clone IMAGE: 5184855, mRNA. [BC040412] NM_170746C11orf31 Homo sapiens chromosome 11 open reading frame 31 (C11orf31),mRNA [NM_170746] BC028083 TRBV5-4 Homo sapiens T cell receptor betavariable 5-4, mRNA (cDNA clone MGC: 40031 IMAGE: 5217067), complete cds.[BC028083] NM_000454 SOD1 Homo sapiens superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA [NM_000454]AA484677 AA484677 AA484677 ne64a07.s1 NCI_CGAP_Alv1 Homo sapiens cDNAclone IMAGE: 909012, mRNA sequence [AA484677] NM_001004321 FLJ45445 Homosapiens FLJ45445 protein (FLJ45445), mRNA [NM_001004321] NM_153002GPR156 Homo sapiens G protein-coupled receptor 156 (GPR156), mRNA[NM_153002] NM_019105 TNXB Homo sapiens tenascin XB (TNXB), transcriptvariant XB, mRNA [NM_019105] AK026367 AK026367 Homo sapiens cDNA:FLJ22714 fis, clone HSI13646. [AK026367] NM_000989 RPL30 Homo sapiensribosomal protein L30 (RPL30), mRNA [NM_000989] ENST00000332696ENST00000332696 similar to 60S ribosomal protein L23a (LOC644384), mRNA[Source: RefSeq_dna; Acc: XR_017413] [ENST00000332696] XR_015944LOC731681 PREDICTED: Homo sapiens similar to 60S ribosomal protein L9(LOC731681), mRNA [XR_015944] NM_030649 CENTB5 Homo sapiens centaurin,beta 5 (CENTB5), mRNA [NM_030649] NM_001138 AGRP Homo sapiens agoutirelated protein homolog (mouse) (AGRP), transcript variant 1, mRNA[NM_001138] NM_000991 RPL28 Homo sapiens ribosomal protein L28 (RPL28),mRNA [NM_000991] NM_016423 ZNF219 Homo sapiens zinc finger protein 219(ZNF219), mRNA [NM_016423] A_32_P234913 A_32_P234913 Unknown NM_144779FXYD5 Homo sapiens FXYD domain containing ion transport regulator 5(FXYD5), transcript variant 1, mRNA [NM_144779] XR_019544 LOC652890PREDICTED: Homo sapiens similar to 60S ribosomal protein L7 (LOC652890),mRNA [XR_019544] NM_001000 RPL39 Homo sapiens ribosomal protein L39(RPL39), mRNA [NM_001000] NM_152901 PYDC1 Homo sapiens PYD (pyrindomain) containing 1 (PYDC1), mRNA [NM_152901] NM_002823 PTMA Homosapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA [NM_002823]NM_001006 RPS3A Homo sapiens ribosomal protein S3A (RPS3A), mRNA[NM_001006] ENST00000361800 ENST00000361800 Unknown N47494 N47494 N47494yy90a12.s1 Soares_multiple_sclerosis_2NbHMSP Homo sapiens cDNA cloneIMAGE: 280798 3′ similar to gb: M23115 CALCIUM-TRANSPORTING ATPASESARCOPLASMIC RETICULUM TYPE, SLOW (HUMAN);, mRNA sequence [N47494]NM_016564 CEND1 Homo sapiens cell cycle exit and neuronaldifferentiation 1 (CEND1), mRNA [NM_016564] NM_001077238 SPPL2B Homosapiens signal peptide peptidase-like 2B (SPPL2B), transcript variant 3,mRNA [NM_001077238] XR_018553 LOC648294 PREDICTED: Homo sapienshypothetical LOC648294 (LOC648294), mRNA [XR_018553] AK096778 AK096778Homo sapiens cDNA FLJ39459 fis, clone PROST2011439. [AK096778]A_24_P911837 A_24_P911837 Unknown BQ018742 BQ018742 BQ018742UI-H-DH1-awu-d-06-0-UI.s1 NCI_CGAP_DH1 Homo sapiens cDNA clone IMAGE:5823701 3′, mRNA sequence [BQ018742] NM_020764 CASKIN1 Homo sapiens CASKinteracting protein 1 (CASKIN1), mRNA [NM_020764] THC2550272 THC2550272Unknown NM_032848 C12orf52 Homo sapiens chromosome 12 open reading frame52 (C12orf52), mRNA [NM_032848] ENST00000302932 ENST00000302932Uncharacterized protein C20orf181 (Fragment). [Source: Uniprot/SPTREMBL;Acc: Q92884] [ENST00000302932] A_24_P912856 A_24_P912856 UnknownTHC2700213 THC2700213 Q5VZP2_HUMAN (Q5VZP2) HERV-H LTR-associating 3,partial (21%) [THC2700213] NM_053275 RPLP0 Homo sapiens ribosomalprotein, large, P0 (RPLP0), transcript variant 2, mRNA [NM_053275]CN304251 CN304251 17000532640995 GRN_ES Homo sapiens cDNA 5′, mRNAsequence [CN304251] NM_000545 TCF1 Homo sapiens transcription factor 1,hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor(TCF1), mRNA [NM_000545] XM_929928 LOC646960 PREDICTED: Homo sapienssimilar to transmembrane protease, serine 9 (LOC646960), mRNA[XM_929928] AW204925 AW204925 UI-H-BI1-aer-a-07-0-UI.s1 NCI_CGAP_Sub3Homo sapiens cDNA clone IMAGE: 2720149 3′, mRNA sequence [AW204925]NM_002258 KLRB1 Homo sapiens killer cell lectin-like receptor subfamilyB, member 1 (KLRB1), mRNA [NM_002258] NM_031313 ALPPL2 Homo sapiensalkaline phosphatase, placental-like 2 (ALPPL2), mRNA [NM_031313]AK090467 LOC284542 Homo sapiens mRNA for FLJ00388 protein. [AK090467]NM_031478 FAM57B Homo sapiens family with sequence similarity 57, memberB (FAM57B), mRNA [NM_031478] A_24_P238427 A_24_P238427 Unknown NM_022465IKZF4 Homo sapiens IKAROS family zinc finger 4 (Eos) (IKZF4), mRNA[NM_022465] NM_001416 EIF4A1 Homo sapiens eukaryotic translationinitiation factor 4A, isoform 1 (EIF4A1), mRNA [NM_001416] NM_000971RPL7 Homo sapiens ribosomal protein L7 (RPL7), mRNA [NM_000971]NR_002797 LOC255783 Homo sapiens hypothetical protein LOC255783(LOC255783) on chromosome 19 [NR_002797] NM_001078172 FAM127B Homosapiens family with sequence similarity 127, member B (FAM127B), mRNA[NM_001078172] BM680083 BM680083 BM680083 UI-E-EO1-aix-j-14-0-UI.s1UI-E-EO1 Homo sapiens cDNA clone UI-E-EO1-aix-j-14-0-UI 3′, mRNAsequence [BM680083] ENST00000357697 ENST00000357697 Unknown NM_021149COTL1 Homo sapiens coactosin-like 1 (Dictyostelium) (COTL1), mRNA[NM_021149] A_24_P689119 A_24_P689119 Unknown NM_007104 RPL10A Homosapiens ribosomal protein L10a (RPL10A), mRNA [NM_007104] CA455253LOC341412 AGENCOURT_10640955 NIH_MGC_126 Homo sapiens cDNA clone IMAGE:6723568 5′, mRNA sequence [CA455253] NM_000972 RPL7A Homo sapiensribosomal protein L7a (RPL7A), mRNA [NM_000972] XR_018444 LOC643981PREDICTED: Homo sapiens similar to 40S ribosomal protein S3a (V-fostransformation effector protein) (LOC643981), mRNA [XR_018444] XR_015583LOC731731 PREDICTED: Homo sapiens similar to Nucleosome assembly protein1-like 1 (NAP-1-related protein) (hNRP) (LOC731731), mRNA [XR_015583]XR_018808 LOC441641 PREDICTED: Homo sapiens similar to ribosomal proteinL13A (LOC441641), mRNA [XR_018808] NM_015853 LOC51035 Homo sapiens SAPKsubstrate protein 1 (LOC51035), mRNA [NM_015853] ENST00000330598ENST00000330598 Homo sapiens HSPC088 mRNA, partial cds. [AF161351]BC036762 MGC46336 Homo sapiens hypothetical protein MGC46336, mRNA (cDNAclone MGC: 46336 IMAGE: 5588928), complete cds. [BC036762] NM_00664009-Sep Homo sapiens septin 9 (SEPT9), mRNA [NM_006640] NM_001748 CAPN2Homo sapiens calpain 2, (m/II) large subunit (CAPN2), mRNA [NM_001748]NM_017622 C17orf59 Homo sapiens chromosome 17 open reading frame 59(C17orf59), mRNA [NM_017622] NM_017489 TERF1 Homo sapiens telomericrepeat binding factor (NIMA-interacting) 1 (TERF1), transcript variant1, mRNA [NM_017489] NM_001025 RPS23 Homo sapiens ribosomal protein S23(RPS23), mRNA [NM_001025] ENST00000295549 LOC375295 Homo sapienshypothetical gene supported by BC013438, mRNA (cDNA clone IMAGE:3899073), partial cds. [BC013438] NM_053275 RPLP0 Homo sapiens ribosomalprotein, large, P0 (RPLP0), transcript variant 2, mRNA [NM_053275]NM_015284 KIAA0467 Homo sapiens KIAA0467 (KIAA0467), mRNA [NM_015284]NM_003202 TCF7 Homo sapiens transcription factor 7 (T-cell specific,HMG-box) (TCF7), transcript variant 1, mRNA [NM_003202] NM_013271 PCSK1NHomo sapiens proprotein convertase subtilisin/kexin type 1 inhibitor(PCSK1N), mRNA [NM_013271] NM_024963 FBXL18 Homo sapiens F-box andleucine-rich repeat protein 18 (FBXL18), mRNA [NM_024963] NR_002603LOC440353 Homo sapiens nuclear pore complex interacting proteinpseudogene (LOC440353) on chromosome 16 [NR_002603] XR_019476 LOC391845PREDICTED: Homo sapiens similar to 40S ribosomal protein S15 (RIGprotein) (LOC391845), mRNA [XR_019476] NM_033060 KRTAP4-10 Homo sapienskeratin associated protein 4-10 (KRTAP4-10), mRNA [NM_033060] XR_018303LOC648378 PREDICTED: Homo sapiens similar to ribosomal protein S14(LOC648378), mRNA [XR_018303] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] NM_199185NPM1 Homo sapiens nucleophosmin (nucleolar phosphoprotein B23, numatrin)(NPM1), transcript variant 2, mRNA [NM_199185] AA451906 AA451906AA451906 zx16h04.s1 Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA cloneIMAGE: 786679 3′, mRNA sequence [AA451906] BX096698 BX096698 BX096698Soares breast 2NbHBst Homo sapiens cDNA clone IMAGp998E11242, mRNAsequence [BX096698] NM_033025 SYDE1 Homo sapiens synapse defective 1,Rho GTPase, homolog 1 (C. elegans) (SYDE1), mRNA [NM_033025] NM_033625RPL34 Homo sapiens ribosomal protein L34 (RPL34), transcript variant 2,mRNA [NM_033625] AK093171 AK093171 Homo sapiens cDNA FLJ35852 fis, cloneTESTI2007074. [AK093171] XM_929084 LOC646119 PREDICTED: Homo sapienssimilar to ribosomal protein S8 (LOC646119), mRNA [XM_929084] THC2658813THC2658813 Unknown AK128457 AK128457 Homo sapiens cDNA FLJ46600 fis,clone THYMU3047144. [AK128457] NM_032378 EEF1D Homo sapiens eukaryotictranslation elongation factor 1 delta (guanine nucleotide exchangeprotein) (EEF1D), transcript variant 1, mRNA [NM_032378] ENST00000331096ENST00000331096 Unknown NM_021170 HES4 Homo sapiens hairy and enhancerof split 4 (Drosophila) (HES4), mRNA [NM_021170] BC037255 LOC389634 Homosapiens hypothetical LOC389634, mRNA (cDNA clone IMAGE: 4157715).[BC037255] NM_003018 SFTPC Homo sapiens surfactant, pulmonary-associatedprotein C (SFTPC), mRNA [NM_003018] XR_019634 LOC402069 PREDICTED: Homosapiens similar to 40S ribosomal protein S16 (LOC402069), mRNA[XR_019634] CV575560 CV575560 oe37f10.y1 Human keratoconus cornea,unamplified, (od [CV575560] XR_018510 LOC650650 PREDICTED: Homo sapienssimilar to ribosomal protein S5 (LOC650650), mRNA [XR_018510] BF822111BF822111 BF822111 CM3-RT0011-051200-531-f10 RT0011 Homo sapiens cDNA,mRNA sequence [BF822111] NM_022139 GFRA4 Homo sapiens GDNF familyreceptor alpha 4 (GFRA4), transcript variant 1, mRNA [NM_022139]NM_003689 AKR7A2 Homo sapiens aldo-keto reductase family 7, member A2(aflatoxin aldehyde reductase) (AKR7A2), mRNA [NM_003689] NM_002823 PTMAHomo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA[NM_002823] NM_004964 HDAC1 Homo sapiens histone deacetylase 1 (HDAC1),mRNA [NM_004964] NM_053275 RPLP0 Homo sapiens ribosomal protein, large,P0 (RPLP0), transcript variant 2, mRNA [NM_053275] AL133632 AL133632PREDICTED: Homo sapiens hypothetical LOC648245 (LOC648245), mRNA[XM_001127731] NM_004907 IER2 Homo sapiens immediate early response 2(IER2), mRNA [NM_004907] BC018086 MGC13017 Homo sapiens similar to RIKENcDNA A430101B06 gene, mRNA (cDNA clone MGC: 27045 IMAGE: 4793897),complete cds. [BC018086] NM_006985 NPIP Homo sapiens nuclear porecomplex interacting protein (NPIP), mRNA [NM_006985] ENST00000248668LRFN1 Leucine-rich repeat and fibronectin type III domain-containingprotein 1 (Fragment). [Source: Uniprot/SPTREMBL; Acc: Q9P244][ENST00000248668] NM_178128 FADS6 Homo sapiens fatty acid desaturasedomain family, member 6 (FADS6), mRNA [NM_178128] A_24_P170147A_24_P170147 Unknown NM_152219 GJC1 Homo sapiens gap junction protein,chi 1, 31.9 kDa (GJC1), mRNA [NM_152219] NM_000982 RPL21 Homo sapiensribosomal protein L21 (RPL21), mRNA [NM_000982] A_24_P264549A_24_P264549 Unknown NM_006013 RPL10 Homo sapiens ribosomal protein L10(RPL10), mRNA [NM_006013] NM_000985 RPL17 Homo sapiens ribosomal proteinL17 (RPL17), transcript variant 1, mRNA [NM_000985] A_24_P789842A_24_P789842 Unknown NM_003726 SKAP1 Homo sapiens src kinase associatedphosphoprotein 1 (SKAP1), transcript variant 1, mRNA [NM_003726]NM_003961 RHBDL1 Homo sapiens rhomboid, veinlet-like 1 (Drosophila)(RHBDL1), mRNA [NM_003961] XR_019079 LOC651591 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L7a (LOC651591), mRNA [XR_019079]AK055960 AK055960 Homo sapiens cDNA FLJ31398 fis, clone NT2NE1000175.[AK055960] XR_015663 LOC731113 PREDICTED: Homo sapiens hypotheticalprotein LOC731113 (LOC731113), mRNA [XR_015663] NM_005356 LCK Homosapiens lymphocyte-specific protein tyrosine kinase (LCK), transcriptvariant 2, mRNA [NM_005356] NM_001011 RPS7 Homo sapiens ribosomalprotein S7 (RPS7), mRNA [NM_001011] XR_019361 LOC442260 PREDICTED: Homosapiens similar to 60S ribosomal protein L23a (LOC442260), mRNA[XR_019361] AK027315 AK027315 Homo sapiens cDNA FLJ14409 fis, cloneHEMBA1004408, moderately similar to PEPTIDYL-PROLYL CIS-TRANS ISOMERASE10 (EC 5.2.1.8). [AK027315] XR_017247 LOC401975 PREDICTED: Homo sapienssimilar to ribosomal protein S3a (LOC401975), mRNA [XR_017247] AK130118AK130118 Homo sapiens cDNA FLJ26608 fis, clone LVR00914. [AK130118]NM_145808 MTPN Homo sapiens myotrophin (MTPN), mRNA [NM_145808]NM_003295 TPT1 Homo sapiens tumor protein, translationally-controlled 1(TPT1), mRNA [NM_003295] NM_000972 RPL7A Homo sapiens ribosomal proteinL7a (RPL7A), mRNA [NM_000972] A_32_P15169 A_32_P15169 UnknownENST00000308989 ENST00000308989 PREDICTED: Homo sapiens similar toribosomal protein L31 (LOC729005), mRNA [XM_001133428] NM_015023 WDTC1Homo sapiens WD and tetratricopeptide repeats 1 (WDTC1), mRNA[NM_015023] NM_203451 LOC400120 Homo sapiens hypothetical LOC400120(LOC400120), mRNA [NM_203451] THC2672892 THC2672892 Q2TXF9_ASPOR(Q2TXF9) Predicted protein, partial (5%) [THC2672892] XR_019472LOC652328 PREDICTED: Homo sapiens similar to ribosomal protein L21(LOC652328), mRNA [XR_019472] NM_006263 PSME1 Homo sapiens proteasome(prosome, macropain) activator subunit 1 (PA28 alpha) (PSME1),transcript variant 1, mRNA [NM_006263] NM_001014 RPS10 Homo sapiensribosomal protein S10 (RPS10), mRNA [NM_001014] A_24_P186764A_24_P186764 Unknown XR_015936 LOC731457 PREDICTED: Homo sapiens similarto ribosomal protein S27a (LOC731457), mRNA [XR_015936] NM_003202 TCF7Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7),transcript variant 1, mRNA [NM_003202] ENST00000354668 ENST00000354668myelin-associated oligodendrocyte basic protein [Source: RefSeq_peptide;Acc: NP_891980] [ENST00000354668] NM_005247 FGF3 Homo sapiens fibroblastgrowth factor 3 (murine mammary tumor virus integration site (v-int-2)oncogene homolog) (FGF3), mRNA [NM_005247] BC002470 BC002470 Homosapiens mRNA similar to protein kinase, cAMP dependent regulatory, typeI beta (cDNA clone IMAGE: 3349336). [BC002470] NM_001025200 CTRB2 Homosapiens chymotrypsinogen B2 (CTRB2), mRNA [NM_001025200] NM_001152SLC25A5 Homo sapiens solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 5 (SLC25A5), mRNA [NM_001152]NR_002578 GAS5 Homo sapiens growth arrest-specific 5 (GAS5) onchromosome 1 [NR_002578] XR_019529 LOC391595 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L32 (LOC391595), mRNA [XR_019529]NM_003775 EDG6 Homo sapiens endothelial differentiation,lysophosphatidic acid G- protein-coupled receptor, 6 (EDG6), mRNA[NM_003775] NM_004382 CRHR1 Homo sapiens corticotropin releasing hormonereceptor 1 (CRHR1), mRNA [NM_004382] ENST00000323800 ENST00000323800CDNA FLJ25155 fis, clone CBR07976. [Source: Uniprot/SPTREMBL; Acc:Q96LR6] [ENST00000323800] NM_004578 RAB4A Homo sapiens RAB4A, member RASoncogene family (RAB4A), mRNA [NM_004578] NM_006985 NPIP Homo sapiensnuclear pore complex interacting protein (NPIP), mRNA [NM_006985]NM_001666 ARHGAP4 Homo sapiens Rho GTPase activating protein 4(ARHGAP4), mRNA [NM_001666] A_24_P524519 A_24_P524519 Unknown NM_002300LDHB Homo sapiens lactate dehydrogenase B (LDHB), mRNA [NM_002300]NM_000984 RPL23A Homo sapiens ribosomal protein L23a (RPL23A), mRNA[NM_000984] NM_053275 RPLP0 Homo sapiens ribosomal protein, large, P0(RPLP0), transcript variant 2, mRNA [NM_053275] BC033110 HSD17B1 Homosapiens, clone IMAGE: 5443970, mRNA, partial cds. [BC033110] NM_014501UBE2S Homo sapiens ubiquitin-conjugating enzyme E2S (UBE2S), mRNA[NM_014501] NM_152600 ZNF579 Homo sapiens zinc forger protein 579(ZNF579), mRNA [NM_152600] NM_032378 EEF1D Homo sapiens eukaryotictranslation elongation factor 1 delta (guanine nucleotide exchangeprotein) (EEF1D), transcript variant 1, mRNA [NM_032378] A_24_P933372A_24_P933372 Unknown THC2718728 THC2718728 Unknown AK000028 FLJ20021Homo sapiens cDNA FLJ20021 fis, clone ADSE01233. [AK000028] NM_130759GIMAP1 Homo sapiens GTPase, IMAP family member 1 (GIMAP1), mRNA[NM_130759] AK074191 ZNF414 Homo sapiens cDNA FLJ23611 fis, cloneADKA02380. [AK074191] NM_004107 FCGRT Homo sapiens Fc fragment of IgG,receptor, transporter, alpha (FCGRT), mRNA [NM_004107] XR_015600LOC730902 PREDICTED: Homo sapiens similar to 60S ribosomal protein L7(LOC730902), mRNA [XR_015600] XR_019536 LOC401725 PREDICTED: Homosapiens similar to 60S ribosomal protein L6 (TAX-responsive enhancerelement-binding protein 107) (TAXREB107) (Neoplasm-related protein C140)(LOC401725), mRNA [XR_019536] ENST00000307437 ENST00000307437 PREDICTED:Homo sapiens similar to ribosomal protein S12 (LOC727997), mRNA[XM_001127053] XR_017289 LOC643932 PREDICTED: Homo sapiens similar to40S ribosomal protein S3a (V-fos transformation effector protein)(LOC643932), mRNA [XR_017289] XR_018091 LOC646672 PREDICTED: Homosapiens similar to ribosomal protein L15 (LOC646672), mRNA [XR_018091]BC002431 B4GALT2 Homo sapiens cDNA clone IMAGE: 3347310, containingframe- shift errors. [BC002431] NM_033405 PRIC285 Homo sapiensperoxisomal proliferator-activated receptor A interacting complex 285(PRIC285), transcript variant 2, mRNA [NM_033405] NM_014267 C11orf58Homo sapiens chromosome 11 open reading frame 58 (C11orf58), mRNA[NM_014267] NM_003756 EIF3S3 Homo sapiens eukaryotic translationinitiation factor 3, subunit 3 gamma, 40 kDa (EIF3S3), mRNA [NM_003756]NM_000454 SOD1 Homo sapiens superoxide dismutase 1, soluble (amyotrophiclateral sclerosis 1 (adult)) (SOD1), mRNA [NM_000454] BC063531 SIN3BHomo sapiens SIN3 homolog B, transcription regulator (yeast), mRNA (cDNAclone IMAGE: 4417458), complete cds. [BC063531] NM_006122 MAN2A2 Homosapiens mannosidase, alpha, class 2A, member 2 (MAN2A2), mRNA[NM_006122] NM_000454 SOD1 Homo sapiens superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA [NM_000454]NM_000983 RPL22 Homo sapiens ribosomal protein L22 (RPL22), mRNA[NM_000983] NM_024104 C19orf42 Homo sapiens chromosome 19 open readingframe 42 (C19orf42), mRNA [NM_024104] NM_003038 SLC1A4 Homo sapienssolute carrier family 1 (glutamate/neutral amino acid transporter),member 4 (SLC1A4), mRNA [NM_003038] NM_006923 SDF2 Homo sapiens stromalcell-derived factor 2 (SDF2), mRNA [NM_006923] NM_022370 ROBO3 Homosapiens roundabout, axon guidance receptor, homolog 3 (Drosophila)(ROBO3), mRNA [NM_022370] AK023286 FLJ13224 Homo sapiens cDNA FLJ13224fis, clone OVARC1000008. [AK023286] NM_152636 METT5D1 Homo sapiensmethyltransferase 5 domain containing 1 (METT5D1), mRNA [NM_152636]NM_015481 ZNF385 Homo sapiens zinc finger protein 385 (ZNF385), mRNA[NM_015481] AY090769 AY090769 Homo sapiens ribosomal protein S18/S6-likemRNA, complete sequence. [AY090769] NM_001697 ATP5O Homo sapiens ATPsynthase, H+ transporting, mitochondrial F1 complex, O subunit(oligomycin sensitivity conferring protein) (ATP5O), nuclear geneencoding mitochondrial protein, mRNA [NM_001697] NM_147129 ALS2CL Homosapiens ALS2 C-terminal like (ALS2CL), transcript variant 1, mRNA[NM_147129] NM_001402 EEF1A1 Homo sapiens eukaryotic translationelongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402] NM_000982 RPL21Homo sapiens ribosomal protein L21 (RPL21), mRNA [NM_000982] NM_002984CCL4 Homo sapiens chemokine (C-C motif) ligand 4 (CCL4), transcriptvariant 1, mRNA [NM_002984] NM_182796 MAT2B Homo sapiens methionineadenosyltransferase II, beta (MAT2B), transcript variant 2, mRNA[NM_182796] ENST00000359466 ENST00000359466 chromosome X open readingframe 18 (CXorf18), misc RNA [Source: RefSeq_dna; Acc: XR_018001][ENST00000359466] NM_001152 SLC25A5 Homo sapiens solute carrier family25 (mitochondrial carrier; adenine nucleotide translocator), member 5(SLC25A5), mRNA [NM_001152] NM_022551 RPS18 Homo sapiens ribosomalprotein S18 (RPS18), mRNA [NM_022551] N75427 N75427 za82f07.s1Soares_fetal_lung_NbHL19W Homo sapiens cDNA clone IMAGE: 299077 3′similar to gb: X69654 40S RIBOSOMAL PROTEIN S26 (HUMAN);, mRNA sequence[N75427] NM_001867 COX7C Homo sapiens cytochrome c oxidase subunit VIIc(COX7C), nuclear gene encoding mitochondrial protein, mRNA [NM_001867]NM_172138 IL28A Homo sapiens interleukin 28A (interferon, lambda 2)(IL28A), mRNA [NM_172138] NM_053004 GNB1L Homo sapiens guaninenucleotide binding protein (G protein), beta polypeptide 1-like (GNB1L),mRNA [NM_053004] BC034005 LOC388494 Homo sapiens hypothetical genesupported by AL365406; BC034005, mRNA (cDNA clone IMAGE: 5276795).[BC034005] NM_138418 C16orf14 Homo sapiens chromosome 16 open readingframe 14 (C16orf14), mRNA [NM_138418] XM_927514 LOC644357 PREDICTED:Homo sapiens similar to Elongation factor 1-delta (EF-1-delta) (AntigenNY-CO-4) (LOC644357), mRNA [XM_927514] AF007190 AF007190 Homo sapiensSIB 227C intestinal mucin (MUC3) mRNA, partial cds. [AF007190] NM_001030RPS27 Homo sapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27),mRNA [NM_001030] NM_000970 RPL6 Homo sapiens ribosomal protein L6(RPL6), transcript variant 2, mRNA [NM_000970] NM_002818 PSME2 Homosapiens proteasome (prosome, macropain) activator subunit 2 (PA28 beta)(PSME2), mRNA [NM_002818] NM_000992 RPL29 Homo sapiens ribosomal proteinL29 (RPL29), mRNA [NM_000992] AK074162 AK074162 Homo sapiens mRNA forFLJ00235 protein. [AK074162] NM_176812 CHMP4B Homo sapiens chromatinmodifying protein 4B (CHMP4B), mRNA [NM_176812] A_24_P298238A_24_P298238 Unknown NM_003202 TCF7 Homo sapiens transcription factor 7(T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] M74509 M74509 Human endogenous retrovirus type C oncovirussequence. [M74509] NM_139286 CDC26 Homo sapiens cell division cycle 26homolog (S. cerevisiae) (CDC26), mRNA [NM_139286] NM_053025 MYLK Homosapiens myosin, light chain kinase (MYLK), transcript variant 1, mRNA[NM_053025] A_24_P126902 A_24_P126902 Unknown NM_002808 PSMD2 Homosapiens proteasome (prosome, macropain) 26S subunit, non- ATPase, 2(PSMD2), mRNA [NM_002808] A_24_P212654 A_24_P212654 Unknown A_24_P341376A_24_P341376 Unknown THC2579654 THC2579654 Q6P9U5_RAT (Q6P9U5) Ribosomalprotein L9, partial (74%) [THC2579654] NM_145113 MAX Homo sapiens MYCassociated factor X (MAX), transcript variant 3, mRNA [NM_145113]NM_001016 RPS12 Homo sapiens ribosomal protein S12 (RPS12), mRNA[NM_001016] ENST00000389400 ENST00000389400 similar to 40S ribosomalprotein S3a (V-fos transformation effector protein) (LOC391706), mRNA[Source: RefSeq_dna; Acc: XR_017186] [ENST00000389400] XR_018903LOC390612 PREDICTED: Homo sapiens similar to ribosomal protein L18(LOC390612), mRNA [XR_018903] XR_019233 LOC644029 PREDICTED: Homosapiens similar to 60S ribosomal protein L7a (LOC644029), mRNA[XR_019233] A_24_P392436 A_24_P392436 Unknown NM_052896 CSMD2 Homosapiens CUB and Sushi multiple domains 2 (CSMD2), mRNA [NM_052896]NM_145808 MTPN Homo sapiens myotrophin (MTPN), mRNA [NM_145808]NM_000982 RPL21 Homo sapiens ribosomal protein L21 (RPL21), mRNA[NM_000982] NM_007224 NXPH4 Homo sapiens neurexophilin 4 (NXPH4), mRNA[NM_007224] NM_001959 EEF1B2 Homo sapiens eukaryotic translationelongation factor 1 beta 2 (EEF1B2), transcript variant 1, mRNA[NM_001959] XR_018292 LOC392522 PREDICTED: Homo sapiens similar toribosomal protein L18a (LOC392522), mRNA [XR_018292] XM_940966 ASCL5PREDICTED: Homo sapiens similar to Achaete-scute homolog 3 (bHLHtranscriptional regulator Sgn-1) (Mash-3) (LOC647219), mRNA [XM_940966]NM_000997 RPL37 Homo sapiens ribosomal protein L37 (RPL37), mRNA[NM_000997] XR_018339 LOC648448 PREDICTED: Homo sapiens similar toKeratin, type I cytoskeletal 18 (Cytokeratin-18) (CK-18) (Keratin-18)(K18) (LOC648448), mRNA [XR_018339] BC037281 LOC439951 Homo sapienshypothetical LOC439951, mRNA (cDNA clone MGC: 33041 IMAGE: 4838780),complete cds. [BC037281] NM_080621 SAMD10 Homo sapiens sterile alphamotif domain containing 10 (SAMD10), mRNA [NM_080621] NM_033251 RPL13Homo sapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] A_24_P350008 A_24_P350008 Unknown A_24_P745670 A_24_P745670Unknown NM_000982 RPL21 Homo sapiens ribosomal protein L21 (RPL21), mRNA[NM_000982] NM_005626 SFRS4 Homo sapiens splicing factor,arginine/serine-rich 4 (SFRS4), mRNA [NM_005626] NR_002229 RPL23AP13Homo sapiens ribosomal protein L23a pseudogene 13 (RPL23AP13) onchromosome 2 [NR_002229] NM_002954 RPS27A Homo sapiens ribosomal proteinS27a (RPS27A), mRNA [NM_002954] NM_033625 RPL34 Homo sapiens ribosomalprotein L34 (RPL34), transcript variant 2, mRNA [NM_033625] NM_021248CDH22 Homo sapiens cadherin-like 22 (CDH22), mRNA [NM_021248]ENST00000367058 CR2 Complement receptor type 2 precursor (Cr2)(Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor)(CD21 antigen). [Source: Uniprot/SWISSPROT; Acc: P20023][ENST00000367058] A_24_P33213 A_24_P33213 Unknown NM_001767 CD2 Homosapiens CD2 molecule (CD2), mRNA [NM_001767] NM_001014373 C19orf31 Homosapiens chromosome 19 open reading frame 31 (C19orf31), mRNA[NM_001014373] NM_001039842 LOC339229 Homo sapiens hypothetical proteinLOC339229 (LOC339229), mRNA [NM_001039842] NM_012423 RPL13A Homo sapiensribosomal protein L13a (RPL13A), mRNA [NM_012423] XM_496446 LOC440737PREDICTED: Homo sapiens similar to 60S ribosomal protein L35(LOC440737), mRNA [XM_496446] NM_015654 NAT9 Homo sapiensN-acetyltransferase 9 (NAT9), mRNA [NM_015654] A_24_P127621 A_24_P127621Unknown NM_025247 ACAD10 Homo sapiens acyl-Coenzyme A dehydrogenasefamily, member 10 (ACAD10), mRNA [NM_025247] A_23_P329062 A_23_P329062Unknown A_24_P845649 A_24_P845649 Unknown NM_006370 VTI1B Homo sapiensvesicle transport through interaction with t-SNAREs homolog 1B (yeast)(VTI1B), mRNA [NM_006370] A_24_P480722 A_24_P480722 Unknown NM_012086GTF3C3 Homo sapiens general transcription factor IIIC, polypeptide 3,102 kDa (GTF3C3), mRNA [NM_012086] NM_199427 ZFP64 Homo sapiens zincfinger protein 64 homolog (mouse) (ZFP64), transcript variant 4, mRNA[NM_199427] AL117481 DKFZP434B061 Homo sapiens mRNA; cDNA DKFZp434B061(from clone DKFZp434B061); partial cds. [AL117481] NR_001435 HLA-DPB2Homo sapiens major histocompatibility complex, class II, DP beta 2(pseudogene) (HLA-DPB2) on chromosome 6 [NR_001435] NM_018462 C3orf10Homo sapiens chromosome 3 open reading frame 10 (C3orf10), mRNA[NM_018462] THC2494410 THC2494410 2113200F ribosomal protein S9. {Homosapiens} (exp = −1; wgp = −1; cg = −1), complete [THC2494410] NM_005581BCAM Homo sapiens basal cell adhesion molecule (Lutheran blood group)(BCAM), transcript variant 1, mRNA [NM_005581] XR_018133 LOC389404PREDICTED: Homo sapiens similar to 60S ribosomal protein L9 (LOC389404),mRNA [XR_018133] NM_001005862 ERBB2 Homo sapiens v-erb-b2 erythroblasticleukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogenehomolog (avian) (ERBB2), transcript variant 2, mRNA [NM_001005862]AK025669 AK025669 Homo sapiens cDNA: FLJ22016 fis, clone HEP07422.[AK025669] NM_138499 PWWP2 Homo sapiens PWWP domain containing 2(PWWP2), mRNA [NM_138499] NM_001003 RPLP1 Homo sapiens ribosomalprotein, large, P1 (RPLP1), transcript variant 1, mRNA [NM_001003]NM_015893 PRLH Homo sapiens prolactin releasing hormone (PRLH), mRNA[NM_015893] XM_001133211 LOC729003 PREDICTED: Homo sapiens hypotheticalprotein LOC729003 (LOC729003), mRNA [XM_001133211] A_24_P932253A_24_P932253 Unknown NM_000975 RPL11 Homo sapiens ribosomal protein L11(RPL11), mRNA [NM_000975] A_32_P92922 A_32_P92922 Unknown NM_201286USP51 Homo sapiens ubiquitin specific peptidase 51 (USP51), mRNA[NM_201286] NM_002760 PRKY Homo sapiens protein kinase, Y-linked (PRKY),mRNA [NM_002760] XR_018135 LOC390306 PREDICTED: Homo sapienshypothetical LOC390306 (LOC390306), mRNA [XR_018135] NM_006695 RPIP8Homo sapiens RaP2 interacting protein 8 (RPIP8), mRNA [NM_006695]NM_006354 TADA3L Homo sapiens transcriptional adaptor 3 (NGG1 homolog,yeast)- like (TADA3L), transcript variant 1, mRNA [NM_006354] NM_000993RPL31 Homo sapiens ribosomal protein L31 (RPL31), mRNA [NM_000993]NM_206839 MORF4L1 Homo sapiens mortality factor 4 like 1 (MORF4L1),transcript variant 2, mRNA [NM_206839] ENST00000270031 ENST00000270031interferon induced transmembrane protein 3 (1-8U) (IFITM3), mRNA[Source: RefSeq_dna; Acc: NM_021034] [ENST00000270031] NM_003202 TCF7Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7),transcript variant 1, mRNA [NM_003202] XR_019386 LOC652558 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC652558), mRNA[XR_019386] A_24_P807445 A_24_P807445 Unknown A_24_P213073 A_24_P213073Unknown NM_014222 NDUFA8 Homo sapiens NADH dehydrogenase (ubiquinone) 1alpha subcomplex, 8, 19 kDa (NDUFA8), nuclear gene encodingmitochondrial protein, mRNA [NM_014222] NM_002124 HILA-DRB1 Homo sapiensmajor histocompatibility complex, class II, DR beta 1 (HLA-DRB1), mRNA[NM_002124] THC2510656 THC2510656 ALU6_HUMAN (P39193) Alu subfamily SPsequence contamination warning entry, partial (13%) [THC2510656]NM_175734 C17orf74 Homo sapiens chromosome 17 open reading frame 74(C17orf74), mRNA [NM_175734] NM_002273 KRT8 Homo sapiens keratin 8(KRT8), mRNA [NM_002273] NM_021173 POLD4 Homo sapiens polymerase(DNA-directed), delta 4 (POLD4), mRNA [NM_021173] A_32_P185089A_32_P185089 Unknown NM_001005862 ERBB2 Homo sapiens v-erb-b2erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian) (ERBB2), transcript variant 2, mRNA[NM_001005862] A_24_P392195 A_24_P392195 Unknown THC2782843 THC2782843RL18A_HUMAN (Q02543) 60S ribosomal protein L18a, partial (89%)[THC2782843] NM_152889 CHST13 Homo sapiens carbohydrate (chondroitin 4)sulfotransferase 13 (CHST13), mRNA [NM_152889] NM_002855 PVRL1 Homosapiens poliovirus receptor-related 1 (herpesvirus entry mediator C;nectin) (PVRL1), transcript variant 1, mRNA [NM_002855] NM_004852ONECUT2 Homo sapiens one cut domain, family member 2 (ONECUT2), mRNA[NM_004852] NM_003753 EIF3S7 Homo sapiens eukaryotic translationinitiation factor 3, subunit 7 zeta, 66/67 kDa (EIF3S7), mRNA[NM_003753] NM_003636 KCNAB2 Homo sapiens potassium voltage-gatedchannel, shaker-related subfamily, beta member 2 (KCNAB2), transcriptvariant 1, mRNA [NM_003636] NM_001017 RPS13 Homo sapiens ribosomalprotein S13 (RPS13), mRNA [NM_001017] NM_005946 MT1A Homo sapiensmetallothionein 1A (MT1A), mRNA [NM_005946] XR_015591 LOC730861PREDICTED: Homo sapiens similar to 40S ribosomal protein S3a (V-fostransformation effector protein) (LOC730861), mRNA [XR_015591]THC2725746 THC2725746 Unknown NM_014786 ARHGEF17 Homo sapiens Rhoguanine nucleotide exchange factor (GEF) 17 (ARHGEF17), mRNA [NM_014786]NM_001005 RPS3 Homo sapiens ribosomal protein S3 (RPS3), mRNA[NM_001005] NM_001003 RPLP1 Homo sapiens ribosomal protein, large, P1(RPLP1), transcript variant 1, mRNA [NM_001003] NM_000985 RPL17 Homosapiens ribosomal protein L17 (RPL17), transcript variant 1, mRNA[NM_000985] NM_053275 RPLP0 Homo sapiens ribosomal protein, large, P0(RPLP0), transcript variant 2, mRNA [NM_053275] NM_017458 MVP Homosapiens major vault protein (MVP), transcript variant 1, mRNA[NM_017458] NM_019111 HLA-DRA Homo sapiens major histocompatibilitycomplex, class II, DR alpha (HLA-DRA), mRNA [NM_019111] NM_002948 RPL15Homo sapiens ribosomal protein L15 (RPL15), mRNA [NM_002948] THC2515524THC2515524 Unknown NM_001006 RPS3A Homo sapiens ribosomal protein S3A(RPS3A), mRNA [NM_001006] NM_003290 TPM4 Homo sapiens tropomyosin 4(TPM4), mRNA [NM_003290] BC043547 BC043547 Homo sapiens, clone IMAGE:5171873, mRNA. [BC043547] THC2737361 THC2737361 Q2IMJ3_ANADE (Q2IMJ3)LigA, partial (5%) [THC2737361] XR_018509 LOC391701 PREDICTED: Homosapiens similar to ribosomal protein S23 (LOC391701), mRNA [XR_018509]NM_002462 MX1 Homo sapiens myxovirus (influenza virus) resistance 1,interferon- inducible protein p78 (mouse) (MX1), mRNA [NM_002462]NP1252191 NP1252191 GB|AACC02000041.1|EAL24419.1 similar to 60Sribosomal protein L32 [Homo sapiens] [NP1252191] A_24_P118422A_24_P118422 Unknown NM_001080414 KIAA1509 Homo sapiens KIAA1509(KIAA1509), mRNA [NM_001080414] A_24_P41979 A_24_P41979 UnknownNM_033626 CCDC120 Homo sapiens coiled-coil domain containing 120(CCDC120), mRNA [NM_033626] NM_033546 MRLC2 Homo sapiens myosinregulatory light chain MRLC2 (MRLC2), mRNA [NM_033546] NM_213602 CD33L3Homo sapiens CD33 molecule-like 3 (CD33L3), mRNA [NM_213602] AW302767LOC641784 xr55h07.x1 NCI_CGAP_Ov26 Homo sapiens cDNA clone IMAGE:2764093 3′ similar to gb: X69181 60S RIBOSOMAL PROTEIN L31 (HUMAN);,mRNA sequence [AW302767] NM_153822 PSMD4 Homo sapiens proteasome(prosome, macropain) 26S subunit, non- ATPase, 4 (PSMD4), transcriptvariant 2, mRNA [NM_153822] THC2615996 THC2615996 Unknown NM_080660ZC3HAV1L Homo sapiens zinc finger CCCH-type, antiviral 1-like(ZC3HAV1L), mRNA [NM_080660] XR_018524 LOC391560 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L32 (LOC391560), mRNA [XR_018524]NM_203477 MGC70863 Homo sapiens similar to RPL23AP7 protein (MGC70863),transcript variant 1, mRNA [NM_203477] NM_000906 NPR1 Homo sapiensnatriuretic peptide receptor A/guanylate cyclase A (atrionatriureticpeptide receptor A) (NPR1), mRNA [NM_000906] NM_004396 DDX5 Homo sapiensDEAD (Asp-Glu-Ala-Asp) box polypeptide 5 (DDX5), mRNA [NM_004396]NM_203305 FAM102A Homo sapiens family with sequence similarity 102,member A (FAM102A), transcript variant 2, mRNA [NM_203305] NM_020210SEMA4B Homo sapiens sema domain, immunoglobulin domain (Ig),transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B(SEMA4B), transcript variant 1, mRNA [NM_020210] NM_025182 KIAA1539 Homosapiens KIAA1539 (KIAA1539), mRNA [NM_025182] NM_005617 RPS14 Homosapiens ribosomal protein S14 (RPS14), transcript variant 3, mRNA[NM_005617] NM_206908 GUSBL2 Homo sapiens glucuronidase, beta-like 2(GUSBL2), mRNA [NM_206908] A_24_P41250 A_24_P41250 UnknownENST00000078131 ENST00000078131 OTTHUMP00000016594. [Source:Uniprot/SPTREMBL; Acc: Q9NU98] [ENST00000078131] NM_030792 GDPD5 Homosapiens glycerophosphodiester phosphodiesterase domain containing 5(GDPD5), mRNA [NM_030792] XM_930195 hCG_18290 PREDICTED: Homo sapienssimilar to 60S ribosomal protein L32 (LOC644907), mRNA [XM_930195]A_24_P280953 A_24_P280953 Unknown XR_018994 LOC391181 PREDICTED: Homosapiens similar to 60S ribosomal protein L6 (TAX-responsive enhancerelement-binding protein 107) (TAXREB107) (Neoplasm-related protein C140)(LOC391181), mRNA [XR_018994] THC2619175 THC2619175 Q4B270_9BURK(Q4B270) Amidohydrolase 2, partial (6%) [THC2619175] BF969441 BF969441602271732F1 NIH_MGC_84 Homo sapiens cDNA clone IMAGE: 4360158 5′, mRNAsequence [BF969441] NM_016269 LEF1 Homo sapiens lymphoidenhancer-binding factor 1 (LEF1), mRNA [NM_016269] ENST00000246872hCG_1983332 PREDICTED: Homo sapiens similar to 60S ribosomal proteinL35, transcript variant 1 (LOC441246), mRNA [XM_496890] BC054347RP5-860F19.3 Homo sapiens KIAA1442 protein, mRNA (cDNA clone IMAGE:5502800), complete cds. [BC054347] NM_000987 RPL26 Homo sapiensribosomal protein L26 (RPL26), mRNA [NM_000987] XM_926898 LOC643594PREDICTED: Homo sapiens similar to CG13731-PA (LOC643594), mRNA[XM_926898] THC2578835 THC2578835 Unknown NM_001238 CCNE1 Homo sapienscyclin E1 (CCNE1), transcript variant 1, mRNA [NM_001238] BF803942BF803942 BF803942 CM2-C10135-021100-477-g08 CI0135 Homo sapiens cDNA,mRNA sequence [BF803942] AK094477 AK094477 Homo sapiens cDNA FLJ37158fis, clone BRACE2026293. [AK094477] NM_005772 RCL1 Homo sapiens RNAterminal phosphate cyclase-like 1 (RCL1), mRNA [NM_005772] NM_013284POLM Homo sapiens polymerase (DNA directed), mu (POLM), mRNA [NM_013284]XR_018944 LOC442171 PREDICTED: Homo sapiens similar to ribosomal proteinL10 (LOC442171), mRNA [XR_018944] BC011266 C3orf50 Homo sapiens cDNAclone IMAGE: 4156795. [BC011266] NM_138425 C12orf57 Homo sapienschromosome 12 open reading frame 57 (C12orf57), mRNA [NM_138425]ENST00000310344 LOC730647 PREDICTED: Homo sapiens similar to Histidinetriad nucleotide- binding protein 1 (Adenosine 5-monophosphoramidase)(Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1)(PKCI-1) (LOC730647), mRNA [XM_001126674] NM_148887 MRPL10 Homo sapiensmitochondrial ribosomal protein L10 (MRPL10), nuclear gene encodingmitochondrial protein, transcript variant 2, mRNA [NM_148887] NM_199290NACA2 Homo sapiens nascent-polypeptide-associated complex alphapolypeptide-like (NACAL), mRNA [NM_199290] NM_002568 PABPC1 Homo sapienspoly(A) binding protein, cytoplasmic 1 (PABPC1), mRNA [NM_002568]NM_153183 NUDT10 Homo sapiens nudix (nucleoside diphosphate linkedmoiety X)-type motif 10 (NUDT10), mRNA [NM_153183] ENST00000369248KIAA1600 KIAA1600 (KIAA1600), mRNA [Source: RefSeq_dna; Acc: NM_020940][ENST00000369248] NM_021147 CCNU Homo sapiens cyclin U (CCNU), mRNA[NM_021147] NM_024587 TMEM53 Homo sapiens transmembrane protein 53(TMEM53), mRNA [NM_024587] AK098605 AK098605 Homo sapiens cDNA FLJ25739fis, clone TST05834. [AK098605] BC085019 GDF5OS Homo sapienshypothetical LOC554250, mRNA (cDNA clone MGC: 99835 IMAGE: 6650156),complete cds. [BC085019] L79986 SP100 Homo sapiens nuclear autoantigenmRNA, partial cds; alternatively spliced. [L79986] NM_004458 ACSL4 Homosapiens acyl-CoA synthetase long-chain family member 4 (ACSL4),transcript variant 1, mRNA [NM_004458] ENST00000334683 ENST00000334683PREDICTED: Homo sapiens similar to 60S ribosomal protein L17 (L23)(LOC650848), mRNA [XR_019013] THC2714530 THC2714530 Unknown THC2544911THC2544911 MUSEFTU elongation factor Tu {Mus musculus} (exp = −1; wgp =0; cg = 0), partial (37%) [THC2544911] THC2553216 THC2553216 HUMRRL3Aribosomal protein L3 {Homo sapiens} (exp = −1; wgp = 0; cg = 0), partial(24%) [THC2553216] BC063671 LOC92659 Homo sapiens hypothetical proteinBC009233, mRNA (cDNA clone IMAGE: 3924188), partial cds. [BC063671]NM_053275 RPLP0 Homo sapiens ribosomal protein, large, P0 (RPLP0),transcript variant 2, mRNA [NM_053275] NM_001404 EEF1G Homo sapienseukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] NM_014931 SAPS1 Homo sapiens SAPS domain family, member 1(SAPS1), mRNA [NM_014931] NM_005356 LCK Homo sapiens lymphocyte-specificprotein tyrosine kinase (LCK), transcript variant 2, mRNA [NM_005356]NM_005271 GLUD1 Homo sapiens glutamate dehydrogenase 1 (GLUD1), mRNA[NM_005271] XM_001125895 LOC730452 PREDICTED: Homo sapiens similar to60S ribosomal protein L7 (LOC730452), mRNA [XM_001125895] NM_000454 SOD1Homo sapiens superoxide dismutase 1, soluble (amyotrophic lateralsclerosis 1 (adult)) (SOD1), mRNA [NM_000454] NM_133499 SYN1 Homosapiens synapsin I (SYN1), transcript variant Ib, mRNA [NM_133499]AK021957 COL27A1 Homo sapiens cDNA FLJ11895 fis, clone HEMBA1007301,weakly similar to COLLAGEN ALPHA 1(III) CHAIN. [AK021957] XR_016376LOC441073 PREDICTED: Homo sapiens similar to 60S ribosomal protein L26(Silica-induced gene 20 protein) (SIG-20) (LOC441073), mRNA [XR_016376]XR_018530 LOC649178 PREDICTED: Homo sapiens similar to Preli(LOC649178), mRNA [XR_018530] NM_006291 TNFAIP2 Homo sapiens tumornecrosis factor, alpha-induced protein 2 (TNFAIP2), mRNA [NM_006291]THC2654039 THC2654039 ALU2_HUMAN (P39189) Alu subfamily SB sequencecontamination warning entry, partial (4%) [THC2654039] THC2736130THC2736130 Q921R2_MOUSE (Q921R2) Rps13 protein, partial (51%)[THC2736130] NM_001024 RPS21 Homo sapiens ribosomal protein S21 (RPS21),mRNA [NM_001024] A_24_P755505 A_24_P755505 Unknown THC2683228 THC2683228O61351_DROME (O61351) CG12794-PA (La costa), partial (10%) [THC2683228]NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8 (HSPA8),transcript variant 1, mRNA [NM_006597] NM_020358 TRIM49 Homo sapienstripartite motif-containing 49 (TRIM49), mRNA [NM_020358] THC2694215THC2694215 Q3W9Q7_9ACTO (Q3W9Q7) Pyridoxamine 5′-phosphate oxidase,partial (3%) [THC2694215] NM_003184 TAF2 Homo sapiens TAF2 RNApolymerase II, TATA box binding protein (TBP)-associated factor, 150 kDa(TAF2), mRNA [NM_003184] BM351936 BM351936 BM351936 ig84d05.x1 HR85islet Homo sapiens cDNA 3′, mRNA sequence [BM351936] NM_138794 LYPLAL1Homo sapiens lysophospholipase-like 1 (LYPLAL1), mRNA [NM_138794]NM_021959 PPP1R11 Homo sapiens protein phosphatase 1, regulatory(inhibitor) subunit 11 (PPP1R11), mRNA [NM_021959] NM_006522 WNT6 Homosapiens wingless-type MMTV integration site family, member 6 (WNT6),mRNA [NM_006522] XR_019443 LOC442270 PREDICTED: Homo sapiens similar to40S ribosomal protein S12 (LOC442270), mRNA [XR_019443] A_32_P208856A_32_P208856 Unknown A_24_P213375 A_24_P213375 Unknown NM_003222 TFAP2CHomo sapiens transcription factor AP-2 gamma (activating enhancerbinding protein 2 gamma) (TFAP2C), mRNA [NM_003222] NM_021029 RPL36AHomo sapiens ribosomal protein L36a (RPL36A), mRNA [NM_021029] NM_173833SCARA5 Homo sapiens scavenger receptor class A, member 5 (putative)(SCARA5), mRNA [NM_173833] THC2565422 THC2565422 ALU1_HUMAN (P39188) Alusubfamily J sequence contamination warning entry, partial (3%)[THC2565422] NM_152680 TMEM154 Homo sapiens transmembrane protein 154(TMEM154), mRNA [NM_152680] NM_024067 C7orf26 Homo sapiens chromosome 7open reading frame 26 (C7orf26), mRNA [NM_024067] NM_005340 HINT1 Homosapiens histidine triad nucleotide binding protein 1 (HINT1), mRNA[NM_005340] NM_177458 LYNX1 Homo sapiens Ly6/neurotoxin 1 (LYNX1),transcript variant SLURP2, mRNA [NM_177458] ENST00000325151ENST00000325151 Small inducible cytokine A27 precursor (CCL27) (CCchemokine ILC) (IL-11 R-alpha-locus chemokine) (Skinkine) (ESkine)(Cutaneous T-cell-attracting chemokine) (CTACK). [Source:Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_024958 NRSN2 Homosapiens neurensin 2 (NRSN2), mRNA [NM_024958] NM_144569 SPOCD1 Homosapiens SPOC domain containing 1 (SPOCD1), mRNA [NM_144569] NM_001017395TMCC1 Homo sapiens transmembrane and coiled-coil domain family 1(TMCC1), transcript variant 1, mRNA [NM_001017395] NM_178519 C17orf55Homo sapiens chromosome 17 open reading frame 55 (C17orf55), mRNA[NM_178519] THC2650296 THC2650296 RL18A_MOUSE (P62717) 60S ribosomalprotein L18a, complete [THC2650296] NM_001013 RPS9 Homo sapiensribosomal protein S9 (RPS9), mRNA [NM_001013] AA436686 AA436686 AA436686zv59a12.s1 Soares_testis_NHT Homo sapiens cDNA clone IMAGE: 757918 3′similar to contains Alu repetitive element;, mRNA sequence [AA436686]NM_138732 NRXN2 Homo sapiens neurexin 2 (NRXN2), transcript variantalpha-2, mRNA [NM_138732] NM_173473 C10orf104 Homo sapiens chromosome 10open reading frame 104 (C10orf104), mRNA [NM_173473] BC093850 C18orf23Homo sapiens chromosome 18 open reading frame 23, mRNA (cDNA clone MGC:120885 IMAGE: 7939695), complete cds. [BC093850] NM_005157 ABL1 Homosapiens v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1),transcript variant a, mRNA [NM_005157] NM_018166 C1orf78 Homo sapienschromosome 1 open reading frame 78 (C1orf78), mRNA [NM_018166]NM_001011724 RP11-78J21.1 Homo sapiens heterogeneous nuclearribonucleoprotein A1-like (LOC144983), transcript variant 1, mRNA[NM_001011724] NM_080746 RPL10L Homo sapiens ribosomal protein L10-like(RPL10L), mRNA [NM_080746] NM_207377 UNQ9438 Homo sapiens TIMM9(UNQ9438), mRNA [NM_207377] A_24_P641673 A_24_P641673 UnknownENST00000330370 LOC649839 PREDICTED: Homo sapiens similar to largesubunit ribosomal protein L36a (LOC649839), mRNA [XM_001129410]A_24_P698376 A_24_P698376 Unknown NM_033625 RPL34 Homo sapiens ribosomalprotein L34 (RPL34), transcript variant 2, mRNA [NM_033625] NM_001005862ERBB2 Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogenehomolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2),transcript variant 2, mRNA [NM_001005862] ENST00000313620 LOC342994PREDICTED: Homo sapiens similar to ribosomal protein L34 (LOC342994),mRNA [XM_938484] NM_015710 GLTSCR2 Homo sapiens glioma tumor suppressorcandidate region gene 2 (GLTSCR2), mRNA [NM_015710] NM_001416 EIF4A1Homo sapiens eukaryotic translation initiation factor 4A, isoform 1(EIF4A1), mRNA [NM_001416] BX641027 BX641027 Homo sapiens mRNA; cDNADKFZp686O10247 (from clone DKFZp686O10247). [BX641027] NM_003078 SMARCD3Homo sapiens SWI/SNF related, matrix associated, actin dependentregulator of chromatin, subfamily d, member 3 (SMARCD3), transcriptvariant 2, mRNA [NM_003078] NM_004450 ERH Homo sapiens enhancer ofrudimentary homolog (Drosophila) (ERH), mRNA [NM_004450] NM_001005291SREBF1 Homo sapiens sterol regulatory element binding transcriptionfactor 1 (SREBF1), transcript variant 1, mRNA [NM_001005291]A_24_P194954 A_24_P194954 Unknown NM_014362 HIBCH Homo sapiens3-hydroxyisobutyryl-Coenzyme A hydrolase (HIBCH), transcript variant 1,mRNA [NM_014362] XR_018187 LOC647722 PREDICTED: Homo sapiens similar toribosomal protein L3 isoform a (LOC647722), mRNA [XR_018187]NM_001018051 POLR3H Homo sapiens polymerase (RNA) III (DNA directed)polypeptide H (22.9 kD) (POLR3H), transcript variant 4, mRNA[NM_001018051] NM_145245 EVI5L Homo sapiens ecotropic viral integrationsite 5-like (EVI5L), mRNA [NM_145245] NM_016337 EVL Homo sapiensEnah/Vasp-like (EVL), mRNA [NM_016337] A_24_P736617 A_24_P736617 UnknownNM_032152 PRAM1 Homo sapiens PML-RARA regulated adaptor molecule 1(PRAM1), mRNA [NM_032152] NM_003202 TCF7 Homo sapiens transcriptionfactor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 1, mRNA[NM_003202] A_24_P587938 A_24_P587938 Unknown NM_203298 CHCHD1 Homosapiens coiled-coil-helix-coiled-coil-helix domain containing 1(CHCHD1), mRNA [NM_203298] THC2560098 THC2560098 S35960 C-terminal {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (64%) [THC2560098]NM_000948 PRL Homo sapiens prolactin (PRL), mRNA [NM_000948]A_24_P273074 A_24_P273074 Unknown NM_014367 C3orf28 Homo sapienschromosome 3 open reading frame 28 (C3orf28), mRNA [NM_014367] AY168775CXorf52 Homo sapiens SPCX mRNA, complete cds. [AY168775] NM_025073 SIKEHomo sapiens suppressor of IKK epsilon (SIKE), mRNA [NM_025073] AI291464AI291464 AI291464 qm73h06.x1 Soares_placenta_8to9weeks_2NbHP8to9W Homosapiens cDNA clone IMAGE: 1894427 3′, mRNA sequence [AI291464] NM_012225NUBP2 Homo sapiens nucleotide binding protein 2 (MinD homolog, E. coli)(NUBP2), mRNA [NM_012225] NM_080825 C20orf144 Homo sapiens chromosome 20open reading frame 144 (C20orf144), mRNA [NM_080825] NM_002229 JUNB Homosapiens jun B proto-oncogene (JUNB), mRNA [NM_002229] NM_203304 RKHD1Homo sapiens ring finger and KH domain containing 1 (RKHD1), mRNA[NM_203304] ENST00000356196 hCG_26523 PREDICTED: Homo sapiens similar to60S ribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)(LOC400055), mRNA [XM_374987] ENST00000311218 LOC401911 similar to 60Sribosomal protein L29 (Cell surface heparin-binding protein HIP)(LOC401911), mRNA [Source: RefSeq_dna; Acc: XR_016465] [ENST00000311218]NM_012317 LDOC1 Homo sapiens leucine zipper, down-regulated in cancer 1(LDOC1), mRNA [NM_012317] NM_015710 GLTSCR2 Homo sapiens glioma tumorsuppressor candidate region gene 2 (GLTSCR2), mRNA [NM_015710] XR_015536LOC731599 PREDICTED: Homo sapiens hypothetical protein LOC731599(LOC731599), mRNA [XR_015536] AX721252 AX721252 Sequence 212 from PatentWO0220754. [AX721252] NM_001009 RPS5 Homo sapiens ribosomal protein S5(RPS5), mRNA [NM_001009] NM_000972 RPL7A Homo sapiens ribosomal proteinL7a (RPL7A), mRNA [NM_000972] NM_006013 RPL10 Homo sapiens ribosomalprotein L10 (RPL10), mRNA [NM_006013] NM_003202 TCF7 Homo sapienstranscription factor 7 (T-cell specific, HMG-box) (TCF7), transcriptvariant 1, mRNA [NM_003202] A_24_P101271 A_24_P101271 Unknown NM_033199UCN2 Homo sapiens urocortin 2 (UCN2), mRNA [NM_033199] NM_003246 THBS1Homo sapiens thrombospondin 1 (THBS1), mRNA [NM_003246] XR_019375LOC645326 PREDICTED: Homo sapiens similar to laminin receptor 1(ribosomal protein SA) (LOC645326), mRNA [XR_019375] A_24_P929974A_24_P929974 Unknown NM_002624 PFDN5 Homo sapiens prefoldin subunit 5(PFDN5), transcript variant 1, mRNA [NM_002624] NM_005911 MAT2A Homosapiens methionine adenosyltransferase II, alpha (MAT2A), mRNA[NM_005911] NM_206819 MYBPC1 Homo sapiens myosin binding protein C, slowtype (MYBPC1), transcript variant 2, mRNA [NM_206819] A_24_P332292A_24_P332292 Unknown NM_000972 RPL7A Homo sapiens ribosomal protein L7a(RPL7A), mRNA [NM_000972] NM_001402 EEF1A1 Homo sapiens eukaryotictranslation elongation factor 1 alpha 1 (EEF1A1), mRNA [NM_001402]NM_033184 KRTAP2-4 Homo sapiens keratin associated protein 2-4(KRTAP2-4), mRNA [NM_033184] A_24_P169645 A_24_P169645 UnknownA_32_P77759 A_32_P77759 Unknown THC2584902 THC2584902 Q5M9L9_MOUSE(Q5M9L9) Ribosomal protein S8, partial (73%) [THC2584902] NM_030981RAB1B Homo sapiens RAB1B, member RAS oncogene family (RAB1B), mRNA[NM_030981] NM_000981 RPL19 Homo sapiens ribosomal protein L19 (RPL19),mRNA [NM_000981] NM_152525 ALS2CR11 Homo sapiens amyotrophic lateralsclerosis 2 (juvenile) chromosome region, candidate 11 (ALS2CR11), mRNA[NM_152525] NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9),transcript variant 1, mRNA [NM_000661] NM_016480 PAIP2 Homo sapienspoly(A) binding protein interacting protein 2 (PAIP2), transcriptvariant 2, mRNA [NM_016480] NM_004750 CRLF1 Homo sapiens cytokinereceptor-like factor 1 (CRLF1), mRNA [NM_004750] NM_006471 MRCL3 Homosapiens myosin regulatory light chain MRCL3 (MRCL3), mRNA [NM_006471]NM_033625 RPL34 Homo sapiens ribosomal protein L34 (RPL34), transcriptvariant 2, mRNA [NM_033625] NM_032378 EEF1D Homo sapiens eukaryotictranslation elongation factor 1 delta (guanine nucleotide exchangeprotein) (EEF1D), transcript variant 1, mRNA [NM_032378] CA503163CA503163 UI-CF-FN0-afp-1-04-0-UI.s1 UI-CF-FN0 Homo sapiens cDNA cloneUI-CF-FN0-afp-1-04-0-UI 3′, mRNA sequence [CA503163] NR_003110 CCT6AP1Homo sapiens chaperonin containing TCP1, subunit 6A (zeta 1) pseudogene1 (CCT6AP1) on chromosome 7 [NR_003110] NM_175065 HIST2H2AB Homo sapienshistone cluster 2, H2ab (HIST2H2AB), mRNA [NM_175065] NM_004714 DYRK1BHomo sapiens dual-specificity tyrosine-(Y)-phosphorylation regulatedkinase 1B (DYRK1B), transcript variant a, mRNA [NM_004714] X78926 ZNF268H. sapiens HZF3 mRNA for zinc finger protein. [X78926] NM_021038 MBNL1Homo sapiens muscleblind-like (Drosophila) (MBNL1), transcript variant1, mRNA [NM_021038] A_32_P231880 A_32_P231880 Unknown NM_015355 SUZ12Homo sapiens suppressor of zeste 12 homolog (Drosophila) (SUZ12), mRNA[NM_015355] NM_002124 HLA-DRB1 Homo sapiens major histocompatibilitycomplex, class II, DR beta 1 (HLA-DRB1), mRNA [NM_002124] BC014023BC014023 Homo sapiens cDNA clone IMAGE: 4309177, **** WARNING: chimericclone ****. [BC014023] A_24_P170103 A_24_P170103 Unknown A_32_P25838A_32_P25838 Unknown ENST00000332289 ENST00000332289 PREDICTED: Homosapiens similar to 40S ribosomal protein SA (p40) (34 [XR_019580]NM_013271 PCSK1N Homo sapiens proprotein convertase subtilisin/kexintype 1 inhibitor (PCSK1N), mRNA [NM_013271] AY037153 CAMTA1 Homo sapienshypothetical protein SB141 mRNA, complete cds. [AY037153] CR627135CR627135 Homo sapiens mRNA; cDNA DKFZp779J0122 (from cloneDKFZp779J0122). [CR627135] AK026675 AK026675 Homo sapiens cDNA: FLJ23022fis, clone LNG01117. [AK026675] XR_018545 LOC649228 PREDICTED: Homosapiens similar to 60S ribosomal protein L11 (LOC649228), mRNA[XR_018545] NM_014851 KLHL21 Homo sapiens kelch-like 21 (Drosophila)(KLHL21), mRNA [NM_014851] XR_018063 LOC392030 PREDICTED: Homo sapienshypothetical LOC392030 (LOC392030), mRNA [XR_018063] NM_017545 HAO1 Homosapiens hydroxyacid oxidase (glycolate oxidase) 1 (HAO1), mRNA[NM_017545] A_32_P101195 A_32_P101195 Unknown NM_000969 RPL5 Homosapiens ribosomal protein L5 (RPL5), mRNA [NM_000969] THC2646356THC2646356 Q2US65_ASPOR (Q2US65) Cytochrome P450 CYP3/CYP5/CYP6/CYP9subfamilies, partial (4%) [THC2646356] NM_033184 KRTAP2-4 Homo sapienskeratin associated protein 2-4 (KRTAP2-4), mRNA [NM_033184] A_24_P366445A_24_P366445 Unknown NM_024012 HTR5A Homo sapiens 5-hydroxytryptamine(serotonin) receptor 5A (HTR5A), mRNA [NM_024012] XR_018963 LOC442237PREDICTED: Homo sapiens similar to 40S ribosomal protein S7 (S8)(LOC442237), mRNA [XR_018963] A_24_P410070 A_24_P410070 UnknownNM_005646 TARBP1 Homo sapiens Tar (HIV-1) RNA binding protein 1(TARBP1), mRNA [NM_005646] XM_374010 LOC389033 PREDICTED: Homo sapienshypothetical LOC389033 (LOC389033), mRNA [XM_374010] NM_033251 RPL13Homo sapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] NM_000454 SOD1 Homo sapiens superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1 (adult)) (SOD1), mRNA [NM_000454]XR_015548 LOC729449 PREDICTED: Homo sapiens similar to 60S ribosomalprotein L7 (LOC729449), mRNA [XR_015548] THC2693842 THC2693842 UnknownA_24_P75399 A_24_P75399 Unknown NM_184041 ALDOA Homo sapiens aldolase A,fructose-bisphosphate (ALDOA), transcript variant 2, mRNA [NM_184041]NM_001031 RPS28 Homo sapiens ribosomal protein S28 (RPS28), mRNA[NM_001031] THC2533996 THC2533996 HSU09954 ribosomal protein L9 {Homosapiens} (exp = −1; wgp = 0; cg = 0), partial (42%) [THC2533996]NM_015937 PIGT Homo sapiens phosphatidylinositol glycan anchorbiosynthesis, class T (PIGT), mRNA [NM_015937] NM_006294 UQCRB Homosapiens ubiquinol-cytochrome c reductase binding protein (UQCRB), mRNA[NM_006294] NM_019059 TOMM7 Homo sapiens translocase of outermitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA [NM_019059]NM_001778 CD48 Homo sapiens CD48 molecule (CD48), mRNA [NM_001778]NM_032789 PARP10 Homo sapiens poly (ADP-ribose) polymerase family,member 10 (PARP10), mRNA [NM_032789] NR_002778 RPL29P2 Homo sapiensribosomal protein L29 pseudogene 2 (RPL29P2) on chromosome 17[NR_002778] THC2689192 THC2689192 Q7XC69_ORYSA (Q7XC69) Expressedprotein, partial (6%) [THC2689192] NM_000993 RPL31 Homo sapiensribosomal protein L31 (RPL31), mRNA [NM_000993] NM_000610 CD44 Homosapiens CD44 molecule (Indian blood group) (CD44), transcript variant 1,mRNA [NM_000610] NM_005538 INHBC Homo sapiens inhibin, beta C (INHBC),mRNA [NM_005538] NM_030928 CDT1 Homo sapiens chromatin licensing and DNAreplication factor 1 (CDT1), mRNA [NM_030928] BE843546 BE843546 BE843546CM3-TN0066-080800-269-g03 TN0066 Homo sapiens cDNA, mRNA sequence[BE843546] A_24_P714750 A_24_P714750 Unknown XR_018189 LOC401717PREDICTED: Homo sapiens similar to eukaryotic translation elongationfactor 1 alpha 2 (LOC401717), mRNA [XR_018189] NM_003614 GALR3 Homosapiens galanin receptor 3 (GALR3), mRNA [NM_003614] NM_007262 PARK7Homo sapiens Parkinson disease (autosomal recessive, early onset) 7(PARK7), mRNA [NM_007262] NM_006738 AKAP13 Homo sapiens A kinase (PRKA)anchor protein 13 (AKAP13), transcript variant 1, mRNA [NM_006738]NM_017801 CMTM6 Homo sapiens CKLF-like MARVEL transmembrane domaincontaining 6 (CMTM6), mRNA [NM_017801] ENST00000332500 PTP4A2 Proteintyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosinephosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2)(PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1). [Source: Uniprot/SWISSPROT; Acc:Q12974] [ENST00000332500] NM_002421 MMP1 Homo sapiens matrixmetallopeptidase 1 (interstitial collagenase) (MMP1), mRNA [NM_002421]NM_016270 KLF2 Homo sapiens Kruppel-like factor 2 (lung) (KLF2), mRNA[NM_016270] NM_017881 C9orf95 Homo sapiens chromosome 9 open readingframe 95 (C9orf95), mRNA [NM_017881] NM_000428 LTBP2 Homo sapiens latenttransforming growth factor beta binding protein 2 (LTBP2), mRNA[NM_000428] XR_017260 LOC646710 PREDICTED: Homo sapiens hypotheticalLOC646710 (LOC646710), mRNA [XR_017260] NM_024812 BAALC Homo sapiensbrain and acute leukemia, cytoplasmic (BAALC), transcript variant 1,mRNA [NM_024812] NM_030979 PABPC3 Homo sapiens poly(A) binding protein,cytoplasmic 3 (PABPC3), mRNA [NM_030979] XR_018341 LOC390413 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC390413), mRNA[XR_018341] NM_000970 RPL6 Homo sapiens ribosomal protein L6 (RPL6),transcript variant 2, mRNA [NM_000970] BC048265 LOC439990 Homo sapienshypothetical gene supported by BC009626; BC048265, mRNA (cDNA cloneIMAGE: 4400050). [BC048265] NM_001042646 TRAK1 Homo sapiens traffickingprotein, kinesin binding 1 (TRAK1), transcript variant 1, mRNA[NM_001042646] XR_016779 LOC440311 PREDICTED: Homo sapiens similar toGlioma tumor suppressor candidate region gene 2 protein (p60)(LOC440311), mRNA [XR_016779] NM_001080418 DLGAP3 Homo sapiens discs,large (Drosophila) homolog-associated protein 3 (DLGAP3), mRNA[NM_001080418] BC018095 BC018095 Homo sapiens cDNA clone IMAGE: 4793786.[BC018095] NM_003508 FZD9 Homo sapiens frizzled homolog 9 (Drosophila)(FZD9), mRNA [NM_003508] NM_000453 SLC5A5 Homo sapiens solute carrierfamily 5 (sodium iodide symporter), member 5 (SLC5A5), mRNA [NM_000453]NM_016104 RWDD1 Homo sapiens RWD domain containing 1 (RWDD1), transcriptvariant 2, mRNA [NM_016104] NM_207322 NLF1 Homo sapiens nuclearlocalized factor 1 (NLF1), mRNA [NM_207322] BC103878 MOGAT2 Homo sapiensmonoacylglycerol O-acyltransferase 2, mRNA (cDNA clone MGC: 119185IMAGE: 40004283), complete cds. [BC103878] A_24_P572229 A_24_P572229Unknown NM_022356 LEPRE1 Homo sapiens leucine proline-enrichedproteoglycan (leprecan) 1 (LEPRE1), mRNA [NM_022356] NM_080392 PTP4A2Homo sapiens protein tyrosine phosphatase type IVA, member 2 (PTP4A2),transcript variant 2, mRNA [NM_080392] NM_002307 LGALS7 Homo sapienslectin, galactoside-binding, soluble, 7 (galectin 7) (LGALS7), mRNA[NM_002307] NM_001042519 MGC13057 Homo sapiens hypothetical proteinMGC13057 (MGC13057), transcript variant 1, mRNA [NM_001042519] NM_023078PYCRL Homo sapiens pyrroline-5-carboxylate reductase-like (PYCRL), mRNA[NM_023078] XR_018052 LOC442288 PREDICTED: Homo sapiens similar to 60Sribosomal protein L7a (LOC442288), mRNA [XR_018052] NM_000979 RPL18 Homosapiens ribosomal protein L18 (RPL18), mRNA [NM_000979] NM_013354 CNOT7Homo sapiens CCR4-NOT transcription complex, subunit 7 (CNOT7),transcript variant 1, mRNA [NM_013354] XR_018054 LOC392878 PREDICTED:Homo sapiens hypothetical LOC392878 (LOC392878), mRNA [XR_018054]AF100640 AF100640 Homo sapiens metastasis related protein (MB2) mRNA,partial cds. [AF100640] NM_014248 RBX1 Homo sapiens ring-box 1 (RBX1),mRNA [NM_014248] NM_001005472 LOC388524 Homo sapiens similar to Lamininreceptor 1 (LOC388524), mRNA [NM_001005472] ENST00000381140ENST00000381140 Transcription factor IIIA (Factor A) (TFIIIA). [Source:Uniprot/SWISSPROT; Acc: Q92664] [ENST00000381140] NM_018326 GIMAP4 Homosapiens GTPase, IMAP family member 4 (GIMAP4), mRNA [NM_018326]NM_013234 EIF3S12 Homo sapiens eukaryotic translation initiation factor3, subunit 12 (EIF3S12), mRNA [NM_013234] NM_172006 WFDC10B Homo sapiensWAP four-disulfide core domain 10B (WFDC10B), transcript variant 1, mRNA[NM_172006] BC024303 FLJ35390 Homo sapiens hypothetical proteinFLJ35390, mRNA (cDNA clone IMAGE: 4328569), with apparent retainedintron. [BC024303] NM_000982 RPL21 Homo sapiens ribosomal protein L21(RPL21), mRNA [NM_000982] NM_000454 SOD1 Homo sapiens superoxidedismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) (SOD1),mRNA [NM_000454] NM_024676 C1orf113 Homo sapiens chromosome 1 openreading frame 113 (C1orf113), mRNA [NM_024676] A_24_P850187 A_24_P850187Unknown THC2513403 THC2513403 HUMBCAA Br-cadherin {Homo sapiens} (exp =−1; wgp = 0; cg = 0), partial (13%) [THC2513403] NM_006285 TESK1 Homosapiens testis-specific kinase 1 (TESK1), mRNA [NM_006285] NM_000988RPL27 Homo sapiens ribosomal protein L27 (RPL27), mRNA [NM_000988]NM_020836 KIAA1446 Homo sapiens likely ortholog of rat brain-enrichedguanylate kinase-associated protein (KIAA1446), mRNA [NM_020836]NM_032611 PTP4A3 Homo sapiens protein tyrosine phosphatase type IVA,member 3 (PTP4A3), transcript variant 1, mRNA [NM_032611] AI751518AI751518 AI751518 cn10d09.y1 Normal Human Trabecular Bone Cells Homosapiens cDNA clone NHTBC_cn10d09 random, mRNA sequence [AI751518]NM_001465 FYB Homo sapiens FYN binding protein (FYB-120/130) (FYB),transcript variant 1, mRNA [NM_001465] BC018681 NDST2 Homo sapiensN-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2, mRNA (cDNAclone IMAGE: 4665687), partial cds. [BC018681] A_24_P67308 A_24_P67308Unknown ENST00000329784 ENST00000329784 PREDICTED: Homo sapiens similarto large subunit ribosomal protein L36a (LOC284230), mRNA [XM_208185]NM_001004 RPLP2 Homo sapiens ribosomal protein, large, P2 (RPLP2), mRNA[NM_001004] A_24_P298320 A_24_P298320 Unknown NM_016055 MRPL48 Homosapiens mitochondrial ribosomal protein L48 (MRPL48), nuclear geneencoding mitochondrial protein, mRNA [NM_016055] BC064430 LOC205251 Homosapiens cDNA clone IMAGE: 5763979. [BC064430] BC069765 C15orf5 Homosapiens chromosome 15 open reading frame 5, mRNA (cDNA clone MGC: 97283IMAGE: 7262532), complete cds. [BC069765] THC2719015 THC2719015 UnknownTHC2675117 THC2675117 D90774 RecT protein (P33). {Escherichia coli} (exp= −1; wgp = 0; cg = 0), partial (5%) [THC2675117] NM_001404 EEF1G Homosapiens eukaryotic translation elongation factor 1 gamma (EEF1G), mRNA[NM_001404] NM_001293 CLNS1A Homo sapiens chloride channel,nucleotide-sensitive, 1A (CLNS1A), mRNA [NM_001293] NM_002945 RPA1 Homosapiens replication protein A1, 70 kDa (RPA1), mRNA [NM_002945]NM_006830 UQCR Homo sapiens ubiquinol-cytochrome c reductase, 6.4 kDasubunit (UQCR), mRNA [NM_006830] AF318380 AF318380 Homo sapiens pp9943mRNA, complete cds. [AF318380] NM_001039211 ATAD3C Homo sapiens ATPasefamily, AAA domain containing 3C (ATAD3C), mRNA [NM_001039211] NM_003145SSR2 Homo sapiens signal sequence receptor, beta (translocon-associatedprotein beta) (SSR2), mRNA [NM_003145] NM_001967 EIF4A2 Homo sapienseukaryotic translation initiation factor 4A, isoform 2 (EIF4A2), mRNA[NM_001967] NM_001011 RPS7 Homo sapiens ribosomal protein S7 (RPS7),mRNA [NM_001011] NM_001007 RPS4X Homo sapiens ribosomal protein S4,X-linked (RPS4X), mRNA [NM_001007] NM_173571 RP6-166C19.11 Homo sapienscancer/testis CT47 family, member 11 (CT47.11), mRNA [NM_173571]NM_004907 IER2 Homo sapiens immediate early response 2 (IER2), mRNA[NM_004907] ENST00000333351 ENST00000333351 PREDICTED: Homo sapienshypothetical LOC391504 (LOC391504), mRNA [XR_018627] NM_001122 ADFP Homosapiens adipose differentiation-related protein (ADFP), mRNA [NM_001122]NM_152540 SCFD2 Homo sapiens sec1 family domain containing 2 (SCFD2),mRNA [NM_152540] A_24_P204474 A_24_P204474 Unknown BC004968 MGC2664 Homosapiens, clone IMAGE: 3543963, mRNA. [BC004968] NM_001028 RPS25 Homosapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] NM_001861 COX4I1Homo sapiens cytochrome c oxidase subunit IV isoform 1 (COX4I1), mRNA[NM_001861] NM_178230 PPIAL4 Homo sapiens peptidylprolyl isomerase A(cyclophilin A)-like 4 (PPIAL4), mRNA [NM_178230] ENST00000256969C12orf39 Uncharacterized protein C12orf39 precursor [Contains: Putativeamidated peptide NWTPQAMLYLKGAQ]. [Source: Uniprot/SWISSPROT; Acc:Q9BT56] [ENST00000256969] A_24_P196024 A_24_P196024 Unknown NM_006671SLC1A7 Homo sapiens solute carrier family 1 (glutamate transporter),member 7 (SLC1A7), mRNA [NM_006671] NM_002118 HLA-DMB Homo sapiens majorhistocompatibility complex, class II, DM beta (HLA-DMB), mRNA[NM_002118] BU956542 BU956542 BU956542 AGENCOURT_10615527 NIH_MGC_107Homo sapiens cDNA clone IMAGE: 6730153 5′, mRNA sequence [BU956542]AK057161 MEF2B Homo sapiens cDNA FLJ32599 fis, clone STOMA1000047.[AK057161] NM_017549 EPDR1 Homo sapiens ependymin related protein 1(zebrafish) (EPDR1), mRNA [NM_017549] NM_033342 TRIM7 Homo sapienstripartite motif-containing 7 (TRIM7), transcript variant 6, mRNA[NM_033342] AL547890 AL547890 AL547890 AL547890 Homo sapiens PLACENTACOT 25- NORMALILED Homo sapiens cDNA clone CS0DI033YB09 5- PRIME, mRNAsequence [AL547890] THC2726954 THC2726954 Q5Y2C1_9STRA (Q5Y2C1)Silaffin, partial (4%) [THC2726954] A_24_P392790 A_24_P392790 UnknownNM_001537 HSBP1 Homo sapiens heat shock factor binding protein 1(HSBP1), mRNA [NM_001537] XR_017498 LOC645693 PREDICTED: Homo sapienssimilar to eukaryotic translation elongation factor 1 alpha 2(LOC645693), mRNA [XR_017498] THC2745287 THC2745287 Q6C3B8_YARLI(Q6C3B8) Similarity, partial (10%) [THC2745287] BC001697 RPS15A Homosapiens ribosomal protein S15a, mRNA (cDNA clone MGC: 2466 IMAGE:2967511), complete cds. [BC001697] NM_003754 EIF3S5 Homo sapienseukaryotic translation initiation factor 3, subunit 5 epsilon, 47 kDa(EIF3S5), mRNA [NM_003754] NM_001008 RPS4Y1 Homo sapiens ribosomalprotein S4, Y-linked 1 (RPS4Y1), mRNA [NM_001008] NM_002405 MFNG Homosapiens MFNG O-fucosylpeptide 3-beta-N- acetylglucosaminyltransferase(MFNG), mRNA [NM_002405] A_24_P324224 A_24_P324224 Unknown A_24_P714620A_24_P714620 Unknown NM_030912 TRIM8 Homo sapiens tripartitemotif-containing 8 (TRIM8), mRNA [NM_030912] NM_001017418 SPRR2B Homosapiens small proline-rich protein 2B (SPRR2B), mRNA [NM_001017418]THC2529969 THC2529969 Unknown NM_015853 LOC51035 Homo sapiens SAPKsubstrate protein 1 (LOC51035), mRNA [NM_015853] NM_020246 SLC12A9 Homosapiens solute carrier family 12 (potassium/chloride transporters),member 9 (SLC12A9), mRNA [NM_020246] NM_152429 FGFBP3 Homo sapiensfibroblast growth factor binding protein 3 (FGFBP3), mRNA [NM_152429]A_24_P50567 A_24_P50567 Unknown NM_018949 UTS2R Homo sapiens urotensin 2receptor (UTS2R), mRNA [NM_018949] NM_002397 MEF2C Homo sapiens MADS boxtranscription enhancer factor 2, polypeptide C (myocyte enhancer factor2C) (MEF2C), mRNA [NM_002397] NM_001005472 LOC388524 Homo sapienssimilar to Laminin receptor 1 (LOC388524), mRNA [NM_001005472] XR_019242LOC402149 PREDICTED: Homo sapiens similar to ribosomal protein L28(LOC402149), mRNA [XR_019242] NM_198175 NME1 Homo sapiens non-metastaticcells 1, protein (NM23A) expressed in (NME1), transcript variant 1, mRNA[NM_198175] NM_014335 EID1 Homo sapiens EP300 interacting inhibitor ofdifferentiation 1 (EID1), mRNA [NM_014335] AF147440 AF147440 Homosapiens full length insert cDNA clone YP90G10. [AF147440] A_24_P375435A_24_P375435 Unknown NM_007369 GPR161 Homo sapiens G protein-coupledreceptor 161 (GPR161), transcript variant 1, mRNA [NM_007369] S76980HEXA HEXA {HEXA4bpDeltaA mutation, exon 11} [human, Tay-Sachs diseasepatient, mRNA Partial Mutant, 78 nt]. [S76980] NM_000967 RPL3 Homosapiens ribosomal protein L3 (RPL3), transcript variant 1, mRNA[NM_000967] NM_001568 EIF3S6 Homo sapiens eukaryotic translationinitiation factor 3, subunit 6 48 kDa (EIF3S6), mRNA [NM_001568]NM_015646 RAP1B Homo sapiens RAP1B, member of RAS oncogene family(RAP1B), transcript variant 1, mRNA [NM_015646] NM_001436 FBL Homosapiens fibrillarin (FBL), mRNA [NM_001436] NM_005356 LCK Homo sapienslymphocyte-specific protein tyrosine kinase (LCK), transcript variant 2,mRNA [NM_005356] NM_002350 LYN Homo sapiens v-yes-1 Yamaguchi sarcomaviral related oncogene homolog (LYN), mRNA [NM_002350] A_24_P212726A_24_P212726 Unknown A_24_P367139 A_24_P367139 Unknown NM_006682 FGL2Homo sapiens fibrinogen-like 2 (FGL2), mRNA [NM_006682] A_24_P332326A_24_P332326 Unknown NM_033251 RPL13 Homo sapiens ribosomal protein L13(RPL13), transcript variant 2, mRNA [NM_033251] A_24_P144383A_24_P144383 Unknown NM_001010938 TNK2 Homo sapiens tyrosine kinase,non-receptor, 2 (TNK2), transcript variant 2, mRNA [NM_001010938]AK026078 AK026078 Homo sapiens cDNA: FLJ22425 fis, clone HRC08686.[AK026078] THC2529614 THC2529614 Q3VHI9_9SPHN (Q3VHI9) Manganese andiron superoxide dismutase precursor, partial (8%) [THC2529614] NM_145690YWHAZ Homo sapiens tyrosine 3-monooxygenase/tryptophan 5- monooxygenaseactivation protein, zeta polypeptide (YWHAZ), transcript variant 2, mRNA[NM_145690] NM_001014 RPS10 Homo sapiens ribosomal protein S10 (RPS10),mRNA [NM_001014] A_24_P290114 A_24_P290114 Unknown XR_017294 LOC646949PREDICTED: Homo sapiens similar to ribosomal protein L23 (LOC646949),mRNA [XR_017294] E01979 E01979 CD671824 fg07f07.x1 Human Iris cDNA(Normalized): fg Homo sapiens cDNA clone fg07f07 3′, mRNA sequence[CD671824] NM_013232 PDCD6 Homo sapiens programmed cell death 6 (PDCD6),mRNA [NM_013232] NM_001212 C1QBP Homo sapiens complement component 1, qsubcomponent binding protein (C1QBP), nuclear gene encodingmitochondrial protein, mRNA [NM_001212] XR_018025 LOC641790 PREDICTED:Homo sapiens similar to ribosomal protein L31 (LOC641790), mRNA[XR_018025] NM_019839 LTB4R2 Homo sapiens leukotriene B4 receptor 2(LTB4R2), mRNA [NM_019839] NM_001019 RPS15A Homo sapiens ribosomalprotein S15a (RPS15A), transcript variant 2, mRNA [NM_001019] NM_004810GRAP2 Homo sapiens GRB2-related adaptor protein 2 (GRAP2), mRNA[NM_004810] NM_182623 FAM131C Homo sapiens family with sequencesimilarity 131, member C (FAM131C), mRNA [NM_182623] NM_001961 EEF2 Homosapiens eukaryotic translation elongation factor 2 (EEF2), mRNA[NM_001961] A_24_P289884 A_24_P289884 Unknown A_23_P200955 A_23_P200955Unknown NM_016824 ADD3 Homo sapiens adducin 3 (gamma) (ADD3), transcriptvariant 1, mRNA [NM_016824] ENST00000239730 ENST00000239730 Novelprotein. [Source: Uniprot/SPTREMBL; Acc: Q5W161] [ENST00000239730]NR_001577 NME2P1 Homo sapiens non-metastatic cells 2, protein (NM23B)expressed in, pseudogene 1 (NME2P1) on chromosome 12 [NR_001577]NM_021198 CTDSP1 Homo sapiens CTD (carboxy-terminal domain, RNApolymerase II, polypeptide A) small phosphatase 1 (CTDSP1), transcriptvariant 1, mRNA [NM_021198] NM_006597 HSPA8 Homo sapiens heat shock 70kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597] BC005008CEACAM6 Homo sapiens carcinoembryonic antigen-related cell adhesionmolecule 6 (non-specific cross reacting antigen), mRNA (cDNA clone MGC:10467 IMAGE: 3640231), complete cds. [BC005008] NM_003757 EIF3S2 Homosapiens eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa (EIF3S2), mRNA [NM_003757] THC2647276 THC2647276 UnknownA_24_P255252 A_24_P255252 Unknown NM_001402 EEF1A1 Homo sapienseukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA[NM_001402] XR_018386 LOC392358 PREDICTED: Homo sapiens similar to 40Sribosomal protein S6 (LOC392358), mRNA [XR_018386] NM_001005472LOC388524 Homo sapiens similar to Laminin receptor 1 (LOC388524), mRNA[NM_001005472] BC067891 LOC645683 Homo sapiens cDNA clone MGC: 87657IMAGE: 5271409, complete cds. [BC067891] NM_021130 PPIA Homo sapienspeptidylprolyl isomerase A (cyclophilin A) (PPIA), mRNA [NM_021130]NM_002037 FYN Homo sapiens FYN oncogene related to SRC, FGR, YES (FYN),transcript variant 1, mRNA [NM_002037] A_24_P505981 A_24_P505981 UnknownNM_005401 PTPN14 Homo sapiens protein tyrosine phosphatase, non-receptortype 14 (PTPN14), mRNA [NM_005401] NM_031918 KLF16 Homo sapiensKruppel-like factor 16 (KLF16), mRNA [NM_031918] NM_000454 SOD1 Homosapiens superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1(adult)) (SOD1), mRNA [NM_000454] NR_003246 FLJ40113 Homo sapiens golgiautoantigen, golgin subfamily a-like pseudogene (FLJ40113) on chromosome15 [NR_003246] XR_015785 LOC402643 PREDICTED: Homo sapiens tropomyosin3-like (LOC402643), misc RNA [XR_015785] NM_001010 RPS6 Homo sapiensribosomal protein S6 (RPS6), mRNA [NM_001010]

TABLE 17 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻²and the log-median-ratio being at least “1” or above or being at least“−1” or below. The p-values were corrected using Benjamin and Hochbergmethod. Genbank Accession Gene Name Description NM_001039567 RPS4Y2 Homosapiens ribosomal protein S4, Y-linked 2 (RPS4Y2), mRNA [NM_001039567]NM_183049 TMSL3 Homo sapiens thymosin-like 3 (TMSL3), mRNA [NM_183049]NM_001008 RPS4Y1 Homo sapiens ribosomal protein S4, Y-linked 1 (RPS4Y1),mRNA [NM_001008] NM_004126 GNG11 Homo sapiens guanine nucleotide bindingprotein (G protein), gamma 11 (GNG11), mRNA [NM_004126] NM_002985 CCL5Homo sapiens chemokine (C-C motif) ligand 5 (CCL5), mRNA [NM_002985]A_24_P530977 A_24_P530977 Unknown NM_004048 B2M Homo sapiensbeta-2-microglobulin (B2M), mRNA [NM_004048] NM_004907 IER2 Homo sapiensimmediate early response 2 (IER2), mRNA [NM_004907] NM_001005339 RGS10Homo sapiens regulator of G-protein signalling 10 (RGS10), transcriptvariant 1, mRNA [NM_001005339] NM_201397 GPX1 Homo sapiens glutathioneperoxidase 1 (GPX1), transcript variant 2, mRNA [NM_201397] NM_015646RAP1B Homo sapiens RAP1B, member of RAS oncogene family (RAP1B),transcript variant 1, mRNA [NM_015646] AL049447 AL049447 Homo sapiensmRNA; cDNA DKFZp586A0722 (from clone DKFZp586A0722). [AL049447]NM_031286 SH3BGRL3 Homo sapiens SH3 domain binding glutamic acid-richprotein like 3 (SH3BGRL3), mRNA [NM_031286] NM_012329 MMD Homo sapiensmonocyte to macrophage differentiation- associated (MMD), mRNA[NM_012329] NM_002620 PF4V1 Homo sapiens platelet factor 4 variant 1(PF4V1), mRNA [NM_002620] NM_001004 RPLP2 Homo sapiens ribosomalprotein, large, P2 (RPLP2), mRNA [NM_001004] NM_033251 RPL13 Homosapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] ENST00000383061 ENST00000383061 PREDICTED: Homo sapienssimilar to myosin regulatory light chain-like (LOC442204), mRNA[XM_498088] NM_004907 IER2 Homo sapiens immediate early response 2(IER2), mRNA [NM_004907] NM_001803 CD52 Homo sapiens CD52 molecule(CD52), mRNA [NM_001803] NM_145113 MAX Homo sapiens MYC associatedfactor X (MAX), transcript variant 3, mRNA [NM_145113] NM_002954 RPS27AHomo sapiens ribosomal protein S27a (RPS27A), mRNA [NM_002954] NM_006471MRCL3 Homo sapiens myosin regulatory light chain MRCL3 (MRCL3), mRNA[NM_006471] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_001030 RPS27 Homosapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA[NM_001030] NM_080425 GNAS Homo sapiens GNAS complex locus (GNAS),transcript variant 2, mRNA [NM_080425] NM_001032 RPS29 Homo sapiensribosomal protein S29 (RPS29), transcript variant 1, mRNA [NM_001032]NM_001012 RPS8 Homo sapiens ribosomal protein S8 (RPS8), mRNA[NM_001012] XR_017498 LOC645693 PREDICTED: Homo sapiens similar toeukaryotic translation elongation factor 1 alpha 2 (LOC645693), mRNA[XR_017498] NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8(HSPA8), transcript variant 1, mRNA [NM_006597] NM_001030 RPS27 Homosapiens ribosomal protein S27 (metallopanstimulin 1) (RPS27), mRNA[NM_001030] A_24_P229756 A_24_P229756 Unknown THC2544911 THC2544911MUSEFTU elongation factor Tu {Mus musculus} (exp = −1; wgp = 0; cg = 0),partial (37%) [THC2544911] NM_021104 RPL41 Homo sapiens ribosomalprotein L41 (RPL41), transcript variant 1, mRNA [NM_021104] NM_000981RPL19 Homo sapiens ribosomal protein L19 (RPL19), mRNA [NM_000981]A_24_P929974 A_24_P929974 Unknown NM_002300 LDHB Homo sapiens lactatedehydrogenase B (LDHB), mRNA [NM_002300] NM_001031 RPS28 Homo sapiensribosomal protein S28 (RPS28), mRNA [NM_001031] NM_000978 RPL23 Homosapiens ribosomal protein L23 (RPL23), mRNA [NM_000978] NM_033251 RPL13Homo sapiens ribosomal protein L13 (RPL13), transcript variant 2, mRNA[NM_033251] NM_001003 RPLP1 Homo sapiens ribosomal protein, large, P1(RPLP1), transcript variant 1, mRNA [NM_001003] NM_001028 RPS25 Homosapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] NM_001032 RPS29Homo sapiens ribosomal protein S29 (RPS29), transcript variant 1, mRNA[NM_001032] A_24_P238426 A_24_P238426 Unknown NM_018447 TMEM111 Homosapiens transmembrane protein 111 (TMEM111), mRNA [NM_018447] BX096698BX096698 BX096698 Soares breast 2NbHBst Homo sapiens cDNA cloneIMAGp998E11242, mRNA sequence [BX096698] NM_001003 RPLP1 Homo sapiensribosomal protein, large, P1 (RPLP1), transcript variant 1, mRNA[NM_001003] NM_002823 PTMA Homo sapiens prothymosin, alpha (genesequence 28) (PTMA), mRNA [NM_002823] NM_033251 RPL13 Homo sapiensribosomal protein L13 (RPL13), transcript variant 2, mRNA [NM_033251]XR_017294 LOC646949 PREDICTED: Homo sapiens similar to ribosomal proteinL23 (LOC646949), mRNA [XR_017294] NM_000993 RPL31 Homo sapiens ribosomalprotein L31 (RPL31), mRNA [NM_000993] XR_015548 LOC729449 PREDICTED:Homo sapiens similar to 60S ribosomal protein L7 (LOC729449), mRNA[XR_015548] BC052613 LOC728131 Homo sapiens cDNA clone MGC: 59872 IMAGE:6301163, complete cds. [BC052613] A_24_P306968 A_24_P306968 UnknownXM_497657 LOC441876 PREDICTED: Homo sapiens similar to 40S ribosomalprotein S16, transcript variant 1 (LOC441876), mRNA [XM_497657]NM_001025 RPS23 Homo sapiens ribosomal protein S23 (RPS23), mRNA[NM_001025] BU956542 BU956542 BU956542 AGENCOURT_10615527 NIH_MGC_107Homo sapiens cDNA clone IMAGE: 6730153 5′, mRNA sequence [BU956542]NM_006597 HSPA8 Homo sapiens heat shock 70 kDa protein 8 (HSPA8),transcript variant 1, mRNA [NM_006597] NM_001402 EEF1A1 Homo sapienseukaryotic translation elongation factor 1 alpha 1 (EEF1A1), mRNA[NM_001402] NM_000975 RPL11 Homo sapiens ribosomal protein L11 (RPL11),mRNA [NM_000975] NR_003038 SNHG5 Homo sapiens small nucleolar RNA hostgene (non-protein coding) 5 (SNHG5) on chromosome 6 [NR_003038]NM_015710 GLTSCR2 Homo sapiens glioma tumor suppressor candidate regiongene 2 (GLTSCR2), mRNA [NM_015710] A_24_P332292 A_24_P332292 UnknownNM_000989 RPL30 Homo sapiens ribosomal protein L30 (RPL30), mRNA[NM_000989] NM_000989 RPL30 Homo sapiens ribosomal protein L30 (RPL30),mRNA [NM_000989] CR620748 LOC729329 full-length cDNA clone CS0DK011YI14of HeLa cells Cot 25- normalized of Homo sapiens (human) [CR620748]ENST00000337102 ENST00000337102 40S ribosomal protein S21. [Source:Uniprot/SWISSPROT; Acc: P63220] [ENST00000337102] XR_018138 LOC392497PREDICTED: Homo sapiens similar to 40S ribosomal protein S6 (LOC392497),mRNA [XR_018138] NM_002341 LTB Homo sapiens lymphotoxin beta (TNFsuperfamily, member 3) (LTB), transcript variant 1, mRNA [NM_002341]NM_000967 RPL3 Homo sapiens ribosomal protein L3 (RPL3), transcriptvariant 1, mRNA [NM_000967] A_24_P84408 A_24_P84408 Unknown NM_000661RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcript variant 1,mRNA [NM_000661] NM_000991 RPL28 Homo sapiens ribosomal protein L28(RPL28), mRNA [NM_000991] NM_000661 RPL9 Homo sapiens ribosomal proteinL9 (RPL9), transcript variant 1, mRNA [NM_000661] A_24_P50567A_24_P50567 Unknown A_24_P298238 A_24_P298238 Unknown NM_003295 TPT1Homo sapiens tumor protein, translationally-controlled 1 (TPT1), mRNA[NM_003295] BC018140 RPS21 Homo sapiens ribosomal protein S21, mRNA(cDNA clone MGC: 9438 IMAGE: 3903320), complete cds. [BC018140] BC067891LOC645683 Homo sapiens cDNA clone MGC: 87657 IMAGE: 5271409, completecds. [BC067891] NM_001028 RPS25 Homo sapiens ribosomal protein S25(RPS25), mRNA [NM_001028] THC2567891 THC2567891 Q6NXR8_HUMAN (Q6NXR8)Ribosomal protein S3a, partial (91%) [THC2567891] NM_000988 RPL27 Homosapiens ribosomal protein L27 (RPL27), mRNA [NM_000988] NM_000978 RPL23Homo sapiens ribosomal protein L23 (RPL23), mRNA [NM_000978] BC001697RPS15A Homo sapiens ribosomal protein S15a, mRNA (cDNA clone MGC: 2466IMAGE: 2967511), complete cds. [BC001697] A_24_P862524 A_24_P862524Unknown NM_001007074 RPL32 Homo sapiens ribosomal protein L32 (RPL32),transcript variant 3, mRNA [NM_001007074] A_24_P41979 A_24_P41979Unknown A_23_P210285 A_23_P210285 Unknown NM_003973 RPL14 Homo sapiensribosomal protein L14 (RPL14), transcript variant 2, mRNA [NM_003973]A_24_P255252 A_24_P255252 Unknown NM_002954 RPS27A Homo sapiensribosomal protein S27a (RPS27A), mRNA [NM_002954] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] NM_001016RPS12 Homo sapiens ribosomal protein S12 (RPS12), mRNA [NM_001016]NM_003295 TPT1 Homo sapiens tumor protein, translationally-controlled 1(TPT1), mRNA [NM_003295] NM_033625 RPL34 Homo sapiens ribosomal proteinL34 (RPL34), transcript variant 2, mRNA [NM_033625] XR_015936 LOC731457PREDICTED: Homo sapiens similar to ribosomal protein S27a (LOC731457),mRNA [XR_015936] XR_018222 RPL31P4 PREDICTED: Homo sapiens ribosomalprotein L31 pseudogene 4 (RPL31P4), mRNA [XR_018222] A_24_P367063A_24_P367063 Unknown NM_001010 RPS6 Homo sapiens ribosomal protein S6(RPS6), mRNA [NM_001010] NM_033625 RPL34 Homo sapiens ribosomal proteinL34 (RPL34), transcript variant 2, mRNA [NM_033625] NM_022551 RPS18 Homosapiens ribosomal protein S18 (RPS18), mRNA [NM_022551] NM_001028 RPS25Homo sapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] XR_018695RPL31P10 PREDICTED: Homo sapiens similar to ribosomal protein L31(LOC390283), mRNA [XR_018695] ENST00000356196 hCG_26523 PREDICTED: Homosapiens similar to 60S ribosomal protein L26 (LOC646161), mRNA[XR_018048] ENST00000356196 hCG_26523 PREDICTED: Homo sapiens similar to60S ribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)(LOC400055), mRNA [XM_374987] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] XR_018048LOC646161 PREDICTED: Homo sapiens similar to 60S ribosomal protein L26(LOC646161), mRNA [XR_018048] NM_003295 TPT1 Homo sapiens tumor protein,translationally-controlled 1 (TPT1), mRNA [NM_003295] NM_000986 RPL24Homo sapiens ribosomal protein L24 (RPL24), mRNA [NM_000986]ENST00000313620 LOC342994 PREDICTED: Homo sapiens similar to ribosomalprotein L34 (LOC342994), mRNA [XM_938484] THC2506377 THC2506377 HSU02032ribosomal protein L23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0),partial (92%) [THC2506377] NM_002568 PABPC1 Homo sapiens poly(A) bindingprotein, cytoplasmic 1 (PABPC1), mRNA [NM_002568] NM_000997 RPL37 Homosapiens ribosomal protein L37 (RPL37), mRNA [NM_000997] XR_018303LOC648378 PREDICTED: Homo sapiens similar to ribosomal protein S14(LOC648378), mRNA [XR_018303] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] NM_001023RPS20 Homo sapiens ribosomal protein S20 (RPS20), mRNA [NM_001023]NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14), transcriptvariant 2, mRNA [NM_003973] NM_001006 RPS3A Homo sapiens ribosomalprotein S3A (RPS3A), mRNA [NM_001006] NM_001024 RPS21 Homo sapiensribosomal protein S21 (RPS21), mRNA [NM_001024] NM_001021 RPS17 Homosapiens ribosomal protein S17 (RPS17), mRNA [NM_001021] NM_002823 PTMAHomo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA[NM_002823] ENST00000357697 ENST00000357697 Unknown XM_372498 LOC390427PREDICTED: Homo sapiens similar to TBP-associated factor 15 isoform 1(LOC390427), mRNA [XM_372498] NM_173078 SLITRK4 Homo sapiens SLIT andNTRK-like family, member 4 (SLITRK4), mRNA [NM_173078] NM_002307 LGALS7Homo sapiens lectin, galactoside-binding, soluble, 7 (galectin 7)(LGALS7), mRNA [NM_002307] ENST00000325151 ENST00000325151 Smallinducible cytokine A27 precursor (CCL27) (CC chemokine ILC) (IL- 11R-alpha-locus chemokine) (Skinkine) (ESkine) (Cutaneous T-cell-attracting chemokine) (CTACK). [Source: Uniprot/SWISSPROT; Acc: Q9Y4X3][ENST00000325151] NM_006266 RALGDS Homo sapiens ral guanine nucleotidedissociation stimulator (RALGDS), transcript variant 1, mRNA [NM_006266]NM_018670 MESP1 Homo sapiens mesoderm posterior 1 homolog (mouse)(MESP1), mRNA [NM_018670] NM_004819 SYMPK Homo sapiens symplekin(SYMPK), mRNA [NM_004819] NM_175734 C17orf74 Homo sapiens chromosome 17open reading frame 74 (C17orf74), mRNA [NM_175734] J03651 J03651 HumanDF3 breast carcinoma-associated antigen mRNA, partial cds. [J03651]NM_003508 FZD9 Homo sapiens frizzled homolog 9 (Drosophila) (FZD9), mRNA[NM_003508] AL566332 AL566332 AL566332 AL566332 Homo sapiens FETAL BRAINHomo sapiens cDNA clone CS0DF015YB18 3-PRIME, mRNA sequence [AL566332]NM_203374 ZNF784 Homo sapiens zinc finger protein 784 (ZNF784), mRNA[NM_203374] ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI)(Serpin B1) (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI).[Source: Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183FOXD3 Homo sapiens forkhead box D3 (FOXD3), mRNA [NM_012183]ENST00000325371 ENST00000325371 Homo sapiens cDNA clone IMAGE: 4819956.[BC018035] THC2504037 THC2504037 ALU1_HUMAN (P39188) Alu subfamily Jsequence contamination warning entry, partial (7%) [THC2504037]NM_174903 RNF151 Homo sapiens ring finger protein 151 (RNF151), mRNA[NM_174903] ENST00000360514 ENST00000360514 Homo sapiens hypotheticalLOC339483, mRNA (cDNA clone MGC: 52427 IMAGE: 4872239), complete cds.[BC041632] NM_138763 BAX Homo sapiens BCL2-associated X protein (BAX),transcript variant delta, mRNA [NM_138763] NM_002691 POLD1 Homo sapienspolymerase (DNA directed), delta 1, catalytic subunit 125 kDa (POLD1),mRNA [NM_002691] NM_203304 RKHD1 Homo sapiens ring finger and KH domaincontaining 1 (RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiensleucine-rich repeat-containing G protein- coupled receptor 4 (LGR4),mRNA [NM_018490] CV575560 CV575560 oe37f10.y1 Human keratoconus cornea,unamplified, (od [CV575560]

TABLE 18 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻²and the log-median-ratio being at least “1” or above or being at least“−1.5” or below. The p-values were corrected using Benjamin and Hochbergmethod. GenBank Accession Gene Name Description NM_183049 TMSL3 Homosapiens thymosin-like 3 (TMSL3), mRNA [NM_183049] NM_004126 GNG11 Homosapiens guanine nucleotide binding protein (G protein), gamma 11(GNG11), mRNA [NM_004126] A_24_P530977 A_24_P530977 Unknown NM_004048B2M Homo sapiens beta-2-microglobulin (B2M), mRNA [NM_004048]NM_001005339 RGS10 Homo sapiens regulator of G-protein signalling 10(RGS10), transcript variant 1, mRNA [NM_001005339] NM_201397 GPX1 Homosapiens glutathione peroxidase 1 (GPX1), transcript variant 2, mRNA[NM_201397] NM_001032 RPS29 Homo sapiens ribosomal protein S29 (RPS29),transcript variant 1, mRNA [NM_001032] ENST00000357697 ENST00000357697Unknown XM_372498 LOC390427 PREDICTED: Homo sapiens similar toTBP-associated factor 15 isoform 1 (LOC390427), mRNA [XM_372498]NM_173078 SLITRK4 Homo sapiens SLIT and NTRK-like family, member 4(SLITRK4), mRNA [NM_173078] NM_002307 LGALS7 Homo sapiens lectin,galactoside-binding, soluble, 7 (galectin 7) (LGALS7), mRNA [NM_002307]ENST00000325151 ENST00000325151 Small inducible cytokine A27 precursor(CCL27) (CC chemokine ILC) (IL- 11 R-alpha-locus chemokine) (Skinkine)(ESkine) (Cutaneous T-cell- attracting chemokine) (CTACK). [Source:Uniprot/SWISSPROT; Acc: Q9Y4X3] [ENST00000325151] NM_006266 RALGDS Homosapiens ral guanine nucleotide dissociation stimulator (RALGDS),transcript variant 1, mRNA [NM_006266] NM_018670 MESP1 Homo sapiensmesoderm posterior 1 homolog (mouse) (MESP1), mRNA [NM_018670] NM_004819SYMPK Homo sapiens symplekin (SYMPK), mRNA [NM_004819] NM_175734C17orf74 Homo sapiens chromosome 17 open reading frame 74 (C17orf74),mRNA [NM_175734] J03651 J03651 Human DF3 breast carcinoma-associatedantigen mRNA, partial cds. [J03651] NM_003508 FZD9 Homo sapiens frizzledhomolog 9 (Drosophila) (FZD9), mRNA [NM_003508] AL566332 AL566332AL566332 AL566332 Homo sapiens FETAL BRAIN Homo sapiens cDNA cloneCS0DF015YB18 3-PRIME, mRNA sequence [AL566332] NM_203374 ZNF784 Homosapiens zinc finger protein 784 (ZNF784), mRNA [NM_203374]ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI) (Serpin B1)(Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI). [Source:Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183 FOXD3 Homosapiens forkhead box D3 (FOXD3), mRNA [NM_012183] ENST00000325371ENST00000325371 Homo sapiens cDNA clone IMAGE: 4819956. [BC018035]THC2504037 THC2504037 ALU1_HUMAN (P39188) Alu subfamily J sequencecontamination warning entry, partial (7%) [THC2504037] NM_174903 RNF151Homo sapiens ring finger protein 151 (RNF151), mRNA [NM_174903]ENST00000360514 ENST00000360514 Homo sapiens hypothetical LOC339483,mRNA (cDNA clone MGC: 52427 IMAGE: 4872239), complete cds. [BC041632]NM_138763 BAX Homo sapiens BCL2-associated X protein (BAX), transcriptvariant delta, mRNA [NM_138763] NM_002691 POLD1 Homo sapiens polymerase(DNA directed), delta 1, catalytic subunit 125 kDa (POLD1), mRNA[NM_002691] NM_203304 RKHD1 Homo sapiens ring finger and KH domaincontaining 1 (RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiensleucine-rich repeat-containing G protein- coupled receptor 4 (LGR4),mRNA [NM_018490] CV575560 CV575560 oe37f10.y1 Human keratoconus cornea,unamplified, (od [CV575560]

TABLE 19 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻²and the log-median-ratio being at least “1” or above. The p-values werecorrected using Benjamin and Hochberg method. GenBank Accession GeneName Description ENST00000357697 ENST00000357697 Unknown XM_372498LOC390427 PREDICTED: Homo sapiens similar to TBP-associated factor 15isoform 1 (LOC390427), mRNA [XM_372498] NM_173078 SLITRK4 Homo sapiensSLIT and NTRK-like family, member 4 (SLITRK4), mRNA [NM_173078]NM_002307 LGALS7 Homo sapiens lectin, galactoside-binding, soluble, 7(galectin 7) (LGALS7), mRNA [NM_002307] ENST00000325151 ENST00000325151Small inducible cytokine A27 precursor (CCL27) (CC chemokine ILC) (IL-11 R-alpha-locus chemokine) (Skinkine) (ESkine) (Cutaneous T-cell-attracting chemokine) (CTACK). [Source: Uniprot/SWISSPROT; Acc: Q9Y4X3][ENST00000325151] NM_006266 RALGDS Homo sapiens ral guanine nucleotidedissociation stimulator (RALGDS), transcript variant 1, mRNA [NM_006266]NM_018670 MESP1 Homo sapiens mesoderm posterior 1 homolog (mouse)(MESP1), mRNA [NM_018670] NM_004819 SYMPK Homo sapiens symplekin(SYMPK), mRNA [NM_004819] NM_175734 C17orf74 Homo sapiens chromosome 17open reading frame 74 (C17orf74), mRNA [NM_175734] J03651 J03651 HumanDF3 breast carcinoma-associated antigen mRNA, partial cds. [J03651]NM_003508 FZD9 Homo sapiens frizzled homolog 9 (Drosophila) (FZD9), mRNA[NM_003508] AL566332 AL566332 AL566332 AL566332 Homo sapiens FETAL BRAINHomo sapiens cDNA clone CS0DF015YB18 3-PRIME, mRNA sequence [AL566332]NM_203374 ZNF784 Homo sapiens zinc finger protein 784 (ZNF784), mRNA[NM_203374] ENST00000380739 SERPINB1 Leukocyte elastase inhibitor (LEI)(Serpin B1) (Monocyte/neutrophil elastase inhibitor) (M/NEI) (EI).[Source: Uniprot/SWISSPROT; Acc: P30740] [ENST00000380739] NM_012183FOXD3 Homo sapiens forkhead box D3 (FOXD3), mRNA [NM_012183]ENST00000325371 ENST00000325371 Homo sapiens cDNA clone IMAGE: 4819956.[BC018035] THC2504037 THC2504037 ALU1_HUMAN (P39188) Alu subfamily Jsequence contamination warning entry, partial (7%) [THC2504037]NM_174903 RNF151 Homo sapiens ring finger protein 151 (RNF151), mRNA[NM_174903] ENST00000360514 ENST00000360514 Homo sapiens hypotheticalLOC339483, mRNA (cDNA clone MGC: 52427 IMAGE: 4872239), complete cds.[BC041632] NM_138763 BAX Homo sapiens BCL2-associated X protein (BAX),transcript variant delta, mRNA [NM_138763] NM_002691 POLD1 Homo sapienspolymerase (DNA directed), delta 1, catalytic subunit 125 kDa (POLD1),mRNA [NM_002691] NM_203304 RKHD1 Homo sapiens ring finger and KH domaincontaining 1 (RKHD1), mRNA [NM_203304] NM_018490 LGR4 Homo sapiensleucine-rich repeat-containing G protein- coupled receptor 4 (LGR4),mRNA [NM_018490] CV575560 CV575560 oe37f10.y1 Human keratoconus cornea,unamplified, (od [CV575560]

TABLE 20 Gene list generated at the inclusion criteria of p ≦ 5 × 10⁻²and the log-median-ratio being at least “−1.5” or below. The p-valueswere corrected using Benjamin and Hochberg method. GenBank AccessionGene Name Description NM_001039567 RPS4Y2 Homo sapiens ribosomal proteinS4, Y-linked 2 (RPS4Y2), mRNA [NM_001039567] NM_183049 TMSL3 Homosapiens thymosin-like 3 (TMSL3), mRNA [NM_183049] NM_001008 RPS4Y1 Homosapiens ribosomal protein S4, Y-linked 1 (RPS4Y1), mRNA [NM_001008]NM_004126 GNG11 Homo sapiens guanine nucleotide binding protein (Gprotein), gamma 11 (GNG11), mRNA [NM_004126] NM_002985 CCL5 Homo sapienschemokine (C-C motif) ligand 5 (CCL5), mRNA [NM_002985] A_24_P530977A_24_P530977 Unknown NM_004048 B2M Homo sapiens beta-2-microglobulin(B2M), mRNA [NM_004048] NM_004907 IER2 Homo sapiens immediate earlyresponse 2 (IER2), mRNA [NM_004907] NM_001005339 RGS10 Homo sapiensregulator of G-protein signalling 10 (RGS10), transcript variant 1, mRNA[NM_001005339] NM_201397 GPX1 Homo sapiens glutathione peroxidase 1(GPX1), transcript variant 2, mRNA [NM_201397] NM_015646 RAP1B Homosapiens RAP1B, member of RAS oncogene family (RAP1B), transcript variant1, mRNA [NM_015646] AL049447 AL049447 Homo sapiens mRNA; cDNADKFZp586A0722 (from clone DKFZp586A0722). [AL049447] NM_031286 SH3BGRL3Homo sapiens SH3 domain binding glutamic acid-rich protein like 3(SH3BGRL3), mRNA [NM_031286] NM_012329 MMD Homo sapiens monocyte tomacrophage differentiation- associated (MMD), mRNA [NM_012329] NM_002620PF4V1 Homo sapiens platelet factor 4 variant 1 (PF4V1), mRNA [NM_002620]NM_001004 RPLP2 Homo sapiens ribosomal protein, large, P2 (RPLP2), mRNA[NM_001004] NM_033251 RPL13 Homo sapiens ribosomal protein L13 (RPL13),transcript variant 2, mRNA [NM_033251] ENST00000383061 ENST00000383061PREDICTED: Homo sapiens similar to myosin regulatory light chain-like(LOC442204), mRNA [XM_498088] NM_004907 IER2 Homo sapiens immediateearly response 2 (IER2), mRNA [NM_004907] NM_001803 CD52 Homo sapiensCD52 molecule (CD52), mRNA [NM_001803] NM_145113 MAX Homo sapiens MYCassociated factor X (MAX), transcript variant 3, mRNA [NM_145113]NM_002954 RPS27A Homo sapiens ribosomal protein S27a (RPS27A), mRNA[NM_002954] NM_006471 MRCL3 Homo sapiens myosin regulatory light chainMRCL3 (MRCL3), mRNA [NM_006471] NM_006597 HSPA8 Homo sapiens heat shock70 kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597]NM_001030 RPS27 Homo sapiens ribosomal protein S27(metallopanstimulin 1) (RPS27), mRNA [NM_001030] NM_080425 GNAS Homosapiens GNAS complex locus (GNAS), transcript variant 2, mRNA[NM_080425] NM_001032 RPS29 Homo sapiens ribosomal protein S29 (RPS29),transcript variant 1, mRNA [NM_001032] NM_001012 RPS8 Homo sapiensribosomal protein S8 (RPS8), mRNA [NM_001012] XR_017498 LOC645693PREDICTED: Homo sapiens similar to eukaryotic translation elongationfactor 1 alpha 2 (LOC645693), mRNA [XR_017498] NM_006597 HSPA8 Homosapiens heat shock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA[NM_006597] NM_001030 RPS27 Homo sapiens ribosomal protein S27(metallopanstimulin 1) (RPS27), mRNA [NM_001030] A_24_P229756A_24_P229756 Unknown THC2544911 THC2544911 MUSEFTU elongation factor Tu{Mus musculus} (exp = −1; wgp = 0; cg = 0), partial (37%) [THC2544911]NM_021104 RPL41 Homo sapiens ribosomal protein L41 (RPL41), transcriptvariant 1, mRNA [NM_021104] NM_000981 RPL19 Homo sapiens ribosomalprotein L19 (RPL19), mRNA [NM_000981] A_24_P929974 A_24_P929974 UnknownNM_002300 LDHB Homo sapiens lactate dehydrogenase B (LDHB), mRNA[NM_002300] NM_001031 RPS28 Homo sapiens ribosomal protein S28 (RPS28),mRNA [NM_001031] NM_000978 RPL23 Homo sapiens ribosomal protein L23(RPL23), mRNA [NM_000978] NM_033251 RPL13 Homo sapiens ribosomal proteinL13 (RPL13), transcript variant 2, mRNA [NM_033251] NM_001003 RPLP1 Homosapiens ribosomal protein, large, P1 (RPLP1), transcript variant 1, mRNA[NM_001003] NM_001028 RPS25 Homo sapiens ribosomal protein S25 (RPS25),mRNA [NM_001028] NM_001032 RPS29 Homo sapiens ribosomal protein S29(RPS29), transcript variant 1, mRNA [NM_001032] A_24_P238426A_24_P238426 Unknown NM_018447 TMEM111 Homo sapiens transmembraneprotein 111 (TMEM111), mRNA [NM_018447] BX096698 BX096698 BX096698Soares breast 2NbHBst Homo sapiens cDNA clone IMAGp998E11242, mRNAsequence [BX096698] NM_001003 RPLP1 Homo sapiens ribosomal protein,large, P1 (RPLP1), transcript variant 1, mRNA [NM_001003] NM_002823 PTMAHomo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA[NM_002823] NM_033251 RPL13 Homo sapiens ribosomal protein L13 (RPL13),transcript variant 2, mRNA [NM_033251] XR_017294 LOC646949 PREDICTED:Homo sapiens similar to ribosomal protein L23 (LOC646949), mRNA[XR_017294] NM_000993 RPL31 Homo sapiens ribosomal protein L31 (RPL31),mRNA [NM_000993] XR_015548 LOC729449 PREDICTED: Homo sapiens similar to60S ribosomal protein L7 (LOC729449), mRNA [XR_015548] BC052613LOC728131 Homo sapiens cDNA clone MGC: 59872 IMAGE: 6301163, completecds. [BC052613] A_24_P306968 A_24_P306968 Unknown XM_497657 LOC441876PREDICTED: Homo sapiens similar to 40S ribosomal protein S16, transcriptvariant 1 (LOC441876), mRNA [XM_497657] NM_001025 RPS23 Homo sapiensribosomal protein S23 (RPS23), mRNA [NM_001025] BU956542 BU956542BU956542 AGENCOURT_10615527 NIH_MGC_107 Homo sapiens cDNA clone IMAGE:6730153 5′, mRNA sequence [BU956542] NM_006597 HSPA8 Homo sapiens heatshock 70 kDa protein 8 (HSPA8), transcript variant 1, mRNA [NM_006597]NM_001402 EEF1A1 Homo sapiens eukaryotic translation elongation factor 1alpha 1 (EEF1A1), mRNA [NM_001402] NM_000975 RPL11 Homo sapiensribosomal protein L11 (RPL11), mRNA [NM_000975] NR_003038 SNHG5 Homosapiens small nucleolar RNA host gene (non-protein coding) 5 (SNHG5) onchromosome 6 [NR_003038] NM_015710 GLTSCR2 Homo sapiens glioma tumorsuppressor candidate region gene 2 (GLTSCR2), mRNA [NM_015710]A_24_P332292 A_24_P332292 Unknown NM_000989 RPL30 Homo sapiens ribosomalprotein L30 (RPL30), mRNA [NM_000989] NM_000989 RPL30 Homo sapiensribosomal protein L30 (RPL30), mRNA [NM_000989] CR620748 LOC729329full-length cDNA clone CS0DK011YI14 of HeLa cells Cot 25- normalized ofHomo sapiens (human) [CR620748] ENST00000337102 ENST00000337102 40Sribosomal protein S21. [Source: Uniprot/SWISSPROT; Acc: P63220][ENST00000337102] XR_018138 LOC392497 PREDICTED: Homo sapiens similar to40S ribosomal protein S6 (LOC392497), mRNA [XR_018138] NM_002341 LTBHomo sapiens lymphotoxin beta (TNF superfamily, member 3) (LTB),transcript variant 1, mRNA [NM_002341] NM_000967 RPL3 Homo sapiensribosomal protein L3 (RPL3), transcript variant 1, mRNA [NM_000967]A_24_P84408 A_24_P84408 Unknown NM_000661 RPL9 Homo sapiens ribosomalprotein L9 (RPL9), transcript variant 1, mRNA [NM_000661] NM_000991RPL28 Homo sapiens ribosomal protein L28 (RPL28), mRNA [NM_000991]NM_000661 RPL9 Homo sapiens ribosomal protein L9 (RPL9), transcriptvariant 1, mRNA [NM_000661] A_24_P50567 A_24_P50567 Unknown A_24_P298238A_24_P298238 Unknown NM_003295 TPT1 Homo sapiens tumor protein,translationally-controlled 1 (TPT1), mRNA [NM_003295] BC018140 RPS21Homo sapiens ribosomal protein S21, mRNA (cDNA clone MGC: 9438 IMAGE:3903320), complete cds. [BC018140] BC067891 LOC645683 Homo sapiens cDNAclone MGC: 87657 IMAGE: 5271409, complete cds. [BC067891] NM_001028RPS25 Homo sapiens ribosomal protein S25 (RPS25), mRNA [NM_001028]THC2567891 THC2567891 Q6NXR8_HUMAN (Q6NXR8) Ribosomal protein S3a,partial (91%) [THC2567891] NM_000988 RPL27 Homo sapiens ribosomalprotein L27 (RPL27), mRNA [NM_000988] NM_000978 RPL23 Homo sapiensribosomal protein L23 (RPL23), mRNA [NM_000978] BC001697 RPS15A Homosapiens ribosomal protein S15a, mRNA (cDNA clone MGC: 2466 IMAGE:2967511), complete cds. [BC001697] A_24_P862524 A_24_P862524 UnknownNM_001007074 RPL32 Homo sapiens ribosomal protein L32 (RPL32),transcript variant 3, mRNA [NM_001007074] A_24_P41979 A_24_P41979Unknown A_23_P210285 A_23_P210285 Unknown NM_003973 RPL14 Homo sapiensribosomal protein L14 (RPL14), transcript variant 2, mRNA [NM_003973]A_24_P255252 A_24_P255252 Unknown NM_002954 RPS27A Homo sapiensribosomal protein S27a (RPS27A), mRNA [NM_002954] NM_000984 RPL23A Homosapiens ribosomal protein L23a (RPL23A), mRNA [NM_000984] NM_001016RPS12 Homo sapiens ribosomal protein S12 (RPS12), mRNA [NM_001016]NM_003295 TPT1 Homo sapiens tumor protein, translationally-controlled 1(TPT1), mRNA [NM_003295] NM_033625 RPL34 Homo sapiens ribosomal proteinL34 (RPL34), transcript variant 2, mRNA [NM_033625] XR_015936 LOC731457PREDICTED: Homo sapiens similar to ribosomal protein S27a (LOC731457),mRNA [XR_015936] XR_018222 RPL31P4 PREDICTED: Homo sapiens ribosomalprotein L31 pseudogene 4 (RPL31P4), mRNA [XR_018222] A_24_P367063A_24_P367063 Unknown NM_001010 RPS6 Homo sapiens ribosomal protein S6(RPS6), mRNA [NM_001010] NM_033625 RPL34 Homo sapiens ribosomal proteinL34 (RPL34), transcript variant 2, mRNA [NM_033625] NM_022551 RPS18 Homosapiens ribosomal protein S18 (RPS18), mRNA [NM_022551] NM_001028 RPS25Homo sapiens ribosomal protein S25 (RPS25), mRNA [NM_001028] XR_018695RPL31P10 PREDICTED: Homo sapiens similar to ribosomal protein L31(LOC390283), mRNA [XR_018695] ENST00000356196 hCG_26523 PREDICTED: Homosapiens similar to 60S ribosomal protein L26 (LOC646161), mRNA[XR_018048] ENST00000356196 hCG_26523 PREDICTED: Homo sapiens similar to60S ribosomal protein L26 (Silica-induced gene 20 protein) (SIG-20)(LOC400055), mRNA [XM_374987] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] XR_018048LOC646161 PREDICTED: Homo sapiens similar to 60S ribosomal protein L26(LOC646161), mRNA [XR_018048] NM_003295 TPT1 Homo sapiens tumor protein,translationally-controlled 1 (TPT1), mRNA [NM_003295] NM_000986 RPL24Homo sapiens ribosomal protein L24 (RPL24), mRNA [NM_000986]ENST00000313620 LOC342994 PREDICTED: Homo sapiens similar to ribosomalprotein L34 (LOC342994), mRNA [XM_938484] THC2506377 THC2506377 HSU02032ribosomal protein L23a {Homo sapiens} (exp = −1; wgp = 0; cg = 0),partial (92%) [THC2506377] NM_002568 PABPC1 Homo sapiens poly(A) bindingprotein, cytoplasmic 1 (PABPC1), mRNA [NM_002568] NM_000997 RPL37 Homosapiens ribosomal protein L37 (RPL37), mRNA [NM_000997] XR_018303LOC648378 PREDICTED: Homo sapiens similar to ribosomal protein S14(LOC648378), mRNA [XR_018303] NM_005617 RPS14 Homo sapiens ribosomalprotein S14 (RPS14), transcript variant 3, mRNA [NM_005617] NM_001023RPS20 Homo sapiens ribosomal protein S20 (RPS20), mRNA [NM_001023]NM_003973 RPL14 Homo sapiens ribosomal protein L14 (RPL14), transcriptvariant 2, mRNA [NM_003973] NM_001006 RPS3A Homo sapiens ribosomalprotein S3A (RPS3A), mRNA [NM_001006] NM_001024 RPS21 Homo sapiensribosomal protein S21 (RPS21), mRNA [NM_001024] NM_001021 RPS17 Homosapiens ribosomal protein S17 (RPS17), mRNA [NM_001021] NM_002823 PTMAHomo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA[NM_002823]

1.-119. (canceled)
 120. An expression profile of a subject generatedfrom analysis of RNA of the subject transcribed from the genes set forthin one or more of Tables 1 through 20, wherein the RNA is extracted frommicrovesicles purified from a biological sample of the subject.
 121. Theexpression profile of claim 120, wherein the biological sample isselected from the group consisting of blood, serum, plasma and urine.122. The expression profile of claim 120, wherein the analysis comprisesdetermination of the presence or absence of the RNA transcribed from oneor more of the genes, determination of the quantitative level of the RNAtranscribed from one or more of the genes, or a combination thereof.123. The expression profile of claim 120, wherein the analysis isperformed by microarray analysis, reverse transcription PCR,quantitative PCR, or a combination thereof.
 124. The expression profileof claim 120, wherein the microvesicles are enriched for thoseoriginating from a specific cell type.
 125. The expression profile ofclaim 120, wherein the RNA is transcribed from the genes set forth inTable
 17. 126. The expression profile of claim 120, wherein the RNA istranscribed from the genes set forth in Table
 18. 127. The expressionprofile of claim 120, wherein the RNA is transcribed from the genes setforth in Table
 19. 128. The expression profile of claim 120, wherein theRNA is transcribed from the genes set forth in Table
 20. 129. A methodof generating an expression profile of a subject, comprising analyzingRNA of the subject transcribed from the genes set forth in one or moreof Tables 1 through 20, wherein the RNA is extracted from microvesiclespurified from a biological sample of the subject, and creating a reportof results generated therefrom.
 130. The method of claim 129, whereinthe biological sample is selected from the group consisting of blood,serum, plasma and urine.
 131. The method of claim 129, wherein analyzingcomprises determination of the presence or absence of the RNAtranscribed from one or more of the genes, determination of thequantitative level of the RNA transcribed from one or more of the genes,or a combination thereof.
 132. The method of claim 129, whereinanalyzing is by microarray analysis, reverse transcription PCR,quantitative PCR, or a combination thereof.
 133. The method of claim129, wherein the microvesicles are enriched for those originating from aspecific cell type.
 134. The method of claim 129, wherein the RNA istranscribed from the genes set forth in Table
 17. 135. The method ofclaim 129, wherein the RNA is transcribed from the genes set forth inTable
 18. 136. The method of claim 129, wherein the RNA is transcribedfrom the genes set forth in Table
 19. 137. The method of claim 129,wherein the RNA is transcribed from the genes set forth in Table 20.138. An oligonucleotide microarray comprising oligonucleotides thatspecifically hybridize to RNA transcribed from the genes set forth inone or more of Tables 1 through
 20. 139. A kit comprising one or morereagents for hybridizing to RNA transcribed from the genes set forth inone or more of Tables 1 through 20.